|
Presenting Author |
Abstract Title |
Talk/Poster |
|
Abraham, Neeta |
Investigating the impact of HTT splice modulators on the levels and localization of HTT canonical, cryptic and HTT1a transcripts in cell and animal HD models |
poster |
|
Abulimiti, Amina C |
DJ-1-mediated metabolic efficiency determined the vulnerability of midbrain dopaminergic neurons in Parkinson’s disease |
poster |
|
Abushawish, Ahmed A |
Mitochondrial heterogeneity driving dopamine neuron degeneration |
talk |
|
Akay, Leyla A |
Dissecting the molecular correlates of cognitive resilience to Alzheimer’s disease |
poster |
|
Al-Ali, Haya J |
Kv7.2/7.3 channels as therapeutic targets for treating epilepsy and neurodegeneration |
poster |
|
Albertson, Richard |
The temporal landscape of age-related genetically triggered neurodegeneration |
poster |
|
Alhosani, Khalood M |
Septin 5 and 6, dual regulators of stability and maintenance of the axon initial segment, may be involved in neurodegenerative pathologies |
poster |
|
Ali Ahmadi, Mitra |
Pharmacological reduction of plasma BCAAs promotes neuronal health markers in the hippocampus of Alzheimer’s disease mouse model |
poster |
|
Ali, Tariq |
In silico optimization of peptides as inhibitors of α-synuclein aggregation and toxicity |
poster |
|
Andersen, Olav |
A novel therapeutic approach for Alzheimer’s disease targeting patients with pathogenic variants in SORL1 exon 23 using antisense oligonucleotide mediated exon skipping |
talk |
|
Aromokeye, Rukayat A |
Discovery of novel small molecule ligands of the RNA-binding protein G3BP1, which regulate stress granule formation |
poster |
|
Arya, Shruti |
Novel small molecule inhibits TDP-43 aggregation and restores function in models of ALS/FTD |
poster |
|
Ashkenazi, Avraham |
Pathologic α-synuclein cell-to-cell spread by lipid translocases in Parkinson’s disease |
poster |
|
Atwater, Emily |
Investigating ASC immunostaining in Alzheimer’s disease |
poster |
|
Ayata, Pinar |
The neurodegenerative impact of cellular stress responses linked to dark microglia |
poster |
|
Baek, Yeongjin |
Structural insight into the SOD1 amyloid filament formation |
poster |
|
Bai, Yu |
The function of TREM2 in LSD1-induced neurodegeneration |
poster |
|
Bailey, Hannah |
The effect of pharmacological compounds on LRRK2-lysosome interactions |
talk |
|
Basu, Bijoya |
Signaling in the cerebellum modulates associative memory |
poster |
|
Basu, Himanish |
Gasdermin-E—A key driver of disease progression in frontotemporal dementia |
poster |
|
Baumert, Ryan M |
Gabapentin receptor α2δ-1 controls neuronal nutrient-dependent endolysosomal signaling via interacting with Huntingtin |
poster |
|
Bautista Alvarez, Julied F |
Axonal thickness and expression of growth axon protein (GAP-43) below subgenual cingulate Area 25 in early chronic traumatic encephalopathy (CTE) |
poster |
|
Birekdar, Inas K |
Gardenia jasminoides fruit extract exhibits a neuroprotective effect in an in vitro neurotoxicity model |
poster |
|
Blanchard, Joel W |
Investigating and therapeutically targeting APOE4-mediated cerebrovascular dysfunction |
talk |
|
Blumenfeld, Jessica |
Neuron-specific expression of APOE4 is sufficient to promote tau-mediated gliosis and neurodegeneration |
talk |
|
Bolat, Dinara |
Examining the relationship between calcium dysregulation and tau hyperphosphorylation in Alzheimer’s disease |
poster |
|
Borbolla Jimenez, Fabiola Vianet V |
Polymeric nanoparticles loaded with (-) Epicatechin—Targeted mitigation of oxidative stress in a spinocerebellar ataxia type 7 cellular model |
poster |
|
Boros, Ben D |
Antisense oligonucleotide masking of a common mRNA cis-regulatory element amplifies protein expression |
poster |
|
Borsello, Tiziana |
Selective JNK3 inhibition protects against acute and chronic neurodegenerative injuries |
poster |
|
Boulger, Samuel L |
Identification of neuronal subtypes selectively vulnerable to depletion in Alzheimer’s disease using imaging mass cytometry |
poster |
|
Bouris, Vangelis |
Identify genetic modifiers of prion neurotoxicity and cell-to-cell transfer through genome-wide CRISPR knockout screens |
poster |
|
Boyden, Edward |
Technology for analyzing and repairing the brain |
talk |
|
Bright, Anna |
Investigating the effects of APOE genotype and ER stress on myelination in Alzheimer’s disease using iPSC-derived brain tissues |
poster |
|
Brose, Nicholas J |
Parkinson’s disease-linked VPS35 controls astrocyte development through regulation of membrane protein trafficking |
poster |
|
Browne, Danielle |
Hypochlorous acid modification of AD-like tau seeds substantially reduces seeding capacity |
poster |
|
Calliari, Anna |
HDGFL2 cryptic proteins establish presence of TDP-43 pathology in neurodegenerative diseases |
poster |
|
Casali, Brad T |
Sex chromosomes and gonads modify microglial-mediated pathology in a mouse model of Alzheimer’s disease |
poster |
|
Chan, Tze Khee |
Validating Stathmin-2 as a therapeutic target for amyotrophic lateral sclerosis in human induced pluripotent stem cells-derived motor neuron |
poster |
|
Chang, Andrew |
Differential effects of N-linked glycosylation on the aggregation of TMEM106B |
poster |
|
Chen, Jun-An |
The motor neuron m6A repertoire governs neuronal homeostasis and augmented m6A production mitigates ALS symptom manifestation |
poster |
|
Chen, Xu |
Lipid metabolism in tauopathy brain:pathophysiology and intervention |
poster |
|
Chen, Yelin |
The development of ApoE C-terminal domain as a treatment for Alzheimer's disease by inhibiting APP γ-cleavage |
talk |
|
Chen, Ziheng |
Transcriptional and epigenetic effects of common and rare genetic variants associated with Alzheimer’s disease in brain and immune cells |
poster |
|
Cheong, Agnes |
Preformed fibrils induced neurodegenerative disease relevant transcriptomic profile in the in vitro human iPSC CNS model system |
poster |
|
Chern, Yijuang |
Modulation of adenosine deficiency by ENT1 inhibition improves neuronal connectivity and metabolic abnormalities in a mouse model of tauopathy |
poster |
|
Chiu, Isaac |
Gasdermin E—An innate pore-forming molecule that drives neurodegeneration in ALS and FTD |
talk |
|
Choi, So Yoen |
GSDME is a major mediator for neurodegeneration in MAPT-FTD through calpain activation |
poster |
|
Chopra, Atul |
Asprosin gene therapy restores associative memory deficits in Alzheimer’s disease |
poster |
|
Chung, Sunwoo |
The blockade of STING activation alleviates microglial dysfunction and a broad spectrum of Alzheimer’s disease pathologies |
talk |
|
Cuni-Lopez, Carla |
Lipid droplet-associated pathways modulate APOE-driven risk and protection for Alzheimer’s disease |
poster |
|
Damian, Corina |
Cholecystokinin modulation of microglial function and neuroinflammation in Alzheimer’s disease |
poster |
|
De Strooper, Bart |
Xenotransplantation to model the human specific pathology in Alzheimer’s disease |
talk |
|
Del Rosso, Giulia |
The role of TDP-43 loss of function in RNA splicing in age-related neurodegenerative diseases |
poster |
|
Di Paolo, Gilbert |
Decreased lipidated ApoE-receptor interactions confer protection against pathogenicity of ApoE and its lipid cargoes in lysosomes |
talk |
|
Diamond, Marc |
Functional classification of tau prion strains |
talk |
|
Dixon, Gary |
RNA dysregulation in iNeurons with the FTD-causing MAPT V337M mutation |
poster |
|
Duan, Yangyang |
AAV-mediated genome editing persistently alleviates Alzheimer’s disease pathologies in mice for over 2 years |
poster |
|
Duennwald, Martin L |
Parkin oxidation and misfolding in Parkinson's disease |
poster |
|
Eck, Randall J |
Genetic depletion of the E3 ubiquitin ligase adaptor SPOP rescues tau aggregation, neurodegeneration, and behavioral deficits in models of tauopathy |
poster |
|
Eyo, Ukpong B |
Microglial modulation of cerebral basal capillary tone in health and Alzheimer’s disease |
talk |
|
Fan, Yujie |
Self-assembling synuclein induces Parkinsonian pathology in vitro and in vivo |
poster |
|
Fayzullina, Marina |
Investigation of disease-specific tauopathy cell models for tau aggregation and pathogenesis |
poster |
|
Feigenbutz, Dennis |
Temporally resolved single-nucleus RNA-sequencing profiling of the cortex reveals mechanisms of neuronal vulnerability in Huntington’s disease |
poster |
|
Fisher, Raven |
Investigating histone PTM and chromatin changes linked to C9orf72 FTD/ALS |
poster |
|
Fitzpatrick, Anthony |
Structures of LRP2 reveal a molecular machine for endocytosis |
poster |
|
Fogo, Garrett |
Interrogating genetically-encoded mechanisms of proteostasis in human iPSC-derived neurons in the context of Alzheimer’s disease |
poster |
|
Fremuth, Leigh |
Neuraminidase 1 regulates neuropathogenesis by governing the cellular state of microglia via modulation of Trem2 sialylation |
poster |
|
Fu, Yifan |
The familial Alzheimer’s disease APP-V717I mutation results in impaired anti-oxidative stress function in iPSC-derived neurons |
poster |
|
Fu, Zhongxiao |
Microglia modulate cerebral blood flow and neurovascular coupling through ectonucleotidase CD39 |
poster |
|
Fushiki, Akira |
Cell-type susceptibility and the progression of symptoms in Parkinson’s disease |
poster |
|
Gandy, Sam |
Endogenously generated Dutch-type toxic nonfibrillar Aβ oligomers dysregulate presynaptic neurotransmission in the absence of detectable inflammation—Validation with oligomer-detecting antibodies and ligands |
poster |
|
Gomez Giro, Gemma |
Inhibiting LRRK2-PD using novel small GTPase inhibitors in microglia and assembloids |
poster |
|
Gorodetski, Lilach |
Disruption of Dvl2-mediated planar cell polarity signaling and synaptic plasticity in mouse models for Alzheimer's disease |
poster |
|
Groveman, Bradley R |
The role of astrocytes in prion infection of human cerebral organoids |
poster |
|
Guldner, Ian H |
Labeling neuronal proteomes across lifespan reveals age-related proteostasis decline with links to synaptic dysregulation and proteinopathies |
talk |
|
Guneykaya Cinar, Dilansu |
The Alzheimer’s disease risk gene Ms4a6d regulates microglial antigen presentation in tauopathy |
poster |
|
Guo, Caiwei |
TDP-43 and splicing factors regulate cryptic RNA splicing of synaptic genes in ALS/FTD |
poster |
|
Haass, Christian |
TREM2 expression level is critical for microglial state, metabolic capacity and efficacy of TREM2 agonism |
talk |
|
Hamdan, Hamdan |
Novel genetic variants associated with neurodegenerative diseases identified in children with autism spectrum disorder in the United Arab Emirates |
poster |
|
Han, Marina |
The endoplasmic reticulum unfolded protein response modulates mutant TDP-43 proteinopathy in C. elegans |
poster |
|
Haque, Zobayda Farzana |
Dose-response of BT2 on AD mouse models |
poster |
|
Hartigan, Kelly |
Neuronal IDOL influences neuronal composition and signaling in the context of amyloid pathology |
poster |
|
Hayne, Margaret |
SPG11 is a regulator of brain inflammation and microglial function in neurodegeneration |
poster |
|
Holtzman, David |
APOE4 depletion in the astrocytes and vascular fibroblasts affects cerebral amyloid angiopathy (CAA) related pathology and vascular dysfunction in differing ways |
talk |
|
Horak, Martin |
Development of a novel open-channel blocker for GluN1/GluN2A NMDA receptors with slower kinetics than memantine |
poster |
|
Hu, Fenghua |
Physiological and pathological functions of TMEM106B, a protein intimately linked to brain aging and brain disorders |
talk |
|
Huang, Shijiao |
Neural targeting of aging and neurodegenerative diseases |
poster |
|
Hubbard, Isabel |
The differential toxic effects on neurons of glial induction of C9orf72-encoded RNA vs arginine rich dipeptide repeats in Drosophila |
poster |
|
Imiolek, Magdalena D |
The use of phytocannabinoids and MCC950 as potential treatments of reactivity in human-induced pluripotent stem cell-derived astrocytes |
poster |
|
Ittner, Arne |
Control of robust memory engrams by encoding-specific tau phosphorylation |
poster |
|
Iyer, Abhirami |
Cell autonomous microglia defects in a stem cell model of frontotemporal dementia |
poster |
|
Jackson, Aimee |
Widespread and durable knockdown of HTT in non-human primate brain by a novel oligonucleotide modality |
talk |
|
Jiang, Wei |
Suppressing APOE4-induced neural pathologies by targeting the VHL-HIF axis |
poster |
|
Jin, Xin |
Scalable investigation of gene function and organ-wide action with in vivo Perturb-seq |
talk |
|
Johnson, Lance |
Cell-type Specific APOE4 to APOE2 ‘switching’ in astrocytes or microglia differentially modulate the glial response to amyloid pathology |
talk |
|
Jurado Coronel, Juan |
Oxidative stress-induced Nrf2 misfolding in Parkinson’s disease |
poster |
|
Kadamangudi, Shrinath |
Unraveling synaptic tauopathy in Alzheimer’s disease—the role of Aβ and selective neuronal vulnerability in tau spreading and synaptic dysfunction |
poster |
|
Kanchi, Rishi |
Modeling the effects of astrocytic GLT-1 downregulation and therapeutic agents on tripartite synapse in ALS |
poster |
|
Kawakami, Hideshi |
Characterization of optineurin and its role in the pathogenesis of neurological and systemic inflammatory diseases |
poster |
|
Kaye, Sarah |
Hyperlipidemia impairs microglial function and worsens AD pathology |
poster |
|
Kersey, Holly N |
Single-cell RNA-sequencing analysis of PU.1 overexpression and knockdown in mouse brain |
poster |
|
Keulen, Zahara M |
Using chemogenetic manipulation to study second messenger-mediated activation states in microglia |
talk |
|
Khanam, Afsana |
Delivery of neurotrophic factor-α1/ carboxypeptidase E gene in the cortex prevents neurodegeneration induced by mild traumatic brain injury in mice |
poster |
|
Kim, Myunghee |
Development of glycosaminoglycan-interacting small molecule (GISMO) compounds for the treatment of Alzheimer’s and Parkinson’s diseases |
poster |
|
Kuan, Chia-Yi (Alex |
[18F]Fluoroedaravone—a positron emission tomography probe for imaging oxidative stress in the central nervous system |
poster |
|
Kunach, Peter |
Development of an amyloid dye from a tau-PET ligand |
poster |
|
Kundu, Debapriya |
Deciphering the mechanistic link between O-GlcNAcylation and Tau proteinopathy in Alzheimer's Disease |
poster |
|
Lacrampe, Alexander H |
Myristoylation of TMEM106B by NMT1/2 regulates TMEM106B trafficking and turnover |
poster |
|
Lazaro, Diana F |
Super-resolution microscopy reveals the molecular architecture of alpha-synuclein inclusions in model systems and human brain tissue |
poster |
|
LeBlanc, Kate |
Alternative splicing regulation by DIB-1 rescues tauopathy |
poster |
|
Lee, Eunju |
STING-driven epigenetic reprogramming of microglia and its role in Alzheimer's disease progression |
poster |
|
Lehtinen, Maria |
Contributions of choroid plexus to brain health and involvement in neurodegenerative disease |
talk |
|
Leibold, Noah |
ApoE isoform-dependent interaction with amyloidogenic pancreatic amylin |
poster |
|
Leija Salazar, Melissa I |
NeuroID—A CRISPR-based platform for functional and transcriptomic analysis of neurodegenerative disease genes |
poster |
|
Li, Cong |
TRPV1 promotes stress granule assembly and neurodegeneration in amyotrophic lateral sclerosis and frontotemporal dementia |
poster |
|
Li, Jixi |
MLKL regulates α-synuclein aggregates in Parkinson’s disease |
poster |
|
Liang, Zherui |
Studying APOE2 protective effects in Alzheimer's disease using integrative approaches and a novel mouse model |
talk |
|
Lipka, Joanna |
Developing a scalable human neuronal model to study Alzheimer’s disease tau pathology |
poster |
|
Lish, Alexandra |
CLU alleviates Alzheimer’s disease-relevant processes by modulating astrocyte reactivity and microglia-dependent synaptic density |
talk |
|
Liu, Yanru |
Investigating the function of TDP-43 in microglia |
poster |
|
Liu, Yingjun |
AAV-mediated direct in vivo CRISPR screening reveals common and selective neuronal vulnerabilities |
poster |
|
Lo, Chih Hung |
Lysosome-targeting acidic nanoparticles restore lysosomal acidification and rescue neuronal death in tauopathies |
poster |
|
Lodato, Mike |
Single-cell analysis of somatic mutation in human Parkinson's disease brain |
talk |
|
Loh, Peng Y |
Neurotrophic factor- α1 rescues memory loss and Alzheimer’s disease pathology |
poster |
|
Lou, Xuelin |
Targeting the NAD+ hydrolase to rescue synapse degeneration and cognition deficits of Alzheimer’s disease |
poster |
|
Lovchykova, Anastasiia |
Investigating the role of TMEM106B in FTLD-TDP |
poster |
|
Love, Cameron R |
The anti-siesta factor DAYWAKE prevents light-mediated lipid peroxidation in the brain |
poster |
|
Luo, Haichang S |
Sexually dimorphic mGluR5-GIRK signaling in the hippocampus and its response to soluble aggregates of amyloid β and α-synuclein |
poster |
|
Macosko, Evan |
Formation and function of interferon-responsive glia in remyelination |
talk |
|
Maglio Cauhy, Paula V |
Single-cell spatial transcriptomics reveals neuronal subtypes selectively vulnerable to tau pathology in a humanized MAPT knock-in mouse model expressing FTD-causing mutations |
poster |
|
McHugh, Tyne |
EIF4A1-dependent translation is a mediator of APOE2-driven synaptic regulation |
poster |
|
Miller, Jaeeun K |
A new paradigm—Determining the normal physiological function of APP and amyloid-beta in sleep |
poster |
|
Miranda, Maria del Pilar |
Single-cell analysis of brain lesion formation and reversal in a mouse model of mitochondrial neurodegeneration |
talk |
|
Mishra, Rachana |
Targeting TLX/NR2E1 to induce neurogenesis and improve cognition in Alzheimer’s disease mouse model |
poster |
|
Moallem, Elika Z |
Investigating cerebral metabolism following a TBI in an AD-relevant mouse model |
poster |
|
Montini, Federico |
GLP graded miR-30d ameliorate EAE by modulating microglia and is ready for human use |
poster |
|
Muhlhofer, Maria-Teresa |
Elevated brain legumain (LGMN) expression boosts TDP-43-like pathology in a progranulin (PGRN) deficient mouse model |
talk |
|
Mukadam, Aamir |
The antibody-TRIM21 interaction is required for effective immunotherapy and can be engineered for increased potency |
poster |
|
Murthygowda, Swetha B |
Early life social isolation accelerates ERV expression, glia-to-neuron TDP-43 pathological spread, and neurodegeneration in a Drosophila model |
talk |
|
Nair, Sudershana |
Single domain antibodies as therapy targeting pathological tau protein |
poster |
|
Narayan, Priyanka |
Decoding metabolic mechanisms of APOE4-mediated risk and identifying new pathways to protection |
talk |
|
Naseri, Nima N |
Specific phosphorylation patterns regulate isoform-dependent tau behavior |
poster |
|
Natarajan, Sahana |
Targeting complement receptor C3aR in 5XFAD model of Alzheimer's disease |
poster |
|
Nawaid, Hiba |
Establishing an LC-specific tauopathy mouse model to investigate early AD pathophysiology |
poster |
|
Neumann, Edwin N |
Development of a zinc finger CHARM epigenetic editor for human prion disease |
talk |
|
Neupane, Sandesh |
High-content arrayed dual CRISPRa and CRISPRo screening to identify genes regulating α-Synuclein aggregation |
poster |
|
Newton, Dwight F |
TDP43 proteinopathy leads to divergent cryptic splicing in the cortex and spinal cord |
poster |
|
Nguyen, Lien |
CASP8 intronic expansion identified by poly-glycine-arginine pathology increases Alzheimer’s disease risk |
talk |
|
O'Donoghue, Rachel |
Exploring the influence of the protective apolipoprotein E (APOE) variant, R251G, on the function of APOE-ε4 iPSC-derived microglia |
poster |
|
Ofengeim, Dimitry |
The interface of the adaptive and innate immune systems driving disease progression in the CNS |
talk |
|
Ogden, Pierce |
Brain shuttles to novel receptors to overcome liabilities of first-generation shuttled anti-amyloid therapeutics |
poster |
|
Okano, Hideyuki |
Identifying pre-symptomatic biomarkers in Parkinson's disease—Insights from transgenic marmosets |
talk |
|
O'Sullivan, Julia |
Human iPSC derived glial cells—What role do they play in inflammation in Alzheimer’s disease |
poster |
|
Owusu-Yaw, Bernie S |
Focused ultrasound-mediated disruption of the blood-brain barrier for improved delivery of AAV vectors to the brain |
poster |
|
Pao, Ping-Chieh |
A microfluidic-based device for modeling myelination in vitro |
poster |
|
Peikon, Ian D |
Functional iron deficiency in Parkinson's disease |
poster |
|
Peng, Chao |
Soluble protein post-translational modifications—A shared novel regulation mechanism for pathological protein transmission in neurodegenerative diseases with therapeutic potential |
poster |
|
Perez Arevalo, Andrea |
APOE4 microglia and their role in the pathogenesis of AD after traumatic brain injury (TBI)—Findings from an iPSC-human derived brain model |
poster |
|
Petrucelli, Leonard |
TDP-43 dysfunction—Disease insights and translational opportunities |
talk |
|
Pinals, Rebecca L |
Alzheimer’s disease risk triad drives perturbations in the global lipid economy of the brain and cerebrospinal fluid |
talk |
|
Podlesny-Drabiniok, Anna |
Regulation of disease-associated microglia and macrophages by MEF2C |
talk |
|
Powers, Alex E |
APOE4 alters lipid droplet metabolism in astrocytes |
poster |
|
Prajapati, Ravindra S |
Dissecting the mechanism of TDP-43 autoregulation |
poster |
|
Prigent, Alice |
Influence of extracellular amyloid-β pathology on intracellular α-synuclein and tau in a mouse model of Alzheimer's disease |
poster |
|
Prim, Courtney |
APOE traffics to lipid droplets in glial cells in an Alzheimer’s disease mouse model. |
poster |
|
Rani, Poonam |
Design and development of small-molecule-based human 20S proteasome activators, an emerging target in neurodegenerative diseases |
poster |
|
Rao, Chandrika |
iPSC-derived microglia reveal divergent TREM2 and TYROBP/DAP12 signaling pathways in late-onset Alzheimer’s disease |
poster |
|
Replogle, John |
A risk-associated coding variant in TMEM106B mediates its glycosylation, expression, and fibril formation |
talk |
|
Reyes, Charles Jourdan F |
X-linked dystonia-parkinsonism is a novel human tau astrogliopathy |
poster |
|
Ridley, Katherine |
Microglia determine ß-amyloid plaque burden but are non-essential for downstream pathology |
poster |
|
Rooklin, Rikki |
Reconstruction of a human blood-retina barrier to investigate the role of APOE variants in age-related macular degeneration |
poster |
|
Root, Jessica T |
Triglyceride biosynthesis modulates astrocytic function in an APOE allele specific manner |
poster |
|
Ryan, Veronica |
Altered mRNA transport and local translation in iPSC-derived neurons with RNA binding protein knockdown or ALS/FTD mutations |
poster |
|
Ryskeldi-Falcon, Benjamin |
Atomic pathology of ALS and FTD by cryo-EM of amyloid filaments |
talk |
|
Samaddar, Madhuja |
Lysosomal polyamine accumulation impairs lipid catabolism in ATP13A2 loss of function models |
poster |
|
Sapkota, Darshan |
A new variant of Aquaporin-4 modulates the pathophysiological functions of the water channel |
poster |
|
Schuldt, Braxton R |
TGF-β signaling drives APOE4 vascular dysfunction via a pro-fibrotic mechanism in mural cells |
poster |
|
Sebollela, Adriano S |
Molecular and cellular responses to β-amyloid peptide oligomers in human brain slice cultures |
poster |
|
Seker, Burcu F |
Mutated ABI3 causes vascular dysfunction in a mouse model of Alzheimer's disease |
poster |
|
Self, Wade K |
A gnotobiotic mouse model for characterizing the ability of human gut microbiota to modulate tau-mediated neurodegeneration |
poster |
|
Sepe, Sara |
Telomeric DNA damage response activation mediates Aβ42 oligomers toxicity in Alzheimer’s disease |
poster |
|
Seplovich, Gabriela G |
Differential effects of tau proteins on blood-brain barrier integrity |
poster |
|
Shakya, Rubina |
Melatonin alleviated methamphetamine-induced cognitive deficits through the canonical WNT signaling pathway in the mouse hippocampus |
poster |
|
Shan, Xiwei |
Neuronal models of AD Tauopathy reveal novel pathways modulating TAU aggregation |
poster |
|
Shan, Zoe |
Dissecting the impact of lipid asymmetry on glial ferroptosis |
poster |
|
Sharma, Nilesh |
Metabolic perturbation in ependymal cells leads to progressive peri-ventricular pathology and recapitulates Alzheimer’s disease pathogenesis |
poster |
|
Shi, Sophia M |
Cerebrovascular glycocalyx dysregulation during aging and neurodegenerative disease promotes blood-brain barrier dysfunction and brain bleeds |
poster |
|
Skuja, Lukas L |
The role of chronic NLRP3 inflammasome activation in the CNS |
poster |
|
Smeyers, Julie |
Defining consequences of loss of the ALS/FTD-associated kinase TBK1 on the proteome |
poster |
|
Soerensen, Maja Hoejvang |
Examining the spatial transcriptomic changes in the brain of a mouse model of TDP-43 proteinopathy |
poster |
|
Soung, Allison |
The transcription factor IRF8 governs microglia activation in neuroinflammatory conditions |
poster |
|
Stevens, Beth |
Functional interrogation of human microglial states in neurodegenerative disease |
talk |
|
Stirparo, Giuliano |
NETSseq reveals inflammatory and aging mechanisms in distinct cell types driving cerebellar decline in ataxia-telangiectasia |
poster |
|
Sun, Senmiao |
Neuronal and molecular regulation of mouse torpor |
poster |
|
Sun, Shuying |
CRISPR-Cas9 screens to identify genetic modifiers of C9ORF72-linked ALS/FTD |
poster |
|
Swift, Nathaniel A |
High-fat, high-sugar diet induces spatial memory deficits and apathy-like phenotype in APP/PS1 mice at 8-10 months of age |
poster |
|
Tabor, G. Travis |
Elucidating roles of DGAT-dependent microglial lipid droplet biogenesis in neurodegeneration |
poster |
|
Tahirovic, Sabina |
Endo-lysosomal dysfunction mediated by the loss of NPC1 leads to neurodegeneration |
talk |
|
Tang, Samantha X |
Exploring oligodendrocyte precursor cell-synapse interactions in Alzheimer's disease |
poster |
|
Teets, Emily |
Parkinson’s disease-linked genes act noncanonically in glia to prune neuron endings |
poster |
|
Tekverk, Daniel |
Novel and high-throughput assays for triaging inhibitors of emopamil binding protein |
poster |
|
Thomas, Christina M |
Tip60 neuroepigenetic HAT activator compounds as a therapeutic strategy for Alzheimer’s disease |
poster |
|
Thompson, Patrick |
Multi-modal investigation of epigenetic aberrations in human aging |
poster |
|
Tseng, Yi-Shuan |
Loss of energy homeostasis drives neurodegeneration |
poster |
|
Upreti, Chirag |
Circuit-level investigation of tau-mediated neurodegeneration in Alzheimer’s disease |
poster |
|
Van Alstyne, Meaghan |
Polyserine-mediated targeting of FAF2/UBXD8 ameliorates tau aggregation |
poster |
|
Vaquer-Alicea, Jaime |
Functional classification of tauopathy strains reveals the role of protofilament core residues |
poster |
|
Vasilkovska, Tamara |
The metabolic impact of ketogenic diet on Alzheimer’s disease |
poster |
|
von Maydell, Djuna |
Single-cell atlas of ABCA7 loss-of-function reveals impaired neuronal respiration via choline-dependent lipid imbalances |
poster |
|
Wang, Mark Xinyi |
Sodium oligomannate disrupts the adherence of Ribhigh bacteria to gut epithelia to block SAA-triggered Th1 inflammation in 5XFAD AD transgenic mouse |
poster |
|
Wang, Shijie |
Identification of modifiers of Parkin-dependent neurodegeneration using a CRISPR-KO screen |
poster |
|
Weitzman, Sarah |
Comparative analysis of H1 and H2 haplotypes in different cell types, ancestries, and diseases |
poster |
|
Winner, Beate |
Enteric nervous system—Key in disease initiation in Parkinson disease |
poster |
|
Wojda, Urszula |
MicroRNAs as biomarkers in neurodegenerative diseases—Focus on convergent signaling pathways |
poster |
|
Wu, Min |
Comprehensive characterization of alternative splicing mechanisms underlying learning at single neuron resolution |
poster |
|
Xie, Longxin M |
Targeting context-dependent interactors to restore TDP-43 splicing function in ALS |
poster |
|
Xu, Dongwei |
Understanding the mixed role of metformin in Alzheimer's disease |
poster |
|
Xu, Hong |
Targeting endogenous tau in seeded tauopathy models inhibits tau spread |
poster |
|
Xu, Huixin |
The choroid plexus synergizes with immune cells during brain inflammation and neurodegeneration |
poster |
|
Yamada, Kaoru |
Extracellular protein landscape during tauopathy in mice |
poster |
|
Yang, Cha |
TMEM106B deficiency does not induce TDP-43 aggregation in brain but leads to alterations in lipid metabolism and obesity in the TDP-43Q331K knock-in mouse model |
poster |
|
Yang, Xuyu |
Development of small molecules to replace neuroprotective protein, carboxypeptidase E as novel drugs to protect against oxidative stress induced cell death and neurodegeneration |
poster |
|
Yasuda, Yuga |
Japanese and Caucasian iPS cell models to address the racial differences in the effects of the APOE polymorphism on sporadic Alzheimer’s disease development |
poster |
|
Ye, Yingzhi |
CRISPRi screening identifies modifiers of TDP-43 loss-of-function-mediated neurotoxicity |
poster |
|
Yin, Jiang-An |
A genome-wide landscape of genetic modifiers of GCase deficiency revealed by an arrayed CRISPR activation screen |
poster |
|
Yip, Oscar |
CRISPR-KO screening for regulators of neuronal APOE expression |
poster |
|
Yuste Checa, Patricia |
Structure-guided functional dissection of the extracellular chaperone and apolipoprotein Clusterin (Apolipoprotein J) |
poster |
|
Zagare, Alise |
Analysis of insulin resistance as a risk factor for Parkinson’s disease |
poster |
|
Zeng, Jialiu |
Lysosome-acidifying nanoparticles rescue A30P α-synuclein induced neuronal death in cellular and animal models of Parkinson’s disease |
poster |
|
Zeng, Yi |
TDP-43 nuclear loss in FTD-ALS causes widespread alternative polyadenylation changes |
talk |
|
Zhang, Feng |
Exploration of biological diversity |
talk |
|
Zhang, Rui |
On the causal role of cerebrovascular glycocalyx degeneration in Alzheimer’s disease |
poster |
|
Zhao, Angela |
A gut feeling—Influence of gut microbiota on alpha-synuclein pathology in Parkinson's disease |
poster |
|
Zhu, Beika |
ADGRG1/GPR56 regulates protective microglial response in Alzheimer's disease |
talk |
|
Zhu, Yunlu |
Tau-mediated circuit dysfunction before cell death |
poster |
|
Zilberter, Misha |
Neuronal APOE4-induced early hippocampal network hyperexcitability in Alzheimer’s disease pathogenesis |
poster |
|
Zuccoli, Elisa |
Investigating α-synuclein aggregation in patient-specific immunocompetent midbrain organoids in Parkinson’s disease |
poster |
|
Zuchero, Joy |
Transport vehicle—Utilizing the brain vasculature to deliver neurodegenerative disease therapeutics |
talk |
|
Zuppe, Hannah |
Sex chromosomes and gonadal hormones contribute to lymphocyte responses in a mouse model of Alzheimer’s disease |
poster |