Meetings & Courses Program

Crossroads of Biology

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Mouse Development, Stem Cells & Cancer
June 2 - 22, 2025

Key Dates:
Application Deadline: March 1, 2025
Arrival: June 2nd by 6pm EST
Departure: June 22nd around 12pm EST

CSHL Courses are intensive, running all day and often including evenings and weekends; students are expected to attend all sessions and reside on campus for the duration of the course.

Instructors:
Danelle Devenport, Princeton University
Loydie Jerome-Majewska, McGill University, Canada

Co-Instructors:
Matthew Anderson, NCI-Frederick, Frederick, MD 
Katherine Fantauzzo, University of Colorado Anschutz Medical Campus, Aurora, CO 

See the roll of honor - who has taken the course in the past.

Follow us on Twitter @cshlmousecourse

This intensive lecture and laboratory course is designed for scientists, typically at the early principal investigator, postdoctoral or graduate stages, interested in using mouse models to study mammalian development, stem cells and cancer. The lecture portion of the course, taught by leaders in the field, provides the conceptual basis for contemporary research in embryogenesis, organogenesis in development and disease, embryonic, adult and induced pluripotent stem cells and cancer biology.

The laboratory and workshop portions of the course provide hands-on introduction to engineering of mouse models, stem cell technologies and tissue analyses. 

Experimental techniques include:
  • CRISPR/Cas9 editing and allele design 
  • Zygote microinjection and embryo transfer 
  • Isolation, culture, manipulation of pre and post-implantation embryos 
  • Zygote and embryo electroporation 
  • In vivo electroporation for somatic cancer modeling 
  • Embryo roller bottle culture 
  • In vitro fertilization 
  • Fluorescent RNA in situ hybridization 
  • Immunofluorescence 
  • Skeletal preparation 
  • Live imaging and confocal microscopy

2025 Invited Speakers

Ripla Arora, Michigan State University, East Lansing, MI
Richard Behringer, University of Texas MD Anderson Cancer Center, Houston, TX
Jeffrey Bush, University of California, San Francisco, San Francisco, CA
Timothy Cox, University of Missouri-Kansas City, Kansas City, MO
Marissa Gredler, Harvard University, Cambridge, MA
Anna-Katerina Hadjantonakis, Sloan Kettering Institute, New York, NY
Diana Laird, University of California, San Francisco, San Francisco, CA
Francesca Mariani, University of Southern California, Los Angeles, CA
Kevin Peterson, The Jackson Laboratory, Bar Harbor, MD
Eszter Posfai, Princeton University, Princeton, NJ
Pedro Rocha, National Institutes of Health, Bethesda, MD
Licia Selleri, University of California, San Francisco, San Francisco, CA
Shyam Sharan, National Cancer Institute, NIH, Frederick, MD
Berna Sozen, Yale University, New Haven, CT
Shankar Srinivas, University of Oxford, Oxford, United Kingdom
Kaelyn Sumigray, Yale School of Medicine, New Haven, CT
Xin Sun, University of California, San Diego, La Jolla, CA
Paul Trainor, Stowers Institute for Medical Research, Kansas City
Steven Vokes, The University of Texas at Austin, Austin
Yojiro Yamanaka, Goodman Cancer Institute, McGill University, Montreal, Canada

Support & Stipends:

Major support provided by the National Cancer Institute of the National Institutes of Health.

We would like to acknowledge the following companies that provided invaluable support:

Microscopes: Agilent Technologies, Leica Microsystems Inc, Miltenyi Biotec, Nikon  Instruments, Inc, Thermo Fisher Scientific, Tomocube
Equipment: Leica Biosystems, Thermo Fisher Scientific, Sutter Instrument Company, Eppendorf North America, Narishige International USA
Animal Donations: Charles River Laboratories,  The Jackson Laboratory
Donations: Biolegend, Cosmo Bio Co, Ltd, Integrated DNA Technologies, Molecular Instruments, Synthego, Martigen

Stipends are available to offset tuition costs as follows:

        

Please indicate your eligibility for funding in your stipend request submitted when you apply to the course. Stipend requests do not affect selection decisions made by the instructors. 

Cost (including board and lodging): $6,070 USD

No fees are due until you have completed the full application process and are accepted into the course. 

Before applying, ensure you have:
  1. Personal statement/essay;
  2. Letter(s) of recommendation;
  3. Curriculum vitae/resume (optional);
  4. Financial aid request (optional).
    More details.

If you are not ready to fully apply but wish to express interest in applying, receive a reminder two weeks prior to the deadline, and tell us about your financial aid requirements, click below: