Eukaryotic DNA Replication & Genome Maintenance
September 8 - 12, 2021 Virtual
Abstract Deadline: July 9, 2021
Registrations submitted after 5:00 p.m. ET on September 2, 2021 are subject to late fees


Karlene Cimprich, Stanford University
John Diffley, The Francis Crick Institute, UK
Bob Duronio, University of North Carolina


The current COVID-19 situation is challenging and difficult for all of us - we hope this virtual conference will allow colleagues to share and discuss their latest research, while under travel and stay-at-home restrictions.


You are cordially invited to participate in the 18th meeting on EUKARYOTIC DNA REPLICATION & GENOME MAINTENANCE. We are looking forward to a broad-based meeting, and abstracts are welcomed on all aspects of replication of DNA and genomic instability in eukaryotes. The meeting will be held virtually, beginning late morning ET on Wednesday, September 8, and ending late morning ET on Sunday, September 12, 2021. The format of the meeting will include morning and afternoon sessions consisting of short talks, principally on unpublished work. In addition, there will be a poster session Friday afternoon.

Day Time (ET Session # Session Name
Wednesday 9:30 am - 12:30 pm 1 Replication Origin Control in the Cell Cycle
Wednesday 2:30 pm - 5:30 pm       2 Developmental Control of Replication and Replication Timing
Thursday 9:30 am - 12:30 pm 3 Chromatin & Genome/Nuclear Organization
Thursday 2:30 pm - 5:30 pm 4 Replication Fork Stalling, Stabilization & Checkpoint Activation
Friday 9:30 am - 12:30 pm 5 Replication Initiation Factors & Origin Activation
Friday 2:00pm - 6:00 pm
Poster Session*
Saturday 9:30 am - 12:30 pm 6 Replication-coupled Genome Instability, Cancer & Disease
Saturday 2:30 pm - 5:30 pm 7 Replication Stress and Transcription
Sunday 9:30 am - 12:30 pm 8 Fork Progression and Termination

Virtual Icebreaker
Wednesday, 6:00 pm
Discussion Zone
30-minutes following each oral session (open Zoom format)
*Virtual Poster Session will be available for viewing throughout the meeting

On-demand recordings of the daily Zoom sessions will be made available for 24 hours starting the following day, followed by longer-term access to the Leading Strand archive the week after the meeting.

Daily Schedule

City "Morning" Oral Session Poster Session "Afternoon" Oral Session
Los Angeles 6:30 am - 9:30 am 10:00 am - 11:00 am 11:30 am - 2:30 pm
New York 9:30 am - 12:30 pm 1:00 pm - 2:00 pm 2:30 pm - 5:30 pm
London 2:30 pm - 5:30 pm 6:00 pm - 7:00 pm 7:30 pm - 10:30 pm
Berlin 3:30 pm - 6:30 pm 7:00 pm - 8:00 pm 8:30 pm - 11:30 pm
Tokyo 10:30 pm - 1:30 am 2:00 am - 3:00 am 3:30 am - 6:30 am

  • Replication Initiation Mechanisms and Requirements
  • Replication Structure and Termination
  • Fork Stalling, Recovery and Generation of Mutation
  • Responses to Replication and Transcription Stress
  • Chemical Tools and Human Disease, ORC and Replication Origins
  • Origin Mapping
  • Chromatin and Replication Timing
  • Checkpoint Signaling, Stress and the Cell Cycle
    Discussion Leaders:

    Constance Alabert, University of Dundee, UK
    Oscar Aparicio, University of Southern California
    Stephen Bell, Massachusetts Institute of Technology (talk given by Shalini Gupta)
    Franziska Bleichert, Yale University School of Medicine
    Xin Chen, Johns Hopkins University
    Anne Donaldson, University of Aberdeen, UK (talk given by Shin-ichiro Hiraga)
    Aga Gambus, University of Birmingham, UK
    Pavel Janscak, University of Zurich, Switzerland
    Houra Merrikh, Vanderbilt University
    Jared Nordman, Vanderbilt University
    Patrick O'Farrell, University of California, San Francisco
    Ralph Scully, Dana Farber Cancer Institute
    Agata Smogorzeweska, The Rockefeller University
    Frank Uhlmann, The Francis Crick Institute, UK
    Antoine van Oijen, University of Wollongong, Australia
    Xiaolan Zhao, Memorial Sloan Kettering Cancer Center 

    Please bring this notice to the attention of any of your colleagues who may be interested in participating in the meeting.

    All abstracts must be submitted by the abstract deadline. Late registrations may be accepted after the abstract deadline if the meeting is not oversubscribed. In the event of over-subscription, every effort will be made to ensure that all groups who wish to participate will be represented. The status (talk/poster) of abstracts will be posted on our web site as soon as decisions have been made by the organizers.

    We are eager to have as many young people as possible attend since they are likely to benefit most from this meeting. We have applied for funds from government and industry to partially support graduate students and postdocs. Please apply in writing via email to Val Pakaluk and state your financial needs; preference will be given to those who submit abstracts.

    Social Media:

    The designated hashtag for this meeting is #cshldnarep. Note that you must obtain permission from an individual presenter before live-tweeting or discussing his/her talk, poster, or research results on social media. Click the Policies tab above to see our full Confidentiality & Reporting Policy.

    This meeting is sponsored by: TBA

    Late Fee (Registrations submitted after 5:00 p.m. ET on September 2, 2021)
    Late Virtual Academic Package: $395
    Late Virtual Graduate Student Package: $280
    Late Virtual Corporate Package: $535

    Virtual 5 day live meeting + 6 weeks archive access

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    ~48 talks / 8 sessions
    (late am/early pm)
    ~24 total hours with interactive Q&A
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    ~150 posters with
    dedicated slack channels for each poster
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    Virtual Social Events~
    Meet-the-Speakers & Editors
    Icebreaker, "Breakout" Social
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    Leading Strand video archive access to talks
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    Digital program in PDF format