Meetings & Courses Program

Crossroads of Biology

Mouse Development, Stem Cells & Cancer
June 6 - 26, 2023

Key Dates:
Application Deadline: March 17, 2023
Arrival: June 5th by 6pm EST
Departure: June 26th around 12pm EST

CSHL Courses are intensive, running all day and often including evenings and weekends; students are expected to attend all sessions and reside on campus for the duration of the course.

Instructors:
Steve Vokes, The University of Texas at Austin
Yojiro Yamanaka, McGill University, Canada

Co-Instructors:
Danelle Devenport, Princeton University
Loydie Jerome-Majewska, McGill University, Canada

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COVID-19: All participants planning to attend in-person will be required to attest to recent COVID vaccination (within one year of the course’s start date) with an FDA or WHO approved vaccine. Additional safety measures will be in line with current NY and Federal Guidelines applicable in Summer 2023.

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See the roll of honor - who has taken the course in the past.

Follow us on Twitter @cshlmousecourse

This intensive lecture and laboratory course is designed for scientists, typically at the early principal investigator, postdoctoral or graduate stages, interested in using mouse models to study mammalian development, stem cells and cancer. The lecture portion of the course, taught by leaders in the field, provides the conceptual basis for contemporary research in embryogenesis, organogenesis in development and disease, embryonic, adult and induced pluripotent stem cells and cancer biology.

The laboratory and workshop portions of the course provide hands-on introduction to engineering of mouse models, stem cell technologies and tissue analyses. 

Experimental techniques include:
  • CRISPR/Cas9 editing and allele design 
  • Zygote microinjection and embryo transfer 
  • Isolation, culture, manipulation of pre and post-implantation embryos 
  • Zygote and embryo electroporation 
  • In vivo electroporation for somatic cancer modeling 
  • Embryo roller bottle culture 
  • In vitro fertilization 
  • ES cell directed differentiation 
  • Fluorescent RNA in situ hybridization 
  • Immunofluorescence 
  • Skeletal preparation 
  • Live imaging and confocal microscopy

2023 Speakers:
Matt Anderson, National Cancer Institute
Ripla Arora, Michigan State University
Mikala Egeblad, Cold Spring Harbor Laboratory
Paul Francois, Universite de Montreal
Diana Laird, University of California, San Francisco
Heiko Lickert, Helmholtz Munich, Germany
Jean-Leon Maitre, Institut Curie, France
Ricardo Mallarino, Princeton University
Steve Munger, Jackson Laboratory
Steve Murray, Jackson Laboratory
Virginia E. Papaioannou, Columbia University
Eszter Posfai, Princeton University
Olivier Pourquie, Harvard Medical School
Daniel Schramek, University of Toronto, Canada
Shankar Srinivas, Oxford University, UK
Rolf W. Stottmann, Nationwide Children's Hospital
Kaelyn Sumigray, Yale University
Ann Sutherland, University of Virginia
Basile Tarchini, Jackson Laboratory
Paul Trainor, Stowers Institute for Medical Research
Xin Sun, University of California, San Diego
Deneen Wellik, University of Wisconsin

Support & Stipends:

Major support provided by the National Cancer Institute of the National Institutes of Health.

We would like to acknowledge the following companies that provided invaluable support:

Microscopes: Agilent Technologies, Leica Microsystems Inc, Miltenyi Biotec, Nikon  Instruments, Inc, Thermo Fisher Scientific
Equipment: Electron Microscopy Sciences, Leica Biosystems, Thermo Fisher Scientific, Sutter Instrument Company, Eppendorf North America, Narishige International USA
Animal Donations: Charles River Laboratories, Taconic Bioscience, Inc, The Jackson Laboratory
Donations: Biolegend, Cosmo Bio Co, Ltd, Integrated DNA Technologies, Molecular Instruments, Synthego

Stipends are available to offset tuition costs as follows:

       

Please indicate your eligibility for funding in your stipend request submitted when you apply to the course. Stipend requests do not affect selection decisions made by the instructors. 

Cost (including board and lodging): $5,500

No fees are due until you have completed the full application process and are accepted into the course. 

Before applying, ensure you have:
  1. Personal statement/essay;
  2. Letter(s) of recommendation;
  3. Curriculum vitae/resume (optional);
  4. Financial aid request (optional).
    More details.

If you are not ready to fully apply but wish to express interest in applying, receive a reminder two weeks prior to the deadline, and tell us about your financial aid requirements, click below: