Presenting Author |
Abstract Title |
Talk/Poster |
Agudelo, Daniel S |
Versatile in vivo genome editing with the prototypical Streptococcus thermophiles CRISPR1-Cas9 system |
poster |
Allen, Felicity |
Systematic analysis of CRISPR/Cas9-generated mutational profiles using synthetic self-targeting gRNA constructs |
poster |
Allen, Felicity |
JACKS—Joint Analysis of CRISPR/Cas9 Knockout Screens |
poster |
Aman, Rashid |
RNA virus interference via CRISPR/Cas13a system in plants |
poster |
Aregger, Michael |
Global mapping of metabolic genetic interaction networks using CRISPR-Cas screens |
poster |
Ata, Hirotaka |
Double-stranded break repair made predictable: single mutant allele predominates over any other by rational target selection in vivo |
poster |
Awah, Chidiebere |
Genome-wide CRISPR Cas9a knockout screen identifies biomarkers for predicting glioblastoma susceptibility to TOP2 poisons |
poster |
Bachle, Susanna |
CRISPR plasmid technology—Data and tool evolution trends from Addgene |
poster |
Bandyopadhyay, Anindya |
Enhancing plant breeding and product development by CRISPR systems |
poster |
Bassik, Michael |
Discovery of general and context-specific regulators of phagocytosis using magnetic genome-wide CRISPR screens |
talk |
Bello, Erica |
A CRISPR-scan assay for the functional characterisation of recurrent mutations in cancer |
poster |
Beying, Natalja |
SSB-induced homologous recombination in Arabidopsis thaliana |
poster |
Biswas, Kajal |
High-throughput BRCA2 variant analysis using mouse ES cell-based assay |
poster |
Bonafont Arago, Jose |
Novel efficient CRISPR/Cas9-based gene editing strategies for recessive dystrophic epidermolysis bullosa |
poster |
Boyle, Evan A |
Resolving core genes for cancer growth from high-throughput genetic screen data: applications from a co-functional gene network |
talk |
Brokowski, Carolyn E |
The ethical conduct of clinical trials involving novel genomic engineering tools |
poster |
Bruhn, Laurakay |
Improving CRISPR-Cas9 specificity with chemical modifications in single-guide RNAs |
poster |
Chang, Yong S |
Development of NTLA-1001—First-in-class, LNP-CRISPR/Cas9 mediated genome editing therapeutic for the treatment of ATTR |
talk |
Chen, Honglin |
Somatic genome editing in murine lung via AAV delivery of CRISPR |
poster |
Chen, Jia |
Base editing with a Cpf1–cytidine deaminase fusion |
poster |
Chen, Sidi |
Advances in multiplexed gene editing and in vivo genetic screening |
poster |
Chen, Wei |
Predicting the end-joining patterns of CRISPR/Cas9-mediated double stranded breaks from thousands of programmed sequences |
poster |
Chokshi, Chirayu |
Discovery and validation of genes essential for survival of recurrent Glioblastoma brain tumor initiating cells |
poster |
Chong, Shan |
Extracellular receptor-ligand interaction screening using CRISPR activation |
poster |
Choudhary, Amit |
Synthetic activators, inhibitors, and degraders of CRISPR-associated nucleases |
talk |
Ciccia, Alberto |
Modulating DNA repair to enhance precise genome editing |
talk |
Cogan, James Z |
Reprogramming the epigenome with next generation dCas9 fusions |
poster |
Conant, David F |
Methods for predicting repair genotype of CRISPR-Cas9 mediated edits |
poster |
Concordet, Jean-Paul |
Impact of DNA double strand break repair pathways on genome editing |
poster |
Conklin, Bruce |
Silent repair, a path to scarless genome surgery |
talk |
Connelly, Jon P |
Whole genome CRISPR-based KO screen to identify modulators of single strand templated repair |
poster |
Corda, Gabriele |
A knock-out genome-wide screen identifies novel potential therapeutic targets for the treatment of Friedreich’s ataxia |
poster |
Cox, Kurt |
High-throughput platforms to identify inhibitors of CRISPR-Cas9 |
poster |
Daboussi, Fayza |
One-step generation of multiple gene knock-outs in diatoms by DNA-free genome editing |
talk |
Dabrowska, Magdalena |
qEva-CRISPR—A method for quantitative evaluation of CRISPR/Cas-mediated genome editing in target and off-target sites |
poster |
D'Angelo, Michael E |
A new unbiased method for finding CRISPR off-target cut sites in live cells. |
poster |
Danner, Eric W |
Homology independent replacement of sequence |
poster |
Dao, Thi Mai Lan |
CRISPR-based approach for HBB gene correction in human CD34+ Hematopoietic stem cells |
poster |
Davidson, Alan R |
Crunching CRISPR—The many mechanisms of CRISPR-Cas inhibition by anti-CRISPRs |
talk |
de Onate, Lorena |
Liver tissue specific delivery and editing by receptor-mediated uptake of CRISPR-Cas9 |
poster |
Dede, Merve |
Identifying novel genomic vulnerabilities in human cancer cells through characterization of gene essentiality profiles |
poster |
Dersh, Devin |
Genome-wide CRISPR/Cas9 knockout screens identify regulators of MHC Class I in diffuse large B-cell lymphoma |
poster |
Desplan, Claude |
Evolution of sensory perception |
talk |
Dow, Lukas |
Optimized base editors enable efficient editing in cells, organoids, and mice |
poster |
Duringer, Alexis |
Identification and characterization of an S phase-specific degron with potential application to CRISPR-Cas9-based genome editing |
poster |
Edraki, Alireza |
A compact, high-accuracy Cas9 with a dinucleotide PAM for in vivo genome editing |
poster |
Enciso-Rodriguez, Felix E |
Overcoming self-incompatibility in diploid potato using genome editing |
poster |
Faure, Guilhem |
Mini CRISPR array, a weapon in phage wars |
talk |
Fellmann, Christof |
CRISPR-Cas9 circular permutants as programmable scaffolds for genome modification |
poster |
Finnigan, Gregory C |
Tuning CRISPR/Cas gene drives in budding yeast—Design, complexity, and inhibition |
poster |
Fraser, Hunter |
Functional genetic variants revealed by massively parallel precise genome editing |
talk |
Frock, Richard L |
Ku70 suppresses alternative end-joining in G1-arrested progenitor B cells |
poster |
Fuchs, Ryan |
In vitro characterization of Cas12a (Cpf1) endonucleases as tools for molecular biology |
poster |
Gallagher, Danielle N |
Single strand template repair—Characterization of a novel RAD51-independent pathway |
poster |
Gangopadhyay, Soumyashree A |
High-resolution spatiotemporal control of CRISPR-Cas9 using photocaged small molecules |
poster |
Gasior, Stephen |
Targeted gene activation with a type I CRISPR-Cas system in plants |
poster |
Ghanta, Krishna S |
5′ modifications improve potency, efficacy and tolerability of DNA donors for precision genome editing |
poster |
Gonatopoulos-Pournatzis, Thomas |
Development and application of novel CRISPR-based screens for investigating the regulatory and functional complexity of alternative splicing |
poster |
Grevet, Jeremy |
Domain-focused CRISPR-Cas9 screen identifies HRI kinase as a regulator of fetal hemoglobin in adult human erythroid cells |
talk |
Gu, Bin |
Efficient generation of targeted large insertions by microinjection into two-cell stage mouse embryos |
talk |
Guo, Haotian Q |
All-or-none responses of Csy4 to the substrate's flanking sequences and machine learning of the selection rules |
poster |
Gurskaya, Nadya |
Modelling epidermolysis bullosa simplex with CRISPR/Cas/9 system |
poster |
Gurumurthy, Channabasavaiah B |
In vivo germ-line genome editing in rodents |
talk |
Haapaniemi, Emma M |
CRISPR-Cas9 induces a p53-mediated DNA damage response |
talk |
Haining, Nicholas |
In vivo genetic screens to discover targets for cancer immunotherapy |
talk |
Haurwitz, Rachel |
Precision genome editing—Identification of highly efficient and specific guides for CRISPR-Cas9 gene editing at human T cell loci |
talk |
He, Jiankui |
CRISPR Off-target analysis in human embryo |
poster |
Heffel, Matthew G |
Computational modeling of tunable CRISPR gene drive population dynamics |
poster |
Hess, Gaelen |
Targeted diversification via dCas9 mediated base editing |
poster |
Heyza, Joshua R |
Mechanisms of resistance to interstrand crosslinks with ERCC1 deficiency |
poster |
Hidalgo Cantabrana, Claudio |
Repurposing the endogenous CRISPR-Cas I-E system for genome editing in Lactobacillus crispatus |
poster |
Holden, Kevin |
Inference of CRISPR Edits (ICE)—A free, online analysis tool for multiplex CRISPR edits |
poster |
Huang, Jeffrey Y |
Developing CRISPR-Cas9 knock-in models of rare pediatric disorders to better characterize pathogenesis and evaluate novel therapeutics |
poster |
Hulton, Chris |
A CRISPR-Cas9 system for direct genome editing in lung cancer patient-derived xenografts |
poster |
Ivanova, Marianna |
Phenotype and genotype characterization of Usher syndrome in Russian cohort |
poster |
Iyer, Shruti V |
CATCH me if you can—Characterization of BRCA1 structural variation using HLS-CATCH system and nanopore sequencing |
poster |
Jacobi, Ashley |
A comprehensive study comparing on- and off-target levels of the most common forms of CRISPR/Cas9 guide RNAs |
poster |
Jacobs, Thomas B |
High-throughput functional genomics in plants with pooled, combinatorial CRISPR screens |
poster |
Jensen, Emil D |
Directed evolution with Cas9 and error-prone donor-coupled gRNA delivery |
poster |
Jensen, Michael K |
Toolkits for multiplex CRISPR/Cas-mediated genome engineering, transcriptional reprogramming, and directed evolution in yeast |
poster |
Jiang, Tingting |
In-vivo adenine base editing rescues disease phenotype in an adult mouse model of tyrosinemia |
poster |
Jinek, Martin |
Structural insights into the mechanism of DNA cleavage by CRISPR-Cas12a/Cpf1 |
talk |
Johnston, Robert K |
Rapid electrochemical detection and quantification of Cas9 protein |
poster |
Jones, Stephen K |
High-throughput profiling of DNA binding by engineered high-fidelity Cas9 variants |
poster |
Joung, J. Keith |
Enhanced CRISPR-Cas12a variants with increased targeting ranges and activities for gene, epigenetic, and base editing |
talk |
Karlseder, Jan |
Regulation of DNA repair pathway choice in S/G2 by the NHEJ inhibitor CYREN |
talk |
Kato, Tomoko |
Genome editing via Cas9 RNP improves the HDR/NHEJ ratio |
poster |
Kelliher, Timothy |
Genome editing in diverse crops and varieties via haploid induction |
poster |
Keough, Kathleen |
ExcisionFinder—A software tool for personalized and allele-specific sgRNA design via incorporation of genetic variants |
poster |
Kleinstiver, Ben P |
Enhanced activity and targeting range CRISPR-Cas12a variants for genome, epigenome, and base editing |
poster |
Kulcsar, Peter |
Ranking between high fidelity SpCas9 nucleases |
poster |
Kunii, Atsushi |
Three-component repurposed technology for enhanced expression (TREE)—Highly accumulable transcriptional activators via branched tag arrays |
poster |
Lazzarotto, Cicera R |
CHANGE-seq—A high-throughput method for defining CRISPR-Cas9 genome-wide activity in vitro |
poster |
Lee, Hye Young |
Nanoparticle delivery of CRISPR into the brain rescues a mouse model of fragile X syndrome from exaggerated repetitive behaviors |
talk |
Leger, Brittany S |
A synthetic gene drive with small-molecule contingency |
poster |
Lenoir, Walter F |
Visualization tools of genetic interactions interpreted through genetic fitness screens |
poster |
Li, Wei |
Identification of essential sites in the CTCF and FOXA1 cistromes using CRISPR screens |
talk |
Lin, Shu-Wha |
Use of Quick Macro to increase efficiency when designing sgRNA for Cas9 |
poster |
Lippman, Zachary |
Gene editing in plants is here. Now what? |
talk |
Liu, David R |
Base editing—Chemistry on a target nucleotide in the genome of living cells |
talk |
Lu, Baisong |
Delivering Cas9 mRNA by lentivirus-like particles for transient expression and efficient gene editing |
talk |
Lu, Quinn |
Strategies for controlling off-target effects and biological variations in CRISPR/Cas9 genome editing experiments |
poster |
Luttgeharm, Kyle D |
Automating CRISPR mutation detection and zygosity determination |
poster |
Ma, Tao |
Genetic suppression of the kinase activity for mRNA translational factor eEF2 alleviates cognitive and synaptic impairments in a mouse model of Alzheimer’s disease |
poster |
Machado, Hidevaldo B |
Gene knockout or gene activation screening with arrayed synthetic CRISPR libraries |
poster |
Maguin, Pascal |
S. pyogenes type II-A CRISPR-cas system provides limited protection against Kayvirus phages |
poster |
Mair, Barbara |
Mapping genetic dependencies in human embryonic stem cells by genome-wise CRISPR screening |
poster |
Makarova, Kira |
Functional prediction and evolution of Class 2 CRISPR-Cas systems |
talk |
Marson, Alexander |
Reprogramming human T cell circuitry with CRISPR |
talk |
Martyn, Gabriella E |
Naturally occurring mutations disrupt binding of fetal globin repressor to elevate fetal hemoglobin |
talk |
McCaffrey, Anton |
CleanCap allows diverse 5’ cap modifications—The RNA epitranscriptome |
poster |
McDonough, Justin A |
Improving homology-directed repair efficiency in human stem cells |
talk |
McNeill, Matthew S |
The novel Alt-R® CRISPR HDR Design Tool for ssDNA homology-directed repair template design |
poster |
Mir, Aamir |
Heavily and fully modified RNAs guide efficient Cas9-mediated genome editing |
poster |
Miyaoka, Yuichiro |
Modified interactions between Cas9/Cas9 D10A nickase and genomic DNA enhances HDR |
poster |
Molla, Kutubuddin A |
Multiplex CRISPR-mediated base editing in rice |
poster |
Morell, Montserrat |
Screening successful homologous recombination events using a fluorescence-based method |
poster |
Morgens, David W |
CRISPRi interaction map and targeted mutagenesis identify first-in-class mechanism of antiviral, retrograde trafficking inhibitors |
poster |
Nakade, Shota |
Biased genome editing using the LoAD (local accumulation of DSB repair molecules) system |
poster |
Nelson, Christopher E |
Long-term evaluation of genome editing outcomes for Duchenne muscular dystrophy |
poster |
Ohtsuka, Masato |
Development of a reporter mouse model suitable for evaluation of in vivo genome editing efficiency |
poster |
Olson, Eric |
Correction of Duchenne muscular dystrophy by genome editing |
talk |
Pellegrino, Enrica |
Engineering a drug-inducible allelic series in human stem cells |
poster |
Perez-Bermejo, Juan A |
Interaction proteomics and genome engineering unravel how BAG3 gene variants cause heart disease |
poster |
Peters, Samuel T |
Optimizing genome editing rates with RNP delivery of CRISPR-Cas9 reagents |
poster |
Petris, Gianluca |
AsCpf1 genome editing rescues cystic fibrosis splicing mutation 3272-26A>G in patient organoids |
poster |
Pickar-Oliver, Adrian |
Targeted gene activation with type I CRISPR-Cas systems in mammalian cells |
talk |
Potter, Jason |
Improved TALENS for editing in PAM deserts |
poster |
Preece, Roland |
CRISPR-CAR lentiviral vector coupling transgene expression with targeted scission for the engineering of universal T cells |
poster |
Rees, Holly A |
Characterizing and improving the specificity and applicability of base editing |
poster |
Rettig, Garrett R |
A complete strategy for characterizing on- and off-target CRISPR/Cas9 editing events via target enrichment and high-resolution NGS analysis |
poster |
Riesenberg, Stephan |
Efficient multiplexed precise genome editing of human pluripotent stem cells by modified DNA-dependent protein kinase catalytic subunit |
poster |
Romanienko, Peter J |
Fine tuning of electroporation of CRISPR reagents into mouse embryos |
poster |
Rousseau, Beth A |
Programmable RNA recognition and cleavage by N. meningitidis CRISPR-Cas9 |
talk |
Rowe, Matthew H |
Streamlined production, application, and analysis of pooled genome-wide sgRNA lentiviral libraries |
poster |
Roy, Kevin R |
MAGESTIC—A platform for multiplexed CRISPR-HDR variant engineering and tracking at the genome-scale |
poster |
Russell, Alasdair |
Allele-specific curative editing of patient-derived iPSCs |
poster |
Sadelain, Michel |
T cell and stem cell editing for cancer immunotherapy |
talk |
Saunders, Thom |
CRISPR/Cas9 genome editing pipeline for mice and rats |
poster |
Savage, David |
Directed evolution of smaller CRISPR-Cas proteins using MISER |
talk |
Schimmel, Joost |
Exploiting DNA repair knowledge in genome editing approaches |
poster |
Schwank, Gerald |
Correction of autosomal recessive disorders via CRISPR-associated base editors in adult animals |
poster |
Seth, Meetu |
Rapid and specific purification of Cas9-RNP from mammalian cells and tissues |
poster |
Sheltzer, Jason |
CRISPR/Cas9 mutagenesis invalidates multiple genetic targets undergoing clinical trials in cancer |
poster |
Shen, Max W |
Predictable and precise template-free editing of pathogenic mutations by CRISPR-Cas9 nuclease |
poster |
Shih, Justin W |
Phylogenetic and evolutionary analysis of DNA repair gene families in plants |
poster |
Stark, Jeremy |
Mechanisms of intrachromosomal deletion rearrangements, and other chromosomal break repair outcomes |
talk |
Stonebloom, Solomon |
High-throughput genome engineering for industrial strain optimization |
poster |
Symington, Lorraine |
Sequence context influences mutagenic repair of CRISPR/Cas9-induced double-strand breaks |
talk |
Talas, Andras |
Sequence specificity of Cas9 variants |
poster |
Temesgen, Ayantu M |
Employing the CRISPR-Cas9 technology to develop robust and high throughout degradation assays |
poster |
Tran, Mai H |
Cpf1 proteins excise CRISPR RNAs from mRNA transcripts in mammalian cells |
poster |
Tran, Ngoc Tung |
The efficient CRISPR/Cas9-based gene editing of FANCG locus in human hematopoietic stem cells: a potential gene therapy Fanconi anemia |
poster |
Trinh, Cong T |
CASPER—A platform for developing effective CRISPR-Cas targets |
poster |
Tsai, Yi-Ting |
CRISPR-based genome surgery for the treatment of autosomal dominant retinitis pigmentosa |
poster |
Tsang, Stephen H |
CRISPR-based genome surgery for the treatment of autosomal dominant retinitis pigmentosa |
poster |
Turk, Rolf |
Improved genome editing efficiency in CD34+ cells using single-stranded oligonucleotides |
poster |
Tycko, Josh |
High-resolution CRISPR-Cas9 screen identifies constituent functional elements within enhancers and loop anchors |
talk |
Vakulskas, Christopher |
Improved CRISPR-SpCas9 and -AsCas12a proteins mitigate off-target risk and improve on-target performance and reliability |
poster |
Varble, Andrew |
Recombination between phages and CRISPR-cas loci disseminates immunity during infection |
talk |
Villiger, Lukas T |
Treatment of a metabolic liver disease by in vivo genome base editing in adult mice |
poster |
Voytas, Daniel F |
Genome editing and plant agriculture |
talk |
Walia, Rupali |
Designing innovative cell culture models to study chronic wasting disease by precise gene replacement using the CRISPR toolbox |
poster |
Walter, David |
CRISPR-Cas9—A versatile tool for identifying and validating synthetic lethal interactions |
poster |
Walter, Marius |
Gene drive in herpesviruses |
talk |
Wang, Alan S |
Identification of proteins at genomic loci |
poster |
Wang, Chia-Lin |
CRISPR/Cas9 based development of RNAi rat models for drug discovery |
poster |
Wefers, Benedikt |
Optimizing CRISPR/Cas9-mediated gene targeting in mice for disease modelling |
poster |
Wheatley, Matt |
CRISPR/Cas9-enabled multiplex genome editing in Magnaporthe oryzae |
poster |
Wienert, Beeke |
Discovery of in situ CRISPR-Cas off-targets by chromatin-immunoprecipitation of DNA repair factors |
poster |
Wilde, Jonathan J |
Efficient zygotic genome editing via RAD51-enhanced interhomolog repair |
talk |
Will, Anja J |
Enhancer composition and dosage control developmental gene expression. |
poster |
Woltjen, Knut |
Precise human disease allele creation and correction through microhomology-mediated end joining |
talk |
Wong, Tatianna Wai Ying |
Utilization of CRISPR/Cas9-based gene editing to restore the open reading frame in a novel DMD mouse model |
poster |
Wood, Andrew |
How chromatin modifications influence CRISPR-Cas9 mutation frequency and the outcome of mutagenic DNA repair |
poster |
Worley, Jeremy |
Identifying the molecular determinants of poor outcome in colon adenocarcinoma using VIPER and pooled single-cell CRISPR screening |
poster |
Wyman, Stacia K |
Indel-based barcoding to track cellular engraftment of CRISPR-edited primary cells |
poster |
Yang, Li |
Genome editing pinpoints single bases |
poster |
Yeo, Gene W |
RNA modulation by CRISPR/Cas proteins |
talk |
Yoon, Mijung |
Targeted base editing via RNA-guided cytidine deaminases in Xenopus laevis embryos |
poster |
Yourik, Paul |
Kinetic comparison of Cas9 homologs |
poster |
Zhang, Hanrui |
Genome-wide CRISPR screen in primary macrophages for discovery of novel regulators of macrophage efferocytosis |
poster |
Zhang, Jenny |
Discovery of an anti-CRISPR protein that unlocks novel anti-CRISPR loci in diverse bacteria |
talk |
Zhang, Ning |
Generation and characterization of tomato lines with CRISPR/Cas9-mediated mutations in candidate immunity-associated genes |
poster |