Eukaryotic mRNA Processing
August 22 - 26, 2023
Abstract Deadline: June 2, 2023


Javier Caceres, MRC Human Genetics Unit, University of Edinburgh, UK
Tracy Johnson,
University of California, Los Angeles
Yongsheng Shi, University of California, Irvine

We are pleased to host the fourteenth Cold Spring Harbor meeting on Eukaryotic mRNA Processing, which will begin at 7:30 pm on Tuesday, August 22 and run through lunch on Saturday, August 26, 2023. The meeting will focus on the mechanisms and regulation of mRNA splicing, polyadenylation, turnover, localization and RNA interference. It will include all aspects mRNA transport, processing and control, including ncRNA function, regulation of viral RNAs and disease implication of mRNA processing. The meeting is intended to provide a format for the exchange of ideas and information, to discuss the latest research findings and technical advances, and to facilitate interaction amongst groups active in diverse systems.


  • Mechanisms of RNA Splicing
  • Alternative Splicing: Mechanisms, Networks, and Biological Consequences
  • 3' End Processing
  • RNA Modifications
  • RNA Structure in Cells
  • Co-transcriptional RNA Processing: Dynamics of co-transcriptional RNA processing
  • RNA Turnover and Quality Control
  • Viruses and RNA Processing
  • RNA Processing in Disease
  • RNA-Protein Interactions/RNA Complexes

Keynote Speakers:

Ling-Ling Chen, Shanghai Institute of Biochemistry and Cell Biology, China
Alberto Kornblihtt, University of Buenos Aires, Buenos Aires

Discussion Leaders:

Omar Abdel-Wahab, Memorial Sloan Kettering Cancer Center
Olga Anczukow, The Jackson Laboratory
David Bentley, University of Colorado School of Medicine
John Calarco, University of Toronto, Canada
Soo-Chen Cheng, Academia Sinica, Taiwan
Sara Cherry, University of Pennsylvania
Elena Conti, Max Planck Institute, Germany
Daniel Dominguez, University of North Carolina at Chapel Hill
Ana Fiszbein, Boston University
Wojciech Galej, European Molecular Biology Laboratory, France
Richard Gregory, Harvard University
Florian Heyd, Free University, Berlin
Dan Larson, National Institutes of Health
Herve Le Hir, Institute de Biologie de l'ENS, France
Kristen Lynch, University of Pennsylvania
Nicole Martinez, Stanford University
Silvia Rouskin, Massachusetts Institute of Technology
Katja Strasser, University of Giessen, Germany
Chaolin Zhang, Columbia University
Sika Zheng, University of California, Riverside

Please bring this notice to the attention of any of your colleagues who may be interested in participating in the meeting.

All abstracts must be submitted by the abstract deadline. Late registrations may be accepted after the abstract deadline if the meeting is not oversubscribed. In the event of over-subscription, every effort will be made to ensure that all groups who wish to participate will be represented. The status (talk/poster) of abstracts will be posted on our website as soon as decisions have been made by the organizers.

We are eager to have as many young people as possible attend since they are likely to benefit most from this meeting. We have applied for funds from government and industry to partially support graduate students and postdocs. Please apply in writing via email to Samantha Mastronardi, and state your financial needs; preference will be given to those who submit abstracts.

This conference is supported in part by the National Cancer Institute of the National Institutes of Health

Social Media:

The designated hashtag for this meeting is #cshlmRNA. Note that you must obtain permission from an individual presenter before live-tweeting or discussing his/her talk, poster, or research results on social media. Click the Policies tab above to see our full Confidentiality & Reporting Policy.

In-Person Fees:

Academic/Media Private Room/Private Bath Package: $1705
Academic/Media Private Room/Shared Bath Package: $1600
Academic Shared Room Package: $1455
Academic/Media No-Housing Package: $1085
Student Package/Double Occupancy: $1355
Student Package/No Housing Package: $985
Corporate Private Room/Private Bath Package: $2180
Corporate No-Housing Package: $1560

*Student Housing is default double occupancy. Please inquire about availability and fees to upgrade to a private room.

NOTE: We cannot guarantee housing will be on campus.
Room packages close 2 weeks before the meeting start date

Virtual Participation: Includes access to the oral sessions via Zoom, the digital poster gallery, the Slack discussion workspace, and the Leading Strand video archive.  If you are submitting an abstract for an oral or poster presentation, please plan to attend the meeting in-person.

Presenters: Individuals submitting abstracts and facing financial barriers should first request financial aid (see above). Permission to present your talk or poster virtually will be given only in exceptional circumstances and on a case-by-case basis. If you think you are eligible for an exemption from the requirement to present in person, please provide a justification in writing via email to Samantha Mastronardi

Non-presenting participants: We plan to broaden access to the conference by allowing certain categories of non-presenting participants to attend virtually at reduced fees. Categories include: 
1. Individuals from low & middle-income countries; 
2. Individuals from non-LMIC countries in Asia, Australasia, Africa or South America; 
3. Individuals from US & Canadian minority-serving institutions; 
4. Individuals with a demonstrable financial barrier; 
5. Individuals with family obligations or other special circumstances. 
For categories 4 & 5 above, please provide a justification via email to Samantha Mastronardi

Virtual Fees:

Academic Virtual Package: $325
Grad Student Virtual Package: $200
Corporate Virtual Package: $480

Late Fee (Registrations submitted after 5:00 p.m. ET on August 17):

Late Academic Virtual Package: $425
Late Student Virtual Package: $300
Late Corporate Virtual Package: $580