Network Biology
March 19 - 23, 2019

You must register for the meeting in order to submit abstracts.
After registering you will be sent a web link for abstract submission by email.
You may copy and paste your abstract from Word, Google Docs, or Notepad; abstracts are limited to ~2900 characters.

Program information: An electronic version of the program abstract book will be sent three working days prior to the first day of the meeting, and hard copies will be available for collection upon your arrival at Cold Spring Harbor Laboratory. First night and keynote speakers are informed of their session date and time, otherwise program information is only available upon release of the electronic version of the abstract book. The reason we do this is to try and maximize interactions by encouraging participants to stay for the duration of the meeting.

Please check your email for talk length, poster instructions, and how to have your poster printed at CSHL for collection upon arrival. 

Abstract Status

Presenting Author

Abstract Title

Talk/Poster

Acar, Omer

Exploring the evolution of young gene function through genetic interaction networks

poster/lightning talk

Ali, Muhammad

Uncovering binding specificities of the Merlin and ERM family FERM domains

poster

Aloy, Patrick

Extending the small molecule similarity principle to all levels of biology

talk

AlQuraishi, Mohammed

A combinatorial grammar underlies protein-protein interactions in metazoa

talk

Al-Thani, Nayra

Determining interacting partners of FIKK kinase in the human parasite Toxoplasma gondii using AVA-seq method

poster/lightning talk

Arunachalam, Vinayagam

SignNets—Fine tuning gene-gene similarity metrics in biological systems

poster

Baudot, Anais

Mining multiplex-heterogeneous networks to study premature aging diseases

poster/lightning talk

Beltrao, Pedro

Evolution and functional relevance of eukaryotic protein phosphorylation

talk

Bhosle, Amrisha N

Identification of targets and inhibitors for methotrexate-resistant breast cancer from low cost paths in a condition specific interactome

poster/lightning talk

Billmann, Maximilian

Genome-wide identification of genetic interactions in human cells using CRISPR/Cas9

poster/lightning talk

Blum, Benjamin

Pathway and network models for proteomic and metabolomic data integration

poster

Bosdriesz, Evert

Comparative network reconstruction to identify selective anti-cancer drug combinations

poster/lightning talk

Boyault, Cyril P

SRC optogenetics meets network biology—Understanding the network dynamics of phospho-signaling accounting for distinct acto-adhesive phenotypes

poster/lightning talk

Brun, Christine G

The role of 3’UTR-protein complexes in the subcellular localisation of multifunctional proteins

talk

Buphamalai, Pisanu

Multilayered network framework for biomedical data integration and disease gene discovery

poster

Carlin, Daniel E

A fast and flexible framework for network assisted genomic association

poster/lightning talk

Chapman, Alec

Correlated transcription modules uncovered by high-precision single-cell transcriptomics

poster/lightning talk

Colic, Medina

Synthetic lethal interactions and tumor suppressor genes (TSG) as drug suppressors found in CRISPR chemogenetic screens

poster

Commins, Nicoletta A

Glucose:Galactose ratio is sensed through competitive uptake at hexose transporters in Saccharomyces cerevisiae

poster

Coruzzi, Gloria

The 4th dimension of gene regulatory networks—TIME

talk

Daakour, Sarah

Synthetic ORFeomes of Prochlorococcus marinus MED4 and NATL1A—A resource for systems-level interrogation of low- and high-light adaptations in cyanobacteria

poster

Despres, Philippe

Systematic perturbation of yeast essential genes using base editing

poster/lightning talk

Diss, Guillaume

The genetic landscape of protein-protein interaction

talk

Dozmorov, Mikhail

A method for comparing molecular coherence of phenotype-associated gene networks

poster

Dressler, Lisa

Functional compensation of epigenetic modifiers as targetable cancer vulnerabilities

poster/lightning talk

Duran Frigola, Miquel

Formatting biological big data for modern machine learning in drug discovery

poster/lightning talk

Faria do Valle, Italo

Study of the molecular determinants of disease progression in U.S. Veterans

talk

Fernandez Torras, Adria

Towards a network-driven biological knowledge integration

poster

Forster, Duncan T

Building a functional gene hierarchy of the cell

poster

Giaffar, Hamza

How does statistical complexity in the environment drive the evolutionary complexification of network structures?

poster

Goswami, Swagata

PP2A activation influences cell fate decisions in acute myeloid leukemia

poster

Gutteridge, Alex

Benchmarking network propagation methods for disease gene identification

poster

Hansen, Kasper D

Co-expression patterns define epigenetic regulators associated with neurological dysfunction

poster/lightning talk

Hart, Traver G

Discovering moonlighting proteins from human functional interaction networks

talk

Heigwer, Florian

Time-resolved mapping of genetic interactions to model rewiring of signaling pathways

talk

Hoang, Danh-Tai

Data-driven inference of hidden nodes in networks

talk

Huttenhower, Curtis

Human, microbial, and molecular interactions in the microbiome

talk

Jarosz, Dan F

Epigenetics beyond the chromosome—Heritable network rewiring by intrinsically disordered proteins

talk

Jensen, Lars J

STRING—Cross-species integration of data and text

talk

Johnson, Margaret E

Stoichiometric balance of protein copy numbers in large reversible protein interaction networks

poster/lightning talk

Khalil, Ahmad

Cooperativity and the design of complex regulatory function in synthetic circuits

talk

Kim, Eiru

Differential coessentiality reveals dynamics of biological interactions

poster

Kinney, Justin B

Measuring cis-regulatory energetics in living cells using allelic manifolds

talk

Kovacs, Istvan

Inferring functional interactions in biology

talk

Kovary, Kyle M

Identifying therapeutic targets to restore insulin sensitivity in adipose tissue through network analysis

poster

Kumar, Vivek

Multi-omics data driven systems biology using using open, extensible and scalable KBase cyber-infrastructure

poster

Landry, Christian R

Lawton, Matthew

Molecular pleiotropy contributes to the retention of heteromers of paralogs and slows down their functional divergence

Phosphoproteomic profiling of CAR T-sell signaling

talk

poster

Lee, Robin E.C.

A dynamic stimulation system to reveal the capabilities of signaling networks in single cells

talk

Lenoir, Walter F

Identifying tumor suppressor modules through genetic fitness screening data

poster

Lin, Chung-Wen

Scoring protein-protein interactions within robust network

poster

Liu, Renming

Supervised machine learning with node embeddings provide fast and accurate network-based gene classification

poster

Lorent, Julie

Estrogen receptor alpha controls gene expression via translational offsetting

talk

Ma, Cynthia Z

Transcription factor activity inference using a network model

poster

Mancuso, Christopher A

Network-guided geneset analysis of genomic data with node embeddings

poster

Mehta, Tarang K

Evolution of regulatory networks controlling adaptive traits in cichlids

talk

Morgun, Andrey

Transkingdom networks as a tool to uncover host-microbiota interactions

talk

Morohashi, Kengo

Trichome distribution pattern on Arabidopsis leaf reveals gene expression variations associated with environmental adaptation

poster

Myers, Chad L

Mapping functional networks in human cells through genome-wide analysis of genetic interactions

talk

Noyes, Marcus B

A synthetic screen of adjacent Cys2His2 zinc fingers uncovers multiple codes of specificity dependent on the geometry of engagement with the DNA

poster/lightning talk

Oertlin, Christian

Generally applicable transcriptome-wide analysis of translation using anota2seq

poster

Oeztuerk, Merve

Investigation of the regulatory network of fission yeast upon genetic perturbations

talk

Oliva, Baldo

Prediction of transcription factor binding by means of structural modeling

poster

Ooi, Lezanne

Networks in differentiation identifies selective vulnerability of pluripotent stem cells and motor neurons to ubiquitin proteasome system stress

talk

Overton, Ian M

Functionally coherent transcription factor target networks illuminate control of epithelial remodelling and oncogenic Notch

poster/lightning talk

Pei, Fen

Quantitative systems pharmacological analysis of drugs of abuse reveals the pleiotropy of targets and the effector role of mTORC1

poster

Periwal, Vipul

Expectation reflection for inferring networks of residue interactions from protein sequence alignments

poster/lightning talk

Poh, Jonathan

Experimental investigation of the human Nrf2 protein interaction network

talk

Pons, Carles

Exploring allele specific genetic interactions

poster

Porras Millan, Pablo

Capturing variation impact on molecular interactions—Updates on the IMEx Consortium mutations data set

poster

Przulj, Natasa

Mining the integrated connectedness of biomedical systems

talk

Przytycka, Teresa M

New methods for the identification of phenotype-associated mutated networks  in cancer and applications to drug response and  mutational signatures

poster

Rahman, AHM Mahfuzur

Computational methods for benchmarking interaction data from human CRISPR screens

poster

Ramadan, Stephanie A

Interactome mapping of the pathogen Helicobacter pylori using All-vs-All sequencing (AVA-seq)

poster/lightning talk

Ricci-Tam, Chiara J

Dimmer-switch signaling—An anticipation strategy in dynamic environments?

poster

Safizadeh, Hamid

Identification of targets of chemical compounds using multi-modal chemical-genetic interaction screens

poster

Sahni, Nidhi

Discovery of novel drivers of homologous recombination deficiencies by integrated network analysis

talk

Sonawane, Abhijeet R

Cell-specific gene regulatory networks using epigenetic data

poster

Srinivasan, Sanjana

Developing a network anchored functional genomics approach to identify underlying oncogenic vulnerabilities and characterize models of pancreatic cancer

poster

Stelzl, Ulrich

Protein interaction networks mediate human tyrosine kinase specificity

talk

Trigg, Shelly

Seawater temperature-influenced protein network differences in the Pacific oyster (Crassostrea gigas) during larval development

poster

van Leeuwen, Jolanda

Systematic analysis of genetic variants that bypass essential genes

talk

Vyshenska, Dariia

Inferring a combination of master regulators to control cervical cancer network

poster

Wang, Daifeng

Interpretable deep learning modeling embedding gene regulatory network for understanding neuropsychiatric disorders

talk

Wang, Wen

Systematic analysis of genetic interactions in Parkinson’s disease reveals interactions with known risk genes

poster/lightning talk

Watkins, Sarah H

Identification and preservation of trait and disease associated DNA methylation modules using two large cohorts

poster

Wittkopp, Patricia J

Impacts of mutations on regulatory networks

talk

Wunderlich, Zeba

Noise in the shadows—Mechanisms of shadow enhancer robustness in the developing Drosophila embryo

talk

Xu, Duo

Supervised learning to predict the LoF-tolerant enhancers in a unified human regulatory network

poster

Yang, Chia-Hung

Recombination induces a skewed distribution of gene regulatory networks

poster

Yu, Haiyuan

Novel algorithm and technology towards a whole-proteome 3D human interactome

talk

Yu, Jiyang

NetBID, a data-driven network-based approach, identifies Hippo signaling as a “hidden” driver selectively programming CD8α+ dendritic cell activity

poster/lightning talk

Yu, Michael

A Swiss Army knife for hierarchical modeling of biological systems

poster

Zanzoni, Andreas

A domain-resolved interaction network between bacterial secreted effectors and human proteins

poster