Development and 3D Modeling of the Human Brain   
December 7 - 10, 2022
Abstract Deadline: September 23, 2022


Guo-li Ming, University of Pennsylvania - Perelman School of Medicine
Sergiu Pasca, Stanford University


COVID-19: All participants planning to attend in-person will be required to provide documentary proof of full vaccination AND first booster (when eligible) with an FDA or EMA approved vaccine. Additional safety measures will be in line with current NY and federal guidelines. For more information, see COVID-19 Policies and Protocols.


We are pleased to announce the third Cold Spring Harbor Laboratory winter conference on Development and 3D Modeling of the Human Brain. The goal of this meeting is to bring together researchers from diverse fields to discuss advances in neural differentiation of pluripotent stem cells, including 3D brain organoids and assembloids, and their contribution to the understanding of human brain development, evolution and disease.

The meeting will begin on the evening of Wednesday, December 7, 2022, and end after lunch on Saturday December 10. Abstracts should contain new and unpublished material. Selection of material for oral and poster presentation will be made by the organizers and session chairs.

Sample Schedule Outline

Note: While we expect the majority of the audience including ALL oral or poster presenters to attend in-person, we recognize that travel restrictions and/or financial barriers may prevent some participants from attending. Based on our experience with virtual meetings during the COVID19 pandemic, we anticipate that some participants will be able to attend virtually, thus broadening access to the conference (see separate guidelines below for presenters and non-presenting participants). 

  • Human Brain Development and Disease
  • Human Brain Evolution
  • Brain Models, Development and Disease I
  • Brain Models, Development and Disease II
  • Brain Models and Disease

Keynote Speakers: 
Christine Mummery, Leiden University Medical Center, Netherlands
Marc Tessier-Lavigne, Stanford University

Invited Speakers:
Paola Arlotta, Harvard University
Rusty Gage, The Salk Institute for Biological Studies
Juergen Knoblich, Institute of Molecular Biology, Austria
Madeline Lancaster, MRC Laboratory of Molecular Biology, United Kingdom
Kathleen Millen, Seattle Children's Hospital
Guo-li Ming, University of Pennsylvania - Perelman School of Medicine
Hideyuki Okano, Keio University School of Medicine, Japan
Malin Parmar, Lund University, Sweden
Sergiu Pasca, Stanford University
Franck Polleux, Columbia University
Orly Reiner, Weizmann Institute of Science, Israel
Nenad Sestan, Yale University
Hongjun Song, University of Pennsylvania - Perelman School of Medicine
Lorenz Studer, Memorial Sloan Kettering Cancer Center
Sally Temple, Neural Stem Cell Institute
Giuseppe Testa, Human Technopole, Italy
Barbara Treutlein, ETH Zurich, Switzerland
Flora Vaccarino, Yale University
Pierre Vanderhaeghen, VIB-KU Leuven Center for Brain & Disease Research, Belgium

Please bring this notice to the attention of any of your colleagues who may be interested in participating in the meeting.

All abstracts must be submitted by the abstract deadline. Late registrations may be accepted after the abstract deadline if the meeting is not oversubscribed. In the event of over-subscription, every effort will be made to ensure that all groups who wish to participate will be represented. The status (talk/poster) of abstracts will be posted on our web site as soon as decisions have been made by the organizers.

We are eager to have as many young people as possible attend since they are likely to benefit most from this meeting. We have applied for funds from government and industry to partially support graduate students and postdocs. Please apply in writing via email to Val Pakaluk and state your financial needs; preference will be given to those who submit abstracts.

Social Media:

The designated hashtag for this meeting is #cshlbrain. Note that you must obtain permission from an individual presenter before live-tweeting or discussing his/her talk, poster, or research results on social media. Click the Policies tab above to see our full Confidentiality & Reporting Policy.

This meeting is sponsored by:


Academic Private Room/Private Bath Package: $1,310 (Subject to availability.)
Academic Private Room/Shared Bath Package: $1,235
Academic Shared Room Package: $1,130
Academic No-Housing Package: $860
Student Package*: $1,045
Student No-Housing Package: $775
Corporate Private Room/Private Bath Package: $1,625
Corporate No-Housing Package: $1,250

*Student Housing is default double occupancy. Please enquire about availability and fees to upgrade to private room.

Room packages close 2 weeks before the meeting start date

Rules for Virtual Participation: Virtual participation will include access to the oral sessions via Zoom, access to the digital poster sessions and access to the Slack discussion channel, and the Leading Strand video archive.

Presenters: Individuals submitting abstracts and facing financial barriers should firstly request financial aid (see above). Permission to present your talk or poster virtually will be given only in exceptional circumstances and on a case-by-case basis. If you think you are eligible for an exemption from the requirement to present in person, please provide a justification in writing via email to Val Pakaluk .

Non-presenting participants: We plan to broaden access to the conference by allowing certain categories of non-presenting participants to attend virtually at reduced fees. Categories include: 
1. Individuals from low & middle income countries; 
2. Individuals from non-LMIC countries in Asia, Australasia, Africa or South America; 
3. Individuals from US & Canadian minority serving institutions; 
4. Individuals with a demonstrable financial barrier; 
5. Individuals with family obligations or other special circumstances. 
For categories 4 & 5 above, please provide a justification via email to Val Pakaluk

Virtual Fees
Academic Virtual Package: $255
Student Virtual Package: $150
Corporate Virtual Package: $375

Late Fee (Registrations submitted after 5:00 p.m. ET on December 1, 2022)
Late Academic Virtual Package: $355
Late Student Virtual Package: $250
Late Corporate Virtual Package: $475