COVID/SARS CoV2 Rapid Research Reports #3
August 25 - 26, 2020 Virtual
Abstract Deadline: July 24
Registration Deadline: August 20 @ 4:00pm EDT


Hung Fan, University of California Irvine
Stanley Perlman, University of Iowa
Susan Weiss, University of Pennsylvania Perelman School of Medicine
David Stewart, Cold Spring Harbor Laboratory

Nearing 25 million cases of COVID, over 800,000 deaths, and economic devastation on a global scale, the world scientific community will come together for a series of virtual meetings starting on June 16th. This monthly series will bring together expert scientists on the forefront of COVID research into viral origins & variation, virus biology, host response, and antivirals & vaccines. It is designed to stimulate ideas and collaborations among scientists with the goal of hastening a solution to vanquish this worldwide disease.

COVID-R3-#1 Invited Talks only June 16 - 17, 2020
COVID-R3 #2 Invited Talks only July 21 - 22, 2020
COVID-R3 #3 Invited & Selected Talks/Posters August 25 - 26, 2020

Sessions & Confirmed Speakers (COVID-R3-#3) Times posted in US Eastern Daily Time

Session I: Host-virus Interactions/Structure
Tuesday, August 25: 9:30am EDT
Co-Chairs: Paul McCrayUniversity of Iowa & Anthony Fehr, University of Kansas

Avantika Lal, NVIDIA Corporation Genome-wide Bioinformatic Analyses Predict Key Host and Viral Factors in SARS-CoV-2 Pathogenesis
Wenlin Ren, Tsinghua University - Functional and Genetic Analysis of Viral Receptor ACE2 Orthologs Reveals Broad Potential Host Range of SARS-CoV-2
Wim van der Poel, Wageningen University & Research SARS-CoV2 Outbreaks in Farmed Mink, Netherlands April-August 2020
Jianxun Qi, Chinese Academy of Sciences, Beijing - Structural Insights of Virus Entry and Blocking by MABs and Inhibitors 
Hong Liu, Chinese Academy of Sciences, Shanghai Structure-based Design of Antiviral Drug Candidates Targeting the SARS-CoV-2 Main Protease
Yogesh Gupta, University of Texas San Antonio - Structural Basis of RNA Cap Modification by SARS-CoV-2 Coronavirus
Karla Satchell, Northwestern University - High Resolution Structures of the SARS-CoV-2 nsp16/nsp10 2’-O-methyltransferase Reveals Strategies for Structure-based Inhibitor Design

Session II: Coronavirus Biology
Tuesday, August 25: 2:00 pm EDT
Co-Chairs: Carolyn Machamer, Johns Hopkins Medical Institute & Susan Weiss, University of Pennsylvania Perelman School of Medicine

Cynthia M. Otto, University of Pennsylvania - The Scent of COVID-19: How Dogs May Help in Rapid Screening
Silvia Rouskin, Whitehead Institute, MIT Structure of the Full SARS-CoV-2 RNA Genome in Infected Cells
Yousef Alhammad, University of KansasThe SARS-CoV-2 Conserved Macrodomain is a Mono-ADP-ribosylhydrolase
Peter Kasson, University of Virginia - Unraveling Binding, Proteolytic Activation, and Entry of SARS-CoV-2 with Single-virus Microscopy
Miguel Ortiz Bezara, University of Iowa - Heterogeneous Expression of the SARS-Coronavirus-2 Receptor ACE2 in the Human Respiratory Tract
Eric Snijder, Leiden University Medical Center - The Coronavirus Escape Room
Yize Li, University of PennsylvaniaActivation of Double-stranded RNA Induced Innate Immune Responses During SARS-CoV-2 Infection

Session III:  Pathogenesis & The Immune Response
Wednesday, August 26: 9:30am EDT
Co-Chairs: Mikala Egeblad, Cold Spring Harbor Laboratory & Adrian Hayday, King's College London

Jen-Laurent Casanova, The Rockefeller University - Inborn Errors of Immunity to SARS-CoV-2
Xin Zheng, Tongji Medical College, Huazhong University of Science & Technology - SARS-CoV-2 Infection Induces Sustained Humoral Immune Responses in Convalescent Patients Following Symptomatic COVID-19
Jacob Files, University of Alabama, Birmingham -Sustained Cellular Immune Dysregulation in Non-hospitalized Individuals Recovering from SARS-CoV-2 Infection
Yin Wu, King's College LondonAge-related Antigen-receptor Dynamics of αβ and γδ T cells in SARS-CoV-2 Infection
Susan Baker, Loyola University of ChicagoCoronavirus EndoU/nsp15 Targets Viral Sequences to Evade Activating Host Sensors
Lok-Yin Roy Wong, University of Iowa - K18-hACE2 Mice for Studies of COVID-19 Treatments and Pathogenesis Including Anosmia
Michael Buchmeier, University of California, IrvineA Coronavirus Model for Virally induced Autoimmune Disease in Mice
Adrienne Randolph, Harvard University Multisystem Inflammatory Syndrome in Children (MIS-C)

Session IV:  Roundtable/Vaccines/Antivirals
Wednesday, August 26: 2:00pm EDT
Co-Chairs: Stanley Perlman, University of Iowa & Kizzmekia Corbett, National Institutes of Health

Roundtable Discussion: Role of Convalescent Plasma Therapy in COVID-19: Pros & Cons
Chair: Stanley Perlman, University of Iowa

Arturo Casadevall, John Hopkins School of Medicine Deployment of Convalescent Plasma Against COVID-19
Paul Bieniasz, The Rockefeller University - Neutralizing Antibodies in Convalescent Plasma
Adrian Hayday, Kings College London - Discussant 
Stanley Perlman, University of Iowa - Discussant

Chair: Kizzmekia Corbett, National Institutes of Health

Trevor Smith, Inovio PharmaceuticalsDurability of Antibody and T Cell Immune Responses Induced by a SARS-CoV-2 DNA Vaccine in Rhesus Macaques Animal Challenge Study
Peter Palese, Icahn School of Medicine at Mount Sinai - Newcastle Disease Virus (NDV) Expressing the Spike Protein of SARS-CoV-2 as Vaccine Candidate
David Dulin, FAU Erlangen-NurembergTargeting the SARS-CoV-2 Replicase for Antiviral Therapy: A Single-molecule Perspective
Tobias Janowitz, Cold Spring Harbor LaboratoryFamotidine Mechanism of Action and Use in Combination with Quantitative Host Symptom Tracking for COVID-19 in Non-hospitalized Patients

Virtual 2 day live meeting + archive access

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~28 talks / 4 sessions
(late am/early pm)
~12 total hours with interactive Q&A
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Virtual posters with dedicated slack channels for each poster
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Leading Strand video archive access to talks
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Twitter for meeting news & general comments

Virtual COVID-R3 #3 Package: $100
(Registrants may register for possible future COVID-R3 conferences for $85/conference)

Virtual Attendance packages include access to online Zoom-based oral sessions with live Q&A and access to the video archive on the Leading Strand for ~twelve weeks following each meeting. For registration questions please reach Alicia Franco