Glia in Health & Disease
July 21 - 25, 2016

You must register for the meeting in order to submit abstracts.
After registering you will be sent a web link for abstract submission by email.

Program information: An electronic version of the program abstract book will be sent three working days prior to the first day of the meeting, and hard copies will be available for collection upon your arrival at Cold Spring Harbor Laboratory. First night and keynote speakers are informed of their session date and time, otherwise program information is only available upon release of the electronic version of the abstract book. The reason we do this is to try and maximize interactions by encouraging participants to stay for the duration of the meeting.

Please check your email for talk length, poster instructions, and how to have your poster printed at CSHL for collection upon arrival. 

Abstract Status

Presenting Author

Abstract Title

Talk/Poster

Aber, E.

Macroautophagy in oligodendrocytes

poster

Allen, N.J.

Astrocyte regulation of neuronal glutamate receptors

talk

Arac, D.

Structural basis for regulation of oligodendrocyte development by GPR56

poster

Babetto, E.

Exploring a non-cell autonomous role of Phr1 for axon protection in mice

talk

Baldwin, K.T.

A candidate screen to identify novel regulators of astrocyte development and astrocyte-synapse interaction

poster

Barton, E.A.

Morphological analysis of microglia in the medial prefrontal cortex following binge alcohol consumption and exercise

poster

Behar, O.

Sema4B role in astrogliosis and neuronal survival during brain injury

poster

Beirowski, B.

Tak1 deletion in Schwann cells aggravates nerve pathology in LKB1-SCKO mice

poster

Benediktsson, A.M.

Examining the sub-cellular distribution of Glt-1, Kir 4.1 and mGluR5 within complex three-dimensional astrocytes in situ using DiOlistics

poster

Bennett, M.

New tools for studying microglia in the mouse and human CNS

poster

Bergles, D.E.

Context-dependent astrocyte dynamics visualized in freely moving mice

talk

Bijalwan, M.

The role of Nlrc5 gene in the development of Theiler’s virus-induced epilepsy

poster

Brophy, P.J.

Imaging of nodal protein transport and interactions

talk

Brown, I.

Regulation of the antioxidant glutathione by enteric glia during inflammation

poster

Burda, J.E.

Dissecting trauma-reactive astrogliosis in vivo by cell-type specific analysis of actively translating mRNA

poster

Carlsen, E.

Astrocytes enhance endocannabinoid-mediated modulation of synaptic transmission in networks responsible for movement production

poster

Casaccia, P.

Differential role of PRMT5 in oligodendrocyte progenitors and proneural glioma cells

poster

Chen, G.

Brain repair—Reversing glial scar through in vivo reprogramming

poster

Chen, M.

Nectin-like 2 (Necl-2) cell adhesion molecule is a negative regulator of Schwann cell myelination

poster

Chrast, R.

Distribution and function of monocarboxylate transporters in the peripheral nervous system

poster

Clarke, L.E.

Synapse pruning by astrocytes regulates hippocampal circuit development

poster

Cole, A.E.

Modulating bone morphogenetic protein signalling to promote oligodendrocyte maturation

poster

Coover, R.A.

Neuronal activity-dependent growth suppression underlies adult Schwann cell quiescence

poster

Corty, M.M.

Discoidin domain receptor promotes glial ensheathment of axons

talk

Coutinho-Budd, J.

The glial-secreted neurotrophin Spz3 promotes glial invasiveness and neuronal survival

talk

Cruz, E.A.

The role of glycogenolysis and astrocyte-neuronal lactate coupling mechanisms in memory formation during development

poster

Cunningham, R.L.

The guanine nucelotide exchange factor dock1 regulates Schwann cell development

talk

Daboussi, L.

Charcot-Marie-Tooth and lysosomal homeostasis

poster

Daneman, R.

Regulation of the blood-brain barrier in health and disease

talk

Das, G.

The tetraspanin CD82 regulates a reversible transition between OPCs and mature OLs

poster

De Biase, L.M.

Microglia in the basal ganglia exhibit distinct properties and functional states

poster

Delvalle-Dorta, N.M.

Tachykinin activation on enteric glia—A novel mechanism of enteric nervous system dysfunction in irritable bowel syndrome

talk

Deyneko, I.V.

Effects of a microtubule-destabilizing drug in CNS myelination

poster

Dimas, P.

Essential role of endogenous fatty acid synthesis in CNS myelin regeneration

poster

DiTullio, D.J.

A stroke-specific oligodendrocyte progenitor cell transcriptome reveals novel genes impacting recovery after white matter stroke

poster

Dornblut, C.

The myosin phosphatase inhibitor CPI-17 (ppp1r14a) induces cellular blebbing and is required for rapid CNS myelination and remyelination

poster

Elbaz, B.

Adenomatous polyposis coli regulates radial axonal sorting and myelination in the PNS

talk

Emery, B.

Pharmacogenetic stimulation of neuronal activity increases myelination in an axon-specific manner

talk

Escartin, C.

Specific inhibition of astrocyte reactivity reveals opposite roles in different mouse models of neurodegenerative diseases

talk

Estévez Povedano, R.

Astrocytic chloride channel activation defect in megalencephalic leukoencephalopathy

poster

Eyo, U.B.

Bi-directional microglial-neuronal interactions during glutamate-induced hyperactivity

talk

Farhy-Tselnicker, I.

The molecular mechanism of astrocyte secreted Glypican 4 in functional synapse formation

talk

Farmer, W.

Neurons diversify astrocytes in the adult brain through sonic hedgehog

poster

Fatima, M.

Novel molecular pathway of ATP release perturbed in astrocytes contributes to neuronal death in HIV-1 induced neurodegeneration

poster

Faust, T.E.

Astrocyte aldehyde dehydrogenase ALDH7A1 detoxifies the brain: metabolic impairment can disrupt higher brain function in neuropsychiatric disorders

poster

Feltri, L.

Yap and Taz are activated by mechanical signals in Schwann cells and control axon ensheathment and myelination.

talk

Fisher, E.S.

The role of glutamate uptake and metabolism in P2Y1R-enhanced neuroprotection after brain injury

poster

Fontenas, L.

Neuronal ndrg4 is essential for nodes of Ranvier organization in zebrafish

poster

Foo, L.C.

A role for mir-31a in astrogenesis in the adult brain; unveiling glial homeostasis in Drosophila melanogaster

poster

Fourgeaud, L.

Characterization of a novel TRPM2 antagonist, JNJ-28583113

poster

Frawley, L.

Regulation of glial cell size in the Drosophila peripheral nervous system

poster

Gao, V.

Astrocytic, not neuronal, β2-adrenergic receptors mediate hippocampal long-term memory formation in rats

poster

Garcia, R.I.

Robust and reliable Ca2 response to complex visual stimuli in astrocytic microdomains

poster

Gau, Y.A.

Imaging astrocyte calcium dynamics in the cerebral cortex of freely moving mice

poster

Gleichman, A.J.

Astrocyte heterogeneity after stroke—Differences within and between brain regions

poster

Glenn, T.

Gene expression analysis of spinal cord astrocytes during motor circuit development

poster

Gould, E.A.

Proteolipid protein null mice have unique behavior changes and altered numbers of oligodendrocytes

talk

Graham, L.C.

Diet-induced neuroinflammation causes white matter damage in aging and Alzheimer’s disease

poster

Granato, M.

A novel role for the low density lipoprotein like receptor Lrp4 in peripheral nerve regeneration

talk

Guilfoyle, E.M.

High expression of lipocalin 2 is cell autonomous in Alexander disease astrocytes

poster

Hasel, P.

Neurons and neuronal activity direct astrocytic gene expression and function

poster

Hawes, I.A.

Microglial colonization and interactions with synapses in the developing reward circuitry

poster

He, D.

Long non-coding RNAs in CNS myelination and remyelination

poster

He, X.

Olig2 progenitors and GNAS tumor suppressor in SHH-medulloblastoma

poster

Hippenmeyer, S.

Lgl1 controls neural stem cell lineage progression via intrinsic and cell-non-autonomous mechanisms

talk

Holmgren, T.N.

Myelination is critical for synaptic transmission in the deep cerebellar nuclei

poster

Hong, S.

Role of microglia in synaptic pathology in Alzheimer’s disease

talk

Johnson, K.M.

Microglia-dependent plasticity of  somatosensory circuits

poster

Kang, S.H.

Age-related changes in translational profile of oligodendrocytes

poster

Kanner, S.

Astrocyte replacement recovers neuronal synchronization in ATM-deficient cerebellar circuits in vitro.

poster

Karadeniz, Y.B.

Activity-dependent mechanisms regulating microglia-neural circuit interactions

poster

Katz, M.

Repetitive behavior and glutamatergic signaling are controlled by astrocyte-like glia in C. elegans

talk

Kautzman, A.G.

Sox2 deficiency leads to the abnormal development of retinal astrocytes in the mouse

poster

Kim, H.

Wnt/PCP pathway regulates myelination of the PNS

poster

Kim, J.

Oligodendroglial excitability mediated by glutamatergic inputs and Nav1.2 activation

poster

Kim, J.

Cell-competition mediates OPC transformation during gliomagenesis

talk

Klämbt, C.

Energy homeostasis in ensheathing glial cells modulates neuronal network function in Drosophila

talk

Kling, T.

Drosophila glia as mediator of axonal iron supply

talk

Koerber, I.

Gene-expression profiling suggests impaired signaling via the interferon pathway in Cstb-/- microglia

poster

Krencik, R.

Investigating human astrocyte function and complexity in development and disease

poster

Kucenas, S.C.

TNFa/TNFR2 signaling drives glial dynamics at the dorsal root entry zone

talk

Kurant, E.

Glial phagocytic receptors promote neuronal loss in adult Drosophila brain

talk

Lananna, B.V.

The astrocyte circadian clock regulates astrogliosis, neuroinflammation, and neuronal injury

poster

Langseth, A.

Decreased oligodendrocyte precursor cell proliferation and reduced oligodendrogenesis in Huntington’s disease

talk

Liddelow, S.A.

Activated microglia induce neurotoxic reactive astrocytes via Il-1α, TNFα, and C1q

talk

Liem, K.

Tubb4a and myelination in the mouse

poster

Lim, H.

Label-free imaging of Schwann cell myelination by third harmonic generation microscopy

poster

Lin, J.

The endocytic receptor LRP1 promotes oligodendrocyte progenitor maturation during development and injury induced white matter repair in adulthood

poster

Logan, M.A.

Transcriptional profiling of glial responses to axon injury in Drosophila

talk

Lopez-Anido, C.B.

Enhancer dynamics drive expression of peripheral myelin protein 22 in Schwann cells

poster

Lu, S.

Early B cell factor 1 and Regulator of G-protein signaling 5 are involved in the modulation of neuroinflammatory response

poster

Lu, T.

Open-source wearable miniature microscopes to study astrocytes and astrocyte-neuron interactions in freely behaving mice

talk

Lundgaard, I.

Glymphatic function is suppressed in the experimental autoimmune encephalomyelitis (EAE) model of multiple sclerosis

talk

Lyons, D.A.

How does neuronal activity regulate central nervous system myelination?

talk

Ma, Z.

Neuromodulators signal through astrocytes to alter neural circuit activity and behavior

talk

Mamiya, P.C.

Characterizing a possible role of oligodendrocyte dependent myelination in second language learning—A brain imaging study

poster

Marion, C.M.

Myelin plasticity supports recovery of nerve conduction velocity after experimental TBI

poster

Mattugini, N.

Influence of white matter injury on grey matter reactive gliosis upon stab wound injury in the murine cerebral cortex

poster

Maurel, P.

Nectin-like 4 (Necl4) cell adhesion molecule complexes with Choline Transporter-like protein-1 (CTL1) in Schwann cells to regulate choline transport, lipid biogenesis and myelination in vitro

poster

McGann, J.

Characterizing astrocyte transcriptional changes upon neuronal interaction

poster

Meireles de Sousa, A.M.

RNA localization in myelination

poster

Mironova, Y.A.

Myelinated fibers in the adult PNS and CNS differ in vulnerability to reduced levels of the signaling lipid PI(3,5)P2.

talk

Molofsky, A.

Astrocyte-microglial communication via innate immune molecules regulates developmental synapse pruning

talk

Mullin, A.

Hypoxia-ischemia alters the spatiotemporal dynamics of oligodendrocyte development and myelination in the neonatal rat brain

poster

Nari, J.M.

Regulation of vesicular trafficking events by myotubularin related protein 2 (MTMR2): Insights to loss-of-function mutations causing Charcot-Marie-Tooth disease

poster

Nguyen, A.Q.

The role of astrocytic ephrin-B1 in synaptogenesis, synaptic functions, and animal behaviors

poster

Nishiyama, A.

The role of histone methyltransferase Ezh2 in NG2 cell cycle regulation revealed by conditional knockout and single cell RNA-sequencing

poster

O'Koren, C.M.

The effect of pH and charybdotoxin on growth of human glioma cell lines

poster

Orr-Weaver, T.L.

The Drosophila blood-brain barrier and subperineurial glial cell size

talk

Panganiban, C.H.

Molecular and structural maturation of the nodes of Ranvier in mouse auditory nerve correlates with hearing onset

poster

Pasca, S.P.

Exploring human astrocyte development and maturation with a novel 3D culture system

poster

Patzig, J.

The impact of nuclear structure on oligodendrocyte development and pathology

poster

Paukert, M.

Impairment of astroglia calcium activation by ethanol and consequences for local circuit activity

talk

Peco, E.

Drosophila astrocytes—Insight into the astroglial map

talk

Petravicz, J.C.

Astrocyte glutamate transporters in visual cortex circuit function and plasticity

poster

Pham, J.T.

Pathology and functional implications of the C9orf72 repeat expansion in ALS/FTD iPS astrocytes

poster

Piao, X.

Microglia regulates oligodendrocyte development and CNS myelination through GPR56 signaling

talk

Poskanzer, K.E.

Astrocytes regulate cortical state switching

talk

Punal, V.M.

Mechanisms of astrocyte spatial patterning

poster

Rapti, G.

Glia and pioneer neurons direct hierarchical assembly of the C. elegans brain

talk

Rasmussen, J.

Bony scales organize cutaneous nerves in adult zebrafish

talk

Ray, A.

Extensive axonal damage is observed in Gas6-/-Axl-/- double-knockout (DKO) mice following chronic exposure to cuprizone

poster

Risher, M.

Protracted dysregulation of astrocyte synaptogenic factors after adolescent intermittent alcohol exposure

poster

Robel, S.

New roles for an old actor—Glial fibrillary acidic protein (GFAP) is protective in repeated traumatic brain injury

poster

Robinson, F.

Schwann cell-specific deletion of the endosomal phosphatidylinositol 3-kinase Vps34 leads to impaired radial sorting of axons and failed myelination

talk

Robitaille, R.

Differential regulation of synaptic strength of competing terminals by glial cells influence the outcome of synaptic competition at mammalian neuromuscular junctions

talk

Sakers, K.

Transcript-specific localized translation in peripheral astrocyte processes

poster

Samanta, J.

Modulation of remyelination by Gli1 and Gli2

talk

Sanchez, N.E.

The stl71 mutation causes decreased myelination in the peripheral nervous system

poster

Schacke, S.

Loss of the actin binding protein Ezrin results in reactive gliosis and beneficial stroke outcome

poster

Schafer, D.P.

Microglia-dependent regulation of neural circuit development and plasticity

talk

Scherer, S.S.

Ensheathment and support of neurons

talk

Schirmeier, S.

The Drosophila glia-neuron lactate shuttle

talk

Schnieder, T.P.

Contribution of CD163-positive macrophages to increased perivascular cell density observed in suicide

poster

Schulze-Steikow, M.

Expanding the oligodendrocyte population for brain regeneration in vivo

poster

Sherafat, M.

Differential proliferative response of white and gray matter NG2 cells to PDGF-AA is partly regulated by microglia Neuropilin-1

poster

Sherwood, M.W.

Astrocytic IP3 receptor type-1 regulates hippocampal LTP

talk

Shih, J.

Partial loss of GLAST leads to alterations in cortical network function and development

talk

Shivachar, A.C.

Microenvironmental cues signal morphological and molecular changes in astroglial cells in culture

poster

Simons, M.

Mechanisms of myelin turnover in the aging brain

talk

Singhvi, A.

A glial K/Cl channel regulates neuron receptive ending shape by chloride inhibition of a receptor guanylyl cyclase

poster

Sipe, G.O.

The role of astrocytic GABA transport in visual cortex

poster

Sofroniew, M.

Astrocyte functions after CNS damage and disease

talk

Sontheimer, H.W.

How malignant astrocytes highjack their surroundings

talk

Soto, I.

Neuroinflammatory responses precede loss of Purkinje neurons in the NPC1nmf164 mouse model of Niemann Pick Type-C disease

poster

Soung, A.

ADAMTS9 is a novel regulator of oligodendrocyte survival and myelination

talk

Stankovic, K.

Extracellular vesicles  derived from human vestibular schwannomas associated with poor hearing damage cochlear cells

poster

Stogsdill, J.A.

Astrocytic neuroligins control astrocyte development and synapse association

talk

Stork, W.T.

Genetic control of morphogenesis and function of astrocytes in Drosophila

poster

Sun, L.

Mosaic genetic analysis to investigate astrocyte development and function in vivo

poster

Sweeney, P.

Activation of hypothalamic astrocytes suppresses feeding without affecting anxiety-related behavior

poster

Tognatta, R.

Role of astrocytes in regulating CNS myelination, demyelination and early myelin repair in the vertebrate CNS

poster

Trotter, J.

Oligodendrocyte progenitor cells as players in the neuronal network via activity-mediated cleavage of the NG2 proteoglycan

talk

Ullian, E.M.

Investigating human astrocyte function and complexity in development and disease

talk

Vanderver, A.

TUBB4A-associated leukodystrophy is associated with mutation specific cell selective abnormalities

talk

Volkenhoff, A.

Nutrient homeostasis in the Drosophila nervous system

poster

Von Stetina, J.R.

Regulation of subperineurial glia cell size via the endocycle and endomitosis

poster

Voronova, A.

Forebrain interneuron-secreted signals regulate cortical precursor cell oligodendrogenesis

poster

Wallace, S.W.

PROS-1/Prospero is a major regulator of the glia-specific secretome controlling sensory-neuron shape and function in C. elegans

poster

Weinstock, N.I.

The contribution of Schwann cells and neurons to the pathogenesis of Krabbe disease

poster

Winkler, C.

Activation of a ventral pathway in dorsal forebrain progenitors initiates cortical oligodendrogenesis

poster

Wu, J.

Comprehensive identification of long non-coding RNAs in purified cell types from the brain reveals functional LncRNA in oligodendrocyte precursor cell fate determination

talk

Xin, W.

Functional and molecular profile of ventral midbrain astrocytes

poster

yang, H.

G protein-coupled receptor 37 is a negative regulator of oligodendrocyte differentiation and myelination

talk

Yang, Y.

Molecular specification of functionally heterogeneous dorsoventral and subcortical astrocyte sub-populations in adult central nervous system (CNS)

talk

Yao, C.

Oxidative stress impedes rhythmicity of central pattern generator and synaptic bouton formation of motor neurons in the Drosophila eaat1 mutant

poster

Yasumoto, Y.

Possible role of hypothalamic FABP7 in the control of glial cell proliferation and leptin sensitivity

poster

Yigit, H.

Activity-dependent local translation in NG2 cells as receivers and transducers of neuronal network signals

poster

Yu, G.

Automated functional analysis of astrocytes from chronic time-lapse calcium imaging data.

poster

Zhang, B.

What can neurons tell us about glia? Insights from forward genetic analysis of behaviors and circuits in fruit flies

poster

Zhang, L.

Hdac3 interaction with p300 histone acetyltransferase regulates the oligodendrocyte and astrocyte lineage fate switch

poster

Zhang, Y.

Purification and characterization of progenitor and mature human astrocytes reveals transcriptional and functional differences with mouse

poster

Zong, H.

Genetic tools to study in vivo glial biology

poster