|
Presenting Author |
Abstract Title |
Talk/Poster |
|
Adamson, Brittany |
Interrogating the processes of genome editing with high-resolution functional genomics |
talk |
|
Almeida, Maira |
Short homology based CRISPR/Cas9 targeted integration for Cre/lox conditional gene inactivation tools in zebrafish |
poster |
|
Anzalone, Andrew |
Prime editing |
poster |
|
Ashoti, Ator |
A genome-wide CRISPR screen to identify modifiers of Dux4 cytotoxicity |
poster |
|
Banakar, Raviraj |
Genome engineering by homology directed repair mediated precise genome editing in plants |
poster |
|
Bassik, Michael |
Development of new CRISPR/Cas9-based tools to identify cancer drug targets and mechanisms of phagocytosis |
talk |
|
Bateup, Helen |
Genetically-engineered human brain organoid models of neurodevelopmental disorders |
talk |
|
Bergboer, Judith G |
TLA based targeted complete sequencing of CRISPR gene editing events; expected and unexpected findings |
poster |
|
Bestas, Burcu |
Improving the efficiency of precise knock-in for therapeutic genome engineering |
poster |
|
Bier, Ethan |
Lessons learned from neutralization drives |
talk |
|
Bofill De Ros, Xavier |
Systematic study of the structural determinants involved in Drosha cleavage fidelity |
poster |
|
Bondy-Denomy, Joseph |
Cas3 is for genomes, what Cas9 is for genes |
talk |
|
Bowden, Ramsay |
Comparing single versus dual guide RNA libraries to optimize focused CRISPR-Cas9 screen performance |
poster |
|
Bowen, Tyson |
Discovery and characterization of novel CRISPR associated proteins from non-pathogenic bacteria |
poster |
|
Brackett, Nicole F |
Gene editing the major cat allergen, Fel d 1, using CRISPR-Cas9 |
poster |
|
Carlson-Stevermer, Jared M |
CRISPR-Off—A tunable genome editing technology for control of on and off target editing efficiency |
poster |
|
Cereseto, Anna |
Allele specific repair of splicing mutations in cystic fibrosis through AsCas12a genome editing |
talk |
|
Chang, Andrew |
Mass cytometry and machine learning reveals cell population changes after CRISPR edits |
poster |
|
Chang, Ya-Ju |
Reversing macular degeneration by precise editing of risk SNPs in ARMS2/HTRA1 |
poster |
|
Chatterjee, Pranam |
Robust genome editing with broad-targeting CRISPR enzymes |
talk |
|
Chen, Sidi |
In vivo CRISPR screens in T cells and in GEMM models identified novel targets and biomarkers for immunotherapy |
talk |
|
Chen, You-Tzung |
Conservation of human MSI target mutants in an ICE CRIM mouse model |
poster |
|
Cheng, Ching-Wei |
Core facility for gene manipulation and knockout/knockin cell generation |
poster |
|
Clement, Kendell |
CRISPRLungo—Accurate quantification of complex genome editing events including large insertions and translocations |
poster |
|
Clement, Kendell |
NIST GEM—Genome editing metadata format as a standard to document and share genome editing data |
poster |
|
Coelho, Matthew |
CRISPR GUARD—Short guide RNAs protect off-target sites from Cas9 nuclease activity |
poster |
|
Collette, Nicole M |
Forensic analysis of Cas9 reveals cellular stress |
poster |
|
Conklin, Bruce |
Modeling therapeutic editing in patient-derived iPSC tissues |
poster |
|
Coomar, Seemon |
Exploring DCAF15 for reprogrammable targeted protein degradation |
poster |
|
Corbett, Sybilla |
The EMBL-EBI Genome Editing Catalogue |
poster |
|
Cuomo, Maria Emanuela |
Genome editing in immune cells for target validation and T cell reprogramming |
talk |
|
Daigle, Tanya L |
Suite of new genetic tools to access and probe the function of transcriptomically-defined cell types in the mouse brain |
poster |
|
Danner, Eric W |
Homology independent replacement of sequence |
poster |
|
de Onate Monje, Lorena |
Delivery of an endosomolytic CRISPR-Cas9 RNP via receptor-mediated endocytosis for cell-targeted genome editing |
talk |
|
Dhar, Beenish R |
Analysis of the role of H19 associated miRNAs in H19 function by
CRISPR/Cas9 gene editing |
poster |
|
Doench, John |
Genetic interaction screens with combinatorial CRISPR-Cas |
talk |
|
Donohoue, Paul P |
Enabling precision editing with CRISPR hybrid RNA-DNA guided Cas9 |
poster |
|
Du, Menghan |
Casilio-ME—Enhanced CRISPR-based DNA demethylation by RNA-guided coupling methylcytosine oxidation and DNA repair pathways |
poster |
|
Du, Menghan |
CRISPR artificial splicing factors |
poster |
|
Du, Menghan |
Split selectable markers |
poster |
|
Durham, Megan W |
Using CRISPR/Cas9 to identify oncogenic alternative splicing events in lung adenocarcinomas |
poster |
|
Dymek, Zachary W |
CRISPR/Cas9-mediated gene knockout to address primary hyperoxaluria |
talk |
|
Egli, Dieter |
Double strand break repair in the human preimplantation embryo |
talk |
|
Ellis, Nicole A |
Multiplex CRISPRi gene silencing identifies virulence-critical genes of the intracellular bacterial pathogen Legionella pneumophila |
poster |
|
Fehler, Olesja |
The differentiation analysis of ER-Hoxb8 cells modified via CRISPR/Cas9 |
poster |
|
Finkel, Yaara |
Developing a highly sensitive CRISPR based platform for virus and host functional genomics |
poster |
|
Foreman, Hui-Chen (Jane) C |
Engineering metagenomic Escherichia coli standard strains by CRISPR targeting of lacZ |
poster |
|
Fry, Lewis |
Guide RNA orientation influences SaCas9 and gRNA expression in a single vector designed for AAV-mediated gene editing |
poster |
|
Ganguly, Joyshree |
Unravelling the genetic accessibility and toolbox development for thermophilic Clostridia |
poster |
|
Gao, Caixia |
Genome editing with programmable nucleases in crop plants |
talk |
|
Gao, Yudong |
A “plug-and-play” solution for analyzing “omic” data using homology-independent universal genome engineering |
poster |
|
Gapp, Bianca |
Genetic screening to identify suppressors of Diamond-Blackfan anemia |
poster |
|
Gardiner, Jason L |
CRISPR-mediated DNA demethylation targeting in plants |
poster |
|
Gersbach, Charles |
Epigenome editing for gene therapy, cell programming, and functional epigenomics |
talk |
|
Ghoshal, Basudev |
Site specific CRISPR-based targeted DNA cytosine methylation in plants |
poster |
|
Grunewald, Julian |
CRISPR adenine and cytosine base editors with improved RNA off-target profiles |
poster |
|
Guan, Jingwen |
Characterization of the efficiency of CRISPR-Cas interference at the single-cell level |
poster |
|
Hamilton, Jennifer R |
Redesigning lentiviruses for the delivery of preassembled Cas9 ribonucleoprotein complexes |
talk |
|
Han, Kyuho |
Genome-wide CRISPR screens in lung cancer spheroids identify 3D growth specific cancer vulnerabilities |
poster |
|
Hanna, Ruth E |
Base editor screens to functionalize variants at scale |
talk |
|
Hanson, Britt |
The application of CRISPR/Cas9 for molecular correction therapy of neuromuscular disorders |
poster |
|
Hazelbaker, Dane Z |
A multiplexed gRNA piggyBac transposon system facilitates efficient induction of CRISPRi and CRISPRa in human pluripotent stem cells |
poster |
|
Hemphill, Kevin P |
Synthesis of a chemically modified MS2 guide RNA for use in CRISPR applications |
poster |
|
Henderson, Jordana |
mRNA expressing cytosine and adenine base editors efficiently mediate base corrections in vitro and in vivo |
poster |
|
Hess, Gaelen |
Targeted diversification via dCas9 mediated base editing |
poster |
|
Holden, Kevin |
An optimized, multi-guide RNA approach for generating gene knockouts more efficiently with CRISPR |
poster |
|
Hou, Zhonggang |
Introducing a spectrum of long-range genomic deletions in human embryonic stem cells using type I CRISPR-Cas |
talk |
|
Hsieh-Feng, Vicki R |
Improving grain yield of commercial rice cultivar through CRISPR/Cas9 |
poster |
|
Hummel, Aaron |
Genome editing in fresh produce crops for the consumer |
talk |
|
Iyer, Shruti V |
Understanding genetic variation in cancer using nanopore Cas9 targeted-sequencing (nCATS) |
poster |
|
Jacobi, Ashley |
Characterization of synthetic single guide RNAs for CRISPR/Cas9 genome editing—An extensive evaluation of gRNA formats, purity, and delivery methods |
poster |
|
Jauch, Saskia-Larissa |
Using CRISPR/Cas9 to analyze the regulation of S100A8/A9 in phagocytes |
poster |
|
Jiang, Yuan |
DNB-based on chip Motif Finding (DocMF) system—A high-throughput method to assay protein-DNA interactions |
poster |
|
Jin, Shuai |
Cytosine, but not adenine, base editors induce genome-wide off-target mutations in rice |
poster |
|
Joung, J. Keith |
Defining and improving specificities of gene-editing nucleases and base editors |
talk |
|
Kleinstiver, Ben P |
Broad and robust sequence targeting with novel CRISPR-Cas9 enzymes |
talk |
|
Konishi, Colin T |
Neuroediting—Modeling and correction of epilepsy mutations in patient-specific iPSCs through predictable and template-free CRISPR/Cas9 genome editing |
poster |
|
Koppes, Erik |
Swine models of human neurobehavioral disease |
poster |
|
Kulcsar, Peter |
Ranking between increased fidelity SpCas9 nucleases and target sites |
poster |
|
Kumar, Sanjay |
Facilitated genome editing in human induced pluripotent stem cells to advance disease modeling and screening |
poster |
|
Lamberth, Jacob |
Highly-efficient and -specific genome editing with Cas9 nickase ribonucleoproteins |
poster |
|
Lapinaite, Audrone |
Molecular mechanisms of programmable DNA base editors |
poster |
|
Lee, Jooyoung |
Tissue-specific control of Cas9 by microRNA-repressible anti-CRISPR proteins |
poster |
|
Lenter, Martin C |
Identification of essential genes of phagocytosis using pooled CRISPR knock-out screens and single-cell transcriptomics |
poster |
|
Leonetti, Manuel D |
Deep profiling reveals the complexity of integration outcomes in CRISPR knock-in experiments |
talk |
|
Li, Jinsong |
“Artificial spermatid”-mediated genome editing |
talk |
|
Li, Leyi |
CELLectro, a new method of CRISPR microinjection |
poster |
|
Li, Shiqian |
An improved auxin-inducible degron system with low basal degradation for endogenous human proteins |
poster |
|
Li, Songyuan |
Marker-free co-selection to improve base editing efficiency in human cells |
poster |
|
Li, Tingdong |
Domestication of wild tomato is accelerated by genome editing |
poster |
|
Li, Wei |
Linking genotypes with multiple phenotypes in single-cell CRISPR screens |
talk |
|
Liang, Puping |
Genome-wide profiling of adenine base editor specificity by EndoV-seq |
poster |
|
Liang, Xiquan |
A robust method for tagging endogenous genes through promoter trapping and short homology arms |
poster |
|
Lim, Donghyun |
A chemical conjugation platform for CRISPR-Cas9 |
poster |
|
Lin, Lin |
High-throughput characterization of cis- and trans- regulation of the human cytidine deaminase APOBEC3B |
poster |
|
Lin, Shu-Wha |
Investigation the mechanism of fibrosis in chronic kidney disease using a genetically modified mouse model |
poster |
|
Liu, Shawn |
Epigenetic editing to restore MeCP2 in Rett syndrome |
talk |
|
Lo, Shih-Ching Joyce |
CRISPR-mediated SOD1 gene disruption in vivo extends survival, blocks motor neuron loss and prevents motor function decline in ALS mouse model |
poster |
|
Long, Chengzu |
Correction of FENIB (familial encephalopathy with neuroserpin inclusion bodies) in iPSC-derived neurons through personalized base editing |
talk |
|
Long, Chengzu |
Modeling and correction of Hutchinson-Gilford progeria syndrome in patient-specific vascular smooth muscle cells and cynomolgus monkey via base editing |
poster |
|
Lopes, Rui |
PAX8 activates metabolic genes via enhancer elements in renal cell carcinoma |
poster |
|
Low, Benjamin E |
Precise, efficient knock-in of large transgenes into the mouse genome using a serine integrase |
poster |
|
Lu, Baisong |
Novel lentiviral capsid-based Cas9/sgRNA ribonucleoprotein (RNP) bionanoparticles for active transduction, transient expression and efficient gene editing |
poster |
|
Luedeman, Megan |
The impact of PARP inhibition on DNA polymerase θ-mediated end joining at Cas9-induced double-strand breaks |
poster |
|
Magnon, Veronica L |
CRISPR-mediated long noncoding RNA (lncRNA) editing for next generation therapeutics—A Precision Medicine Initiative |
poster |
|
Maragh, Samantha |
Update on the NIST Genome Editing Consortium |
talk |
|
Martinez-Galvez, Gabriel |
Where you cut matters—Reproducible MMEJ gene editing with MENTHU |
poster |
|
Mashimo, Tomoji |
Type I CRISPR-Cas3 mediated genome editing in human cells |
poster |
|
McDonough, Justin A |
Optimization of CRISPR/Cas12a editing and homology-directed repair in human stem cells |
poster |
|
McNeill, Matthew S |
CRISPAltRations—A validated CRISPR on/ off-target NGS quantification pipeline |
poster |
|
Meers, Chance |
DNA polymerase zeta drives RNA-mediated DNA modification |
poster |
|
Mehta, Kunal |
High-throughput genome engineering for industrial strain optimization |
poster |
|
Meijsing, Sebastiaan H |
Binding ≠ function—Linking glucocorticoid receptor binding to the regulation of genes in the endogenous genomic context |
poster |
|
Mendonca, Samir A |
In situ CAR T-cell generation through adenoviral vector gene transfer |
poster |
|
Mendoza, Brian J |
CASPER—CRISPR-Associated Software for Pathway Engineering and Research |
poster |
|
Mendoza, Brian J |
Identification of effective and conserved sgRNAs to combat Hepatitis B virus infection |
poster |
|
Mestiri, Imen |
Monitoring of CRISPR-Cas9 mediated gene editing events at the BRCA1 locus using molecular combing |
poster |
|
Mitra, Sheetal A |
Using Crispr-Cas9 technology to study biology and develop therapeutics for treatment of Ewing sarcoma |
talk |
|
Mizuno, Naoaki |
Intra-embryo large fragment exchange by CRISPR/Cas9-mediated genome editing with adeno-associated viral vector |
poster |
|
Montoya, Guillermo |
Conformational activation promotes CRISPR-Cas12a catalysis and resetting of the endonuclease activity |
talk |
|
Morell, Montse |
Detecting allele-specific genome editing outcomes using a fluorescence-based screening method |
poster |
|
Moreno-Mateos, Miguel A |
CRISPR-Cas13d in vivo RNA targeting to understand early embryogenesis |
poster |
|
Nakamae, Kazuki |
Detailed profiling with MaChIAto reveals various genomic and epigenomic features affecting the efficacy of MMEJ-assisted knock-in |
poster |
|
Naso, Gaetano |
CRISPR/Cas9-Mediated in situ correction of COL7A1 splice-site mutation hotspot |
poster |
|
Niakan, Kathy |
Using genome editing and single cell approaches to study early lineage specification in human embryos |
talk |
|
Omoto, Takashi |
Evaluation of the DNA cleavage activity of type I CRISPRs in human cells |
poster |
|
Petri, Karl |
ONE-seq—A highly adaptable and sensitive platform to detect gene editor off-targets |
poster |
|
Pfitzner, Chandran |
Evaluating zygotic and germline CRISPR-Cas9 gene drives in Mus musculus |
poster |
|
Pierce, Sarah |
The serine-threonine kinase LKB1 regulates chromatin accessibility in lung adenocarcinoma |
poster |
|
Pinello, Luca |
CRISPRitz—Rapid, high-throughput, and variant-aware in silico off-target site identification for CRISPR genome editing |
poster |
|
Porteus, Matthew |
Engineering cells with new biologic functions using genome editing |
talk |
|
Pugach, Pavel |
CRISPR/Cas9 based development of RNAi Rat Models for Drug Discovery |
poster |
|
Qian, Shu-Bing |
Programmable RNA N6-methyladenosine editing by CRISPR-Cas9 |
talk |
|
Rai, Pavandeep K |
Generation of USP15 knock out cell lines using Cas9-gRNA ribonucleoproteins to identify mechanisms involved in Parkinson’s Disease |
poster |
|
Ramsden, Dale A |
Incorporation of ribonucleotides during repair of Cas9-induced breaks by NHEJ |
talk |
|
Rath, Abhijit |
Functional interrogation of Lynch syndrome-associated MSH2 missense variants via CRISPR-Cas9 gene editing |
poster |
|
Rathbone, Tanner |
Non-viral delivery of crispr-cas9 for therapeutic gene editing in hepatocytes |
poster |
|
Replogle, Joseph |
Direct capture of CRISPR guides and multiplexed guide delivery enable massively scalable Perturb-seq |
poster |
|
Rettig, Garrett R |
High-throughput improvements to a complete strategy for discovery and characterization of on- and off-target CRISPR editing events via target enrichment and high-resolution NGS analysis |
poster |
|
Riesenberg, Stephan |
Almost absolute HDR of CRISPR induced DNA double-strand breaks by using a novel small molecule |
talk |
|
Rossi, Nicholas |
Predicting repair genotype of CRISPR-Cas9 mediated edits |
poster |
|
Roy, Kevin R |
Manipulating homology-directed repair for high-throughput precision genome editing |
poster |
|
Saada, Edwin |
Development and delivery of RNA-targeting CRISPR systems for anti-viral countermeasures—Manipulating host transcriptional regulation and degrading RNA-viral genomes |
talk |
|
Sashital, Dipali G |
Pervasive off-target and double-stranded DNA nicking by CRISPR-Cas12a |
talk |
|
Saunders, Thom |
Characterization of transgenic rats carrying CRISPR/Cas9 induced Cre recombinase knockins at the dopamine D1 and adenosine 2a receptor loci |
poster |
|
Schep, Ruben |
Chromatin context impact on CRISPR/Cas9 break repair pathway choice |
talk |
|
Schiel, John A |
Comparing the HDR efficiency of different repair templates using CRISPR-Cas9 and synthetic guide RNAs |
poster |
|
Schindele, Angelina |
Efficient induction of heritable inversions in plant genomes using the CRISPR/Cas system |
poster |
|
Schindele, Patrick |
Advancement of CRISPR/Cas mediated precise genomic modification techniques in Arabidopsis thaliana |
poster |
|
Schmierer, Bernhard |
The SciLifeLab High Throughput Genome Engineering facility—A competence centre for high throughput CRISPR/Cas applications |
poster |
|
Schrempf, Anna |
Novel insights into error-prone repair pathways of CRISPR-Cas9 induced DNA breaks |
poster |
|
Sheltzer, Jason |
Targeting cancer aneuploidy with CRISPR/Cas9 |
poster |
|
Sheri, Vijay |
Rice yield enhancement and nutritionally improved high-oleic acid sunflower through RNA guided genome editing (CRISPR-Cas9) |
poster |
|
Sherwood, Richard I. |
Predictable and precise template-free CRISPR editing of pathogenic variants |
talk |
|
Shih, Justin W |
Towards precise genome editing in rice through localized RNA repair templates and predictable indels |
poster |
|
Siksnys, Virginijus |
Exploring diversity of the Class 2 CRISPR-Cas nucleases |
talk |
|
Simone, Brandon W |
Expanding the CRISPR Toolbox with ErCas12a |
poster |
|
Singh, Avtar |
Optical pooled screens in human cells |
talk |
|
Sinha, Sanju |
A systematic genome-wide mapping of the oncogenic risks associated with CRISPR-Cas9 editing |
poster |
|
Sontheimer, Erik |
High-resolution structure of Cas9 in the catalytically poised state |
talk |
|
Spahn, Philipp N |
CRISPR/Cas9-mediated reversal of SNPs in DNA repair genes as a novel strategy to mitigate instability of cell factories used in biopharmaceutical manufacturing |
poster |
|
Sreekanth, Vedagopuram |
A genome editing platform for engineering of pancreatic endocrine cells |
poster |
|
Steinmetz, Lars M |
Developing technologies to enhance efficiency and precision of genome editing |
talk |
|
Sternberg, Samuel H |
Transposon-encoded CRISPR-Cas systems direct RNA-guided DNA integration |
talk |
|
Stevenson, Zach C |
Rapid self-selecting and clone free integration of transgenes into engineered CRISPR safe harbor locations in C. elegans |
poster |
|
Talas, Andras |
A fluorescent assay allows quick and easy measurement of DNA base editing efficiency |
poster |
|
Tambe, Akshay |
TAGE-display libraries for the discovery of in vivo gene editing biologics |
poster |
|
Tennant, Peter A |
Fluorescent in vivo editing reporter (FivER— A novel multispectral fluorescent reporter of in vivo genome editing |
poster |
|
Tsai, Shengdar |
Large-scale CHANGE-seq CRISPR-Cas9 profiling reveals genetic and epigenetic determinants of genome-wide nuclease activity |
poster |
|
Turk, Rolf |
Improved methods for CRISPR homology-directed repair using Alt-R HDR enhancer and ssDNA donors with optimized design |
poster |
|
Urnov, Fyodor |
Our genome-edited world—A data-based preview |
talk |
|
Usluer, Sunay |
Establishment and validation of IPSC lines with constitutive expression of dCas9 variants for CRISPRi |
poster |
|
Vakulskas, Christopher |
A high-activity mutant of A.s. Cas12a (Cpf1) that demonstrates high specificity and high activity over a broad range of temperatures, and site-to-site reliability that rivals S.p. Cas9 |
poster |
|
Valley, Hillary |
CFTR super exon partially corrects W1282X-CFTR |
talk |
|
Vidigal, Joana |
Correction of off-targeting in CRISPR screens uncovers genetic dependencies in melanoma cells |
poster |
|
Vonesch, Sibylle |
Towards a predictive understanding of donor DNA-directed precision editing outcomes across the genome |
poster |
|
Wang, Dan |
Gene delivery to non-human primate embryos using AAV aectors |
poster |
|
Wang, Xiao |
Efficient base editing in methylated regions with a human APOBEC 3A-Cas9 fusion |
poster |
|
Wang, Xuning |
CRISPR-DAV—CRISPR NGS data analysis and visualization pipeline |
poster |
|
Wei, Cindy T |
An in vivo investigation into the contribution of DNA binding and cleavage to on- vs. off-target discrimination by SpCas9 |
poster |
|
Wei, Wensheng |
Mapping functional elements at single amino acid resolution |
talk |
|
Weissman, Jonathan |
Single-cell-resolution lineage tracing of tumors in a mouse xenograft model reveals rapid and multidirectional metastasis |
talk |
|
Welker, Ervin |
Target contribution controls cleavage of SpCas9 target sequences with and without mismatches |
poster |
|
White, Malcolm F. |
Ring War—virus:host conflict involving type III CRISPR systems |
talk |
|
Wilde, Jonathan J |
A toolkit for the development of customized bioluminescent reporters of in vivo genome editing |
poster |
|
Wilson, Christopher J |
SaCas9 and AsCas12a (AsCpf1) are as potent and more specific than SpCas9 |
poster |
|
Wimberger, Sandra |
Modulation of the DNA damage response to enhance targeted integration at CRISPR/Cas9-mediated DNA double strand breaks |
poster |
|
Wu, Jiaqian |
Integrative analysis of lncRNA and transcription factor regulation in oligodendrocyte formation |
poster |
|
Wu, Wen-Hsuan |
CRISPR-based genome surgery for the treatment of autosomal dominant retinitis pigmentosa in a novel humanized mouse model |
poster |
|
Young, Joshua K |
RNA-guided double-stranded DNA target recognition and cleavage by miniature CRISPR-Cas endonucleases |
talk |
|
Zhang, Yu |
Enhanced CRISPR/Cas9 correction of Duchenne muscular dystrophy in mice by a self-complementary AAV delivery system |
poster |
|
Zhao, Yang |
In vivo liver-direct gene knockout using CRISPR/Cas9 technology |
poster |
|
Zhou, Qingxuan |
Small-molecule inhibitor and degrader of CRISPR-Cas9 |
poster |