Key Dates
Application Deadline: August 15, 2025
Arrival: November 9th by 6pm EST
Departure: November 22nd around 12pm
Coursework will Begin: November 10th
CSHL Courses are intensive, running all day and often including evenings and weekends; students are expected to attend all sessions and reside on campus for the duration of the course.
Over the last decade, massively parallel DNA sequencing has markedly impacted the practice of modern biology and is being utilized in the practice of medicine. The constant improvement of these platforms means that costs and data generation timelines have been reduced by orders of magnitude, facilitating investigators to conceptualize and perform sequencing-based projects that heretofore were time-, cost-, and sample number-prohibitive. Furthermore, the application of these technologies to answer questions previously not experimentally approachable is broadening their impact and application. However, data analysis remains a complex and often vexing challenge, especially as data volumes increase.
This intensive two week course will explore use and applications of massively parallel sequencing technologies, with a focus on data analysis and bioinformatics. Students will be instructed in the detailed operation of several short- and long-read platforms, including library construction procedures, general data processing, and in-depth data analysis. A diverse range of the types of biological questions enabled by massively parallel sequencing technologies will be explored such as variant calling, transcriptome analysis, single cell analysis, metagenomics, epigenomics and others that are tailored to the student's research areas of interest.
Cloud-based computing will also be explored. Guest lecturers will highlight unique applications of these disruptive technologies.
We encourage applicants from a diversity of scientific backgrounds including molecular evolution, development, neuroscience, medicine, cancer, plant biology and microbiology.
Tracy Bedrosian, Nationwide Children’s Hospital, Columbus, OH
Wes Goar, Nationwide Children’s Hospital, Columbus, OH
Scott Handley, Washington University School of Medicine, St. Louis, MO
Peter Koo, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY
Yang Li, Washington University School of Medicine, St Louis, MO
Zachary Lippman, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY
Christopher Maher, Washington University School of Medicine, St Louis, MO
John McPherson, UC Davis, Sacramento,
Jessica Mozersky, Washington University School of Medicine, St Louis, MO
Adam Phillippy, National Human Genome Research Institute, NIH, Bethesda, MD
Trevor Pugh, University Health Network, Toronto, Canada
Aaron Quinlan, University of Utah, Salt Lake City,
Michael Schatz, Johns Hopkins University, Baltimore,
Benjamin Sunkel, Nationwide Children's Hospital, Columbus,
Sanja Vickovic, Columbia University, New York, NY
Major support provided by: National Human Genome Research Institute.
Stipends are available to offset tuition costs as follows:
Please indicate your eligibility for funding in your stipend request submitted when you apply to the course. Stipend requests do not affect selection decisions made by the instructors.
Cost (including board and lodging): $4,650 USD
No fees are due until you have completed the full application process and are accepted into the course.
Before applying, ensure you have (all due August 15):
- Personal statement/essay;
- Letter(s) of recommendation;
- Curriculum vitae/resume (optional);
- Financial aid request (optional).
More details.
If you are not ready to fully apply but wish to express interest in applying, receive a reminder two weeks prior to the deadline, and tell us about your financial aid requirements, click below:
Cold Spring Harbor Laboratory Meetings & Courses Program PO Box 100, 1 Bungtown Road Cold Spring Harbor, NY 11724-2213 Phone (516) 367-8346 Fax: (516) 367-8845 meetings@cshl.edu