You are cordially invited to participate in the sixteenth biennial meeting on Mechanisms and Models of Cancer to be held at Cold Spring Harbor Laboratory. The meeting will begin on Tuesday, August 18, 2026, and will conclude with lunch on Saturday, August 22.

The format of the meeting will include morning and evening sessions consisting of eight or nine 15-minute talks per session, selected from the abstracts, principally on unpublished work. In addition, there will be two poster sessions. The organizers will decide the suitability of each abstract for oral or poster presentation, but please specify if you prefer a poster. 

Topics:

• Epigenetics
• Cancer Vulnerabilities & Therapeutic Development
• Tumor Microenvironment & Metastasis
• Cancer Metabolism
• Cell Signaling
• Genomics, Heterogeneity & Cancer Evolution
• Stem Cells, Lineage & Plasticity
• Tumor Immunology

Keynote Speakers:

Elaine Mardis, Nationwide Children's Hospital, Ohio State University
Martin McMahon, Huntsman Cancer Institute, University of Utah

Discussion Leaders:

Judith Agudo, Dana-Farber Cancer Institute
Kivanc Birsoy, The Rockefeller University
Joan Brugge, Harvard Medical School
Hongbo Chi, St. Jude Children's Research Hospital
Mark Dawson, F. Hoffmann-La Roche, Ltd., Basel, Head Pharma Research & Early Development (pRED), Switzerland
Michel DuPage, University of California, Berkeley
Margaret Goodell, Baylor College of Medicine
Ross Levine, Memorial Sloan Kettering Cancer Center
Scott Lowe, Memorial Sloan Kettering Cancer Center
Anna Obenauf, IMP, Austria
Katerina Politi, Yale University
Mallika Singh, Revolution Medicines
Chris Vakoc, St. Jude's Children's Research Hospital
Jennifer Wargo, MD Anderson Cancer Center
Rugang Zhang, MD Anderson Cancer Center
Hao Zhu, UT Southwestern University

Abstracts should contain only new and unpublished material and must be submitted electronically by the abstract deadline. Selection of material for oral and poster presentations will be made by the organizers and individual session chairs. The status of abstracts (i.e., talk or poster) will be posted as soon as decisions have been made by the organizers. Please bring this announcement to the attention of any of your colleagues who may be interested in participating in the meeting.

Financial Aid: Please apply in writing via email to Val  Pakaluk if you require financial support; preference will be given to those submitting abstracts.

Social Media: The designated hashtag for this meeting is #cshlcancer26. Note that you must obtain permission from an individual presenter before live-tweeting or discussing his/her talk, poster, or research results on social media. Click the Policies tab above to see our full Confidentiality & Reporting Policy.

This conference is supported in part by funds provided by the National Cancer Institute

In-Person Fees
Academic/Media Private Room/Private Bath Package: $1945 (Subject to Availability) 
Academic/Media Private Room/Shared Bath Package: $1820
Academic Shared Room Package: $1660
Academic/Media No-Housing Package: $1240
Student Package*: $1545
Student No-Housing Package: $1125
Corporate Private Room/Private Bath Package: $2485
Corporate No-Housing Package: $1780

*Student Housing is default double occupancy. Please enquire about availability and fees to upgrade to a private room.

NOTE: We cannot guarantee housing will be on campus

Room package reservations close 2 weeks before the meeting start date

Virtual Participation: Includes access to theoral sessions via Zoom, the digital poster gallery, the Slack discussionworkspace, and the Leading Strand video archive.  If you are submitting an abstract for an oral or poster presentation, please plan to attend the meeting in-person.

Corporate Virtual Package: $550

Late Fee (Registrations submitted after 5:00 p.m. ET on August 13, 2026)

Late Academic Virtual Package: $470
Late Student Virtual Package: $330
Late Corporate Virtual Package: $650