Systems Immunology        
April 18 - 22, 2023
Abstract Deadline: January 27, 2023


Menna Clatworthy, University of Cambridge, UK
Kathryn Miller-Jensen, Yale University
Harinder Singh, University of Pittsburgh
John Tsang, Yale University & National Institute of Allergy & Infectious Diseases

We are pleased to announce the third Cold Spring Harbor meeting on Systems Immunology. We are looking forward to a broad-based meeting, and abstracts are welcomed on all scientific topics related to systems biology approaches to normal and pathological functions of the immune system. The meeting will be held in the evening of Tuesday, April 18, and ending at noon on Saturday, April 22, 2023.

The meeting is intended to promote cross-disciplinary exchange between experimental, computational, and mathematical biologists studying the organization, functions, and regulation of the immune system at various scales. Our goal is to establish a recurrent forum that brings together immunologists and systems biologists in this nascent field.


  • Single-Cell Multi-Ome Analysis
  • Immunoreceptors: Specificities and Signaling
  • Cellular Dynamics, Interactions, and Communication
  • Modeling of Immune Signaling and Gene Regulatory Networks
  • Tissue Systems Immunology (half session)
  • Spatially Resolved Omics Analysis (half session)
  • Synthetic Immunology and Immunoengineering
  • Engineered Model Systems for Immunology
  • Systems Human Immunology

Session Chairs and Invited Speakers:

Gregoire Altan-Bonnet,
National Institutes of Health
Yvonne Chen, University of California, Los Angeles,
Nicolas Chevrier, University of Chicago
Menna Clatworthy, University of Cambridge, UK
Mark Davis, HHMI, Stanford University School of Medicine
Donna Farber, Columbia University
Deborah Fowell, Cornell University
Ronald Germain, NIAID, National Institutes of Health
Linda Griffith, Massachusetts Institute of Technology
Alexander Hoffmann, University of California, Los Angeles
Jenny Jiang, University of Pennsylvania
Christina Leslie, Memorial Sloan Kettering Cancer Center
Eoin McKinney, University of Cambridge, UK

Kathryn Miller-Jensen, Yale University
Rebecca Pompano, University of Virginia
John Ray, Benaroya Research Institute
Julio Saez-Rodriguez, Heidelberg University & EMBL, Germany
Charlotte Scott, Ghent University, Belgium
Shai Shen-Orr, Technion-Israel Institute of Technology, Israel
Harinder Singh, University of Pittsburgh
John Tsang, Yale University & NIAID, NIH

The format of the meeting will include eight oral sessions and two poster sessions. Each oral session will include invited speakers and speakers selected from submitted abstracts. For this reason, abstracts from both junior and senior investigators are warmly invited. The abstracts should focus on new and unpublished data. The organizers will select abstracts for oral or poster presentations.

We are eager to have as many young people as possible attend, and we have applied for funds from the government and industry to partially support graduate students and postdocs. All questions pertaining to registration, fees, housing, meals, transportation, visas, abstract submission, financial aid, or any other matters should be directed to Val Pakaluk.

Social Media:

The designated hashtag for this meeting is #cshlsysimm. Note that you must obtain permission from an individual presenter before live-tweeting or discussing his/her talk, poster, or research results on social media. Click the Policies tab above to see our full Confidentiality & Reporting Policy.

This conference is supported in part by the National Institute of Allergy and Infectious Diseases of the National Institutes of Health


In-Person Fees:
Academic/Media Private Room/Private Bath Package: $1705
Academic/Media Private Room/Shared Bath Package: $1600
Academic Shared Room Package: $1455
Academic/Media No-Housing Package: $1085
Student Package/Double Occupancy: $1355
Student Package/No Housing Package: $985
Corporate Private Room/Private Bath Package: $2180
Corporate No-Housing Package: $1560

*Student Housing is default double occupancy. Please inquire about availability and fees to upgrade to a private room.

NOTE: We cannot guarantee housing will be on campus.
Room packages close 2 weeks before the meeting start date

Virtual Participation: Includes access to the oral sessions via Zoom, the digital poster gallery, the Slack discussion workspace, and the Leading Strand video archive.  If you are submitting an abstract for an oral or poster presentation, please plan to attend the meeting in-person.

Presenters: Individuals submitting abstracts and facing financial barriers should firstly request financial aid (see above). Permission to present your talk or poster virtually will be given only in exceptional circumstances and on a case-by-case basis. If you think you are eligible for an exemption from the requirement to present in person, please provide a justification in writing via email to Val Pakaluk.

Non-presenting participants: We plan to broaden access to the conference by allowing certain categories of non-presenting participants to attend virtually at reduced fees. Categories include: 
1. Individuals from low & middle income countries; 
2. Individuals from non-LMIC countries in Asia, Australasia, Africa or South America; 
3. Individuals from US & Canadian minority serving institutions; 
4. Individuals with a demonstrable financial barrier; 
5. Individuals with family obligations or other special circumstances. 
For categories 4 & 5 above, please provide a justification via email to Val Pakaluk

Virtual Fees
Academic Virtual Package $325
Grad Student Virtual Package: $200
Corporate Virtual Package: $480

Late Fee (Registrations submitted after 5:00 p.m. ET on April 13)
Late Academic Virtual Package: $425
Late Student Virtual Package: $300
Corporate Virtual Package: $580