Presenting Author

Abstract Title

Talk/Poster

Abajorga, Milky K

Development of a genomic defense system against KoRV-A

poster

Aiken, Chris

HIV-1 capsid stability enables inositol phosphate-independent infection of target cells and promotes integration into genes

talk

Alvarez, Natalie N

Vpx and central polypurine tract synergistically enhance transduction efficiency, transduction kinetics, and protein expression of HIV-1 vector in human monocyte-derived macrophages

poster

Amanor, Ferdinand K

Linking the NNRTI rilpivirine to a small molecule hydrophobic tag shows promise as a potential targeted protein degrader against HIV-1 reverse transcriptase

poster

Ananth, Swetha

HIV-1 infection of resting CD4 T cells is not restricted at nuclear import but at the level of reverse transcription and integration

talk

Andino, Jonathan R

The protease cleavage sites between Gag domains direct the incorporation of a GFP marker into HIV-1 cores

poster

Anokhin, Boris

Dissecting cell type-specific particle incorporation of the HIV-1 envelope glycoprotein through fusion of permissive and nonpermissive cells

poster

Ao, Yuanyun

An intact amber-free HIV-1 system for in-virus protein bioorthogonal click labeling that delineates envelope conformational dynamics

talk

Arndt, William

Distinct morphology of immature HIV-2 particles as revealed by cryo-electron tomography

poster

Aube, Corentin

Role of HIV-1 Tat protein on HIV-1 alternative splicing

poster

Balasubramaniam, Muthukumar

Understanding HIV-1 capsid-linked viral immune evasion mechanisms

poster

Baldauf, Hanna-Mari

Murine leukemia virus (MLV) and human immunodeficiency virus (HIV) differ in their sensitivity against the antiretroviral guanylate-binding proteins (GBPs) from humans, mice and rabbits

talk

Baxter, Gloria

Transcriptomic analysis defines a role for actin cytoskeleton regulation in human retrovirus particle assembly and infectivity

talk

Behrens, Ryan T

Species-specific differences in the Gag proteins of human and simian immunodeficiency virus affect virus assembly

poster

Benlarbi, Mehdi

Plasmatic HIV-1 soluble gp120 is associated with immune dysfunction and inflammation in ART-treated individuals with undetectable viral load

talk

Bhat, Anayat

Single virus imaging of HIV-1 nuclear import and its impact on integration site selection

talk

Boso, Guney

Evolutionary conservation of an ancient retroviral gagpol gene in Artiodactyla

talk

Bosque, Alberto

Sensitizing HIV-infected cells to cell death—A chemical approach

talk

Bowen, Nicole

Vpx requires active dNTP biosynthesis to effectively counteract the anti-lentivirus activity of SAMHD1 in macrophages

talk

Bracey, Harrison E

Maturation-dependent re-localization of inositol phosphates within HIV-1 particles

poster

Bronzovich, Taylor

Vpr induction of a tissue-resident phenotype in resting T cells is a broadly conserved feature of lentiviruses

poster

Browne, Edward P

A novel high-throughput microwell assay for HIV infected cells

poster

Browne, Edward P

Defining the impact of cannabis use on immune cell phenotypes and the latent viral reservoir in people with HIV

poster

Browne, Edward P

Identifying immune correlates of total and intact HIV reservoir size

talk

Burgos, Samuel D

A novel regulator of HIV latency—CTCF chromatin insulator

poster

Burnie, Jonathan

Evaluating HIV envelope conformations at a single particle resolution using flow virometry

talk

Caico, Isabella A

Generation of a CD4-specific and inducible HIV-1 ASP transgenic mouse model

poster

Cardoso, Ricardo S

Phosphatidylinositol (4,5)-bisphosphate facilitates the recruitment of CD43, PSGL-1, and CD44 to assembling HIV particles

talk

Carlon-Andres, Irene

Lifetime-based virometry, a novel tool for assessing structural HIV-1 dynamics and Env antibody recognition

poster

Carter, Carol

HECT domain interaction with ubiquitin binding sites on Tsg101-UEV controls HIV-1 egress, maturation, and infectivity

talk

Chaudhuri, Evan

Probing CPSF6’s role in HIV-1 preintegration complex function

poster

Chen, Chaoping

HIV-1 protease inhibitor susceptibility modulated by variations in the N-terminal autoprocessing site and the Alix-binding domain

poster

Cheng, Zetao

The impact of 5′ end heterogeneity on HIV-1 RNA translation

poster

Cingoz, Oya

Retroviral genomes are directly translated after cellular entry

talk

Cisneros, William L

A first-in-class dual-acting inhibitor of PAF1C as a latency reversing and promoting agent

talk

Clark, Natasha

Adeno-associated virus delivery of Env-specific antibodies delays viral rebound following treatment interruption in SIV-infected macaques

talk

Cochrane, Alan

Context matters—Cell type roles of SR proteins in regulating HIV-1 transcription and RNA processing

poster

Cochrane, Alan

One drug for multiple bugs—Inhibition of HIV-1 and coronavirus replication by the SR kinase inhibitor Harmine

poster

Compton, Alex A

Nef from primary HIV-1 infection counteracts IFITM3 and restores virion infectivity

talk

Cornish, Daphne

CPSF6 regulates the antiviral response to HIV-1 infection via transcriptional reprograming

poster

Corte-Real, Joao V

Humanized rabbit CD4 and CCR5 receptor complex supports HIV-1 entry into rabbit cells

poster

Cullen, Harrison B

Periodic derepression of endogenous retroviruses across the cell cycle

poster

Dafonte Imedio, Alvaro

The cytoplasmic domains of gamma-type Envs are Tetherin antagonists

talk

Dash, Chandravanu

HIV-1 preintegration complex preferentially integrates the viral DNA into nucleosomes containing trimethylated histone 3-lysine 36 modification and flanking linker DNA.

talk

Davenport, Timothy

A zinc finger transcription factor IKZF3 promotes HIV-1 persistence

poster

Davids, Benem A

Uncovering pathways for activity regulated cytoskeleton-associated protein (ARC) release—Insights into Gag-like functions in the brain

poster

Decombe, Alice M

Antiviral role of internal RNA 2′-O-methylations on reverse transcription of the HIV-1 genome

poster

Deshpande, Akshay

Increased brittleness of the HIV-1 core during reverse transcription—Evidence for the cumulative damage model

poster

DeStefano, Jeffrey J

Direct measurement of dNTP and Mg²⁺ concentrations in human immunodeficiency virus (HIV) virions

poster

Diaz-Griffero, Felipe

GS-CA1 and lenacapavir block uncoating and modulate the stability of HIV-1-induced biomolecular condensates

talk

Ding, Shilei

Piperidine CD4-mimetic compounds contact the highly conserved aspartic acid 368 and expose vulnerable HIV-1 Env epitopes

poster

Dirasantha, Obaiah

TRIM5α protects baboons against infection by simian immunodeficiency viruses (SIVs)

poster

Dudek, Amanda M

A simultaneous knock-out knock-in genome editing strategy in hematopoietic stem and progenitor cells potently inhibits CCR5- and CXCR4-tropic HIV-1 infection

poster

Duggan, Natasha N

HIV-1 latency reversal by SMAC mimetics alone or in combination with other LRAs

poster

Ebrahimi, Diako

Donor-specific anti-HIV/SIV immunity mediated by APOBEC3 enzymes

talk

Eschbach, Jenna

Investigating the role of capsid stability in innate immune sensing of HIV-1 cores

poster

Etienne, Lucie

Genomic and functional impact of ancestral epidemics on bat anti-retroviral innate immunity

poster

Finzi, Andrés

Temsavir decreases HIV-1 envelope glycoproteins proteolytic cleavage

poster

Francis, Ashwanth C

Liquid-liquid phase separation activity of the C-terminal mixed-charge domain drives avid CPSF6 binding to HIV-1 capsids

poster

Freeman, Michael M

Identification and characterization of a novel endogenous HERV-K(HML-2)-derived restriction factor

talk

Fremont, Stephane

Cortical actin remodeling by the oxidoreductase MICAL1 is required for HIV-1 budding

talk

Fuchs, Nina V

A CRISPR/Cas9 based in vitro model to investigate the molecular basis of the PQBP1 dependent HIV-1 sensing complex

poster

G C, Keshav

The difference in functioning of two HIV-1 primary transcripts initiated at heterogeneous transcription start sites

poster

Gallardo, Christian M

Quantitative full-length sequencing of the HIV-1 transcriptome in primary cell derived resting CD4+ T-cells and T-cell subsets

talk

Gifford, Levi B

HIV-1 uncoating in the nucleus progresses through a distinct step of small defect formation in the capsid lattice prior to terminal uncoating

talk

Gille, Jasmin

Towards HERV-H Env protein-based tumor stratification and intervention strategies

poster

Glassey, Annemarie

Highly variable structures of proviral populations in anatomic compartments after long term antiretroviral therapy

talk

Goffinet, Christine

A novel role for ISG15 in restricting acute and persistent HIV-1 infection

poster

Goffinet, Christine

Combining latency-reversing agents with type I interferons results in accumulation of HIV-1 Env on the cell surface and sensitizes HIV-1-reactivating cells for elimination through antibody-dependent cellular cytotoxicity

poster

Gopal, Kamya

Burst size variation among integrant clones in Jurkat cells

poster

Gramberg, Thomas

HCMV facilitates HIV infection of macrophages through inactivation of SAMHD1

talk

Gray, Carley N

Integrator complex subunit 12 knockout increases provirus reactivation in the presence of other latency reversal agents

poster

Gray, Gennavieve A

Designer nucleosome substrates for probing retroviral integration

poster

Grover, Jonathan R

Pushing the envelope—Stabilizing the state 1 conformation of HIV-1 Env for structural studies

poster

Grover, Poonam

Identification of natural remission of mother-to-child retroviral transmission

talk

Gu, Feng

HIV-1 ubiquitinates the amyloidogenic C-terminal fragment of app to prevent inhibition of its vesicular replication in microglia

poster

Gull, Bushra

MMTV and RNA interference—The battle for survival

poster

Haase, Astrid

A small RNA perspective on genome integrity—piRNAs silence endogenous retroviruses and other mobile genetic elements

poster

Han, Yang

HIV-1 entry stoichiometry differs across strains, distribution of surface envelope (Env) glycoprotein trimer, and inter-protomer cooperativity in Env trimer

poster

Han, Yang

Molecular characterization of the anti-HIV-1 activity of the decameric repeats (DR) in PSGL-1

poster

Hikichi, Yuta

Mutations outside integrase lead to high-level resistance to integrase strand transfer inhibitors

talk

Ho, Ya-Chi

The single-cell epigenetic, transcriptional, and protein expression landscape of latent HIV-1

talk

Hogan, Victoria A

Conservation of the immunosuppressive domain of gamma-type Envs is due to an essential role in viral entry and fusion involving regulation of the critical disulfide bond

talk

Houmey, Myriam A

Role of HIV-1 antisense protein (ASP) in viral entry

poster

Huang, Siyu

HIV-1 gp120 promotes viral replication and upregulates N⁶-methyladenosine modification of cellular RNA in primary CD4⁺ T cells

poster

Huang, Szu-Wei

Lenacapavir inhibits virion maturation by blocking formation of capsid pentamers

talk

Indihar, Dana F

Investigating the transmission fitness of clade A and D transmitted/founder HIV using an ex vivo cervical mucosal model

poster

Ingram, Zachary

HIV-1 nuclear entry requires spatiotemporal binding of cyclophilin A and CPSF6 to capsid

talk

Ivanov, Andrey I

HIV-1 Tat facilitates KAP1 phosphorylation by interacting with PP1

poster

Ivanov, Dmitri

Allosteric regulation of dNTP depletion by SAMHD1 sheds light on the antiviral effects of dNTP imbalances

talk

Jang, Sooin

A critical role for the C-terminal mixed-charge domain of CPSF6 in nuclear HIV incursion and integration targeting

talk

Janssens, Julie

Small molecule-induced transcriptional silencing prevents HIV reactivation in cells from PWH

poster

Jing, Tao

Implications for integrase functional plasticity from the structure of the HIV-1 integrase tetramer

talk

Johnson, Jarrod S

In vitro reconstitution of HIV-1 reverse transcription, capsid destabilization, and innate immune sensing via cGAS

talk

Johnson, Margaret E

Extracting kinetics and thermodynamics of immature Gag lattice contacts by combining modeling with experiment

poster

Johnson, Welkin E

Retroviral origins of three genes in a pathogenic alphaherpesvirus of sea-turtles is evidence for horizontal gene transfer between viruses of two distinct Baltimore classes

poster

Judith, Delphine

ATG5 selectively engages virus-tethered BST2/Tetherin in an LC3C-associated pathway

talk

Kaddis Maldonado, Rebecca

Assessing the role of transcriptional condensates in RSV Gag genomic RNA selection

talk

Kaddis Maldonado, Rebecca

Co-transcriptional sorting of unspliced and spliced RNA of RSV

poster

Kane, Melissa

Determinants for Mx2-mediated inhibition of specific nuclear import pathways

poster

Kane, Melissa

Effects of the cyclophilin homology domain of RanBP2 on HIV-1 infection and Mx2 activity

poster

Kane, Melissa

Virus specificity and nucleoporin requirements for Mx2 activity are affected by GTPase function and capsid-CypA interactions

talk

Karimian Shamsabadi, Mohammad

Development of a fluorescence polarization assay for high-throughput screening of Nef inhibitors

poster

Karimian Shamsabadi, Mohammad

Nef uses a conserved pocket for downregulating SERINC3

poster

Kelenis, Demetra P

A proteome-wide, MS-based screen identifies novel SUMOylation substrates induced by HIV-1 infection

poster

Kharytonchyk, Siarhei

Absence or presence of the Inr initiator element in the core promoters of HIV-1 and HIV-2 determines the pleurality of transcription start site usage

poster

Kiarie, Irene W

Probing the role of viral protein x (Vpx) in the life-cycle of HIV-2 & its potential implication in latency

poster

Kilroy, Jonathan M

Expression of defective HIV proviruses trigger innate immune responses

talk

Kim, Eun Hye G

Dissecting the mechanisms of HIV-driven microgliosis

talk

Kirchhoff, Frank

Immune defense mechanisms and viral countermeasures—No end in sight

talk

Kleinpeter, Alex B

The effect of IP6 on HIV-1 particle production and infectivity is modulated by mutations that stabilize the immature Gag lattice

poster

Kmiec, Dorota

HIV-2 is less sensitive to ZAP restriction than SIVsmm despite higher genomic CpG content

talk

Konlian, Danielle O

Relative accumulation of deleted proviruses during antiretroviral therapy

poster

Kono, Takahide

Structural insights on RNA bridging HIV-1 Vif and antiviral factor APOBEC3G

talk

Kress, Jacob A

Structural basis of how HIV-1 Nef simultaneously recruits CD4 and MHC-I into clathrin AP1

talk

Krishnan, Anjana

A UCUG stretch is required for packaging of feline immunodeficiency virus (FIV) gRNA and is a potential Gag binding site

poster

Kumar, Abhishek

ALLINI sensitivity genetically maps to residues within HIV-1 integrase C-terminal domain

poster

Kumari, Sushila

Molecular interactions between multiple FG motifs of NUP98 and HIV-1 capsid that facilitate nuclear import

poster

Kumariya, Rashmi

Development of potent bivalent anti-HIV lectin-antibody conjugate

poster

Kvaratskhelia, Mamuka

The structural basis for viral resistance to allosteric HIV-1 integrase inhibitor STP0404 and rational development of an improved analog

poster

Lagisquet, Justine

A frequent SNP in TRIM5α strongly enhances innate immune response against LINE-1 elements

poster

Laliberte, Alexandre

Vpr attenuates antiviral immune responses and is critical for full pathogenicity of SIVmac239 in rhesus macaques

talk

Lange, Ulrike

Profiling locus-specific Human Endogenous Retrovirus (HERV) transcript signatures using multi-study-derived datasets

talk

Langley, Caroline A

Structural and evolutionary constraints on HIV-1 Vif in the context of antiviral APOBEC3 proteins

talk

Larrous, Pauline

Characterization of the viral determinants underlying the molecular conflict between SIV African green monkey Vpr proteins and the restriction factors SAMHD1 and HUSH

talk

Lau, Chuen-Yen

Visualizing the dynamics of antiretroviral treatment interruption in vivo

talk

Lecante, Arnaud

A new partner for TRIM5α ?

talk

Legrand, Alexandre

The inflammatory and tumor suppressor SAMD9L acts through a Schlafen-like box to restrict HIV and inhibit cell translation in SAAD/ATXPC

talk

Levin, Henry

The role of LEDGF in transcription is intertwined with its function in HIV-1 integration

talk

Lewis, Cat

The role of viral proteins in primary CD4+ T-cell model of HIV-1 latency

talk

Li, Chenglei

Lenacapavir disrupts HIV-1 core integrity while stabilizing the capsid lattice

talk

Li, Feng

Removal of retrotransposons by LTR-LTR recombination impairs stress response

poster

Li, Min

Intasomes assembled with full-length HIV-1 integrase and CTD facilitate structural studies by cryo-EM and reveal the role of the integrase C-terminal tail

talk

Li, Rui

The HIV-1 antisense RNA Ast promotes viral latency via epigenetic silencing of the proviral 5’LTR and is expressed in latently infected cells from ART-suppressed donors

poster

Li, Wenwei

Asymmetric HIV-1 envelope trimers bound to one and two CD4 molecules are intermediates during membrane binding

talk

Lichon, Drew M

Discerning the role of Dynein adaptors during HIV-1 infection

poster

Luban, Jeremy

IFIH1 is required for type 1 interferon induction by intron-containing RNA expressed from the HIV-1 provirus

talk

Lusic, Marina

Aquarius splicing helicase associates with HIV-1 Integrase and defines HIV-1 Integration patterns

talk

Mallorson, Rosa G

Transcriptional regulation of the HIV-1 inhibitory factor human mannose receptor 1 by the myeloid-specific transcription factor PU.1

talk

Mamede, João I

Directly labeled capsid lattice correlates progressive uncoating from the cytoplasm to the nucleus to productive HIV infection in primary cells

talk

Manganaro, Lara

In ART-naïve individuals, differences in HIV DNA content in CD4 T cell subsets are more pronounced during primary HIV infection compared to chronic

poster

Manganaro, Lara

Induction of SARS-CoV2 spike-specific CD4 TSCM is impaired in PWH with residual immune dysfunction

talk

Marchitto, Lorie

Humoral responses elicited by SARS-CoV-2 mRNA vaccine in PLWH

poster

Marchitto, Lorie

Impact of HIV-1 Vpu downregulation of CD48 on NK-cell mediated antibody-dependent cellular cytotoxicity

talk

Marin, Mariana

Fusion-competent conformation of HIV-1 Env stabilized by anti-gp41 MPER antibody is highly sensitive to SERINC5 restriction

poster

Marquez, Chantal L

Identifying host cell factors that control HIV-1 latency in different types of latent reservoirs

poster

Martin, Joanie L

Restriction activity of APOBEC3G and uracil DNA glycosylase during early HIV type-1 infection

poster

McMahon, Elyse K

Evaluating retinoids to enhance susceptibility of HIV infected CD4 T cells to cell death

poster

Melo, Claudia

Evaluating the ability of the broadly neutralizing antibody Fc-region to promote memory-like NK cells

poster

Mesner, Dejan

Cell-cell spread triggers a permissivity switch that enhances HIV infection in resting and activated T cells

talk

Min, Alice K

A novel humanized mouse latency tracking model with iPSC-derived microglia

talk

Mishra, Tarun

HIV-1 latency reversal in CD4⁺ T cells upregulates m⁶A RNA modification

poster

Miyagi, Eri

HIV-1 Vpr induces degradation of gelsolin, a myeloid cell-specific host factor that reduces viral infectivity by inhibiting the expression and packaging of the HIV-1 Env glycoprotein

poster

Monde, Kazuaki

Mechanisms of retroviral transposition in the absence of the Env proteins

talk

Morellatto Ruggieri, Luciana

The HIV-1 accessory protein Vpu traps the amino acid transporter SLC1A5 (ASCT2) in the ER and prevents its N-glycosylation

poster

Mudgal, Rajat

HIV-1 Gag interaction with tRNA via MA-HBR

poster

Mumby, Mitchell J

Phylogenetic reconstruction and functional characterization of the ancestral Nef protein of primate lentiviruses

poster

Murakami, Tomoyuki

Macropinocytosis-mediated HIV-1 internalization likely promotes HIV-1 entry into primary CD4+ T cells

poster

Murimi-Worstell, Daniel A

Differential expression of exonized human endogenous retroviruses in glioblastoma multiforme

poster

Murooka, Thomas T

Cognate DC:T cell interactions drive proliferation and survival of HIV infected T cells harboring latent provirus

talk

Mustafa, Farah

MMTV induces global downregulation of gene expression in mammary epithelial cells through epigenetic changes

talk

Newton, Lydia S

Synthetic PROTACs based on a depsipeptide macrocycle selectively degrade cyclophilin A and inhibit HIV-1

talk

Nikolaitchik, Olga A

HIV-1 usurps transcription start site heterogeneity of host RNA polymerase II to maximize replication fitness

talk

Nyalile, Thomas

Decrypting the role of eiF3h in HIV-1 replication

poster

O'Brien, Erick

HIV-1 infection of monocyte derived macrophages alters miRNA expression targeting β-catenin-TEF/LEF signaling

poster

OhAinle, Molly

TRIM34 is a TRIM5α-dependent restriction factor in primates

talk

Olusola, Babatunde

Cloning of HIV-1 subtypes A, G, and CRF-02AG from plasma viral RNA

poster

Onyango, Jackline

Establishing the role of KZFPs in HIV latency

poster

Pache, Lars

Smac mimetics as lately reversing agents in SHIV-infected rhesus macaques

poster

Padron, Adrian

Cyclophilin A promotes HIV-1 pre-integration complex (PIC) function

poster

Parent, Leslie

HIV-1 Gag nuclear import and co-localization with euchromatin histone marks near the nuclear periphery

talk

Pathak, Rajiv

cMYC and NR4A regulate stochastic reactivation of latent HIV-1

talk

Pazgier, Marzena E

Molecular basis of HIV-1 Clade A/E resistance to temsavir

talk

Perilla, Juan R

The HIV-1 capsid mechanoelastic properties facilitate nuclear import

poster

Peterlin, Boris

Mysteries of HIV latency

talk

Peterson, Jackson J

Characterization of the gastrointestinal-resident latent HIV-1 reservoir with single-cell RNA sequencing

poster

Phillips, Stacia

N⁶-methyladenosine modifications of HIV-1 RNA inhibit binding to RIG-I-like receptors

poster

Piacentini, Juliana

PQBP1 binds and destabilizes HIV-1 CA lattices in vitro

talk

Postmus, Dylan M

A novel, multi-dimensional model of HIV-1 latency illustrates functional implications of proviral diversity on efficiency and quality of latency reversal

poster

Postmus, Dylan M

Synergistic latency reversal by Bryostatin-1 and JQ-1 improves presentation of the HIV-1 Env antigen and has the potential to optimise susceptibility of reactivating cells to elimination

talk

Prakash, Prem

TREX1 preferentially degrades the integration-incompetent HIV-1 DNA due to favorable kinetics, thermodynamic, and conformational properties

poster

Preece, Benjamin J

Structural variability within the Gag lattice of immature HIV virions points to the importance of gRNA for lattice stability

talk

Prelli Bozzo, Caterina

“Traitor”—Virus-guided discovery of novel antiviral factors

poster

Raghunath, Gokul

Understanding the roles of phosphatidylserine and cholesterol in SERINC5 mediated restriction of HIV-1 infectivity

poster

Ramirez, Lindsey

Suppression of HIV-1 reactivation from latently infected CD4+ T cells by pyrrolopyridine-based allosteric integrase inhibitors

poster

Rein, Alan

Inositol hexakisphosphate in gammaretrovirus structure and replication

talk

Reuschl, Ann-Kathrin

Vpr regulates innate immune activation in resting memory T cells

poster

Richard, Jonathan

Non-neutralizing antibody-CD4 hybrids stabilize the state 2A Env conformation and mediate Fc-effector function in vivo

poster

Richard, Jonathan

Temsavir blocks HIV-1 soluble gp120-induced cytokine burst

poster

Rist, Michael

Ex vivo model of HIV insertional mutagenesis of STAT3 for therapeutic discovery

poster

Rivero-Gamez, Andres A

Structural and biochemical studies of retroviral integration onto nucleosome-bound target DNA

poster

Roberts, Casey L

Leveraging endogenous retrovirus loci to construct an evolution-guided working model of betaretrovirus Envs.

poster

Rohlfes, Nick

CPSF6's nuclear localization signal mediates HIV-1 intranuclear events following nuclear import

talk

Roth, Monica

Interaction of the gammaretroviral Envs A5 and A9a with the SLC35F2 host receptor

talk

Rousso, Itay

HIV-1 cores are elastic—Plausible role in nuclear entry

talk

Rouzina, Ioulia F

Regulation of the timing of HIV-1 uncoating by nucleocapsid protein

talk

Rubinstein, Paul

HIV reactivation after a CCR5Δ32/Δ32 allogeneic hematopoietic stem cell transplant

talk

Saffarian, Saveez

Competitive HIV budding suggests that a cis packaged gRNA₁:Gag-Pol₁₅ complex formed during translation initiates HIV assembly when it arrives on the plasma membrane and this mechanism enforces infectivity of released virions

talk

Saito, Hideki

A mislocalized nuclear pore component inhibits HIV-1 capsid entry into the nucleus

poster

Salai, Djordje

Gag assembly mediates ring-shaped lipid platform coalescence at HIV-1 budding sites

talk

Salamango, Dan J

HIV Vif inhibits the DNA damage repair kinase ATM to block activation of antiviral TRIM restriction factors

talk

Santos da Costa, Cristina

HIV-1 Nef requires AP-1 complex to induce SERINC5 retention on Golgi compartments

poster

Sawyer, Sara L

An owl monkey model of HIV-1 infection

talk

Serrano, Thomas

Characterization of the role of actin regulatory proteins in HIV-1 budding

poster

Shan, Zelin

Two new structures of HIV Integrase assemblies solved using cryo-EM

poster

Sharma, Manish

A novel labeling strategy to pinpoint HIV-1 fusion sites in cells

poster

Siddique, Mohammad Anwar

Manipulating the host cell dNTP pools influences the kinetics and dynamics of the HIV-1 early life cycle

poster

Siddiqui, Rokeya

Identification of host dependency factors that modulate nuclear import of HIV-1 cores

talk

Singh, Parmit K

CPSF6 licenses HIV-1 integration into Pol II-paused genes regulated by P-TEFb and U2 snRNP

talk

Smith, Steven

Structure-guided optimization of integrase strand transfer inhibitors (INSTIs) to enhance retention of antiviral potencies against resistant mutant forms of HIV-1 integrase

poster

Spearman, Paul

HIV infection of microglia in vitro elicits an early inflammatory response similar to that seen in chronically-infected persons with HIV-associated neurocognitive disorder (HAND)

talk

Springman-Rodriguez, Rachael

Difference in A3G-mediated anti-HIV/SIV immunity across humans and non-human primates

poster

Stricker, Erik

Deep seq dive into the endogenous retroviral part of the human genome reveals ERV variant within the LRP1B tumor suppressor gene associated with papillary thyroid cancer

talk

Stuart, Courtney D

Nup358 RBD4 modulates lentiviral capsid interactions with the cyclophilin homology domain

poster

Suinn, Stephanie

HIV-1 traffics to nuclear speckles mislocalized to the cytoplasm

talk

Sutton, Richard

Cell-based and cell-free firefly luciferase complementation assay to quantify Human Immunodeficiency Virus type 1 Rev-Rev interaction

talk

Symeonides, Menelaos

Deep analysis of 3D T cell migration using Migrate3D reveals distinct motility patterns for discrete subsets of HIV-1-infected cells

poster

Syu, Yu-Ci

Identification of the authentic HTLV-1 reverse transcription primer and role ofGag-host factor interactions in chaperoning primer annealing

poster

Tan, Xu

PSGL-1 is an evolutionarily conserved antiviral restriction factor

poster

Tan, Ying Ying

Vpx degradation of HUSH reveals a protective epigenetic gatekeeper mechanism

talk

Taube, Ran

The role of host transcription factor (ATF1) in the control of HIV gene expression and viral infection

talk

Tauzin, Alexandra

Evaluating the antibody content of HIV+ plasma leading to higher ADCC activity in presence of small CD4-mimetic compounds

poster

Taylor, Harry

Non-canonical function of splicing factor 3B subunit 1 couples CD4 T cell metabolism to HIV latency reversal

poster

Thenin-Houssier, Suzie

POLE3 is a transcriptional repressor of unintegrated linear HIV-1 DNA required for efficient virus integration and escape from innate immune sensing

talk

Timilsina, Uddhav

MARCH2 restricts HIV-1 infection as a T cell specific factor

talk

Tolbert, William D

The structural basis for macaque Fc α receptor (CD89) activation by IgA Fc

poster

Torres-Rivera, Dariana

Live-cell and superresolution microscopy studies of HIV-1 restriction by MX2

talk

Ullrich, Stephanie

A novel pulse-chase fluorescence imaging approach for the analysis of HIV-1 cell-to-cell transmission and spread

talk

Veler, Hana

Antagonism of viral glycoproteins by guanylate binding protein 5

talk

Vershinin, Michael D

A deep learning microscope designed for imaging HIV

poster

Vreux, Laure

Role of the cellular factor BCL11b in the transcriptional regulation of HTLV-1 (human T-cell leukemia virus type 1)

poster

Vuong, Hung

Efficient packaging of HIV-1 genomes by heterologous RNA-binding domains

talk

Waheed, Abdul A

Neutral Sphingomyelinase 2 is Required for HIV-1 maturation

poster

Wallace, Courtney G

Defining mechanisms of epigenetic regulation of transcriptional control in HIV-1 infected human monocyte derived macrophages

poster

Wang, Qiankun I

CARD8 inflammasome restricts HIV-1 infection in resting CD4⁺ T cells

talk

Wang, Tian

Investigating the role of endogenous retroviral elements in nuclear export of intron-retaining transcripts in the human genome

poster

Waxman, Brandon

Heparanase blocks retrovirus infection by targeting proviral transcription

poster

Weiskopf, Erika N

The HIV-1 capsid enters the nuclear pore complex by partitioning into its FG-hydrogel

talk

Williamson, David J

Exploring Env dynamics with FLIM-FRET

poster

Woottum, Marie

HIV-1 cell-to-cell spreading in macrophages from infected T cells bypasses host cell restriction factors by a mechanism independent of the counteracting viral auxiliary proteins

poster

Wright, Jordan M

Novel SIN LTRs with enhanced polyadenylation activity improve transcriptional insulation of lentiviral vectors from both 5’ and 3’ genic regions in target cells

poster

Wright, Jordan M

Simplifying the lentiviral vector-derived RNA packagome through mutation of the Major Splice Donor requires titre-rescuing mechanisms that intersect U1 snRNA functions

poster

Wu, Li

SAMHD1 impairs type I interferon induction through the MAVS, IKKε, and IRF7 signaling axis during viral infections

poster

Wu, Xueling

Broadly neutralizing IgA response to HIV infection

talk

Wu, Yuanfei

Efficient HIV-1 propagation depends on active CDC42

talk

Wu, Yuntao

CD34 is a host antiviral protein limiting retroviral infection and replication in hematopoietic progenitor cells

poster

Xie, Maorong

HIV-1 Vpr antagonises interferon by suppressing STAT nuclear transport

poster

Xiong, Yong

Structural insights into PPP2R5A degradation by HIV-1 Vif

talk

Xu, Junjie

PNMA2 forms non-enveloped virus-like capsids that trigger paraneoplastic neurological syndrome

talk

Yang, Huixin

Identification of determinants in the HTLV-1 capsid carboxy-terminal domain that are critical for virus particle assembly

poster

Yaple, Marianne

Acidification of the recycling endosome is required for optimal Nef-dependent MHC-I downmodulation and complex formation

talk

Yoh, Sunnie M

Structural regulation on PQBP1 sensing of HIV-1 capsid and innate immune activation

talk

Yurkovetskiy, Leonid

Retroviral determinants of HUSH-mediated silencing

talk

Zamborlini, Alessia

dNTPase or not (only) dNTPase, that is the question

talk

Zhang, Robert Z

Retroviral determinants for the generation of protective antibody responses

talk

Zheng, Yong-Hui

MLV glycoGag and EIAV S2 antagonize SERINC5 more effectively than HIV-1 via a complex multipath degradation mechanism

poster