Antibody Engineering & Display Technologies
November 9 - 22, 2021
Application Deadline: August 20, 2021

Instructors:

Christoph Rader, Scripps Research Institute
Gregg Silverman, New York University School of Medicine
     
Co-Instructor:

Gianluca Veggiani, University of Toronto, Canada 
  
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COVID-19: We anticipate that the vaccine situation may sufficiently improve to allow us to offer this meeting safely in-person.
All participants will be required to provide documentary proof of a prior FDA or EMA approved vaccine. 

International participants: BEFORE registering for the in-person conference please check your eligibility to enter the US under the current COVID-related travel restrictions

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See the roll of honor - who's taken the course in the past

Advances in the generation and selection of antibodies from combinatorial libraries allow for the rapid production of antibodies from immune and non-immune sources. This intensive laboratory/lecture course will focus on the construction of combinatorial antibody libraries expressed on the surface of filamentous phage and the subsequent selection of desired antibodies from the library. Students will learn the theoretical and practical aspects of constructing combinatorial libraries from immune and non-immune sources as well as the construction of synthetic antibody libraries. Antigen-specific recombinant monoclonal antibodies will be selected from the library. Production, purification and characterization of antibody fragments expressed in E. coli will also be covered.

The lecture series, presented by course faculty and a number of invited speakers, will emphasize theory and practice of antibody display technologies, expression of antibodies in E. coli and mammalian cells, antibody structure and function, bacterial display of antibodies and other ligand-binding domains, the immunobiology of the antibody response, and the use of monoclonal antibodies for therapy including the design of chimeric antigen receptor T cells. We will also discuss principles and protocols for generation and analysis of immune repertoires determined by Next Generation Sequencing.

Confirmed Speakers:

Brandon Dekosky, Kansas University
Ratmir Derda, University of Alberta
Birgit Dreier, University of Zurich
Shohei Koide, New York University
Mary Ann Pohl, Molecular Templates
Sachdev Sidhu, University of Toronto
Donald Siegel, University of Pennsylvania
George Smith, University of Missouri 
Stefan Stahl, Royal Swedish Institute (KTH)


We would like to acknowledge the following companies that provided invaluable support:
Equipment:
Thermo Fisher Scientific

Support & Stipends

Stipends are available to offset tuition costs as follows:

       

Interdisciplinary Fellowships (transitioning from outside biology)  & Scholarships (transitioning from other biological disciplines) (Helmsley Charitable Trust)
International applicants (Howard Hughes Medical Institute)

Please indicate your eligibility for funding in your stipend request submitted when you apply to the course. Stipend requests do not affect selection decisions made by the instructors.

Cost (including board and lodging): $4,090

Before applying, ensure you have:
  1. Personal statement/essay;
  2. Letter(s) of recommendation;
  3. Curriculum vitae/resume (optional);
  4. Financial aid request (optional).
    More details.

If you are not ready to fully apply but wish to express interest in applying, receive a reminder two weeks prior to the deadline, and tell us about your financial aid requirements, click below:

Students accepted into the course should plan to arrive by early evening on November 8 and plan to depart after lunch on November 22.