Mouse Development, Stem Cells & Cancer
June 8 - 28, 2016
Application Deadline: March 15, 2016
Mark Lewandoski, National Cancer Center/NIH
Deneen Wellik, University of Michigan
Benjamin Allen, University of Michigan
Amy Ralston, Michigan State University
This intensive lecture and laboratory course is designed for scientists interested in using mouse models to study mammalian development, stem cells and cancer. The lecture portion of the course, taught by leaders in the field, provides the conceptual basis for contemporary research in embryogenesis, organogenesis in development and disease, embryonic, adult and induced pluripotent stem cells and cancer biology.
The laboratory and workshop portions of the course provides hands-on introduction to engineering of mouse models, stem cell technologies and tissue analyses. Experimental techniques include genome editing by CRISPR/Cas9, pronuclear microinjection, isolation and culture/manipulation of pre- and post-implantation embryos, embryo transfer, embryo electroporation and roller bottle culture, chimera generation, generation and differentiation of mouse embryonic stem cells as well as induced pluripotent stem cells and fibroblasts, vibratome and cryosectioning, in situ RNA hybridization, immunostaining, FACS sorting and analysis, vascular injections and casting, neural sterotaxic injections, skeletal preparation, organ explant culture and fluorescent imaging, including live time-lapse microscopy.
2016 speakers include:
Ben Arenkiel, Baylor College of Medicine
Mario Capecchi, University of Utah School of Medicine
Ondine Cleaver, University of Texas Southwestern Medical Center
Frank Costantini, Columbia University
Mikala Egeblad, Cold Spring Harbor Laboratory
Dean Felsher, Stanford School of Medicine
Kat Hadjantonakis, Memorial Sloan Kettering Cancer Institute
Lindsay Hinck, University of California, Santa Cruz
Stacey Huppert, Cincinnati Children's Hospital Medical Center
Robin Lovell-Badge, MRC National Institute for Medical Research, UK
Rafi Kopan, Cincinnati Children's Hospital Medical Center
Jesse Mager, University of Massachusetts-Amherst
Ivan Maillard, University of Michigan
Licia Selleri, University of California, San Francisco
Xin Sun, University of Wisconsin, Madison
Patrick Tam, University of Sydney, Children's Medical Research Institute, Australia
David Threadgill, Texas A&M University
Paul Trainor, Stowers Institute for Medical Research
Chad Vezina, University of Wisconsin - Madison
Support & Stipends
Major support provided by the National Cancer Institute
Stipends are available to offset tuition costs as follows:
US applicants (National Cancer Institute)
Interdisciplinary Fellowships (transitioning from outside biology) & Scholarships (transitioning from other biological disciplines) (Helmsley Charitable Trust)
International applicants (Howard Hughes Medical Institute)
Please indicate your eligibility for funding in your stipend request submitted when you apply to the course. Stipend requests do not affect selection decisions made by the instructors.
Cost (including board and lodging): $4,705
This button links to a short form which confirms your interest in the course. No fees are due until you have completed the full application process and are accepted into the course.
Students accepted into the course should plan to arrive by early evening on June 7 and plan to depart after lunch on June 28.