85th Cold Spring Harbor Laboratory Symposium on Quantitative Biology

Genome Stability & Integrity

May 27 - 31, 2020 (Virtual Symposium)
Poster Abstract Deadline: April 15, 2020


Terri Grodzicker, David Stewart & Bruce Stillman,
Cold Spring Harbor Laboratory
Symposium 2020 Poster

COVID-19: It is with considerable regret that we announce the cancellation of the upcoming CSHL Symposium on Genome Stability & Integrity because of ongoing concerns about the coronavirus outbreak. In an effort to prioritize our participants’ health while still promoting scientific exchange, we are hosting a virtual meeting, including oral sessions via Zoom, digital "poster sessions", dedicated Slack channel for poster and one-on-one discussions, and the Leading Strand archive after the symposium. Please check your email for updates regarding the virtual meeting, refunds, and other important details.

The 85th Cold Spring Harbor Symposium will focus on cellular and molecular mechanisms to ensure DNA/genomic stability and integrity. Previous Cold Spring Harbor Symposia have addressed many different aspects of DNA and genomic integrity, including the Symposia on Genes and Mutations (1951), Exchange of Genetic Material: Mechanism and Consequences (1958), Replication of DNA in Microorganisms (1968), DNA: Replication and Recombination (1978), Recombination at the DNA Level (1984), and Biological Responses to DNA Damage (2000).

The Symposium is going fully virtual and will now commence on Wednesday May 27 at 10 am Eastern Standard Time (EST), 2020 and end with a morning session on Sunday May 31. Oral sessions will be confined to later morning and afternoon sessions (EST) to maximize access by participants from around the world. The Symposium will include nine oral sessions (invited speakers only) and one virtual poster session throughout the Symposium providing a current synthesis of the enormous progress in our understanding of how the cellular machinery replicates and repairs the genome, and how these processes go awry in disease. 


  • DNA Replication & Replication Stress
  • DNA Repair Mechanisms & Connections
  • Chromosome Segregation & Stability
  • Genome Integrity in Mitosis & Meiosis
  • Gametogenesis & Early Development
  • Transposon Control and Mutational Burden
  • Diseases of Genome Instability

Invited Speakers (to be reconfirmed):

Andrea Ablasser,
EPFL, Switzerland
Andres Aguilera, University of Seville, Spain
Angelika Amon, Massachusetts Institute of Technology
Jiri Bartek, Danish Cancer Society Research Center, Denmark
Dana Branzei, IFOM, Italy
Keith Caldecott, University of Sussex, UK
Karlene Cimprich, Stanford University
Don Cleveland, University of California, San Diego
David Cortez, Vanderbilt University
Alan D'Andrea, Dana-Farber Cancer Institute, Harvard Medical School
Sheila David, University of California, Davis
Titia de Lange, The Rockefeller University
Bernard De Massy, CNRS, France
John Diffley, The Francis Crick Institute, UK
Jessica Downs, The Institute of Cancer Research, UK
Daniel Durocher, Lunenfeld-Tananbaum Research Institute, Canada
Anindya Dutta, University of Virginia School of Medicine
Evan Eichler, University of Washington & HHMI
Stephen Elledge, Harvard Medical School
Cedric Feschotte, Cornell University
Susan Gasser, Friedrich Miescher Institute for Biomedical Research, Switzerland
David Gilbert, Florida State University
Roger Greenberg, University of Pennsylvania, Perelman School of Medicine
Thanos Halazonetis, University of Geneva, Switzerland
Andrew Jackson, MRC Human Genetics Unit, IGMM, UK
Stephen Jackson, Wellcome Trust/Cancer Research UK, Gurdon Institute, UK
Maria Jasin, Memorial Sloan-Kettering Cancer Center
Jan Karlseder, The Salk Institute
Scott Keeney, Memorial Sloan-Kettering Cancer Center & HHMI
Jim Lupski, Baylor College of Medicine
David MacAlpine, Duke University
Houra Merrikh, Vanderbilt University
Jo Morris, University of Birmingham, UK
Andre Nussenzweig, National Institutes of Health/NCI
Philippe Pasero, IGH, CNRS, France
Ketan Patel, MRC Laboratory of Molecular Biology, UK
David Pellman, Dana-Farber Cancer Institute
Mitinori Saitou, Kyoto University, Japan
John Schimenti, Cornell University
John Sedivy, Brown University
Agnel Sfeir, NYU School of Medicine
Agata Smogorzewska, The Rockefeller University
Bruce Stillman, Cold Spring Harbor Laboratory
Terence Strick, Ecole Normale Superieure, France
Patrick Sung, UT Health, San Antonio
Azim Surani, Wellcome Trust Cancer Research, Gurdon Institute, UK
John Tainer, UT MD Anderson Cancer Center
Maria-Elena Torres-Padilla, Institute of Epigenetics & Stem Cells, Germany
Didier Trono, EPFL, Switzerland
Johannes Walter, Harvard Medical School & HHMI
Ting Wu, Harvard Medical School
Wei Yang, National Institutes of Health/NIDDK
Sarah Zanders, Stowers Institute for Medical Research
Xiolan Zhao, Memorial Sloan-Kettering Cancer Center
Lee Zou, Harvard Medical School

CSHL's Corporate Sponsor Program provides additional limited support for students and postdocs in need of financial support. Please apply in writing via email to Val Pakaluk and state your financial needs. Preference will be given to those who submit abstracts.

Social Media:

The designated hashtag for this meeting is #cshlsymp20. Note that you must obtain permission from an individual presenter before live-tweeting or discussing his/her talk, poster, or research results on social media. Click the Policies tab above to see our full Confidentiality & Reporting Policy.


Virtual Academic Package: $300
Virtual Graduate/PhD Student Package: $175

Virtual Attendance packages include registration, access to online Zoom-based oral sessions, access to the digital posters, a dedicated Slack channel and access to the video archive on the Leading Strand for ~six weeks following the meeting.