Neurodegenerative Diseases: Biology & Therapeutics
November 30 - December 3, 2022
Abstract Deadline: September 16, 2022


Aaron Gitler, Stanford University
Richard Ransohoff,
Third Rock Ventures
Scott Small,
Columbia University
Li-Huei Tsai,
Massachusetts Institute of Technology

Call for Applications: TCCI Writing Fellowship - application deadline November 4, 2022


Registration for the Neurodegenerative Diseases meeting has reached full capacity.  Virtual registration remains open. If you wish to be placed on a waitlist for in-person attendance, please select the Virtual Registration (in-person waitlist) meeting price option when registering.


COVID-19: All participants planning to attend in-person will be required to provide documentary proof of full vaccination AND first booster with an FDA or EMA approved vaccine. Additional safety measures will be in line with current NY and federal guidelines. For more information, see COVID-19 Policies and Protocols.


You are cordially invited to participate in the twelfth meeting on Neurodegenerative Diseases to be held at Cold Spring Harbor Laboratory. The meeting will begin with dinner and the first session on the evening of Wednesday, November 30, 2022, and will conclude with lunch on Saturday, December 3.

A primary goal of the meeting is to provide a forum where medical scientists from academia can interact with scientists from the biopharmaceutical industry, thus forging a community of academic and industry researchers who recognize that they have much to learn from each other. Rational drug discovery for neurodegenerative diseases has begun to yield compounds and treatments that are now entering clinical settings. For human studies utilizing these compounds and treatments to be maximally informative, it is crucial that scientists from academia and industry meet regularly to exchange data and ideas.

This meeting will consist of six to seven oral sessions plus one poster session. The aim is to populate half of each oral session with speakers from academia and the other half from industry; speakers will be invited as well as selected from submitted abstracts.

  • Convergent and Divergent Pathways in Neurodegeneration
  • Glial Biology in Neurodegeneration
  • Diverse Therapeutic Strategies
  • ApoE and Lipid Metabolism
  • Cell Biology of Neurodegeneration
  • Protein Homeostasis

Keynote Speaker:
Aviv Regev,

Session Chairs:
Greg Petsko,
Brandeis University
Li Gan, Weill Cornell College of Medicine
Stacie Weninger, F-Prime Biomedical Research Initiative
David Holtzman, Washington University in St. Louis
Pete Cullen, University of Bristol, United Kingdom
Karen Duff, University College London, United Kingdom

Invited Speakers:
Aaron DiAntonio,
Washington University in St. Louis
James Surmeier, Northwestern University
Christian Haass, DZNE, Germany
Cagla Eroglu, Duke University
Tracy Yuen, Lyterian Therapeutics
Ukpong Eyo, University of Virginia
Mihaly Hajos, Cognito Therapeutics
Azad Bonni, Roche
Toby Ferguson, Biogen
Neil Shneider, Columbia University
Priyanka Narayan, NIH
Yadong Huang, University of California San Francisco
Gil Di Paolo, Denali Therapeutics
Henne Holstege, VUMC Amsterdam, Netherlands
Sabrina Simoes, Columbia University
Jessica Young, University of Washington
Mark Cookson, NIH
Randy Nixon, New York University
Mathias Jucker, University of Tubingen, Germany
Adriano Aguzzi, University of Zurich, Switzerland
Michael Ward, NINDS/NIH
Marc Diamond, UT Southwestern Medical Center

Abstracts should contain only new and unpublished material and must be submitted electronically by the abstract deadline. Selection of material for oral and poster presentations will be made by the organizers and individual session chairs. The status of abstracts (i.e., talk or poster) will be posted as soon as decisions have been made by the organizers. Please bring this announcement to the attention of any of your colleagues who may be interested in participating in the meeting.

All questions pertaining to registration, fees, housing, meals, transportation, visas, abstract submission or any other matters should be directed to Samantha Mastronardi.

Cold Spring Harbor Laboratory is eager to have as many young people as possible attend this meeting. As such, we have some funds set aside to partially support students and postdocs. Please register and apply in writing to Samantha Mastronardi stating your eligibility and need for financial support. Preference will be given to those submitting abstracts.

We look forward to seeing you at Cold Spring Harbor Laboratory at the end of November 2022.

This conference is supported in part by funds provided by the National Institute on Aging of the National Institutes of Health

This meeting is sponsored by:

Social Media: The designated hashtag for this meeting is #cshldegen. Note that you must obtain permission from an individual presenter before live-tweeting or discussing his/her talk, poster, or research results on social media. Click the Policies tab above to see our full Confidentiality & Reporting Policy.


In-Person Fees
Academic/Media Private Room/Private Bath Package: $1,310
Academic/Media Private Room/Shared Bath Package: $1,235
Academic Shared Room Package: $1,130
Academic/Media No-Housing Package: $860
Student Package*: $1,045
Student No-Housing Package: $775
Corporate Private Room/Private Bath Package: $1,625
Corporate No-Housing Package: $1,250

*Student Housing is default double occupancy. Please enquire about availability and fees to upgrade to private room.

NOTE: We cannot guarantee housing will be on campus

Room package reservations close 2 weeks before the meeting start date

Rules for Virtual Participation: Virtual participation will include access to the oral sessions via Zoom, access to the digital poster sessions and access to the Slack discussion channel, and the Leading Strand video archive.

Presenters: Individuals submitting abstracts and facing financial barriers should firstly request financial aid (see above). Permission to present your talk or poster virtually will be given only in exceptional circumstances and on a case-by-case basis. If you think you are eligible for an exemption from the requirement to present in person, please provide a justification in writing via email to Samantha Mastronardi.

Non-presenting participants: We plan to broaden access to the conference by allowing certain categories of non-presenting participants to attend virtually at reduced fees. Categories include: 
1. Individuals from low & middle income countries; 
2. Individuals from non-LMIC countries in Asia, Australasia, Africa or South America; 
3. Individuals from US & Canadian minority serving institutions; 
4. Individuals with a demonstrable financial barrier; 
5. Individuals with family obligations or other special circumstances. 
For categories 4 & 5 above, please provide a justification via email to Samantha Mastronardi

Late Fees (registrations submitted after 5:00pm ET on November 24th)

Academic Virtual Package: $355
Student Virtual Package: $250
Corporate Virtual Package: $475

Chan Zuckerberg Initiative are generously supporting the VIRTUAL participation of a limited number of individuals from Low & Middle Income Countries or US/Canadian Minority Serving Institutions
Limit: 300 attendees

Reduced Pricing for Individuals from US/Canadian Minority Serving Institutions (check eligibility): $25

Reduced Pricing for Individuals from Low & Middle Income Countries (check eligibility): $25