Hypoglycemia in diabetes is a major health risk affecting patients in both the short- and long-terms.  There is a need for increased research in this area that bridges basic and clinical perspectives. The primary objective of this course is to provide an intensive discussion of the fundamentals, state-of-the-art advances and major gaps in our understanding of hypoglycemia in diabetes.  Broadly targeted at both trainees and experienced investigators, the course will combine formal presentations and informal discussions around the biochemistry, cell biology, physiology, and clinical implications of hypoglycemia.  The course will stress the recent research into the role of glucagon dysregulation during diabetes, and how this counter-regulatory hormone not only exacerbates the disease but also represents a potential new therapeutic target.  

Research on the molecular and cellular changes that occur in response to diabetes is critical in understanding and treating hypoglycemia during the disease.  With the advent of genomics, proteomics, and novel techniques in cell biology, an extraordinary opportunity now exists to develop comprehensive models of hypoglycemia from a systems physiology perspective including pancreas, liver, gut, and brain function.  This research can learn from and provide a scientific structure to clinical approaches to diagnose and treat hypoglycemia.  At a practical level, it can lead to novel molecular targets for biological treatments of diabetes. Attendees will be able to interact with senior investigators on a one-to-one basis in an informal environment. Applications are invited from medical and graduate students, postdoctoral fellows, and faculty.

Course support generously provided by: The Leona M. and Harry B. Helmsley Charitable Trust

This button links to a short form which confirms your interest in the course. No fees are due until you have completed the full application process and are accepted into the course.