Regulatory & Non-coding RNAs
May 17 - 21, 2022

You must register for the meeting in order to submit abstracts.
After registering you will be sent a web link for abstract submission by email.
You may copy and paste your abstract from Word, Google Docs, or Notepad; abstracts are limited to ~2900 characters.

Program information: An electronic version of the program abstract book will be sent 3-5 working days prior to the first day of the meeting, and hard copies will be available for collection upon your arrival at Cold Spring Harbor Laboratory. First night and keynote speakers are informed of their session date and time, otherwise program information is only available upon release of the electronic version of the abstract book. The reason we do this is to try and maximize interactions by encouraging participants to stay for the duration of the meeting.

Please check your email for talk length, in-person and virtual poster instructions, and how to have your poster printed at CSHL for collection upon arrival. 

Abstract Status

Presenting Author

Abstract Title

Presentation

Alves, Cristiane

Small RNAs, transposable elements, and big genomes—Wollemia nobilis and its insights towards a better understanding of plant genomic regulation and evolution

talk

Amaral, Murilo Sena

Long non-coding RNAs in Schistosoma mansoni extracellular vesicles

talk

Bagci, Ayca

Developing tools to understand piRNA precursor trafficking

poster

Bai, Xiaowen

Integrated analysis of microRNA expression and networks of excitatory/inhibitory neurons decodes the molecular mechanisms of anesthetic-induced neurodegeneration

virtual poster

Bailey, Shannon

Uncovering the mechanism of GTSF1-facilitated PIWI cleavage

poster

Bechara, Elias

The RNA-binding protein SAM68 regulates cardiomyocyte differentiation by enhancing Gata4 translation via circRNA Large

poster

Ben-Tov Perry, Rotem

Roles of Silc1 lncRNA in the peripheral and central nervous system

talk

Berube, Benjamin T

RNAi mediates drive in teosinte-maize hybrids

poster

Biasini, Adriano D

Exploring the contribution of miR-34/449-5p to spermatogenesis

poster

Briones Martin del Campo, Marcela C

Long non-coding RNAs that are required for robust cell growth in Ewing sarcoma

poster

Burenina, Olga Y

Novel non-coding RNA CHOL is dysregulated in liver cancers

virtual poster

Cazalla, Demian

Allosteric regulation of noncoding RNA function by microRNAs

talk

Chang, Howard

Genome regulation by long noncoding RNAs

talk

Chang, Ming-Wen

LncFAM promotes myogenesis by recruiting hnRNPL to MYBPC2 promoter

poster

Chen, Chun-Kan

Structured elements drive extensive circular RNA translation

poster

Chen, Ling-Ling

Circular RNAs as potent inhibitors of PKR

virtual talk

Crerar, Hamish G

Diminished miRNA activity is associated with aberrant cytoplasmic intron retention in ALS pathogenesis

talk

D'Adda di Fagagna, Fabrizio

The role of telomeric non coding RNA in telomere dysfunction, cellular senescence and disease

talk

Dar, Mohd Saleem

Divergent lncRNA Dnmt3bas regulates the inducible expression and alternative splicing of Dnmt3b

poster

Das, Arpan

The miR-200 family inhibits embryonic specifications of sebaceous progenitors by antagonizing BMP signaling

poster

Das, Troyee

Genetic variants within long non coding RNA loci—Role in female cancers

virtual poster

Deka, Bhagyashree

Understanding the role of microRNAs in the post-transcriptional regulation of RNPS1 gene

virtual poster

Desideri, Fabio

Noncoding RNA shaping gene expression—Implications in neuromuscular physiopathology

poster

Dutta, Anindya

Mechanisms of action of two lncRNAs—The tumor-suppressive DRAIC and the differentiation-promoting MUNC

talk

Farberov, Svetlana

Structural features within the NORAD long noncoding RNA underlie efficient repression of Pumilio activity

poster

Ferragut Cardoso, Ana

miR-186 interacts with arsenic to induce aneuploidy in human keratinocytes

poster

Fishman, Lior

A systematic characterization of cell-type specific dynamic mRNA regulatory programs during the maternal-to-zygotic transition

poster

Fletcher, Claire E

A non-coding RNA balancing act—miR-346-induced DNA damage is limited by the long non-coding RNA, NORAD, in prostate cancer

poster

Frederick, Pierre-Marc

A HSP40 co-chaperone modulates the function of a specific miRNA silencing complex in C. elegans

poster

Gainetdinov, Ildar

Why do animals need two Argonaute families with different catalytic properties?

talk

Gajic, Maria

Target-dependent siRNA suppression distinguishes self from non-self endogenous siRNAs in C. elegans germline

poster

Galagali, Himani Anand

DAF-16 inhibits NHR-23 and let-7 family of microRNAs during dauer in C. elegans

poster

Galia, Liraz

A newly identified transcript of the lncRNA, HOXA11os, promotes gut homeostasis through metabolic regulation of immune response

talk

Ghosh, Byapti

Investigating the non coding RNA mediated oncogenicity in induced pluripotent stem cell derivatives

virtual poster

Ghosh, Subho

Aerobactin mediated metabolic activity regulates swarming motility and growth in minimal medium in Enterobacter

virtual poster

Goldsworthy, Sian

MicroRNA regulation of the Wnt pathway during branchial arch development

poster

Goswami, Binita

The complex life of a microRNA—Exosomal export by HuR and transcription regulation by p53 control biphasic dynamics of microRNA-125b in response to genotoxic stress

virtual poster

Grammatikakis, Ioannis

An evolutionarily conserved AU-rich element in the 3’UTR of a transcript misannotated as lncRNA regulates RNA stability

virtual poster

Grecco, Andres

Whole worm microRNA silencing in cestodes

virtual poster

Grimme, Acadia L

Elucidating the mechanism of regulation of the mir-35 family in C. elegans

poster

Guo, Jimmy

CLIP-IT—A massively multiplexed method for mapping RNA-protein interactions in vivo

talk

Gupta, Yogesh

RNA binding to human METTL3-METTL14 restricts N6-deoxyadenosine methylation of DNA in vitro

virtual talk

Guttman, Mitchell

RNA promotes the formation of spatial compartments in the nucleus

talk

Harris, Jenna

Unraveling the role of aging-related circRNAs in Drosophila melanogaster

talk

Hayman, Daniel

A microRNA-mediated regulatory network in bone formation and resorption

poster

Hazra, Rasmani

Platr4 is an ESC-specific lncRNA that exhibits its function downstream on mesendoderm lineage commitment

talk

Henninger, Jonathan

Transcription factors harbor functional RNA-binding domains

talk

Hermand, Damien

Transcriptome-wide mapping of dihydrouridine (D) reveals that mRNA dihydrouridylation is essential for meiotic chromosome segregation

talk

Hiers, Nicholas M

Determining the target-RNA directed miRNA degradation interactome in cancer

poster

Hong, Tian

Nonmodular oscillator and switch based on RNA decay drive regeneration of multimodal gene expression

poster

Insco, Megan L

Oncogenic CDK13 mutations impede nuclear RNA surveillance

talk

Joshua-Tor, Leemor

A shape-shifting nuclease unravels structured RNA

talk

Kakumani, Pavan Kumar

CSDE1 promotes the biogenesis of miR-451

poster

Kaletsky, Rachel

C. elegans interprets bacterial non-coding RNAs to learn and transgenerationally transmit pathogen avoidance behavior

talk

Kennedy, Scott

poly(UG)-tailed RNAs in genome protection and epigenetic inheritance

talk

Khan, M. Jawad

Identification of endogenous circular RNAs in the pathogenesis of coronary heart disease

virtual poster

Khelifi, Gabriel

Regulation of the core pluripotency networks by a novel long non-coding RNA

poster

Kim, Narry

MicroRNA processing

talk

Kim, Yoon Young

Expression of microRNAs regulating the receptivity of the endometrium in murine and NHP models

poster

Kim, Yoon Young

Role of Piwil and microRNAs in the development of murine ovarian follicles in vitro

talk

Kim, Yoosik

RNA methylation by NSUN4 marks mitochondrial double-stranded RNAs for degradation

poster

Kingston, Elena R

Endogenous transcripts direct microRNA degradation in Drosophila, and this targeted degradation is required for proper embryonic development

talk

Kjems, Jorgen

Characterization of full-length brain-derived circRNAs and their function in neural development

talk

Konrad, Kalin D

Post-transcriptional regulating during mitosis

poster

Kota, Janaiah

miR-29a is downregulated in chronic pancreatitis and contributes to the fibro-inflammatory regulation of the disease

virtual poster

Kotagama, Kasuen

Exploring the regulation and function of an ancient microRNA family in C. elegans

poster

Kotani, Ai

Novel cccDNA-binding repeat RNAs regulate histone modification through repeat binding protein

poster

Kretov, Dmitry

The miR-144/Hmgn2 regulatory axis orchestrates chromatin regulation during erythropoiesis

poster

Krichevsky, Anna

The circuit of lncRNA, miRNA, and snRNA shaping glial cell fate and transformation

poster

Ku, Doyeong

SLIRP amplifies antiviral signaling by stabilizing mitochondrial double-stranded RNA

poster

Kuhn, Claus D

Enhancer RNAs stimulate Pol II pause release by harnessing multivalent interactions to NELF

poster

Lai, Eric C

Endogenous RNAi silences incipient sex chromosome conflicts during Drosophila speciation

talk

Landweber, Laura

Regulation of genome reorganization in the ciliate Oxytricha

talk

Lee, Soo Mi

Cellular microRNA-127-3p suppresses oncogenic herpesvirus-induced transformation and tumorigenesis via down-regulation of SKP2

talk

Lee-yow, Yannick C

Applying single-cell and CRISPR technologies to understanding circRNA biogenesis and function

poster

Lekva, Tove

The long non-coding RPPH1 is decreased in leucocytes and increased in plasma from women developing preeclampsia

poster

Li, Tianqi

Translational regulation of target-directed miRNA degradation

talk

Li, Yingshan

A novel class of long small RNAs, with Dicer-independent biogenesis, associates with Argonaute1 and is up-regulated by nutrient deprivation in the alga Chlamydomonas

poster

Licholai, Sabina

Circular RNAs as potential biomarker of abdominal aortic aneurysms

poster

Maniataki, Elisavet

The pi-cloud hypothesis—piRNA loci and their very long primary products as redundant and promiscuous interaction modules in nuclear folding

poster

Marques, Filipa C

GBAP1 long noncoding RNA modulates survival of senescent cells through GBA1

poster

Martinez-Terroba, Elena

Accumulation of the long noncoding RNA Malat1 is a central driver and therapeutic target in metastatic lung cancer

talk

Mas, Aina

ORC1 binds to cis-transcribed RNAs for efficient activation of replication origins

talk

McJunkin, Katherine

Cluster assistance factors ERH and SAFB2 globally inhibit miRNA biogenesis in the C. elegans embryo

talk

Meerson, Ari

Obesity and cancer—A microRNA story

virtual poster

Mendell, Joshua

Regulation and function of noncoding RNAs—Lessons from NORAD

talk

Militello, Giuseppe

Generation of enhanced artificial miRNAs for RNAi-based therapeutics

poster

Mineo, Marco

Improving cancer immunotherapy by targeting the LncRNA INCR1

poster

Monziani, Alan

In vivo regulation of neurodevelopment mediated by the Reno1-Bahcc1 axis

poster

Morlando, Mariangela

Circ-Hdgfrp3 travels along neuronal processes and its trafficking is impaired in motor neurons carrying ALS-linked FUS mutations

virtual talk

Munkhzul, Choijamts

Wnt/microRNA double-negative feedback regulation balances proliferation to facilitate the differentiation of adipocyte precursors

poster

Nakagawa, Shinichi

Regulation of alternative splicing by short RNAs—4.5SH functions as an antidote for deleterious inclusions of cassette exons containing antisense insertions of retrotransposon SINE B1

talk

Nakanishi, Kotaro

Biogenesis of tiny RNAs

talk

Nguyen, Thi Thanh My

Proximity labeling reveals protein interaction network of Zucchini

poster

Noriega-Rivera, Ricardo A

Upregulation of the long non-coding RNA CASC10 promotes cisplatin resistance in high-grade serous ovarian cancer

poster

Orellana, Esteban A

tRNA inhibition as cancer therapy

talk

Patop, Ines L

The splicing factor MBL forms a self-regulatory circuit by modulating back splicing in a cell type and isoform specific mechanism

poster

Peschiaroli, Angelo

ΔNp63-mediated regulation of NEAT1 controls epidermal differentiation

poster

Pewarchuk, Michelle E

Development-associated PIWI-interacting RNAs are important for lung tumourigenesis

poster

Pinheiro, Amanda

Coordinating metabolism and differentiation through the Dlk1-Dio3 noncoding RNA cluster

talk

Pinkney, Holly

Spatial lncRNA signatures in colorectal cancer

poster

Ramadei, Anthony

Regulation of p21 expression by a sense long non-coding RNA generated by alternative polyadenylation during the DNA damage response

virtual poster

Ramnarine, Varune Rohan

The long noncoding RNA H19 regulates tumor plasticity in neuroendocrine prostate cancer

poster

Refojo, Damian

Influence of circular RNA topology on microRNA stability

talk

Refojo, Damian

Altered neurotransmission and anxiogenic response in CircTulp4 KO mice

poster

Remsburg, Carolyn

RNA localization to the mitotic spindle

poster

Ross, Caroline J

Decoding the functional importance of sparse highly conserved short motifs in lncRNA genes

poster

Rupert, Jakob

The effect of RNA on alpha synuclein aggregation

poster

Saitoh, Noriko

ELEANOR non-coding RNAS associate with chromatin and regulate breast cancer recurrence

virtual poster

Salzman, Julia

Cell-type specific post-transcriptional regulation is pervasive

virtual talk

Shang, Renfu

Regulated dicing of pre-mir-144 via reshaping of its terminal loop

virtual poster

Shechner, David M

O-MAP—A unified method for discovering RNA-interacting proteomes, transcriptomes, and genomic loci in intact cells

talk

Shen, Haoqing

ADARs act as potent regulators of circular transcriptome in cancer

virtual poster

Simard, Martin

Specific Argonaute phosphorylation regulates the miRNA binding and function during C. elegans development

poster

Song, Jia L.

microRNA-1 represses signaling pathway components to impact embryonic structures derived from all three germ layers

poster

Stankiewicz, Pawel

Ultra-conserved genomic regions, including lung-expressed lncRNAs, within the FOXF1 enhancer are critical for human lung development

virtual poster

Stribling, Daniel

Discovery and functional exploration of the non-canonical human miRNA—miR-snaR

poster

Subramaniam, Noeline

The contribution of angiogenic lncRNAs to tip-stalk patterning in the vascular endothelium

virtual poster

Sun, Qianwen

DDM1-facilitated R-loop resolution and H2A.Z exclusion prime heterochromatin formation in Arabidopsis

virtual talk

Telkar, Nikita

Investigating the small non-coding RNA transcriptome of the human placenta

poster

Teng, Mona

Circular RMST regulates ASCL1 in neuroendocrine tumours of the prostate and lung

poster

Tollis, Paolo

Decoding the role of the lncRNA HOTAIRM1 in human motoneurons

poster

Tripathi, Shraddha

A Japanese encephalitis virus (JEV) induced host long non-coding RNA (lncRNA) regulates neuronal cell death

virtual poster

Ule, Jernej

New methods and insights into RNP condensation across the transcriptome

talk

Valadkhan, Saba

Distinct, context-dependent bimodal function of a long non-coding RNA in neurogenesis and cancer

poster

Vidigal, Joana

Co-transcriptional control of transposable elements by AGO2 in mouse quiescent cells

talk

Vieux, Karl-Frederic

Screening by deep sequencing to identify mediators of RNA tailing in C. elegans

poster

Vychytilova, Petra

Small extracellular vesicles as promising source of novel biomarkers for early non-invasive detection of colorectal cancer

virtual poster

Whipple, Amanda J

Unambiguous mapping of snoRNA interaction sites with chimeric eCLIP

poster

Wilusz, Jeremy E

Modulation of PP2A recruitment by IntS6 enables Integrator complex activity to be tuned in a gene-specific manner

talk

Wolin, Sandra

Damaged tRNAs as signaling molecules

talk

Yang, Minglei

Freezing temperatures enhance R-loop formation and a blockage on the template strand to suppress Arabidopsis FLC transcription

virtual talk

Yi, Chengqi

Absolute quantification of single-base m6A methylation in the mammalian transcriptome

virtual talk

Yoon, Jimin

Targeting mitochondrial double-stranded RNAs ameliorates autoimmune characteristics of Sjogren’s syndrome

poster

Yuan, Yinan

Genome-wide characterization of R-loops in forest tree genome using non-antibody nucleases approaches

poster

Zheng, Thomas

The long noncoding RNA lnc-FANCI-2 restricts RAS signaling but maintains constitutive IFN response via TLR3 and MCAM in HPV-infected cervical cancer cells

virtual talk