Yeast Genetics & Genomics
July 24 - August 13, 2018
Application Deadline: April 15, 2018


Grant Brown, University of Toronto, Canada
Elçin Ünal, University of California Berkeley
Gregory Lang, Lehigh University

See the roll of honor - who's taken the course in the past

The Yeast Genetics & Genomics course is a modern and intensive laboratory course that teaches students the full repertoire of genetic and genomic approaches needed to dissect complex problems using the yeast Saccharomy cescerevisiae. Both of classical and modern approaches are emphasized, including the isolation and characterization of mutants, tetrad analysis, and complementation. Synthetic biology is explored through CRISPR/Cas9-directed engineering of heterologous biosynthetic pathways in yeast. Students will learn genome-based methods of analysis facilitated by the Saccharomyces Genome Databaseyeast genome sequences, the gene deletion collection, and other genomic resources available to the community. Molecular genetic techniques, including yeast transformation, gene replacement by PCR, construction and analysis of gene fusions, and generation of mutations, are also emphasized.

Students will combine classical approaches with whole genome sequencing to gain experience in identifying and interpreting genetic interactions, including suppression and synthetic lethality. Students will perform genome-scale screens using the synthetic genetic array (SGA) methodology. Students will be immersed in yeast genomics and perform and interpret experiments using colony arrays and whole genome sequencing. Computational methods for data analysis are introduced. Students will gain first-hand experience in modern cytological approaches such as epitope tagging and imaging yeast cells using fluorescence microscopy with GFP-protein fusions and fluorescent indicators for different subcellular structures and organelles. Lectures on fundamental aspects of yeast genetics and genomics will be presented along with seminars given by prominent experts in the field on topics of current interest.

Please note that students are expected to attend the entire course, which spans evenings and weekends, with the exception of a day off on Sunday August 5.

Confirmed 2018 Speakers:

Angelika Amon, Massachusetts Institute of Technology
Brenda Andrews,
University of Toronto
Karen Arndt,
University of Pittsburgh
Geraldine Butler,
University College, Dublin, Ireland
Anne Donaldson, 
University of Aberdeen
Judith Frydman, Stanford University
Daniel Jarosz, Stanford University
Eric Klavins,
University of Washington
Paul Magwene,
Duke University 
Rob Nash
, Saccharomyces Genome Database, Stanford University
Fritz Roth, University of Toronto
Gavin Sherlock, Stanford University
Lorraine Symington, Columbia University
Ben Tu, University of Texas Southwestern
Sarah Zanders, Stowers Institute for Medical Research

Applications are especially welcome from:
  • Professors and instructors who wish to incorporate yeast into their undergraduate genetics classrooms
  • Scientists trained in mathematical, computational, and/or engineering disciplines who are transitioning into bench science
  • Researchers from small labs or institutions where it would otherwise be difficult to learn the fundamentals of yeast genetics/genomics

Support & Stipends

 Major support provided by the National Science Foundation

Stipends are available to offset tuition costs as follows:


US applicants (National Science Foundation)
Interdisciplinary Fellowships (transitioning from outside biology)  & Scholarships (transitioning from other biological disciplines) (Helmsley Charitable Trust)
International applicants (Howard Hughes Medical Institute)

Please indicate your eligibility for funding in your stipend request submitted when you apply to the course. Stipend requests do not affect selection decisions made by the  instructors. 

Cost (including board and lodging): $4,895

No fees are due until you have completed the full application process and are accepted into the course. Students accepted into the course should plan to arrive by early evening on July 23 and plan to depart after lunch on August 13.

Before applying, ensure you have 1) Personal statement/essay; 2) Letter(s) of recommendation; 3) Curriculum vitae/resume (optional); 4) Financial aid request (optional). More details

If you are not ready to fully apply but wish to express interest in applying, receive a reminder two weeks prior to the deadline, and tell us about your financial aid requirements, click below: