Presenting Author

Abstract Title

Presentation

Abdulai-Saiku, Samira

The maternal X chromosome impairs cognition and accelerates brain aging through epigenetic modulation in female mice

poster

Acosta Rodriguez, Victoria A

Feeding time under caloric restriction modulates longevity in C57BL/6J male mice

talk

Allsopp, Richard

The FOXO3 longevity associated variant confers resilience to age-related diseases

poster

Alzate Correa, Diego F

Non-viral neurogenic and vasculogenic reprogramming of fibroblasts for the treatment of Alzheimer’s disease

poster

Anderson, Aaron A

Notch signaling in germline stem cells controls reproductive aging in C. elegans

poster

Anerillas, Carlos

YAP-TEAD supports senescent cell viability by lowering ER stress

poster

Armstrong, Joseph O

Using chemostats to explore the mechanisms of aging in yeast

poster

Aryee, Ebenezer

Metabolic diversity among dermal fibroblasts from regenerating and non-regenerating mammals

talk

Athar, Fathima

Understanding mechanisms of longevity and cancer resistance in bats

poster

Babcock, Kelsey

Linking impaired adult hippocampal neurogenesis in Alzheimer’s disease to defects in the quiescent neural stem cell pool

talk

Bai, Hua

Peroxisome-mitochondria communication in tissue aging

virtual poster

Basisty, Nathan

Discovery of senescent monocyte proteome and surfaceome biomarkers in humans

poster

Bedbrook, Claire N

Continuous behavioral tracking throughout lifespan predicts age and remaining life

talk

Benayoun, Berenice A

Sex-specific molecular and functional remodeling of aging murine macrophages

talk

Beydoun, Safa

The role of C. elegans fmo-1 in stress resistance and longevity

talk

Bhattrai, Janakraj

Investigating the role of HSF-1 in COMPASS complex-mediated lifespan extension

poster

Biashad, Ali

The brown seaweed Fucus Vesiculus (Fucoidan) activates SIRT6 and increases healthspan in mice

poster

Bieri, Gregor

Gnaq is a conserved neuronal regulator of cognitive rejuvenation in C. elegans and mice

poster

Bodnar, Andrea

Comparative genomics of sea urchins provides unique insights into extreme longevity and negligible aging

talk

Boos, Felix

Organ-specific regulation of protein homeostasis stress responses in vertebrate aging

poster

Britt, Raphael I

Expression and structural analysis of LINE1 proteins ORF1p and ORF2p

poster

Brown, Abigail

Multi-omics analysis reveals FOXO3 pioneer-factor activity in proliferating and senescent-like human cells

poster

Bulteau, Anne Laure

Reconstruction of RHE containing IPS-derived keratinocytes treated with mitochondrial stimulating plant extracts

poster

Burkewitz, Kristopher

ER calcium signaling coordinates mitochondrial dynamics and bioenergetics to promote longevity

talk

Byrns, China N

Senescent glia drive lipid storage in the aging Drosophila brain

poster

Caligiana, Alberto

Developing an in vitro model system to study LINE-1 retrotransposons

poster

Calvo-Rubio Barrera, Miguel C

Cytochrome b5 reductase-3 overexpression accelerates the onset of lipofuscin accumulation in male mice renal cortex

poster

Carapeto, Priscila

Exercise decreases pancreatic islet senescence through AMPK activation

talk

Carvajal Ibanez, Damian

Interferon regulates stem cell function at all ages by orchestrating mTOR and cell cycle

poster

Chakraborty, Tuhin S

The neuronal and molecular mechanisms by which death perception impacts fly behavior and lifespan

virtual poster

Chen, Chieh

Promoting longevity using endogenous metabolites

talk

Chen, Danica

Aging-associated Inflammation

talk

Chen, Jiangtian

Gut-derived neuropeptide F acts on multiple organs to regulate lifespan

talk

Cogliati, Tiziana

The Biological Resources Branch of the NIA—A one-stop source for aging research

talk

Cohen, Haim

Characterization of the SIRT6 dependent liver acetylome revealed its regulation of the healthy longevity mediator, H2S production

talk

Coig, Rene

A systems biology approach to understanding genetic heterogeneity in sex differences

poster

Colasanti, Jason

Investigating the role of miR-34a in choroidal neovascularization

poster

Coler-Reilly, Ariella L

Identifying drivers of aging among genes differentially expressed with age

poster

Cook, Stuart

The IL11/ERK/LKB1/AMPK/mTOR axis is a therapeutic target for extending mammalian healthspan

talk

Cooper, John P

Proteasome capacity changes during replicative aging

talk

Copp, Michaela E

SIRT6 activation in primary chondrocytes reduces the DNA damage burden from aging and osteoarthritis

poster

Cortassa, Sonia

In vivo metabolic fluxes along the circadian cycle of rats subjected to caloric restriction vs. ad libitum feeding

poster

Cote, Helene

A higher prevalence of chronic/latent viral infections among people living with and without HIV is associated with shorter leukocyte telomere length

poster

Crabbe Vert, Laure

Advanced human 3D-bioprinted skin constructs to model inflamm’aging

poster

Dalgarno, Audrey

A Hi-C map of the senescent genome at kilobase resolution reveals novel associations between architectural features and senescence-associated gene expression

poster

D'Amico, Davide

Urolithin A, a gut microbiome derived natural compound that activates mitophagy and improves muscle decline associated with aging

virtual poster

Das, Abhirup

TQS-168, a small molecule PGC-1α modulator, attenuates age-associated frailty, loss of endurance and inflammation

talk

Dinort, Eike

Deciphering the influence of the integrated stress response on cell health and resilience in C. elegans

poster

Dixon-McDougall, Thomas A

Generating novel therapeutics to rejuvenate senescent cells

poster

Du, Huixun

Substrate stiffness dictates unique doxorubicin-induced senescence-associated secretory phenotypes in primary pulmonary fibroblasts

poster

Dubal, Dena

X chromosome-derived mechanisms of sex differences in aging and neurodegenerative disease

talk

Easwaran, Sreesankar

Diapause—Can we “pause” and “play” reproductive development?

talk

Egan, Brian

acn-1, the nematode homolog of the angiotensin-converting enzyme, regulates aging in Caenorhabditis elegans

poster

Endicott, Joseph

Chaperone-mediated autophagy is required for metabolic reprogramming downstream of PTEN, a tumor suppressor and regulator of longevity

talk

Fernandez, Maria E

Long daily fasting periods promote greater geroprotection when combined with caloric restriction in female mice

poster

Galicia, Carlos

Analysis of long term clearance of p16 senescent cells during aging in mice

poster

Garrido, Amanda

Dietary intervention as a modulator of chemotherapy response

poster

Garrison, Jennifer L

Sex dimorphism in neural circuit for fluid homeostasis

talk

Gasperini, Caterina

Minding what we eat—The contribution of the gut microbiome to brain rejuvenation and aging

poster

Ghosh, Bhaswati

Tubular lysosome induction couples animal starvation to healthy aging

talk

Gigas, Jonathan

Phosphorylation of SIRT6 by AMPK in long-lived mammals—A link between two key regulators of aging

poster

Gilbert, Michael B

The neuropeptide neuroparsin-A regulates caretaking behavior in leafcutter ants

poster

Gillespie, Anna K

Hippocampal spatial representations as a potential biomarker for cognitive impairment in aging rats

poster

Giniger, Edward

Many typical features of aging fail to occur in animals raised without a bacterial microbiome

poster

Golestaneh, Nady

The anti-aging hormone Klotho promotes retinal pigment epithelial cell viability and metabolism by activating the AMPK/PGC-1α pathway

poster

Gonzalez Alvarez, Jose Carlos

Mechanisms behind TRF1 requirement for acquisition and maintenance of pluripotency

poster

Gonzalez, John T

Aging-invariant genes—Multi-tissue identification and characterization of murine housekeeping genes

poster

Gorbunova, Vera

Mechanisms of longevity and cancer resistance in long-lived mammals

talk

Goyal, Manu S

Brain metabolism and resilience in Alzheimer disease

poster

Griffin, Patrick T

TIME-Seq enables inexpensive and scalable epigenetic age predictions

talk

Guo, Longhua

Aging and regeneration in planarians and leopard geckos

talk

Hagiwara, Kenta

Aging enhances tissue remodeling-associated gene expression in macrophages

poster

Hahn, Oliver

A spatiotemporal map of the mouse central nervous system reveals white matter as a novel foci of brain aging

poster

Hajdarovic, Kaitlyn

Single cell analysis of the aging female hypothalamus

poster

Han, Jin

Age-associated senescent-T cell signaling promotes type 3 immunity that inhibits regenerative response

talk

Harel, Itamar

Sex-specific regulation of metabolic health and vertebrate lifespan by AMP biosynthesis

talk

Harrison, Ben

Insights into aging from a metabolome clock in the fruit fly

talk

Held, James P

Altered tRNA processing activates the mitochondrial unfolded protein response

poster

Henry, Evelynn

Identifying and characterizing a longevity control center in the Drosophila brain

poster

Henry, Samantha M

Aging and pregnancy induced development of the mammary gland

poster

Herman, Ali

Impairing senohemostasis by ablating DPP4 improves atherosclerosis

poster

Herzog, Chiara

Discordance in general and epithelial ageing signatures indicates hormone-mediated cancer risk

talk

Hillpot, Eric C

The 1.9 Å beaver Sirtuin6 crystal structure

poster

Holcom, Angelina

Expression of amyloid-beta and tau drives unique phenotypes in a co-expression C. elegans model of Alzheimer’s Disease

poster

Hoppe, Thorsten

Thermosensation is linked to ubiquitin-dependent protein turnover and aging via insulin and calcineurin signaling

talk

Horvath, Steve

Epigenetic predictors of maximum lifespan and other life history traits in mammals

talk

Hrvatin, Sinisa

Mouse model of inducible hibernation to examine the effects of hypothermic and hypometabolic states on aging

talk

Hsu, Hweijan

Piwi in the niche keeps germline stem cell young

virtual poster

Hubbard, E. Jane

Morphological mayhem in an aging stem cell niche

talk

Hussain, Mansoor

PARP1 regulates RECQL4 recruitment to double strand break site for efficient DNA repair

poster

Iouk, Tatiana

Yeast-longevity surrogates obtained in response to steroid lithocholic acid

poster

Ito, Naoki

Slc12a8 in the lateral hypothalamus as a key regulator of energy metabolism and skeletal muscle functions during aging

poster

Jakob, Ursula

ROS as early life modulators of lifespan and age-associated diseases

talk

Jang, Heeun

Age-related changes in the neural circuit for thirst behavior

poster

Jothi, Dhanalakshmi

Nit1 is a regulator of FoxO3a-dependent stress response

poster

Juarez Nunez, Karla A

Asymmetric protein inheritance in yeast replicative aging

talk

Juez, Oscar E

Conserved epigenetic mechanisms of aging in whole-plant senescence

poster

Kabir, Inamul

Age of the bone marrow dictates clonality of smooth muscle-derived cells in the atherosclerotic plaque

poster

Kaczanowski, Szymon

Experimental testing predictions of the endosymbiotic hypothesis of apoptosis origin

poster

Kalekar, Radha L

Mechanisms of transcriptional activation of LINE-1 elements during cellular senescence

poster

Kallijarvi, Jukka

Respiratory complex III deficiency drives c-MYC overexpression and illicit cell cycle entry leading to senescence and mitochondrial segmental progeria

talk

Kapahi, Pankaj

Glycation lowering combination therapy reduces caloric intake, improves glucose tolerance, and extends lifespan

talk

Karg, Margarete M

Partial in vivo epigenetic reprogramming improves age-associated retinal pigment epithelial cell dysfunction

talk

Karras, Georgios I

Illuminating HSP90’s selection shadow

poster

Katcher, Harold

Reversal of aging by factors present in young blood plasma

poster

Kedlian, Veronika

Human skeletal muscle ageing atlas

virtual talk

Kelsey, Maxfield

LINE-1—A sentinel detecting early cancer-associated epigenetic signatures?

poster

Kornfeld, Kerry

Notch signaling in germ line stem cells controls reproductive aging in C. elegans

talk

Korotkov, Anatoly A

Mechanisms of longevity in bats—DNA repair and cytoplasmic DNA sensing

poster

Kreiling, Jill A

An age-associated upregulation of the mir-465 family results in attenuation of growth hormone signaling

talk

Kuribayashi, Wakako

Role of Gadd45b in HSC aging

poster

Labunskyy, Vyacheslav

Targeting iron homeostasis to promote a longer lifespan

poster

Lananna, Brian V

eNAMPT-containing extracellular vesicles mitigate age-related cognitive decline

talk

Lapp, Samuel C

Mitochondrial plasticity permits intermittent fasting-mediated longevity by regulating substrate utilization

poster

Lee, Minseon

The role of SIRT6 in promoting epigenome stability and rejuvenation

poster

Lee, Patty J

Innate immune regulation of lung vascular senescence

poster

Lee, Yi-Tang

Mitochondrial GTP metabolism regulates reproductive aging through oocyte mitochondrial dynamics in Caenorhabditis elegans

talk

Lee, Young-Sam

Co-inhibition of ATM and ROCK synergistically improves cell proliferation in replicative senescence by activating FOXM1 and E2F1

poster

Legon, Luc H

The role of mTOR in neuronal transcription and neurodegeneration

poster

Lei, Hanyue

Reduced BDNF in the ventral tegmental area affects motivational behaviors in aged mice

poster

Leiser, Scott

Convergent pathways of environmental perception and longevity

poster

Lesnik, Chen

Enhanced BCAA metabolism improves age-related reproductive function

talk

Li, Hongjie

Aging Fly Cell Atlas

talk

Li, Zhiquan

Urolithin is a potent modulator of the cGAS-STING pathway

poster

Lin, Joseph B

Cell type-specific signaling between systemic immune system and choroid in age-related macular degeneration

poster

Lin, Yufei

The mir-465 family has higher expression with age in mouse liver and targets growth hormone signaling

poster

Linscott, Megan

RNA binding proteins—Regulation of miRNAs in the aging female brain

poster

Liu, Peiduo

mTORC2 protects the heart from high-fat diet-induced cardiomyopathy through mitochondrial fission in Drosophila

virtual poster

Liu, Yamin

Controlled delivery of anti-SASP ruxolitinib promotes aged bone healing by modulating macrophage M1 to M2 transition

poster

Llewellyn, Joseph

Evaluating the presence of senescence in induced neural stem cells derived from progressive multiple sclerosis patients

poster

Losick, Vicki P

Age-induced polyploidy remodels the actomyosin network altering epithelial mechanics over the fly’s lifespan

poster

Lu, Jinlong

Transposable elements-based methylation clock predicts chronological age and time to disease

poster

Lu, Yu-Xuan

Sexual identity of intestinal enterocytes regulates autophagy to determine intestinal health, lifespan, and the response to rapamycin

talk

Macoretta II, Nicholas J

The role histone modifications and variants in longevity of rodent species

talk

Madhavan, Sidharth S

Ketone bodies selectively insolubilize misfolded proteins in aging and Alzheimer disease

poster

Madsen, Helena

Comparing the mitophagy stimulators nicotinamide riboside and urolithin A

poster

Marino, Francesca

Female XX sex chromosomes and ovaries confer resilience to cognitive deficits in aging male and female mice

poster

Martinez, John C

Cytoplasmic LINE1s originate via the retrotransposition process and drive inflammaging

poster

Martinez-Delgado, David

Deciphering the impact of obesity on aging through RNA A-to-I modification

virtual poster

Maybury-Lewis, Sun Y

Tracking OSK reprogramming factors through rejuvenation of the aged epigenome

poster

Meadow, Michael E

Targeted proteomics to elucidate conserved mechanisms of SIRT6 regulation

poster

Miller, Karl N

A mitochondria-p53 pathway integrates DNA repair, genome stability, cytoplasmic chromatin, and the inflammatory phenotype of senescent cells

talk

Milman, Sofiya

Translational geroscience: Role of IGF-1 in human aging and longevity

talk

Minami, Satoshi

Cooperative action of p53 and autophagy delays kidney aging by suppressing DNA damage and the senescence-associated secretory phenotype

virtual poster

Mohd Rothi, Mohd Hafiz Bin

The 18S ribosomal RNA methyltransferase DIMT-1 regulates lifespan

talk

Moldakozhayev, Alibek

Essential roles of the thioredoxin systems in stress resistance and longevity

poster

Moqri, Mahdi

PRC2 clock—A universal epigenetic biomarker of aging and rejuvenation

poster

Moreira, Tiago

Uncovering the implications of obesity and ageing in cellular rejuvenation

virtual poster

Morrow, Chris

A role for molecular crowding in C. elegans aging

poster

Moses, Eitan

Signals from the reproductive system regulate vertebrate somatic regeneration

poster

Mosley, Matthew C

Aging fast and slow—What separates long- and short-lived individuals?

virtual poster

Nath, Ravi D

A genetic screen of vertebrate aging identifies new regulators of lifespan

talk

Neretti, Nicola

Single cell transcriptomics reveals global markers for different forms of cellular senescence.

talk

Ng, Bryan

Establishing fluid biomarkers associated with cellular senescence in Alzheimer’s disease

poster

Ngian, Zhen Kai

NELF-A dosage fine-tunes stress response genes to improve Drosophila healthspan and lifespan

poster

Nguyen, Eric H

3D-bioprinted outer blood retinal barrier model to characterize the role of senescent fibroblasts in dry age-related macular degeneration

poster

Oppezzo, Alessia

A novel approach to telomere-driven age-related diseases

talk

Pajuelo, Lourdes

CRTC-1 balances histone trimethylation and acetylation to promote longevity

poster

Papsdorf, Katharina

A lipid droplet-peroxisome network drives longevity by mono-unsaturated fatty acids by preventing lipid oxidation

talk

Park, Cana

Platelet factors are induced by longevity factor klotho and enhance cognition and its molecular signature in the aging hippocampus

poster

Park, Jaehyeon

DNA damage accumulation in cochlea cause early-onset hearing loss in mouse models of Alzheimer’s disease

poster

Park, Joong-Jean

Mitochondrial aconitase 1 regulates age-related memory impairment via autophagy/mitophagy-mediated neural plasticity in middle-aged flies

poster

Parkhitko, Andrey A

Targeting methionine metabolism late in life extends healthspan in both Drosophila and mice

poster

Partida-Aguilar, Maria

The aging metabolome of canine companions

poster

Patnaik, Praveen

Iron dyshomeostasis is one of the drivers of replicative aging in yeast

poster

Perez-Matos, Maria C

Pre-mRNA splicing regulation of lipid metabolism in longevity

poster

Petty, Christopher A

Ameliorating cellular senescence by partial epigenetic reprogramming

poster

Plesa, Alex

Transcriptomic reprogramming screen using functional RNA clock for cellular rejuvenation

talk

Pletcher, Scott

Modulation of Drosophila aging by nutrient demand and reward

talk

Poganik, Jesse

Biological age is increased by stress and restored upon recovery

poster

Pollina, Elizabeth A

An activity-dependent NPAS4 complex couples transcription to DNA repair to promote neuronal longevity

talk

Polymenis, Michael

Interventions of folate-based, one-carbon metabolic pathways—A conserved route to improved longevity?

poster

Postnikoff, Spike D

Autophagy is required for yeast replicative lifespan extension by interventions commonly used to extend metazoan lifespan

poster

Power, Lindsey N

Mapping DNA double strand breaks during replicative aging of Saccharomyces cerevisiae

poster

Prabhakar, Aditi

Defining physiological regulation of the mTORC1 pathway in aging

poster

Price, Nathan

Predicting mortality through analysis of metabolic rate in mice

poster

Remesal Gomez, Laura

Role of the iron associated protein FTL1 as a neuronal pro-aging factor promoting cognitive decline

poster

Rocha, Azucena

The role of nuclear cGAS in senescence entry and chromosomal stability

poster

Rogina, Blanka

The effects of shifting dietary calories on fly physiology and longevity

poster

Ruby, Graham

Insights into age-associated morbidity in mice from a home-cage, video ML-based frailty index

poster

Rudolph, Lenhard

Dietary vitamin-A depletion improves hepatic fat metabolism and skeletal muscle maintenance in aging mice

poster

Ruetz, Tyson

In vitro and in vivo CRISPR-Cas9 screens reveal drivers of aging in neural stem cells of the brain

talk

Russo, Maria

Senolytic activity of flavonoids in enhancing type-I and type-II cell death in human radioresistant cell lines

poster

Saeki, Marika

Ninjurin1 is involved in lysosomal damage response

poster

Salazar, Arnold M

Ageing promotes epithelial senescence and immune-senescence leading to pyroptotic cell death, tertiary lymphoid structure formation, and increased susceptibility to recurrent urinary tract infection (UTI)

virtual poster

Sanborn, Mark

Single-cell transcriptomic analysis identifies cell-type-specific gene expression signatures and dynamics of cellular senescence

poster

Santos Gil, Daniel F

Analysis of differential gene expression and intron retention in POLR3A-mutated Wiedemann-Rautenstrauch syndrome fibroblasts

virtual poster

Scharf, Andrea

Can Caenorhabditis elegans get old in a population?

poster

Schroer, Adam B

Young platelet factors attenuate inflammation and rescue cognition in aging

talk

Schwer, Bjoern

Role of DNA repair and Sirt6 in neuronal physiology

poster

Sebastiano, Vittorio

PRC2 clock—A universal epigenetic biomarker of aging and rejuvenation

talk

Seitz-Holland, Johanna

Relationship between biological senescence, physical, and mental health in late-life depression

poster

Seluanov, Andrei

Longevity and anticancer mechanisms in the longest-lived mammal the Bowhead whale

poster

Sharma, Arpit

Metabolic flexibility is modulated via remodeling of peroxisomal dynamics and metabolism

talk

Shaw, Cayce K

Aging awakens transcription of the inactive X chromosome (Xi) in cells of the female hippocampus

poster

Shea, Jeremy M

Microglia aging progresses through functional intermediate states

poster

Silva-Garcia, Carlos G

CRTC-1 balances histone trimethylation and acetylation to promote longevity

talk

Simon, Matthew A

A centenarian variant of SIRT6 enhances genome maintenance activity

talk

Simons, Mirre

Dietary restriction is evolutionary conserved in the Drosophila lineage on the phenotypic and transcriptome level

poster

Smith, Hannah J

Targeting a nutrient sensor in the neurons promotes longevity without fitness trade-offs in C. elegans

poster

Smith, Jeffrey S

Yeast chronological lifespan extension by isonicotinamide reveals links with nucleotide and one-carbon metabolism

poster

Stoeger, Thomas

Aging is associated with a systemic length-associated transcriptome imbalance

poster

Stroustrup, Nicholas E

Systematic mapping of organism-scale gene-regulatory networks in aging using population asynchrony

talk

Su, Cathy

Single cell RNA-Seq based aging clocks for human brain

poster

Tabata, Keisuke

ULK1 palmitoylation by ZDHHC13 is required for autophagy

poster

Takahashi, Takehiro

Transposable element LINE-1 activation in the cerebellum drives ataxia

poster

Tarkhov, Andrei E

Nature of epigenetic aging clocks from a single-cell perspective

poster

Tatar, Marc

An insulin/IGF receptor allomorph may extend Drosophila lifespan through methionine restriction

talk

Terao, Ryo

Dysregulated lipid metabolism and cellular senescence in age-related macular degeneration

poster

Terskikh, Alexey

Microscopic imaging of biological age

talk

Tian, Xiao

Epigenetic reprogramming reverses neuronal aging and improves cognitive performance

talk

Tokizane, Kyohei

The role of Ppp1r17 neurons in the dorsomedial hypothalamus in mammalian aging and longevity control

talk

Tombline, Gregory

Comparative proteomic and metabolomic analysis of plasma in mammals

poster

Tran, Khoa A

Function of PDHX in the metabolic-epigenetic axis of cellular senescence

poster

Tsai, Shihyin

Mass up aging skeletal muscle­ study of mTORC1 and sarcopenia

poster

Tuckowski, Angela

The role of fmo-4 in longevity and stress resistance

poster

Vaidya, Himani

DNA methylation entropy as a measure of stem cell aging

poster

Valera Alberni, Miriam

Calcineurin at the intersection between longevity and mitochondrial dynamics

poster

Varshavsky, Miri

Improved age prediction from blood using a small set of DNA methylation sites with a non-parametric cohort-based GPR model

poster

Verdesca, Andrew

Regeneration promotes longevity in the planarian Schmidtea mediterranea

poster

Vergani, Carlos

Increasing ALG-1 Levels promotes miRNA biogenesis and improves oxidative stress response in C. elegans

poster

Walker, Amy K

S-adenosylmethionine synthases specify distinct H3K4me3 populations and gene expression patterns during heat stress

talk

Wan, Mei

Oxylipin-PPARγ-INK signaling triggers bone marrow adipocyte senescence

poster

Wang, Helen H

Cellular rejuvenation for skin wound healing

virtual poster

Wang, Lu

Reconfiguration of three-dimensional enhancer connectome in senescence and aging

poster

Wang, Yucheng

Recalibrating the cerebellum DNA methylation clock—Implications for ageing rates comparison

virtual poster

Wester, Laura

Germline stem cell quiescence and re-activation during the adult reproductive diapause in Caenorhabditis elegans

poster

White, Jim

Multi-omic rejuvenation and lifespan extension upon exposure to youthful circulation

poster

Wong, Shiquan

Neuronal HLH-30/TFEB modulates peripheral mitochondrial fragmentation to improve thermoresistance in C. elegans

poster

Woo, Seung-Hwa

ANT2 accelerates cutaneous wound healing in aged skin via mitochondrial energy reprogramming

poster

Xu, Lucy

Partial reprogramming of the aging neurogenic niche as a potential rejuvenation strategy

talk

Yanagawa, Kyosuke

A novel role of Atg proteins in proteostasis

poster

Yanai, Hagai

Periodic restricted feeding in Rhesus macaques results in significant microbiome changes associated with weight loss and hematopoietic homeostasis

poster

Yang, Jae-Hyun

Loss of epigenetic information as a cause of mammalian aging

poster

Yang, Ming

Interpreting the asynchrony of senescence through cell population dynamics

poster

Yerevanian, Armen

Riboflavin depletion promotes longevity and metabolic hormesis in C. elegans

poster

Ying, Kejun

Identifying causal CpG Sites for lifespan and healthspan and construction of causality-informed epigenetic clocks

poster

Yoshimori, Tamotsu

Autophagy in aging

talk

Yu, Doudou

Trajectory inference and machine learning analysis of single-cell transcriptomics of the aging hypothalamus

poster

Zacher, Max E

Mechanisms of longevity and cancer resistance in the bowhead whale

poster

Zapata, Heidi J

Dectin-1 stimulation promotes a distinct inflammatory signature in the setting of HIV-infection and aging

poster

Zhang, Pingze

S6K regulates immune ageing and lifespan via the endolysosomal system

poster

Zhang, Zhihui

Overexpression of naked mole rat hyaluronan synthase 2 promotes longevity and enhances healthspan in mice

talk

Zhao, Kevin

TNF and age impair the ability of macrophages to kill Streptococcus pneumoniae

poster

Zhao, Xiaoai

Lipidomic profiling reveals age-dependent changes in complex plasma membrane lipids that drive neural stem cell aging

poster

Zheng, Minyan

PARP14 hydrolyses NAD+ during TLR-induced inflammation, coronavirus infection, and aging

poster

Zheng, Zhizhong

Evolution of high-molecular-mass hyaluronic acid is associated with subterranean lifestyle

poster

Zhou, Olivia

Chromatin accessibility dynamics of neurogenic niche cells reveal defects in neural stem cell adhesion and migration during aging

poster

Zibrova, Daria

Investigating the role of the hexosamine biosynthesis pathway in endothelial cell senescence

virtual poster