|
Presenting Author |
Abstract Title |
Talk/Poster |
|
Abadie, Kathleen V |
Early CD8 T cell fate programming revealed by time-resolved RNA sequencing and live imaging of single cells |
talk |
|
Abdalla, Nada M |
Transcriptional regulatory network in human innate lymphoid cells from scRNA-seq and scATAC-seq |
poster |
|
Achour, Achouak |
Age-related changes at chromatin and gene expression levels of naïve T cells |
poster |
|
Ackerman, Margie |
Principal components of antibody activity―High throughput humoral profiling and machine learning to advance vaccine research and development |
talk |
|
Aggarwal, Kunal |
Deciphering the critical determinants of CD4 T cell differentiation into helper and regulatory cell subtypes |
poster |
|
Alon, Uri |
Autoimmune disease as a fragility of immune surveillance against hypersecreting mutants |
talk |
|
Alpert, Ayelt |
High resolution comparison of cancer samples through trajectory alignment |
poster |
|
Andreatta, Massimo |
Projecting single-cell transcriptomics data onto a reference T cell atlas to interpret immune responses |
poster |
|
Apps, Richard |
Unsupervised dynamic pattern analysis reveals features of responses to adjuvant that overlap with baseline variation between individuals and predict vaccination titer |
poster |
|
Arulraj, Theinmozhi |
In silico analysis of germinal center shutdown |
poster |
|
Ashour, Diyaa |
Dissecting the interrelation between T-cell senescence and myocardial aging |
poster |
|
Atianand, Maninjay |
The role of long noncoding RNAs in gene regulation in human macrophages |
poster |
|
Baker, Gregory J |
CyLinter: Interactive software for cleaning microscopy-derived, single-cell data |
poster |
|
Bandyopadhyay, Arnab |
Modeling the germinal center reaction and the production of memory B and plasma cells |
poster |
|
Banerjee, Ushashi |
Genome-wide network analysis identifies key genes in maintenance of latent tuberculosis |
poster |
|
Barvalia, Maunish |
Using single cell technologies such as mass cytometry and single cell RNA sequencing to interrogate the role of LYN tyrosine kinase in monocytes |
poster |
|
Baugh, Lauren M |
Sex hormone-driven crosstalk between human endometrial cells and macrophages in a 3D in vitro model |
poster |
|
Baumjohann, Dirk |
Temporal dissection of the T cell-intrinsic factors that maintain T follicular helper cell identity and germinal centers |
poster |
|
Becker, Nils B |
Robust cytokine ligand discrimination by asymmetric receptor dimerization and turnover |
talk |
|
Benoist, Christophe |
A Cloud Atlas |
talk |
|
Benos, Takis |
Causal analysis on PBMC-derived gene expression data identifies predictive signature of vaccine response in two MUC1 preventative vaccine trials in patients with the history of advanced adenoma of the colon |
poster |
|
Bibby, Jack |
Using single cell pathway analysis (SCPA) to map transcriptional dynamics during early T cell activation |
poster |
|
Blish, Catherine |
Multi-omic profiling to understand COVID-19 immunopathogenesis in vivo and in vitro |
talk |
|
Boccuni, Laura |
Mechanism of cross-talk between p38 MAPK and Interferon signaling |
poster |
|
Boehm, Thomas |
Evolutionary novelties in vertebrate immune systems |
talk |
|
Brauns, Elisa |
Functional reprogramming of monocytes in acute and convalescents Covid-19 patients |
poster |
|
Briller, Mayan |
Longitudinal multi-omic characterization of SARS-COV-2- mRNA vaccine dynamics |
talk |
|
Brodin, Petter |
Bifidobacteria-mediated immune system imprinting early in life |
talk |
|
Bryson, Bryan |
Learning the language of viral evolution and escape |
talk |
|
Buckley, Katherine M |
Analysis of the system-wide immune response to dysbiosis in the gut of sea urchin larvae reveals both deep conservation and evolutionary novelty |
talk |
|
Bullock, Margaret Elise |
Modeling epigenetic regulation of transcriptional noise in response to TNF |
poster |
|
Burel, Julie G |
Systems immunology reveals HLA-DR is a marker for effector CD4 T cells in active tuberculosis patients |
poster |
|
Cameron, Cheryl M |
Transcriptomic profiles of response in two MUC1 preventative vaccine trials, a pilot study and a recently unblinded randomized, double-blind, placebo-controlled trial in patients with newly diagnosed advanced adenoma of the colon |
poster |
|
Carvalho, Klebea |
Uncovering the gene regulatory networks underlying macrophage polarization through comparative analysis of bulk and single-cell data |
poster |
|
Chakraborty, Arup |
How to hit highly mutable pathogens where it hurts |
talk |
|
Chaudhri, Virendra K |
Digital and fuzzy binary transcriptional elements are prevalent features of immune cis-regulomes |
poster |
|
Cheemalavagu, Neha |
Predicting cytokine-specific STAT regulation and inflammatory gene expression using computational modeling |
talk |
|
Chen, Sisi |
Probing the multicellular mechanisms of drug response in heterogeneous immune cell populations |
talk |
|
Cheung, Foo |
Gender and prior exposure shape innate immune responses to a replication-defective herpes virus vaccine |
poster |
|
Choi, Jaewoo |
The novel positive regulator of proximal B cell receptor signaling in B cell lymphomas |
poster |
|
Chopp, Laura B |
Leveraging single-cell genomics to build gene regulatory networks involved in ab T cell development |
poster |
|
Chowdhary, Kaitavjeet |
A tiered network of transcription factors shapes Treg diversity |
poster |
|
Cifello, Jeffrey |
Determining IAV M158-66-specific CD8+ TCRs based on αβ paired CDR1-3 amino acid sequences using machine learning |
talk |
|
Claringbould, Annique |
Validating cell-type-specific gene regulatory networks by predicting perturbation response |
poster |
|
Consiglio, Camila R |
Deciphering the roles of sex hormones in the human immune system |
poster |
|
Cooper, Martha M |
Predicting host control of parasite burden following controlled human malaria infection |
poster |
|
Covert, Markus |
Engineered fluorescent E. coli lysogens allow live-cell imaging of functional prophage induction triggered inside macrophages |
talk |
|
Cowan, Jennifer E |
Single cell approaches to unravel thymic epithelial cell heterogeneity and alterations with age |
poster |
|
Daga, Neha |
Understanding genetic and epigenetic T-cell regulatory mechanisms in autoimmune diseases |
poster |
|
Das, Jishnu |
CausER―A general approach to uncover latent causal factors from multi-omic immunological datasets |
talk |
|
Davalos, Oscar A |
Dynamic transcriptional profiling of CD8 T cells during early autoimmune disease |
poster |
|
Davies, James D |
Transcriptional programming of tolerogenic and immunogenic responses in human epidermis |
poster |
|
Davis, Mark |
Human lymphoid organoids for systems immunology |
talk |
|
Devlin, Joseph C |
Multimodal single cell sequencing of adaptive immune cell repertoires and transcriptomes in response to SARS-CoV-2 infection and vaccination |
poster |
|
Dongre, Anushka |
Carcinoma cell-intrinsic factors associated with the mesenchymal state drive resistance of breast carcinomas to immune checkpoint blockade therapy |
poster |
|
Doron, Itai |
Human gut mycobiota tunes immunity via CARD9-dependent induction of anti-fungal IgG antibodies. |
poster |
|
Dupic, Thomas |
Immune fingerprinting through repertoire similarity |
talk |
|
Espinoza, Diego A |
Single-cell RNA-seq of human tonsillar B cells reveals distinct activation and maturation states and provides insight into the transcriptional dynamics of the germinal center reaction |
poster |
|
Farmer, Rohit |
Stim cell selector―A high-dimensional approach for the identification and quantification of single-cell responses in stimulation-cytometry data |
poster |
|
Filip, Ioan |
HLA allele-specific expression loss in tumors can shorten survival and hinder immunotherapy |
poster |
|
Ford, Rhodes |
Epigenetic dysfunction of terminally exhausted tumor infiltrating T cells |
poster |
|
Fox-Fisher, Ilana |
Remote immune processes revealed by immune-derived circulating cell-free DNA |
talk |
|
Geddes-McAlister, Jennifer |
Combatting fungal diseases through the discovery and elucidation of novel anti-virulence strategies by quantitative proteomics |
poster |
|
Germain, Ronald |
How small variations in protein expression, cell state, and signaling responses impact immunity and affect interpretation of GWAS data |
talk |
|
Gfeller, David |
Prediction of neo-epitope immunogenicity reveals TCR recognition determinants and provides insight into immunoediting |
talk |
|
Gibbs, David L |
Patient-specific cell communication networks associate with disease progression in cancer |
poster |
|
Glass, Marla C |
High-dimensional single-cell profiling reveals the phenotypic diversity and clinical relevance of human regulatory B cells |
poster |
|
Han, Bing |
Acute exposure of hydrocortisone after induced pyroptosis triggers IL-1β release in THP-1 macrophages while maintaining cells´ viability |
poster |
|
He, Lian |
Engineered LOV2 as a modular photoswitch for optogenetic control of calcium signals and cell therapy |
talk |
|
Henrickson, Sarah E |
Obesity dysregulates immunometabolic status in pediatric asthma and impacts vaccine responses |
talk |
|
Hoffmann, Alexander |
In early B lymphopoiesis dynamic modulation of NFκB is required for the proper pacing of developmental transitions |
talk |
|
Holla, Prasida |
Shared transcriptional profiles of atypical B cells suggest common drivers of expansion and function in malaria, HIV and autoimmunity |
poster |
|
Hou, Wenpin |
A computational framework for differential pseudotime analysis across conditions within multiple single-cell RNA-seq samples reveals T cell immune dynamics associated with COVID-19 disease severity |
poster |
|
Hu, Sophia G |
Vector field analysis using Dynamo to study covid19 symptom severity and EMT |
poster |
|
Ji, Zhicheng |
Reconstruction of conserved immune landscape in COVID-19 patients via multi-study integrative analysis of single-cell RNA-sequencing data |
talk |
|
Jing, Ji |
Optogenetic control of non-apoptotic cell death |
poster |
|
Jolly, Adrien |
Quantifying thymocyte proliferation and differentiation with CycleFlow |
poster |
|
Katz, Samuel |
Differential isoform usage reveals a regulatory layer in the macrophage LPS response not evident from differential expression analysis |
poster |
|
Kavazovic, Inga |
Obesity-induced memory CD8 T cell dysfunction in mice is independent of direct insulin signaling |
poster |
|
Kelsey, Ilana |
Single-cell characterization of macrophage polarization plasticity and mechanisms of regulation |
poster |
|
Kim, Chae Won |
Single cell transcriptomic re-analysis of immune cells in bronchoalveolar lavage fluids reveals the correlation of B cell characteristics and disease severity of patients with SARS-CoV-2 infection |
poster |
|
Konda, Prathyusha |
Discovery of tumor-associated T cell epitopes through targeted searches of mass spectrometry data |
poster |
|
Krishnaswamy, Smita |
Multiscale PHATE exploration of SARS-CoV-2 data reveals multimodal signatures of disease |
talk |
|
Kueh, Hao Yuan |
Tunable, division-independent control of T cell lineage commitment timing by a polycomb switch |
poster |
|
Lacsina, Joshua R |
Defining human skin immunity to vector insect bites |
poster |
|
Lawton, Matthew L |
Phosphoproteomic analysis of T cell exhaustion program reveals actionable system levels changes in signaling pathways driving differentiation |
poster |
|
Lee, Jiyoung |
Single cell RNA-Seq and machine learning reveal novel subpopulations in low-grade inflammatory monocytes with unique regulatory circuits |
poster |
|
Lewis, Sloan A |
Integrative scRNA-Seq, epigenetic, and functional profiling of the myeloid compartment in non-human primates following chronic alcohol consumption |
poster |
|
Lim, Wendell |
Sensing and sensibility―Programming smarter CAR T cells |
talk |
|
Link, Verena M |
Highly controlled nutritional interventions uncover defined immune and microbiome responses in human. |
talk |
|
Liu, Can J |
Time-resolved multimodal single cell analyses of COVID-19 reveal disease severity network |
poster |
|
Liu, Chunhong |
A critical CTCF binding site of the Ifng-Il22 locus specifies and finetunes cytokine expression and immune response |
poster |
|
Liu, Shirley |
In vivo CRISPR screens identify E3 ligase Cop1 as a modulator of macrophage infiltration and cancer immunotherapy target |
poster |
|
Lu, Jian |
Analysis of the fine subpopulations of human CD8+ T cells and their changes with age by single cell RNA sequencing and multi-color flow cytometry |
poster |
|
Lu, Wen |
Acute Csk inhibition hinders B cell activation via constraining PI3 kinase pathway |
poster |
|
Ma, Guolin |
Identification of a STIM1 splicing variant that promotes glioblastoma cell growth |
poster |
|
Martins, Andrew J |
High-dimensional blood immune cell subset resolved transcriptional regulatory network changes in early life |
poster |
|
Matz, Hanover |
Evolutionary precursors of germinal centers are present in sharks |
poster |
|
McGinnis, Christopher S |
Single-cell epigenomics sample multiplexing using MULTI-ATAC-seq and applications to peripheral blood mononuclear cells |
talk |
|
McGrail, Daniel J |
One side does not fit all―Cancer type specificity of immune checkpoint blockade biomarkers |
poster |
|
Medzhitov, Ruslan |
Cell communication in tissue organization |
talk |
|
Mehta, Arnav |
Plasma proteomic biomarkers reveal biological insights about the tumor microenvironment in melanoma patients after PD1 blockade |
poster |
|
Meyer, Aaron S |
Developing a mechanistic view of mixed IgG antibody immune effector responses |
talk |
|
Milanez-Almeida, Pedro |
Integration of human and artificial intelligence in multi-modal single cell data analysis |
poster |
|
Miraldi, Emily R |
maxATAC―A suite of models for transcription factor binding prediction from (sc)ATAC-seq applied to human T-cell activation |
talk |
|
Miranda-Bedate, Alberto |
Innate immune transcriptional signature of human bronchiolar epithelial cells in response to B. pertussis |
poster |
|
Mistri, Somen K |
Single-cell proteogenomics reveals that SLAM/SAP signaling regulates the development of innate-like γδ T cell subsets with distinct TCR repertoires |
poster |
|
Miyazaki, Masaki |
The transcription factor E2A activates multiple enhancers that drive cell type-specific Rag1/Rag2 expression during T and B cell development |
poster |
|
Mule, Matthew P |
Pinpointing cell states associated with vaccination response with new computational tools for nested-group CITE-seq analysis |
talk |
|
Munoz-Rojas, Andres R |
Cell-to-cell interaction networks between regulatory T cells and mesenchymal stromal cells identify novel signaling pathways regulating muscle repair |
talk |
|
Netea, Mihai |
A systems immunology approach to understand trained immunity |
talk |
|
Nguyen, Nhung |
Nano-optogenetic immunoengineering: Photo-tunable remote control of CAR T-cells |
poster |
|
Nguyen, Trang T |
Cbl-b deficiency prevents functional but not phenotypic T cell anergy |
poster |
|
Nicotra, Matthew L |
In search of an invertebrate allorecognition signaling pathway |
poster |
|
Normand, Rachelly |
A single-cell and spatial atlas of autopsy tissues reveals pathology and cellular targets of SARS-CoV-2 |
talk |
|
Obradovic, Aleksandar |
Network-based single-cell protein activity identifies signature of renal tumor-specific macrophages predictive of post-surgical recurrence |
poster |
|
Ong, Irene |
The landscape of antibody binding in SARS-CoV-2 infection |
poster |
|
Orcutt-Jahns, Brian |
Structured decomposition maps the determinants of immune cell response to γ-chain cytokines at the population and single cell levels |
poster |
|
Osmanbeyoglu, Hatice U |
SPaRTAN, a computational framework for linking cell-surface receptors to transcriptional regulators |
poster |
|
Oyler-Yaniv, Jennifer |
TNF controls a speed-accuracy tradeoff in the cell death decision to restrict viral spread |
talk |
|
Pagadala, Meghana |
Common genetic variants influence the composition of the tumor immune microenvironment and host anti-tumor responses |
poster |
|
Park, Jang Hyun |
Hypoxia regulates γδ T cell-mediated antitumor immunity in the brain cancer |
poster |
|
Park, Kyemyung |
Quantitative dissection of immune homeostasis using multi-scale modeling approaches |
talk |
|
Pauken, Kristen E |
Use of single-cell analyses to characterize circulating anti-tumor CD8+ T cells in mice and humans and identify markers for their isolation |
poster |
|
Pease, Nicholas A |
The timing of Bcl11b activation regulates the balance in thymic ILC and T cell differentiation |
poster |
|
Pelka, Karin |
Multicellular immune hubs and their organization in MMRd and MMRp colorectal cancer |
talk |
|
Perelson, Alan |
Modeling acute viral infections with considerations of immune responses and viral antagonism |
talk |
|
Pham, Nhung |
WikiPathways as a platform for COVID-19 pathway models |
poster |
|
Phillips, Angela M |
Mapping the sequence-affinity landscape of broadly neutralizing anti-influenza antibodies |
talk |
|
Prigozhin, Daniil M |
A limited subset of plant immune receptors is responsible for the generation of new immune specificities |
talk |
|
Pulendran, Bali |
Systems biological analysis of immunity to infection and vaccination |
talk |
|
Pullen, Krista M |
Translation of vaccine immune response across studies via TransCompR |
poster |
|
Quake, Stephen |
Dissecting the human immune system with single cell transcriptomics |
talk |
|
Rachmaninofff, Nicholas A |
Immune variation from infancy to adolescence |
poster |
|
Ravichandran, Sathyabaarathi |
Identification of molecular subnetworks that can assess disease severity in COVID-19 patients |
poster |
|
Reddy, Sai T |
Convergent selection in antibody repertoires is revealed by deep learning |
talk |
|
Reyes, Miguel |
Induction of a regulatory myeloid program in bacterial sepsis and severe COVID-19 |
poster |
|
Robertson, Catherine C |
Integrative analysis of chromatin accessibility and genetic risk in type 1 diabetes |
poster |
|
Rodriguez Gama, Alejandro |
Signalosome nucleation enables digital innate immune proinflammatory responses |
poster |
|
Rodriguez, Lucie |
Systems-level immunomonitoring from acute to recovery phase of severe COVID-19 |
poster |
|
Rosenberg, Jacob M |
An N-of-1 trial of itacitinib for a patient with aplastic anemia associated with a gain-of-function variant in STAT1 |
poster |
|
Rumker, Laurie |
Discovering meaningful cell populations in single-cell data using patterns of transcriptional variation shared among samples |
poster |
|
Sahni, Nidhi |
Delving into proteostasis network reveals an immunogenic vulnerability in mismatch repair deficient cancer |
poster |
|
Sayeed, Md Abu |
Development of a cholera rapid diagnostic test that targets both Vibrio cholerae and vibriophage |
poster |
|
Schneider, Caitlin |
Migration-induced cell shattering due to DOCK8 deficiency causes a type-2 biased T cell response |
poster |
|
Schnell, Alexandra |
Single-cell clonotype tracing of tissue Th17 cells during CNS autoimmunity reveals the conversion of intestinal homeostatic cells to pathogenic cells |
poster |
|
Schrom, Edward C |
Quorum sensing via dynamic cytokine signaling during CD4+ T cell effector choice |
talk |
|
Selvarajoo, Kumar |
Continuous and discrete models to elucidate TRAIL-resistance mechanisms in cancers |
poster |
|
Seth, Abhinav |
An AP-1 independent gene module regulated by an NFAT2 positive feedback loop driven by persistent TCR stimulation is required for Tfh maintenance |
poster |
|
Shapiro, Virginia |
Engineered expression of the sialyltransferase ST8Sia6 protects cancer cells and islet beta cells from the immune response |
poster |
|
Shay, Tal |
Differential splicing contributes to the identity of human immune cells |
poster |
|
Shen, Lin |
A disease-associated mutation that weakens ZAP70 autoinhibition enhances responses to weak and self ligands |
poster |
|
Sheu, Katherine |
Quantifying response-specificity of macrophages to diverse immune threats |
poster |
|
Singh, Harinder |
Coupled analysis of transcriptional states and somatic hypermutation in germinal center B cells reveals role for oxidative phosphorylation in affinity maturation |
talk |
|
Singh, Satya P |
Early differentiated human Th memory cells show stable mixed-lineage activation and multi-lineage potential |
poster |
|
Skelly, Dan |
Immune crosstalk in adipose tissue modulates weight gain in response to high-fat diet |
poster |
|
Slowikowski, Kamil |
Unravelling immune and cellular responses associated with acute COVID-19 infection, symptoms and lethality at single-cell resolution |
poster |
|
Solomon, Benjamin D |
Accuracy of in silico HLA genotype prediction methods applied to single-cell transcriptome data |
poster |
|
Steier, Zoe |
Single-cell multi-omic analysis of thymocyte development reveals drivers of CD4/CD8 lineage commitment |
poster |
|
Sundaresh, Bharathi L |
Genome-wide characterization of Streptococcus pneumoniae proteins interacting with C3 complement |
poster |
|
Sureshchandra, Suhas |
Diverse homeostatic and immunomodulatory roles of macrophages in human term placenta |
poster |
|
Tan, Cyrillus |
Identifying human-murine FcγR regulation homology through a multivalent binding model |
poster |
|
Teichmann, Sarah |
Human immunity one cell at a time |
talk |
|
Thakore, Pratiksha |
Matched chromatin and transcriptional profiling reveals new regulators of Th17 plasticity for pro-inflammatory states |
poster |
|
Thomas, Molly |
Single-cell RNA sequencing reveals cell states and transcriptional signatures of immune and epithelial dysregulation that define colitis associated with immune checkpoint inhibitors |
talk |
|
Tiemeijer, Bart |
A hydrogel droplet-based microfluidics platform to probe macrophage polarization at the single-cell level |
poster |
|
Tondi, Serena |
Identification of key immune cells activated by GMMA-based vaccines in vitro |
poster |
|
Trapecar, Martin |
Dissecting gut-liver-brain immunometabolic interactions using human physiomimetic models and systems biology |
talk |
|
Trynka, Gosia |
Deciphering mechanisms of immune mediated diseases using single cell transcriptional map of T cells activation |
talk |
|
Tsang, John |
Integrating single cell and human population variations in health and disease |
talk |
|
Ucar, Duygu |
Single cell analysis of blood mononuclear cells stimulated through CD3 and CD28 shows collateral activation of B and NK cells and demise of monocytes |
talk |
|
Van Eyndhoven, Laura |
Decoding type I IFN response dynamics using droplet-based microfluidics and mathematical models |
poster |
|
Venkat, Aarti |
Archetypal analysis of antigen-specific T cell responses across conditions |
poster |
|
Vodovotz, Yoram |
Divergent COVID-19 archetypes predicted by patient-specific perturbations of a core immune regulatory network |
talk |
|
Wang, Allan |
Multiplexed, combinatorial interrogation of an enhancer cluster regulating T cell commitment |
poster |
|
Wang, Tianlu |
Caffeine-operated synthetic modules for chemogenetic control of protein activities by life style |
poster |
|
Wayman, Joseph |
Identifying regulators of an age-associated immunosuppressive CD4+ T cell population using gene regulatory network inference from single-cell genomics |
poster |
|
Westfall, Jesse E |
Understanding the immune microenvironment of Rasmussen encephalitis via single cell transcriptomics and spatial proteomics |
poster |
|
White, William L |
Precise interrogation of dynamic input/output relationships in single T cells using designed antigen-presenting scaffolds |
poster |
|
Wong, Harikesh S |
A local regulatory T cell feedback process maintains immunological homeostasis by pruning self-activated T cells |
poster |
|
Xavier, Ramnik |
Cell maps to stress control at mucosal surfaces |
talk |
|
Xing, Jianhua |
Mapping vector field of single cells |
talk |
|
Zhang, Baochun |
Insight into Epstein-Barr virus immunity and a new immune approach for B-cell malignancies |
poster |
|
Zhou, Xu |
Microenvironment controls inflammatory response in macrophages |
poster |
|
Ziegler, Carly |
Impaired local intrinsic immunity to SARS-CoV-2 infection underlies severe COVID-19 |
talk |
|
Zulu, Michael Z |
Maternal obesity compromises functional outcomes of fetal myeloid cells |
poster |