Presenting Author

Abstract Title

Talk/Poster

Abderrahim, Rim

Deciphering the dynamic time-course signaling network of C-type lectin receptors in primary dendritic cells

poster

Abt, Michael C

Targeted activation of IL-22-producing innate lymphoid cells enhances host resistance against Clostridioides difficile infection

talk

Acevedo-Sanchez, Yamilex

An obligate intracellular bacterial pathogen forms a direct, interkingdom membrane contact site

talk

Acosta, Ivan C

Staphylococcus aureus employs the lipoic acid salvage pathway as an atypical tactic to combat oxidative stress

poster

Adefisayo, Oyindamola

Host immunological loci underlie bacterial DNA repair pathways in Collaborative Cross mice

poster

Akbari, Madeline S

Methylglyoxal detoxification is necessary for Group B Streptococcus invasive infection

poster

Almagro-Moreno, Salvador

Modular small RNA drives pathogen emergence

talk

Alonzo, Francis

Elucidating the role of a Staphylococcal glucosaminidase in host innate immune responses

poster

Al-Tohamy, Ahmed

Burkholderia thailandensis FenI is a predicted glycosyl hydrolase with global regulatory roles in key metabolic pathways

poster

Aman, Deanna K

Characterizing the pPplA peptide pheromone that contributes to both Listeria monocytogenes vacuole escape and bacterial fitness

poster

Ambite, Ines

Immunomodulation therapy offers new molecular strategies to treat bacterial infections

poster

Ambite, Ines

The bacterial Lon protease degrades c-MYC and increases survival in two mucosal tumor models

poster

Ambite, Ines

Transcriptional inhibitor to moderate bacterial infection and mucosal inflammation

poster

Amieva, Manuel

Specialized Hideouts in the gastric glands link Helicobacter pylori persistence and disease

talk

Angara, Rajendra K

Coxiella burnetii effector protein with FFAT motifs (CbEPF1)—A novel bacterial molecular tether regulating host lipid droplet metabolism

talk

Arve-Butler, Daniel

Eosinophils promote pathogen control during chronic Salmonella infection

poster

Aufiero, Mariano A

Dectin-1/CARD9-induction of the TFEB and TFE3 gene network is dispensable for phagocyte anti-Aspergillus activity in the lung

poster

Babirye, Janet Peace

A mouse model for studying adaptive immune response to Shigella flexneri

poster

Barczak, Amy K

VPS18 contributes to phagosomal membrane integrity in Mtb-infected macrophages

poster

Basu, Ujjaini

Metal-organic framework encapsulated whole-cell vaccine facilitates antigen preservation and long-term immune protection

poster

Baylink, Arden

Bacterial vampirism mediated through chemotaxis

talk

Becker, Samuel H

Mycobacterium tuberculosis-specific CD4+ T cells promote the formation of lung macrophages and activate them through direct antigenic recognition

poster

Bee, Gavyn Chern Wei

Age-dependent differences in efferocytosis determine the outcome of opsonophagocytic protection from invasive pathogens

poster

Behnsen, Judith

Salmonella and the gut mycobiome

talk

Belboul, Amina

Estrogen promotes macrophage-mediated clearance of biofilms in an in vitro model of infected diabetic foot ulcers

poster

Bell, Samantha L

Identifying novel sensors and regulators of intracellular M. tuberculosis infection using proximity labeling approaches

poster

Bennett, Amelia B

Cryptococcus neoformans (Cn) hijacks a receptor tyrosine kinase, EphA2, to leverage mechanisms of endocytosis that facilitate its transcellular trafficking across the blood-brain barrier

talk

Berman, Judith

Genetic, physiological, and environmental influences on antifungal drug tolerance

talk

Bernshtein, Biana

Unravelling mechanisms of antibody-mediated protection against Shigella infection

poster

Bhattacharya, Madhurima

The Dengue virus protease NS2B3 cleaves cyclic GMP-AMP synthase to suppress cGAS activation

poster

Bjanes, Elisabet

The polysaccharide capsule is an essential virulence factor for a hypervirulent clinical isolate of Acinetobacter baumannii

poster

Black, Joshua J

Defining the mechanism of translation inhibition by the Legionella pneumophila effector SidL

poster

Bollinger, Christopher M

Structural and functional analyses reveal inhibitors of virulence regulators within the AraC superfamily

poster

Bollyky, Paul L

Phage diversity identifies bacterial pathogens in infected tissues

poster

Bolt, Abby E

Identification of novel phosphoinositide binding Legionella pneumophila effector proteins

poster

Boucher, Michael J

Functional genomic profiling of the fungal meningitis pathogen Cryptococcus neoformans drives mechanistic dissection of novel virulence pathways

talk

Bourgeois, Jeff S

Understanding the Lyme disease enzootic cycle—Dissecting interactions between B. burgdorferi and Ixodes scapularis with Peromyscus leucopus

poster

Brakhage, Axel

Intracellular survival of pathogenic fungi and antifungal extracellular vesicles—New mechanisms and target/tool for smart therapies

talk

Brokatzky, Dominik

Septins regulate macrophage pyroptosis and Shigella infection by controlling phosphoinositides at the plasma membrane

poster

Brothwell, Julie A

The immune response to the skin pathogen Haemophilus ducreyi in humans at single cell resolution

poster

Brouillard-Galipeau, Morgane

Understanding the role of the gut microbiota and intestinal inflammation in Parkinson’s disease

poster

Burcham, Lindsey R

Contribution of GBS manganese homeostasis and the oxidative stress response in vaginal persistence

poster

Burns, Lindsay

The bacterial virulence factor NleA undergoes host-mediated O-linked glycosylation

poster

Calise, Dante G

Endogenous oxylipins promote hyphal armament against fungicidal activity of echinocandin drugs in Aspergillus fumigatus

poster

Campbell-Kruger, Nick

A conserved two-gene operon is crucial for virulence and cell membrane function in the pathogen Mycobacterium abscessus

poster

Campbell-Valois, F-X

A small-molecule mimicking iron deprivation represses the expression of the type III secretion system in Shigella flexneri

poster

Campbell-Valois, F-X

Regulation of the type III secretion system in Shigella—A look in the rearview mirror

poster

Campos, Priscila

The E3 ubiquitin ligase Smurf2 regulates the immune response to Mycobacterium tuberculosis

poster

Castillo, Carlo

Coupling a novel anaerobic co-culture platform with single cell RNAseq—Profiling host-anaerobe interactions with greater resolution

poster

Castro, Pollyana R

Involvement of Bacteroides in the colonic hyperproliferation in response to inulin in mice

poster

Chambers, Michael J

Exploring the evolutionary arms race between human PKR and poxvirus K3

poster

Chang, Janet

A new strategy to investigate mechanisms and develop generalized tuberculosis host-response-based signatures

poster

Chang, Shu-Jung

Insight into the mechanism of action of Salmonella typhoid toxin

poster

Chang, Yuen Yan

Manipulation of the human ubiquitination by a novel virulence factor in Legionella pneumophila

poster

Chen, Nathalie

Differences in capsule and related virulence in the two clades of Klebsiella pneumoniae ST258

poster

Chen, Poyin

Shigella T3SS translocon pore interactions with host cytosolic proteins

poster

Chetrit, David

Type IV secretion systems drive lipid mixing during substrate exchange

poster

Choby, Jake

Copy number flexibility facilitates heteroresistance to increasing antibiotic pressure and threatens the beta-lactam pipeline

poster

Coady, Alison M

The antimicrobial peptide cathelicidin directs cardiac inflammation during systemic fungal infection

poster

Cohen, Shirli

Characterizing interkingdom interactions between Candida albicans and Group B Streptococcus during vaginal colonization and disease

poster

Coleman, Aja K

The Mycobacterium tuberculosis secreted protein Rv1075c hijacks host histone methyltransferases to promote infection

poster

Connor, Michael G

Pneumococcus suppresses host inflammatory response through commd2 mediated NF-κb degradation by aggrephagy

poster

Cook, Laura C

Genotypic and phenotypic characterization of Streptococcus pyogenes isolated from patients with acute pharyngitis and carriers

poster

Copin, Richard

Evolutionary trajectory of SARS-CoV-2 genome shifts during widespread vaccination and emergence of Omicron variant

poster

Curran, Sean

Great taste and less filling—Pathogen-like bacteria that increase lifespan and healthspan

poster

Dang, Eric V

Regulation of persistent fungal infection by alternatively activated macrophages

talk

Debruyne, Charline

Characterization of a new intracellular niche for Acinetobacter baumannii clinical strains

poster

Deng, Liwen

Staphylococcus aureus drives itch and scratch-induced skin damage through a V8 protease-PAR1 axis

talk

Deora, Rajendar

Moonlighting by Bps polysaccharide—A critical driver of Bordetella pertussis

poster

Di Luccia, Blanda

Gut regulatory T cells mediate immunological tolerance in Salmonella-infected super-spreader hosts

talk

Di Venanzio, Gisela A

Identifying niche specific adaptations in Acinetobacter baumannii

poster

Dias, Beatriz

The retromer complex component Snx5 functions in presentation of Mycobacterium tuberculosis antigens and anti-tuberculous host defense

poster

Dillon, Nicholas A

More than just a buffer—Host bicarbonate drives antibiotic activities

poster

Dong, Qiwen

Clinical Clostridioides difficile isolate with CdtR mutation has attenuated virulence and prevents CDI colitis in a mouse model

poster

Dong, Songyu

Photorhabdus luminescens TccC3 toxin targets the dynamic population of F-actin and impairs cell cortex integrity

poster

Dong, Songyu

Actin-binding proteins modulate the activity of actin-R177-targeting ADP-ribosylating toxins

poster

Dzierozynski, Lindsey

Inactivation of the Apc gene contributes to microbiome dysbiosis and the outgrowth of DNA-damaging bacteria

poster

El Hafi, Bassam

Investigating mechanisms of polymicrobial interactions in the cystic fibrosis lung

poster

El Husseini, Nour

Dissemination patterns of Pseudomonas aeruginosa during catheter-associated urinary tract infection

poster

El Mohtadi, Mohamed

Estrogen stimulates the clearance of wound bacteria by monocyte-derived macrophages via activation of estrogen-receptor alpha and actin cytoskeleton reorganization

poster

Elde, Nels

Recurrent genetic conflicts involving bacterial enterotoxins and bats

talk

Emam, Elhassan

A novel role of mycobacterial MutT1 in maintaining genome stability

poster

Ende, Rachel

Characterization of antibiotic interactions against K. pneumoniae in the lungs

poster

Engel, Joanne

Chlamydia trachomatis inclusion membrane protein incE employs two short linear motifs to promote its intracellular survival

talk

Eulalio, Ana

Unravelling bacterial intracellular lifestyles through microscopy‐based screenings

talk

Faiola, Nicholas

Determining the role of the Streptococcus agalactiae two component system SaeRS in vaginal colonization and metal homeostasis.

poster

Fang, Liwei

Study of MroQ-mediated post-translational modification of the quorum sensing pro-peptide AgrD

poster

Fernandes, Sheryl E

Evolved antibiotic efflux pump loss increases quorum sensing mediated virulence in Pseudomonas aeruginosa

poster

Fleeman, Renee M

Host defense peptide interactions with Klebsiella pneumoniae extracellular polysaccharides drive capsular loss and biofilm collapse

poster

Freitag, Nancy

Two permeases associated with the multifunctional CtaP cysteine transport-system in Listeria monocytogenes play distinct roles in pathogenesis

poster

Gaggioli, Margaret R

A single amino acid residue in the Salmonella effector SarA controls the strength and anti-inflammatory bias of its STAT3 activation.

talk

Gallant, Robert M

Fluoxetine promotes immunometabolic disease tolerance during polymicrobial sepsis

poster

Ganesh, Akshaya

Mycobacterial infection does not inhibit NLRP1 and CARD8 inflammasomes-induced release of IL-1ꞵ and pyroptosis

poster

Gauduin, Maeva

Characterization of a novel lipoprotein involved in meningococcal-induced endothelial dysfunction

poster

Geier, Benedikt

Spatial metabolomics at the host-pathogen interface—Visualizing the site-specific chemistry of H. pylori interactions with gastric stem cells

poster

Gholse, Aishwarya

Identification of novel drug targets against MTB infection by integrating protein-protein and TF regulatory networks

poster

Gibson, Travis E

Dynamical systems inference at ecosystem-scale reveals intrinsic instability of the dysbiotic microbiome

poster

Gilliland, Haleigh

A genome wide screen in macrophages defines host pathways required during antibiotic treatment following Mycobacterium abscesses infection

poster

Gillmore, Victoria

Immunologic synergy between purinergic receptor signaling and TIFA-dependent responses results from increased SLC-dependent cellular import of microbial heptose phosphates

poster

Goins, Lynette

The role of p22phox in macrophages in response to A. fumigatus infection

poster

Goyal, Shawn

Detection of bacterial ADP-heptose by a rare intestinal stem cell population drives epithelial regeneration from Paneth cell dedifferentiation

poster

Grossi, Marina

Legionella pneumophila effector Lpg2409 interacts with MICOS subunit Mic60 and alters host mitochondrial architecture

poster

Guo, Cynthia X

TIFA-mediated control of immunopathogenic responses

poster

Gurung, Pratibha

Characterization of  liaX in Enterococcus faecalis lysozyme resistance and biofilm formation

poster

Hamon, Melanie A.

Bacterial targeting of host chromatin, a lasting impression

talk

Harding, Christopher L

Targeting the gatekeeper of protein secretion in Mycobacterium tuberculosis.

poster

Hawkes, Colin G

First characterization of understudied periodontal pathogen Selenomonas sputigena interactions with gingival keratinocytes

poster

Hayes, Megan Hayes

Understanding bacterial neuroinvasion in a zebrafish model of tuberculosis meningitis

talk

Hernandez-Bird, Juan A

Applying the mouse pneumonia model of Acinetobacter baumannii for the evolution and characterization of colistin-selected mutants

poster

Hilbert, Zoe A

Uncovering the evolutionary mechanisms of host adaptation in a human fungal pathogen

poster

Hoffman, Alexandria

Macrophage biomimetic nanoparticles as an cytoprotective therapy in bacterial sepsis

poster

Hooper, Lora

The gut microbiota reprograms intestinal lipid metabolism through long non-coding RNA Snhg9

talk

Hoskan, Mehmet Ali

Serotonin and indole sensing in the regulation of enterohemorrhagic E. coli (EHEC) pathogenesis

poster

Hryckowian, Andrew J

A butyrate-centric view of Clostridioides difficile pathogenesis

poster

Hsin, Fu

IFN-stimulated long non-coding RNAs enhance type I IFN induction by priming MDA5 activation

poster

Iliev, Asparouh I

Endocytosis boost by the cholesterol-dependent cytolysin pneumolysin enhances inflammatory response

poster

Iliev, Iliyan

Fungal contribution to host immune regulation

talk

Isberg, Ralph

Evolutionarily conserved strategies for attacking replication vacuoles and the pathogen counterattack

talk

Iwadate, Yumi D

Excess cation stress and tolerance mechanisms in Salmonella

poster

Jacobs-Wagner, Christine

Peptidoglycan shedding and immune response

talk

Jaishankar, Jananee

Membrane remodeling contributes to intracellular survival of Vibrio parahaemolyticus

poster

Jaisinghani, Neetika

Compartment specific cell wall labeling in mycobacteria used to identify cell wall proteins informs hierarchical secretion mechanism in type VII secretion systems

poster

Jensen, Grant

Electron cryotomography structure of the bacterial type IV secretion system

talk

Jimenez, Giselle

Investigating the phenotypic effects of BvaP, a novel membrane-bound and secreted protein conserved in Streptococcus agalactiae

poster

Jobson, Mary-Elizabeth

SSR42 is a regulatory RNA that governs proteolysis, hemolysis and cytolysis in Staphylococcus aureus

poster

Jones, Katerina M

Salmonella enterica serovar Typhimurium metabolizes Bacteroides-derived propionate to modulate intestinal invasion and overcome colonization resistance

poster

Jonna, Rachana

Bioinformatics based structural and functional characterization of TonB-dependent transport system in gut microbiota

poster

Joshi, Meenakshi B

A search for secreted effectors produced by the fungal meningitis pathogen Cryptococcus neoformans

poster

Kakade, Pallavi

Tuning of gene dosage in Candida albicans aneuploid cells regulates the yeast-hyphal transition and gut commensalism

poster

Kashiwagi, Saori

Mucus digesting Ruminococcus gnavus enhance adherent-invasive E. coli growth and H₂S to promote AIEC virulence and host responses

talk

Keestra-Gounder, Marijke

Nitrate-mediated luminal expansion of Salmonella Typhimurium is dependent on CHOP

poster

Kelliher, Jessica L

GpsB control of PASTA kinase activity in Listeria monocytogenes influences peptidoglycan synthesis during cell wall stress and cytosolic survival

poster

Keogh, Rebecca

Group B Streptococcus exploits the diabetic wound environment to subvert neutrophil killing and promote persistence

poster

Khosravi, Arya

Pseudomonas aeruginosa partners with a bacteriophage to acquire iron

poster

Kim, Youlim

Harnessing human gastroids to investigate Helicobacter pylori infection across the gastric gland

poster

Kimmey, Jacqueline M

Circadian control of pulmonary response and susceptibility to Streptococcus pneumoniae

talk

King, Ainsley E

The impact of two cell wall proteins, Fgr41 and Eng1, on cell wall organization in Candida albicans

poster

Koff, Jon

Personalized inhaled bacteriophage therapy decreases lung inflammation in cystic fibrosis

poster

Koleske, Benjamin

Screening the PE/PPE secreted effectors of Mycobacterium tuberculosis to uncover novel virulence-promoting genes

poster

Kulczyk, Arek

Cryo-EM structure of Shiga toxin 2 bound to the native ribosomal P-stalk reveals residues involved in the binding interaction and the intrinsic dynamics of complex formation

poster

Kumar, Aman

Impacts of medical drugs on the gut microbiome and colonization resistance

poster

Kumari, Sujata

Characterization of Negevirus envelope proteins and their functional role during entry into mosquito host cells

poster

Kutsch, Miriam

Stick it together—How GBPs activate the non-canonical inflammasome

poster

Lamason, Rebecca

Selective enrichment of secreted effectors during infection yields a putative inhibitor of the Sec61 complex

talk

Lanser, Dylan M

Applying a 3D blood-brain barrier organoid model to investigate dissemination of Cryptococcus neoformans to the central nervous system

poster

Laschanzky, Katie M

Phenotypic and genetic characterization of a virulent Mycobacterium avium ssp. hominissuis respiratory isolate from an immunocompetent individual in Malmö, Sweden

poster

Laurent, Audrey

Deciphering the initial response of endothelial cells to Neisseria meningitidis adhesion

poster

Leddy, Owen

pathMS—A mass spectrometry workflow to selectively identify pathogen-derived peptides in mixed host-pathogen proteomic samples

poster

Lee, Sohyoung

PltA regulates the export of typhoid toxin vesicle carriers by coopting the coat protein complex II

poster

Lee, Sungwon

Human cytomegalovirus long non-coding RNA4.9 restricts cGAS activity for immune evasion

poster

Lele, Pushkar

Energy-based segregation and visualization of tolerant bacteria and neutrophil interactions in confining environments

poster

Leonard, Allison

Exogenous fatty acids inhibit Staphylococcus aureus adhesion to host ligands

poster

Levitz, Stuart

Perfecting the recipe for a subunit Cryptococcus vaccine—You put the antigens in the adjuvant

talk

Li, Kexin

The role of the human gut microbiome in clinical sepsis

poster

Liao, Chen

The relative enrichment of oral bacteria in feces indicates a depleted gut microbiota with implications for human health

poster

Lionakis, Michail

IFN-γ/STAT1-mediated immunopathology drives epithelial barrier disruption and oral mucosal candidiasis

talk

Liu, Yichao

Prophyromonas gingivalis does it different—β-structure assembly in the inner membrane and links to outer membrane vesicle production

poster

Lokken-Toyli, Kristen L

Age-dependent mechanisms driving pneumococcal dissemination from the upper respiratory tract

poster

Ma, Peijun

Understanding the evolution of antibiotic resistance and persistence using bacterial single-cell RNA sequencing

poster

Madduri, Bala

Characterizing how Mycobacterium tuberculosis secreted effector proteins PE25 and PPE41 disrupt macrophage cell biology

poster

Marzook, Bishara

A microscopy-based arrayed CRISPR screen reveals the essential host genome for growth and development of intestinal parasite Cryptosporidium

poster

McFadden, Michael J

Activation of IRE1α during Candida albicans infection enhances macrophage fungicidal activity

talk

McKay, Liliana S

Three cytochrome oxidases are required by classical Bordetella species during mammalian respiratory infection

poster

McKenna, Joy A

Dissecting early molecular interactions between typhoidal and non-typhoidal Salmonella with human intestinal cells

poster

McLeish, Jemma D

Characterizing the role of the putative phosphatidylserine synthase in the pathogenicity of Candida glabrata (Nakaseomyces glabrata)

poster

Mejia, Marlyd

The host vaginal immune response to pathogen challenge and the contribution of the endogenous vaginal microbiota

talk

Mercado, Vicki

Gestational diabetes augments group B Streptococcus perinatal infection through disruptions in maternal immunity and the vaginal microbiota

poster

Meyer, Christian T

High throughput viability assay for microbiology

poster

Mike, Laura A

Klebsiella pneumoniae regulates capsular polysaccharide chain length and attachment in response to host cues

poster

Mills, Kathleen

Epithelial-immune cell crosstalk orchestrates pulmonary immunity to Aspergillus fumigatus

talk

Monteith, Andrew J

Neutrophil mitochondria sense intracellular bacterial metabolic activity and drive NET formation.

poster

Montoya-Giraldo, Manuela

Genomic and ecological contributions to the diversity of Streptomyces bacteria in bats

poster

Moreau, Christian T

Defining the genetic mechanisms of a dissemination prone morphotype of Cryptococcus neoformans

poster

Mortzfeld, Benedikt M

Microcin MccI47 selectively inhibits enteric bacteria and reduces carbapenem-resistant Klebsiella pneumoniae colonization in vivo when administered via an engineered live biotherapeutic

poster

Mothes, Walther

Viral spike–receptor interactions monitored by cryo-electron tomography on membranes

talk

Mukherjee, Shaeri

A Legionella toxin exhibits tRNA mimicry and glycosyl transferase activity to target the translation machinery and trigger a ribotoxic stress response

talk

Muramatsu, Matthew K

How Yersinia enterocolitica overcomes propionate mediated colonization resistance

poster

Nabukhotna, Kateryna

Clostridioides difficile transferase toxin activates the NLRP3 inflammasome

poster

Nair, Tripti

Pathogen apathy resulting from SKN-1 activation—A mark of resilience or a rattled gut feeling?

poster

Naqvi, Kubra F

Hypervirulent mycobacterium tuberculosis glycolipid activates lung innervating nociceptive neurons

poster

Nekrutenko, Anton

A globally accessibly free infrastructure for analysis of microbial genomic data

poster

Nelson, Eric J

Phage predation and antibiotic exposure are inversely associated with disease severity and shape pathogen genetic diversity in cholera patients

poster

Newson, Joshua P

Antibiotic-persistent reservoirs of Salmonella are determined by bacterial secretion machinery in vivo

poster

Nilsson, Olof R

Impacts on the central nervous system in Salmonella Typhimurium infected mice

poster

Nisbett, Lisa-Marie P

Exploring the mechanism of lipid transport to the outer membrane of mycobacteria in the LprG-Rv1410c pathway

poster

Nobs, Esther

Cytosolic serpins regulate host cell death and mycobacterial growth in vivo

talk

Nock, Adam

RoaM is a transcriptional regulator in Rickettsia rickettsii governing the transition to a cellular program of active spreading.

poster

Ochoa-Raya, Andrea

Elucidating the role of the Listeria monocytogenes virulence factor InlB during infection of human placental trophoblasts

poster

O'Meara, Teresa

Candida auris controls colonization and pathogenesis through the novel adhesin SCF1

talk

O'Rourke, Emily A

Inflammatory caspases and downstream host factors control vacuolar and cytosolic Salmonella replication in human macrophages

poster

Orth, Kim

Vibrio parahaemolyticus—Invasion, proliferation, and escape

talk

Paduthol, Gauri

Dissecting recurrent UTIs using a 3D human mini bladder microtissue model

poster

Palmer, Catherine S

Time of day impact on pneumococcal pneumonia

poster

Palmer, Lauren D

Genetic redundancy uncovers a role for ornithine catabolism in Acinetobacter baumannii gut colonization

poster

Parada-Kusz, Margarita

Tryptophan catabolism modulates the host response to bacterial infections via kainate-sensitive glutamate receptors

talk

Parente de Carvalho, Thaynara

Pericytes modulate endothelial inflammatory response during bacterial infection

poster

Park, Hankum

Exploring microbial virulence factors found in Alzheimer's disease brains using mass spectrometry

poster

Patras, Katy

An in vivo model of urinary tract infection-associated preterm birth

poster

Paulini, Kayla

Investigating the role of PRLs and CNNM in Leishmania donovani

poster

Pei, Jessica

Investigating the impact of Parkinson’s disease genes on intestinal homeostasis and infection

poster

Penaranda, Cristina

Analysis of Pseudomonas aeruginosa isolates reveals genetic and phenotypic diversity within the population that spans clinical and environmental isolation sites

poster

Peng, Wei

Investigation of the biochemical activity of a bacterial effector with Fido domain

poster

Perera, Dilhan J

A vaccine for intestinal schistosomiasis using an adenoviral vector expressing Schistosoma mansoni cathepsin B and adjuvanted protein boosts

poster

Perez-Orozco, Sebastian J

Systematic analysis of Enterobacteriaceae amino acid metabolism during colitis and ileitis

poster

Pfister, Milan

Population genomics of methicillin-resistant Staphylococcus aureus from bacteremia across five states in the United States

poster

Pickrum, Adam M

Identification of virulence mechanisms utilized by hospital-associated Staphylococcus aureus

poster

Piper, Kathryn

The diversification of the accessory genome of Staphylococcus aureus

poster

Post, Sarah

High throughput discovery of protein-mediated interactions between host and microbiota with functional metagenomic surface display

poster

Prasanphanich, Nina S

Decidual natural killer cells use granulysin to control placental infection

poster

Rahlwes, Kathryn C

Regulation of host immunity to Mycobacterium tuberculosis infection by deubiquitinases

poster

Ramstrom, Olof

Antivirulence approaches to antimicrobial action against P. aeruginosa

poster

Ravishankar, Sumedha

Visualization of vascular thrombosis and blood-brain barrier endothelial injury in a zebrafish larval model of Group B Streptococcal meningitis

poster

Reinke, Aaron W

The native Caenorhabditis elegans microbiome influences microsporidia infection through nutrient limitation and inhibiting parasite invasion

talk

Reyes Ruiz, Valeria M

Exploiting S. aureus TCS signaling to identify antibacterial effectors of the macrophage

poster

Reynolds, Mack B

Type I interferon remodels macrophage respiratory metabolism to dampen inflammatory signaling during Staphylococcus aureus infection

poster

Roberts, Cameron S

The protein targeting GlyGly-Cterm domain functions as a zip code to direct passenger enzymes to the cell surface

poster

Rojas, Vivian K

Gene regulation of tartrate metabolism in Salmonella Typhimurium

talk

Rolland, Steven J

PIK3C3 promotes Shigella flexneri spread from cell to cell

poster

Rosch, Jason W

Streptococcus pneumoniae favors tolerance via metabolic adaptation over resistance to circumvent fluoroquinolones

poster

Roy, Sayantan

Structural and biochemical characterization of an interferon-inducible GTPase, human guanylate binding protein 2 (GBP2)

poster

Russo, Brian C

Synaptopodin is necessary for Shigella flexneri intercellular spread

poster

Salisbury, Stephen

Hyperactive behavior—Virulence-associated rmp genes in classical Klebsiella pneumoniae

poster

Samuels, Veneshley

Advancing the single-cell biology captured from organisms in bioaerosols.

poster

Santiago-Tirado, Felipe H

Dissecting the mechanisms used by C. albicans to cause catheter-associated urinary tract infections (CAUTI)

poster

Santra, Shweta

Manipulation of toxin expression by Streptococcus pneumoniae for prolonged intracellular persistence

poster

Sawant, Namrata V

Mechanisms of LL-37 resistance in Uropathogenic E. coli strains isolated from postmenopausal women with recurrent urinary tract infection

poster

Scano, Colin

Production of microbial indole variants from clinical isolates of F. nucleatum and impact on host cell invasion

poster

Schade, Ruth A

Characterizing human macrophages as a niche for intracellular Salmonella enterica serovar Typhi replication

poster

Schwardt, Nicole H

Investigating Listeria monocytogenes colonization of the mammalian gallbladder

poster

Scindia, Yogesh

Hepcidin deficiency exacerbates candida albicans induced pyelonephritis

poster

Scobell, Sophia B

Evaluating the theoretical host range of poxviruses with a yeast growth assay

poster

Scott, Madeleine

Characterizing regulation of a Y. pestis T6SS by the translational GTPase BipA

poster

Segre, Julie

Genomic tracking of Candida auris an emerging fungal pathogen

talk

Serapio Palacios, Antonio

Unraveling host-pathogen protein-protein interactions during enteropathogenic Escherichia coli infection

talk

Shabnam, Shabnam

A novel amino acid transporter is required for fitness of Streptococcus pneumoniae

poster

Shaffer, Carrie L

Nanomachine mosaicism enables Helicobacter pylori trans-kingdom conjugation

talk

Shan, Liang

The CARD8 inflammasome dictates HIV and SIV pathogenesis and disease progression

poster

Shapiro, Rebecca

CRISPR-based functional genomic tools and applications to understanding antifungal resistance and fungal virulence

talk

She, Qianxuan

Phylogenomic analysis of colonizing and invasive Staphylococcus aureus in a neonatal intensive care unit reveals high levels of transmission of invasive strains

poster

Shea, Allyson

Uncovering the interplay between patient variables and uropathogen biology

poster

Shealy, Nicolas G

Diet-driven distinct amino acid profile drives susceptibility to S. Tm gastroenteritis

poster

Sheikh, Alaullah

Enterotoxigenic E. coli toxins impair normal intestinal epithelial cell maturation

talk

Silverman, Gregg

Longitudinal gut microbiota analyses and blooms of pathogenic strains during lupus disease flares

poster

Souza, Stephanie

Distribution and evolution of Panton Valentine Leucocidin (PVL) operon in Staphylococcus aureus

poster

Spaan, András

Human OTULIN haploinsufficiency impairs cell-intrinsic immunity to staphylococcal α-toxin

talk

Stocks, Claudia J

Enterococcus faecalis exploit neutrophils as an intracellular niche for replication and persistence

poster

Strzelec, Karolina

New variants of the ppad gene from P. gingivalis—An association with PPAD enzymatic function and clinical condition of periodontium in chronic periodontitis

poster

Stuckey, Peter V

Interferon-γ influences the outcome of fungal intracellular infection by promoting maturation of the cryptococcal-containing phagosome

poster

Sturd, Natalie A

Molecular analysis of the LRRF1-FLI1-CT226 complex reveals multiple potential mechanisms of Flightless 1 recruitment to the chlamydial inclusion membrane

poster

Sung, Jacqueline

Investigating the immunomodulatory role of epithelial YAP/TAZ during Helicobacter pylori infection

poster

Tan, Shumin

Illuminating Mycobacterium tuberculosis environmental cue integration and its coordination with bacterial metabolism during infection

poster

Tan, Sze Yin

Monitoring prion-like pathogens in the gut-brain axis with genetically encoded biosensors

poster

Tandon, Naman

Effect of O₂ availability in growth cultures on Salmonella phenotype and virulence.

poster

Taylor, Jaylen E

Bile inhibits bacterial toxin activity by instigating structural destabilization and oxidation

poster

Thaden, Joshua T

A second type III secretion system in Escherichia coli is associated with patient mortality in bloodstream infections

poster

Thomsen, Line

Streptococcus agalactiae persister cells

poster

Thornton, Justin A

Development of pneumolysin-neutralizing vaccine inducing mucosal immunity for protection against invasive pneumococcal disease

poster

Thurston, Teresa

Bacterial effectors and their many ways to interfere with host cell signaling

talk

Tiwari, Suman

Novel biofilm mutations promote minocycline resistance in Acinetobacter baumannii

poster

Tolbert, Jessica D

Structural and functional analysis of enteropathogenic virulence regulators—The first steps toward inhibitory mimetics

poster

Tran, Phuong

Aldehyde resistance in Mycobacterium tuberculosis

poster

Turcotte, Elizabeth

Species-specific antagonism of the human NAIP–NLRC4 inflammasome by Shigella flexneri

poster

Uchil, Pooja

Host factors engaged in the repair of the Mtb phagosome membrane

poster

Van Hoek, Monique

Quorum sensing—Francisella increases chitinase and siderophore production and decreases biofilm and pathogenicity island expression in response to the diffusible signal factor cis-2-dodecenoic acid

poster

Van Opijnen, Tim

Multidimensional host-bacterium profiles to help design new antimicrobial strategies

talk

Vance, Russell E

Early cellular mechanisms of type I interferon-driven susceptibility to tuberculosis

talk

Walch, Philipp D

Dissecting the impact of enteric viral-bacterial co-infection on the host innate immune response and its implications for pathogenicity

poster

Walker, Kimberly

Contribution of rmpC in Klebsiella hypervirulence—More than just capsule?

poster

Walsh, Dana M

The influence of birth mode and feeding method on the infant gut microbiome, mycobiome, and resistome in the first 21 days of life

poster

Walters-Marrah, George A

Deciphering host-pathogen metabolic interactions using an interdisciplinary approach

poster

Wang, Leyao

A natural disaster may alter the human microbiome in early life—Maternal exposure to hurricane Maria and the offspring’s gut and nasal microbiome

poster

Wheeler, Robert

Trojan horses, zombie fish and mechanisms of fungal dissemination

talk

White, Maxwell T

A procarcinogenic bacterial metalloprotease binds claudin-4 to mediate toxicity on the colonic epithelium

poster

Wilburn, Kaley M

Modeling disease tolerance during Mycobacterium tuberculosis infection using collaborative cross mice

poster

Winski, Christopher J

In vivo characterization and clinical implications of the ABC transporter PDR6, and other half-size transporters, in the pathogenic fungus Cryptococcus neoformans

poster

Wongdontree, Paprapach

The strategy of Staphylococcus aureus bypass FASII inhibitors and consequences for infection

poster

Xiao, Xieyue

Co-existence of a highly diverse set of Prevotella copri in a single human host

poster

Xu, Dijin

PLSCR1 is a cell-autonomous defense factor against SARS-CoV-2 infection

poster

Xu, Linlin

Metabolic and lipidomic dysregulation are hallmarks of postoperative infection, including sepsis, and are evident in preoperative data

poster

Yaqub, Muneer

Redefining antibiotic resistance in Acinetobacter baumannii

poster

Yasuma-Mitobe, Keiko

Microbiota-produced short-chain fatty acids impair Candida parapsilosis intestinal expansion by mediating intracellular acidification

talk

Zafar, M. Ammar

The gut battle—How Klebsiella pneumoniae deploys the type VI secretion system to overcome microbiota mediated colonization resistance

poster

Zaman, Anika

Protection from bloodstream Staphylococcus aureus infection by inactivation of the Sts phosphatases

poster

Zangara, Megan T

Psychological stress impairs mucosal gut barrier integrity and innate defense pathways leading to loss of host control of Crohn’s disease-associated adherent-invasive E. coli

poster

Zeng, Wenjie

Inactivation of host small GTPases by a Legionella lysine fatty-acyltransferase

poster

Zhai, Bing

Echinocandin heteroresistance causes prophylaxis failure and facilitates breakthrough Candida parapsilosis infection

poster

Zhang, Tianqi

Visualization and quantification of uropathogenic Escherichia coli biofilm development in vitro with Optotracing technology

poster

Zimnicka, Adriana

Listeria monocytogenes overcomes hemin toxicity to acquire iron to support bacterial growth.

poster

Zou, Angela

Differential gene regulation in Vibrio parahaemolyticus in response to bile acids

poster

Zychlinsky, Arturo

Neutrophil extracellular traps—The immune function of chromatin

talk