Systems Biology: Global Regulation of Gene Expression
March 13 - 16, 2024
Abstract Deadline: January 12, 2024


Alistair Boettiger, Stanford University
Stirling Churchman, Harvard Medical School
Sara Mostafavi, University of Washington
Alexander Stark, Research Institute of Molecular Pathology, Austria

The sixteenth Cold Spring Harbor conference on Systems Biology: Global Regulation of Gene Expression will be held at Cold Spring Harbor Laboratory and begin at 7:30 pm on Wednesday,  March 13 and run through lunch on Saturday, March 16, 2024.  

The conference is intended to foster the cross-disciplinary exchange of ideas and expertise between experimentalists and computational biologists interested in the organization and control of complex transcription networks in eukaryotes. While a number of speakers have been invited, please note that the majority of oral presentations will be drawn from openly submitted abstracts.

Keynote Speakers:

Eileen Furlong, EMBL, Heidelberg, Germany
Jonathan Weissman,
Whitehead Institute and MIT/HHMI


  • Synthetic Biology
  • RNA & Splicing
  • Mechanistic Genomics
  • Chromatin
  • Single Cell Genomics & Cell-Type Mapping
  • Cis-Regulatory Code
  • AI in Genomics
  • 3D Nucleus
Confirmed Speakers:

Karen Adelman, Harvard Medical School
Lacramioara Bintu, Stanford University
Christopher Burge, Massachusetts Institute of Technology
Maria Cristina Gambetta, University of Lausanne, Switzerland
Taekjip Ha, Johns Hopkins School of Medicine
Douglas Higgs, Oxford University, UK
Valerie Hilgers, Max Planck Institute Freiburg, Germany
Rob Klose, Oxford University, UK
Arnaud Krebs, EMBL Heidelberg, Germany
Anshul Kundaje, Stanford University
Jeffrey Moffitt, Harvard Medical School
Dana Pe'er, Memorial Sloan Kettering Cancer Center
Andrew Stergachis, University of Washington
Alexander van Oudenaarden
, Hubrecht Institute, Netherlands

Abstracts should contain only new and unpublished material and must be submitted electronically by the abstract deadline. Selection of material for oral and poster presentations will be made by the organizers and individual session chairs. Status (talk/poster) of abstracts will be posted on our website as soon as decisions have been made by the organizers.

Social Media: The designated hashtag for this meeting is #cshlsysbio. Note that you must obtain permission from an individual presenter before live-tweeting or discussing his/her talk, poster, or research results on social media. Click the Policies tab above to see our full Confidentiality & Reporting Policy.

Major support for this conference is provided by the National Human Genome Research Institute, a branch of the National Institutes of Health.


In-Person Fees
Academic/Media Private Room/Private Bath Package: $1415 (Subject to availability)
Academic/Media Private Room/Shared Bath Package: $1330
Academic Shared Room Package: $1220
Academic/Media No-Housing Package: $930
Student Package*: $1125
Student No-Housing Package: $835
Corporate Private Room/Private Bath Package: $1825
Corporate No-Housing Package: $1340

*Student Housing is default double occupancy. Please enquire about availability and fees to upgrade to a private room.

Room packages close 2 weeks before the meeting start date

Rules for Virtual Participation: Virtual participation will include access to the oral sessions via Zoom, access to the digital poster sessions access to the Slack discussion channel, and the Leading Strand video archive.

Presenters: Individuals submitting abstracts and facing financial barriers should first request financial aid (see above). Permission to present your talk or poster virtually will be given only in exceptional circumstances and on a case-by-case basis. If you think you are eligible for an exemption from the requirement to present in person, please provide a justification in writing via email to Val Pakaluk

Non-presenting participants: We plan to broaden access to the conference by allowing certain categories of non-presenting participants to attend virtually at reduced fees. Categories include: 
1. Individuals from low & middle-income countries; 
2. Individuals from non-LMIC countries in Asia, Australasia, Africa or South America; 
3. Individuals from US & Canadian minority-serving institutions; 
4. Individuals with a demonstrable financial barrier; 
5. Individuals with family obligations or other special circumstances. 
For categories 4 & 5 above, please provide a justification via email to Val Pakaluk

Virtual Fees:

Academic Virtual Package: $295
Grad Student Virtual Package: $175

Corporate Virtual Package: $435

Late Fee (Registrations submitted after 5:00 p.m. ET on March 7, 2024)
Late Academic Virtual Package: $395
Late Student Virtual Package: $275
Late Corporate Virtual Package: $535