Mouse Development, Stem Cells & Cancer
June 4 - 23, 2024

Key Dates:
Application Deadline: March 1, 2024
Arrival: June 4th by 6pm EST
Departure: June 23rd around 12pm EST

CSHL Courses are intensive, running all day and often including evenings and weekends; students are expected to attend all sessions and reside on campus for the duration of the course.

Instructors:
Steve Vokes, The University of Texas at Austin
Yojiro Yamanaka, McGill University, Canada

Co-Instructors:
Danelle Devenport, Princeton University
Loydie Jerome-Majewska, McGill University, Canada

See the roll of honor - who has taken the course in the past.

Follow us on Twitter @cshlmousecourse

This intensive lecture and laboratory course is designed for scientists, typically at the early principal investigator, postdoctoral or graduate stages, interested in using mouse models to study mammalian development, stem cells and cancer. The lecture portion of the course, taught by leaders in the field, provides the conceptual basis for contemporary research in embryogenesis, organogenesis in development and disease, embryonic, adult and induced pluripotent stem cells and cancer biology.

The laboratory and workshop portions of the course provide hands-on introduction to engineering of mouse models, stem cell technologies and tissue analyses. 

Experimental techniques include:

  • CRISPR/Cas9 editing and allele design 
  • Zygote microinjection and embryo transfer 
  • Isolation, culture, manipulation of pre and post-implantation embryos 
  • Zygote and embryo electroporation 
  • In vivo electroporation for somatic cancer modeling 
  • Embryo roller bottle culture 
  • In vitro fertilization 
  • ES cell directed differentiation 
  • Fluorescent RNA in situ hybridization 
  • Immunofluorescence 
  • Skeletal preparation 
  • Live imaging and confocal microscopy

2024 Speakers

Matthew Anderson, NCI-Frederick, Frederick, MD
Ripla Arora, Michigan State University, East Lansing, MI
Slobodan Beronja, Fred Hutch Cancer Center, Seattle, WA
Blanche Capel, Duke University Medical Center, Durham, NC
Kat Hadjantonakis, Memorial Sloan Kettering Cancer Center, New York, NY
Sevan Hopyan, The Hospital for Sick Children, Toronto, Canada
Bluma Lesch, Yale University, New Haven, CT
Jean-Leon Maitre, Institut Curie, Paris, France
Francesca Mariani, University of Southern California, Los Angeles, CA
Virginia Papaioannou, Columbia University Medical Center, New York, NY
Kevin Peterson, The Jackson Laboratory, Bar Harbor, ME
Eszter Posfai, Princeton University, Princeton, NJ
Pantelis Rompolas, Penn State Medicine, , PA
Bjoern Schwer, UCSF, San Francisco, San Francisco, CA
Marta Shahbazi, MRC Laboratory of Molecular Biology, Cambridge, United Kingdom
Shankar Srinivas, University of Oxford, Oxford, United Kingdom
Rolf Stottmann, Nationwide Children's Hospital Medical Center, Columbus, OH
Xin Sun, University of California, San Diego, La Jolla, CA
Paul Trainor, Stowers Institute for Medical Research, Kansas City, MO
Aaron Zorn, Children's Hospital Medical Center, Cincinnati, OH

Support & Stipends:

Major support provided by the National Cancer Institute of the National Institutes of Health.

We would like to acknowledge the following companies that provided invaluable support:

Microscopes:
 Agilent Technologies, Leica Microsystems Inc, Miltenyi Biotec, Nikon  Instruments, Inc, Thermo Fisher Scientific
Equipment: Calibre ScientificElectron Microscopy Sciences, Leica Biosystems, Thermo Fisher Scientific, Sutter Instrument Company, Eppendorf North America, Narishige International USA
Animal Donations: Charles River Laboratories, Taconic Bioscience, Inc, The Jackson Laboratory
Donations: Biolegend, Cosmo Bio Co, Ltd, Integrated DNA Technologies, Molecular Instruments, Synthego

Stipends are available to offset tuition costs as follows:

        

Please indicate your eligibility for funding in your stipend request submitted when you apply to the course. Stipend requests do not affect selection decisions made by the instructors. 

Cost (including board and lodging): $5,240 USD

No fees are due until you have completed the full application process and are accepted into the course. 

Before applying, ensure you have:
  1. Personal statement/essay;
  2. Letter(s) of recommendation;
  3. Curriculum vitae/resume (optional);
  4. Financial aid request (optional).
    More details.

If you are not ready to fully apply but wish to express interest in applying, receive a reminder two weeks prior to the deadline, and tell us about your financial aid requirements, click below: