|
Presenting Author |
Abstract Title |
Talk/Poster |
|
Abadie, Kathleen V |
Heterogeneity and reversibility in CD8 T cell differentiation dynamics revealed by quantitative long-term imaging |
poster |
|
Adelaja, Adewunmi O |
Deciphering the language of immune sentinel cells to specify immune responses |
poster |
|
Aggarwal, Kunal |
Investigating potential mechanisms for negative regulation of T cell activation |
poster |
|
Alanio, Cecile |
Bystander effect of CMV latent infection on T cells |
poster |
|
Alanio, Cecile |
Skewed T cell distribution in pancreatic cancer patients |
poster |
|
Alexander, Amanda F |
Exploring IL-10 negative regulation of cell-to-cell heterogeneity in the TLR4 inflammatory response |
poster |
|
Altan-Bonnet, Grégoire |
Mapping how small differences of tumor antigenicity translate into divergent functional outcomes for T cell activation |
talk |
|
Alter, Galit |
Dissecting the antibody-OME to define novel correlates of immunity |
talk |
|
Andrabi, Syed Bilal Ahmad |
Regulation of human regulatory T cells by HIC1 |
poster |
|
Andre, Violaine |
Control of T cell responses by the accessory receptor CD6 |
poster |
|
Arber, Caroline |
Harnessing CD8 co-receptor function for immunotherapy with low-avidity TCR transgenic T cells |
talk |
|
Barski, Artem |
Co-stimulation-induced AP-1 activity is required for chromatin opening during T cell activation |
poster |
|
Bendall, Sean |
Composition and structure of human immune system to predict and control pathobiology |
talk |
|
Boutet, Marie |
Cognate antigen-stimulation promotes a specific chemokine gene-expression signature in memory CD8+T cells that is essential for protective immunity |
poster |
|
Brodin, Petter |
Systems-level analysis of immune variation and development early in life |
talk |
|
Burel, Julie G |
No cell is an island—Circulating T cell:monocyte complexes are markers of immune perturbations |
poster |
|
Carmona, Santiago J |
Towards high-resolution mapping of CD8 T cells states in melanoma tumors |
poster |
|
Cazares, Tareian A |
Modeling Epstein Barr virus transcriptional regulatory networks in lymphoblastoid cell lines |
poster |
|
Chait Berman, Karen |
Global architecture of the neural-immune network in the periphery |
poster |
|
Chan, Waipan |
Quantitative single cell temporal analysis reveals TCR regulatory mechanisms of immune checkpoint receptors |
poster |
|
Chatterjee, Budhaditya |
Immune differentiation regulator p100 tunes NF-κB responses to TNF |
poster |
|
Chavez, Michael G |
GPCR-coupled CRISPR-Cas system for engineered cell therapies |
poster |
|
Chevrier, Nicolas |
How do cells integrate multiple signals? |
talk |
|
Ciucci, Thomas |
Single-cell analysis of the epigenetic and transcriptomic landscape of memory CD4+ T cells development |
talk |
|
Cvejic, Ana |
Single-cell transcriptional analysis reveals ILC-like cells in zebrafish |
talk |
|
Das, Jishnu |
Global transcriptomic profiling uncovers unique functional roles of IgG3 B cells in HIV antiviral control |
poster |
|
Davis, Mark |
T cell repertoire, specificity and function in autoimmunity, infectious diseases and cancer |
talk |
|
Dolatshahi, Sepideh |
Systems analysis of the Fc-glycan mediated regulation of placental antibody transfer |
poster |
|
Dubovik, Tania |
Architecture of a multi-cellular polygenic network governing immune homeostasis |
poster |
|
Engler, Jan Broder |
Pregnancy enables expansion of autoreactive regulatory T cells in an animal model of multiple sclerosis |
poster |
|
Engreitz, Jesse |
Activity-by-Contact model of enhancer specificity links immune disease risk variants to target genes |
talk |
|
Farber, Donna |
Analysis of human T cells from tissues to single cells |
talk |
|
Feldman, Erik |
Microbe cocktails re-shape immunity |
poster |
|
Ferrero, Enrico |
Using regulatory genomics data to interpret the function of autoimmune disease variants and prioritise genes from expression studies |
poster |
|
Fraser, Iain |
Genome-wide screening combined with an iterative bioinformatic analysis model identifies critical roles for protein degradation and alternative splicing in TLR-induced macrophage activation |
talk |
|
Furtado, Raquel |
Expansion of circulating CXCR3lo memory CD4+ T helper cells correlates with clinical protection against human malaria |
poster |
|
Fuxman Bass, Juan I |
Comprehensive mapping of the human cytokine gene regulatory network |
poster |
|
Gaglione, Stephanie |
Silencing T cells—Inducing adaptation in CD8+ effector T cells with minimal cytokine production |
poster |
|
Galletti, Giovanni
Garton, Josh W |
Effector differentiation is predetermined among subsets of human CD8+ naïve T cells
ARID3a expression in SLE naïve B cells is associated with a distinct transcriptome |
poster
poster |
|
Germain, Ronald |
From cell microstates to 3D tissue organization—Factors controlling the operation of the immune “system” |
talk |
|
Gfeller, David |
Deep deconvolution of HLA motifs across HLA peptidomes for robust epitope predictions |
poster |
|
Gideon, Hannah P |
Deciphering multicellular microenvironment of tuberculosis lung granulomas associated with bacterial control using high-throughput single-cell mRNA sequencing |
poster |
|
Gillard, Joshua |
High-dimensional profiling of early immune events following acellular pertussis booster vaccination |
poster |
|
Gottschalk, Rachel A |
Using computational modeling to decode inflammatory stimuli at the level of MAPK activation dynamics |
poster |
|
Grigaityte, Kristina |
Public clones in the T cell repertoire of healthy humans |
poster |
|
Hacohen, Nir |
Learning the rules of the human immune system |
talk |
|
Hartmann, Felix J |
Single-cell metabolic modules organize the human T-cell activation landscape |
poster |
|
Henrickson, Sarah E |
Obesity dysregulates immunometabolic status in asthma |
poster |
|
Hilligan, Kerry L |
Dissecting the innate immune networks regulating CD4+ T cell differentiation |
talk |
|
Hirsch, Dylan C |
Fingerprinting the human immune system—Multi-disease mapping and dissection |
poster |
|
Hodgkin, Phil |
Concepts for a probabilistic cell as the basis for quantitative immune models and novel immune health diagnostics |
talk |
|
Hoffmann, Alexander |
Molecular network dynamics control hematopoetic output |
talk |
|
Hou, Lei |
Epigenomic alterations in Inflammatory Bowel Disease and Rheumatoid Arthritis across 204 individuals and 8 cell types |
poster |
|
Hu, Dan |
Dysregulation of heat shock proteins in CD4 T cells in multiple sclerosis |
poster |
|
Hu, Zicheng |
ImmPort—Building resources for repurposing of immunological data |
poster |
|
Itoh, Christopher Y |
Thioredoxin-1 is an inflammatory marker for macrophages |
poster |
|
Jain, Nikhil |
Physically driving macrophage specification and activation by microenvironmental-niche engineering |
poster |
|
Jenkins, Marc |
Plumbing the depths of the helper T cell repertoire |
talk |
|
Jiang, Jenny |
DNA-labeled pMHC tetramer based multi-parameter T cell profiling |
poster |
|
Jiang, Jenny |
High-throughput determination of the antigen specificities of T cell receptors in single cells |
talk |
|
Jiang, Peng |
Signatures of T cell dysfunction and exclusion predict cancer immunotherapy response |
poster |
|
Joglekar, Alok |
T cell antigen discovery via signaling and antigen presenting bifunctional receptors |
talk |
|
Joo, Victor |
Mode of action of anti-PD-1 antibodies on T cell signaling in human primary T cells |
poster |
|
Katoh, Hiroto |
Immunogenomic repertoire profiling reveals sulfated-glycosaminoglycans to be major and functional B-cell antigens in human malignancies |
poster |
|
Kelsey, Ilana |
Mapping individual macrophage polarization decisions by altering the timing and combination of polarization cues |
poster |
|
Kenter, Amy L. |
B cells undergoing class switch recombination become transiently BCR surface negative—Implications for the mechanism of IgE formation and for B cell pathologies |
poster |
|
Khan, Aly |
Connecting single-cell gene expression with B cell receptor specificity |
talk |
|
Kishimoto, Kensei |
Structure-function analysis of NFκB/RelA in activating endogenous target genes |
poster |
|
Kleinstein, Steven |
Analysis of B cell antibody repertoires from next-generation sequencing (in autoimmunity and other diseases) |
talk |
|
Kleinstein, Steven |
Seasonal variability and shared molecular signatures of inactivated influenza vaccination in young and older adults |
poster |
|
Koguchi, Yoshinobu |
Implementation and validation of an automated flow cytometry analysis pipeline for human immune profiling |
poster |
|
Komura, Daisuke |
Visualizing ligand-receptor-mediated interactome in single cell transcriptome data |
poster |
|
Koturan, Surya |
Role of genetic variants in innate and adaptive cell function in chronic inflammatory diseases |
poster |
|
Kueh, Hao Yuan |
How lymphocytes tell time—Insights from single-cell analysis of T-cell fate specification |
talk |
|
Kurt, Robert |
Intricacies of generating a model for dual Toll-like receptor signaling cascades |
poster |
|
Laing, Adam |
A functionally-relevant, genetically regulated immune system shape at steady-state and following challenge |
poster |
|
LaRue, Rebecca S |
Thymic regulatory T cells arise via two distinct developmental programs |
poster |
|
Lavaert, Marieke |
Single cell RNAseq reveals the in vivo differentiation potential and transcriptional dynamics of immature human thymocytes |
talk |
|
Lee, Amy H |
Transcriptional profiling of stem cell-derived macrophages provide functional insights to genome-wide association studies |
poster |
|
Lin, Jie |
Silver nanoparticles reduce pro-inflammatory effect and promote locomotor recovery after spinal cord injury |
poster |
|
Lin, Yu Sheng |
RelA dynamics during early B lymphopoiesis control B cell output and repertoire |
poster |
|
Lohmueller, Jason |
Covalent adaptor synNotch and chimeric antigen receptors (CARs) for programmable antigen targeting |
talk |
|
Lu, Jian |
Single cell RNAseq and multi-color flow cytometry analyses reveal fine compositions of human CD8+ T cells |
poster |
|
Lythe, Grant |
How many TCR clonotypes does a body maintain? |
poster |
|
Machado, Heather |
Defining the somatic mutational profiles of normal human lymphocytes |
poster |
|
Magen, Assaf |
Single-cell resolution profiling of tumor-reactive CD4+ T-cells reveals cancer-specific alterations |
poster |
|
Manczinger, Mate |
Pathogen diversity drives the evolution of generalist MHC-II alleles in human populations |
poster |
|
Mariman, Rob |
Associations between genotypes of Bordetella pertussis isolates and activation of innate and adaptive immune cells |
poster |
|
Marson, Alexander |
Reprogramming human immune cell circuitry |
talk |
|
Martin Moreno, Alba |
Design of a dendritic cell-based therapeutic vaccine against HIV-1 |
poster |
|
Martin Moreno, Alba |
Study of the effects on the vaginal immune system to ensure the biosafety of the microbicide G2-S16 |
poster |
|
Martins, Andrew J |
Integrated surface protein and gene expression analysis of cord blood mononuclear cells from pre-term and full-term births |
talk |
|
|
|
|
Milanez-Almeida, Pedro |
Blood-based prediction of lethality upon influenza infection in mice |
poster |
|
Miraldi, Emily |
Transcriptional regulatory networks that promote and restrict identities and functions of intestinal innate lymphoid cells |
talk |
|
Moss, Paul A |
' T cell versus T cell '—Single cell transcriptomic analysis of malignant and reactive T cells in patients with CD4+ lymphoma of the skin |
poster |
|
|
|
|
Mule, Matthew P |
Human vaccine response signatures revealed through simultaneous transcriptome and protein expression profiling in single cells |
poster |
|
Munoz-Rojas, Andres R |
Individual macrophages stimulated with mixed polarization cues display orthogonal secretion response programs |
talk |
|
Myers, Samuel A |
Low input proteomics enables the quantitative analysis of global gene expression in freshly isolated primary murine immune cells |
poster |
|
Napolitani, Giorgio |
Clonal analysis of typhoidal Salmonella specific effector CD4+ T cells in challenged human volunteers reveals immunodominant serovar specific and cross-reactive T cell responses |
poster |
|
Newell, Evan |
Profiling antigen-specific T cells to understand T cell diversity in human health and disease |
talk |
|
Nguyen, John |
A quantitative study of co-stimulatory signals through TNF receptor superfamily members in human CD8+ T cells |
poster |
|
Ning, Fei |
Transcription factor Hes1 attenuates type I interferon-mediated immune responses via control of VEGF-C-WDFY1 axis |
poster |
|
Normand, Rachelly |
Found in translation—A machine learning model for mouse-to-human inference |
poster |
|
ODonoghue, Geoffrey P |
Optogenetic dissection of T cell signaling dynamics and cell fate |
talk |
|
Oja, Anna E |
Functional heterogeneity of human lung CD4+ T cells |
poster |
|
Olin, Axel B |
The natural history of human immune system development during the first five years of life |
poster |
|
Ostuni, Renato |
Integration of immune stimuli in macrophages expands the range of activation states and identifies targets for functional reprogramming in cancer |
poster |
|
Palli, Rohith |
Executable models for pathway analysis of metabolomic responses to HIV vaccination |
poster |
|
Pappalardo, Jenna L |
Defining the state of immune surveillance in the homeostatic human brain |
poster |
|
Park, Kyemyung |
Exploring information transmission in gene networks using stochastic simulation and machine learning |
poster |
|
Park, Kyemyung |
Quantitative modeling of cellular interactions to dissect auto-reactive T cell responses |
poster |
|
Pettmann, Johannes |
Control of antigen discrimination by accessory receptors |
poster |
|
Prizant, Hen |
Focal perivascular regions of CXCL10 production define hubs for antigen presentation to CD4+ Th1 cells |
poster |
|
Qian, Chenxi |
scMINER—A nonlinear computational framework for clustering and network analysis of single-cell RNA-seq data |
poster |
|
Rachmaninoff, Nicholas A |
Integrative, unsupervised reconstruction of the phenotypic landscape of monogenic immune disorders |
poster |
|
Raeven, Rene |
Systems vaccinology to investigate the effect of vaccine composition and immunization route on induction of immunity against Bordetella pertussis |
poster |
|
Regev, Aviv |
Cell atlases as oadmaps to understand and treat disease |
talk |
|
Reich-Zeliger, Shlomit |
Immunity, the beginning—Characterizing immune development in preterm infants using advanced mass cytometry |
poster |
|
Reyes, Miguel |
Blood immune cell landscapes define host response signatures to bacterial infection and sepsis |
poster |
|
Richard, Arianne C |
A rate-limiting process—T cell activation from a single-cell perspective |
poster |
|
Roels, Juliette |
Transcriptional regulation of human T cell development |
poster |
|
Rogers, Dakota |
Naïve CD4 T cell heterogeneity arising from interactions with self-ligands impacts TCR signaling and Tfh differentiation following activation |
poster |
|
Rogge, Lars |
Immune response profiling reveals signaling networks mediating TNF-blocker function and correlates of therapeutic responses in spondyloarthritis |
poster |
|
Rohr, Jan C |
T cell quorum-regulation by nested antagonistic feedback circuits |
talk |
|
Rolls, Asya |
Central control of immunity or - adding neurons to complicate immunology |
talk |
|
Roy Chowdhury, Roshni |
Integrative multi-cohort systems analysis reveals immune determinants of M. tuberculosis infection outcomes and treatment response |
poster |
|
Roybal, Kole T |
Engineering the next-generation of immune cell therapies for cancer |
talk |
|
Sandu, Ioana |
Heterogeneity of virus-specific CD8 T cells in chronic viral infection |
poster |
|
Satija, Rahul |
Comprehensive integration of single cell data |
talk |
|
Scangarello, Frank A |
ADAP is an upstream regulator that precedes SLP-76 at sites of TCR engagement and stabilizes signaling microclusters |
poster |
|
Scheible, Kristin M |
Coordinated postnatal developmental trajectories of T cell and microbial structures in newborns |
talk |
|
Shen-Orr, Shai S |
Cellular variability in the immune system—Origins, dynamics and clinical implications. |
talk |
|
Siller-Farfan, Jesus A |
Immunotherapy—Designing synthetic receptors to improve T cell discrimination of antigen doses |
poster |
|
Smita, Shuchi |
Predicting transcription factor regulatory networks for naïve B cells and Memory B cell subsets |
poster |
|
Solleder, Marthe |
Deciphering the landscape of phosphorylated HLA-I ligands |
poster |
|
Steier, Zoe |
Deconstructing T cell development in the mammalian thymus with single-cell genomics |
poster |
|
Subramanian, Naeha |
A sustained small increase in NOD1 expression promotes ligand-independent oncogenic activity |
poster |
|
Suurmond, Jolien |
Derivation of ANA+ plasmablasts in lupus |
poster |
|
Taylor, Matthew D |
Combined T cell memory increases innate immunity in the cecal ligation and puncture (CLP) model of sepsis |
poster |
|
Thakore, Pratiksha |
Chromatin landscape of Th17 pathogenicity |
poster |
|
Thiemicke, Alexander |
Temporal kinetic changes of hypertonic stress differentially regulate MAPK signaling dynamics and cell fate in human immune cells |
poster |
|
Tian, Yuan |
Molecular signatures of IL-10/IFN-γ co-producing CD4 T cells during acute dengue virus infection |
poster |
|
Tovar, Adelaide E |
Dynamics of alveolar macrophage transcriptional regulation following sterile inflammation |
poster |
|
Trynka, Gosia |
Immune disease GWAS variants converge on regulation of CD4 T cell activation |
talk |
|
Ucar, Duygu |
Systems immunology uncovers sex differences in human immune system aging |
poster |
|
Villani, Alexandra-Chloe |
Single cell genomics—Using finer lenses to unravel features of human immunity |
talk |
|
Wagner, Allon |
A landscape of single-cell metabolic heterogeneity reveals novel targets for suppression of autoimmunity |
poster |
|
Wang, Linghua |
iTALK—An R Package to Characterize and Illustrate Cell-to-Cell Communications |
poster |
|
Wayman, Joseph |
Benchmarked methods for transcriptional regulatory network inference from single-cell RNA-seq data |
poster |
|
Wells, Daniel |
Genetic mechanisms associated with immune remodeling drive response to checkpoint inhibitor therapy |
poster |
|
Whalley, Thomas |
STACEI—A webtool for the structural analysis of TCR-peptide-MHC interactions |
poster |
|
Wong, Harikesh S |
Local regulatory T cell density dictates auto-reactive T cell signal integration and fate |
poster |
|
Wu, Chong |
Heterogeneity of intratumoral myeloid contexture is associated with prognosis of hepatocellular carcinoma |
poster |
|
Wu, Yusheng |
Cell innate immune response induced by disturbance of RNA splicing |
poster |
|
Youn, Ahrim |
Aging signatures of immune system in mice and their correlation with human |
poster |
|
Yu, Jiyang |
NetBID, a novel systems biology approach, identifies Hippo signaling as a “hidden” driver selectively programming CD8α+ dendritic cell activity |
poster |
|
Zhang, Tongli |
Integrating mathematical modeling and computational genomics reveals design features of a gene regulatory network controlling activated B cell dynamics |
talk |
|
Zhang, Xu Hannah |
p38β coordinates stimulatory receptor CD28 and homeostatic cytokine CD127 responses in CTCL |
poster |
|
Zhou, Wen |
Single cell analysis of mouse early thymic progenitor development and heterogeneity |
poster |
|
Zhou, Xu |
Macrophage-fibroblast cell circuitry in tissue homeostasis and inflammation |
talk |
|
Zhu, Yangyang |
The E3 ligase VHL promotes the differentiation of follicular helper T cells through glycolytic-epigenetic pathways |
poster |