Blood Brain Barrier
April 3 - 6, 2019
Abstract Deadline: February 1, 2019


Dritan Agalliu, Columbia University
Chenghua Gu, Harvard Medical School
Robert Bell, Pfizer Inc.

We are pleased to announce the sixth Cold Spring Harbor conference on Blood Brain Barrier which will begin at 7:30 pm on Wednesday, April 3 and run through lunch on Saturday, April 6, 2019.

The purpose of this Cold Spring Harbor meeting is to explore and encourage new conceptual approaches and to apply novel methods to the neuroprotective physiologies of BBB structures. Our goal is pair genetic model organism biological methods with recent insights in vertebrate BBB physiology and development. We hope to create cross fertilization between fields that rarely see each other and get people thinking about how model systems can help parse the regulatory networks necessary for parsimonious BBB function.

The conference is intended to foster cross-disciplinary exchange of ideas and expertise between developmental and evolutionary biologists, vascular and BBB physiologists and disease oriented industry scientists interested in modifying or circumventing specific pathways of neuroprotection. While a number of speakers have been invited, please note that the majority of oral presentations will be drawn from openly submitted abstracts.

  • Development and Maturation of CNS Barriers
  • Imaging and Function of the BBB in Health and Disease
  • Model Systems to Study CNS Barriers
  • Cell Biology of the BBB
  • Therapy and Bioherapeutic Transport Across the BBB
  • The Gut Brain Axis and Neuroimmune Interactions
Keynote Speaker:

Ralf Adams, Max Planck Institute for Molecular Biomedicine, Germany

Invited Speakers:

Mimoun Azzouz, Boston Children's Hospital
Ruchi Bajpai, University of Southern California
Hong Chen, Boston Children's Hospital
Richard Daneman, University of California, San Diego
Elisabetta Dejana, IFOM, FIRC Institute of Molecular Oncology Foundation, Italy
Ben Deverman, Broad Instiute of MIT and Harvard
Elga deVries, MS Center Amsterdam, VU Medical Center, Netherlands
Alon Friedman, Dalhousie University, Canada
Elizabeth Hillman, Columbia University
Timothy Hla, Boston Children's Hospital
Juliette Hordeaux, University of Pennsylvania, Perelman School of Medicine
Jun Huh, Harvard Medical School
Mark Kahn, University of Pennsylvania, Perelman School of Medicine
Jonathan Kipnis, University of Virginia
Maria Lehtinen, Boston Children's Hospital
Stefan Liebner, Goethe University Clinic, Germany
Ethan Lippmann, Vanderbilt University
Axel Montagne, University of Southern California, Keck School of Medicine
Stefania Nicoli, Yale University
Birgit Obermier, Biogen
Robert Parton, University of Queensland, Australia
Daniel Reich, NIH/NINDS
Dinah Sah, Voyager Therapeutics
Amita Sehgal, The University of Pennsylvania
Julie Siegenthaler, University of Colorado
Andy Shih, Medical University of South Carolina
Clive Svendsen, Cedars-Sinai Medical Center
Michael Taylor, University of Wisconsin
Benoit Vanhollebeke, Universite Libre de Bruxelles, Belgium

Abstracts should contain interesting and exciting material and must be submitted electronically by the abstract deadline. Selection of material for oral and poster presentation will be made by the organizers and individual session chairs. Status (talk/poster) of abstracts will be posted on our web site as soon as decisions have been made by the organizers.

We are eager to have as many young people as possible attend since they are likely to benefit most from this meeting. We have applied for funds from government and industry to partially support graduate students and postdocs. Apply in writing to Maureen Morrow stating need for financial support - preference is given to those submitting abstracts.

Meeting Sponsored by:



Academic Package: $1220
Graduate/PhD Student Package: $1020
Corporate Package: $1535
Academic/Student No-Housing Package: $835
Corporate No-Housing Package: $1035

Regular packages are all-inclusive and cover registration, food, housing, parking, a wine-and-cheese party, cocktail reception, and lobster banquet. No-Housing packages include all costs except housing. Full payment is due four weeks prior to the meeting.