85th Cold Spring Harbor Laboratory Symposium on Quantitative Biology

Genome Stability & Integrity

May 27 - June 1, 2020
Poster Abstract Deadline: March 6, 2020


Terri Grodzicker, David Stewart & Bruce Stillman,
Cold Spring Harbor Laboratory
Symposium 2020 Poster

We are pleased to host the 85th Cold Spring Harbor Symposium which will focus on cellular and molecular mechanisms to ensure DNA/genomic stability and integrity. Previous Cold Spring Harbor Symposia have addressed many different aspects of DNA and genomic integrity, including the Symposia on Genes and Mutations (1951), Exchange of Genetic Material: Mechanism and Consequences (1958), Replication of DNA in Microorganisms (1968), DNA: Replication and Recombination (1978), Recombination at the DNA Level (1984), and Biological Responses to DNA Damage (2000).

The Symposium will begin at 7:30 pm on Wednesday May 27th, and end on Sunday evening May 31st, with normal departures on Monday morning June 1st. The Symposium will include nine oral sessions (invited speakers only) and two poster sessions providing a current synthesis of the enormous progress in our understanding of how the cellular machinery replicates and repairs the genome, and how these processes go awry in disease . The annual Dorcas Cummings lecture will take place on Saturday, May 30th. Social events throughout the Symposium provide ample opportunity for informal interactions and will include a wine-and-cheese party, a beach picnic, cocktails and banquet, and departure brunch on Monday June 1st.


  • DNA Replication & Replication Stress
  • DNA Repair Mechanisms & Connections
  • Chromosome Segregation & Stability
  • Genome Integrity in Mitosis & Meiosis
  • Gametogenesis & Early Development
  • Transposon Control and Mutational Burden
  • Diseases of Genome Instability

Invited Speakers:

Andrea Ablasser,
EPFL, Switzerland
Andres Aguilera, University of Seville, Spain
Angelika Amon, Massachusetts Institute of Technology
Jiri Bartek, Danish Cancer Society Research Center, Denmark
Dana Branzei, IFOM, Italy
Keith Caldecott, University of Sussex, UK
Karlene Cimprich, Stanford University
Don Cleveland, University of California, San Diego
David Cortez, Vanderbilt University
Alan D'Andrea, Dana-Farber Cancer Institute, Harvard Medical School
Sheila David, University of California, Davis
Titia de Lange, The Rockefeller University
Bernard De Massy, CNRS, France
John Diffley, The Francis Crick Institute, UK
Jessica Downs, The Institute of Cancer Research, UK
Daniel Durocher, Lunenfeld-Tananbaum Research Institute, Canada
Anindya Dutta, University of Virginia School of Medicine
Evan Eichler, University of Washington & HHMI
Stephen Elledge, Harvard Medical School
Cedric Feschotte, Cornell University
Susan Gasser, Friedrich Miescher Institute for Biomedical Research, Switzerland
David Gilbert, Florida State University
Roger Greenberg, University of Pennsylvania, Perelman School of Medicine
Thanos Halazonetis, University of Geneva, Switzerland
Ian Hickson, University of Copenhagen, Denmark
Andrew Jackson, MRC Human Genetics Unit, IGMM, UK
Stephen Jackson, Wellcome Trust/Cancer Research UK, Gurdon Institute, UK
Maria Jasin, Memorial Sloan-Kettering Cancer Center
Jan Karlseder, The Salk Institute
Scott Keeney, Memorial Sloan-Kettering Cancer Center & HHMI
James Lupski, Baylor College of Medicine
David MacAlpine, Duke University
Houra Merrikh, Vanderbilt University
Jo Morris, University of Birmingham, UK
Andre Nussenzweig, National Institutes of Health/NCI
Philippe Pasero, IGH, CNRS, France
Ketan Patel, MRC Laboratory of Molecular Biology, UK
David Pellman, Dana-Farber Cancer Institute
Mitinori Saitou, Kyoto University, Japan
John Schimenti, Cornell University
John Sedivy, Brown University
Agnel Sfeir, NYU School of Medicine
Agata Smogorzewska, The Rockefeller University
Bruce Stillman, Cold Spring Harbor Laboratory
Terence Strick, Ecole Normale Superieure, France
Patrick Sung, UT Health, San Antonio
Azim Surani, Wellcome Trust Cancer Research, Gurdon Institute, UK
John Tainer, UT MD Anderson Cancer Center
Maria-Elena Torres-Padilla, Institute of Epigenetics & Stem Cells, Germany
Didier Trono, EPFL, Switzerland
Johannes Walter, Harvard Medical School & HHMI
Stephen West,  The Francis Crick Institute, UK
Ting Wu, Harvard Medical School
Wei Yang, National Institutes of Health/NIDDK
Sarah Zanders, Stowers Institute for Medical Research
Xiolan Zhao, Memorial Sloan-Kettering Cancer Center
Lee Zou, Harvard Medical School

CSHL's Corporate Sponsor Program provides additional limited support for students and postdocs in need of financial support. Please apply in writing via email to Val Pakaluk and state your financial needs. Preference will be given to those who submit abstracts.

Social Media:

The designated hashtag for this meeting is #cshlsymp20. Note that you must obtain permission from an individual presenter before live-tweeting or discussing his/her talk, poster, or research results on social media. Click the Policies tab above to see our full Confidentiality & Reporting Policy.


Academic Package: $1,710
Graduate/PhD Student Package: $1,445
Corporate Package: $2,235
Academic/Student: No-Housing Package $1,140
Corporate No-Housing Package: $1,510

Regular packages are all-inclusive and cover registration, food, housing, parking, a wine-and-cheese reception, and lobster banquet. No-Housing packages include all costs except housing. Full payment is due four weeks prior to the meeting.