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Presenting Author
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Abstract Title
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Talk/Poster
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Adamson, Brittany
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Perturb-seq—A multiplexed single-cell CRISPR screening platform
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talk
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Agudelo, Daniel S
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Marker - free co-selection for CRISPR-driven genome editing in human cells
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poster
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Alcott, Callison E
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A druggable genome screen identifies treatment targets for Rett and MECP2 duplication syndromes
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poster
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Antony, Jisha
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Role of cohesin mutations in myeloid leukemia
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poster
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Aregger, Michael
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Global mapping of metabolic genetic interaction networks using CRISPR-Cas9 screens—A roadmap for therapeutic discovery
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poster
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Bae, JiHyun
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Multiple sgRNAs with overlapping sequences enhance CRISPR/Cas9-mediated knock-in efficiency
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poster
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Baeumler, Toni A
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Engineering synthetic signalling pathways with programmable dCas9-based chimeric receptors
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poster
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Baker, Candice N
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Efficiently creating and validating mouse models using CRISPR/Cas9
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poster
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Bandyopadhyay, Anindya
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Successful application of CRISPR-CPF1 in rice
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poster
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Bhowmik, Pankaj K
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The CRISPR/Cas system for haploid plant cells—Challenges and progress of wheat genome editing using microspores
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talk
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Bier, Ethan
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The many flavors of active genetics
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talk
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Bikou, Maria
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Functional analysis of PIEZO1 using genome edited hiPSC-derived cardiomyocytes as a model system
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poster
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Billmann, Maximilian
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Genome-wide identification of genetic interactions in human cells using CRISPR/Cas9
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poster
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Bolukbasi, Mehmet F
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Cas9-Cas9 fusions provide a versatile genome editing platform
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poster
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Bondy-Denomy, Joseph
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Inhibition of CRISPR-Cas9 with bacteriophage proteins
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talk
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Brito, Luciano A
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Lack of E-cadherin during zebrafish craniofacial development and implications for orofacial cleft etiology
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poster
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Brokowski, Carolyn E
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Scientific, ethical, & legal considerations in reviewing CRISPR the disruptor
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poster
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Brunet, Anne
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The African killifish—A new vertebrate model to study aging and age-related diseases
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talk
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Buerckstuemmer, Tilmann
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A scalable approach towards conditional gene inactivation based on artificial introns
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poster
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Burt, Austin
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Modified mosquitoes for malaria control—Current status, requirements for success, and a step-wise approach for getting there
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talk
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Carette, Jan
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Genetic knockout screens to study virus host interactions
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talk
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Casini, Antonio
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Directed evolution of highly specific SpCas9 variants
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poster
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Champer, Jackson
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CRISPR gene drives with reduced resistance potential
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talk
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Chaverra Rodriguez, Duverney D
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Targeted delivery of CRISPR/Cas9 into the adult mosquito germline
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poster
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Chen, Fuqiang
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Chromatin interacting protein domains improve gene editing efficiency of class 2 CRISPR-Cas effector endonucleases on endogenous targets in the human genome
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poster
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Chen, Jia
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An enhanced base editing system
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poster
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Cheng, Albert W
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Casilio—A modular platform for combinatorial (epi)genome editing and chromatin imaging
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talk
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Choudhary, Amit
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Small molecule inhibitors and activators of CRISPR-Cas9
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talk
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Ciccia, Alberto
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CRISPR-mediated base editing enables efficient disruption of eukaryotic genes through induction of STOP codons (iSTOP)
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talk
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Conklin, Bruce
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Genome engineering human iPS cells to model and treat disease
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talk
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Cook, Peter J
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Rapid ex-vivo and in-vivo modeling of brain cancer-associated genomic rearrangements
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talk
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Corbett, Sybilla
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The EMBL-EBI CRISPR archive
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poster
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Cotta-Ramusino, Cecilia
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Characterization of genomic rearrangements in response to CRISPR/Cas9-induced double-strand breaks
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talk
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Crawford, Emily D
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Using targeted nucleases to enhance discovery and detection by deep sequencing
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poster
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Cuomo, Emanuela
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A predictive approach to ‘On-Target’ drug resistance in oncogenic cellular models
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poster
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Dalal, Sorab
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Generation of transgenic mice using sperm mediated gene transfer.
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poster
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Daley, Timothy P
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Mixture models for estimating effect sizes in genome-wide CRISPRa/i screens
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poster
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D'Angelo, Michael E
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CRISPR/Cas9 genome edited models of STAT3 activated lysosome mediated cell death in mammary epithelial cells
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poster
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Danner, Eric W
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Knock-in strategies for gene therapy—Utilizing the non-homologous end joining repair pathway
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poster
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Das, Sunny
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Targeting the macrosatellite repeat D4Z4 to develop therapeutic tools for Facioscapulohumeral muscular dystrophy
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poster
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Datlinger, Paul
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CROP-seq—Pooled CRISPR screening with single-cell transcriptome readout
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talk
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Dorkin, Joseph R
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Enhanced in vivo gene editing efficiency with single dose administration of CRISPR-Cas9 components formulated in proprietary lipid nanoparticles
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talk
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Dowdy, Christopher R
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C57BL/6NCrl mouse models generated by CRISPR/Cas9-mediated gene-editing
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poster
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Doyle, Riley O
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Evaluation of predictors of guide RNA performance across cell lines and species
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poster
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Enciso, Felix E
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Overcoming self-incompatibility in diploid potato using genome editing
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poster
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Fan, Meng-Ni
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Generation and application of MHC class I null immunodeficient mice with bleeding disorder
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poster
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Fan, Yong
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Engineering TALENs specific targeted to mutant mitochondrial genomes leaving nuclear genome untouched
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poster
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Feng, Weiran
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BRCA2 suppresses replication stress-induced mitotic and G1 abnormalities through homologous recombination
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talk
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Ferry, Quentin RV.
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Rational design of inducible CRISPR guide RNAs for de novo assembly of transcriptional programs
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poster
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Gallagher, Danielle N
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CRISPR/Cas9 genome editing—Characterization of a Rad51-indepdendent DNA repair pathway
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poster
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Gao, Huirong
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Progress on applications of CRISPR-Cas enabled advanced breeding technology in trait development in maize
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talk
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Garcia Lopez, Jesus
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Modeling high risk neuroblastoma through CRISPR/CAS9 genome editing
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poster
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Garyfallos, Dimitrios
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Functional genomic studies of myeloid leukaemias using in vitro and in vivo CRISPR/Cas9 forward genetics screens
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poster
|
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Gauttam, Rahul
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A dual-inducible CRISPR Interference system for the redirection of metabolic fluxes in Corynebacterium glutamicum
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poster
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Georgiadis, Christos
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Homogenous T cell engineering using novel CRISPR-CAR coupled lentiviral vector platform
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talk
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Gersbach, Charles
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Genome and epigenome editing for gene therapy and cell programming
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talk
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Gibb, Bryan
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Protein dynamics of human RPA and RAD51 on ssDNA during assembly and disassembly of the RAD51 filament
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poster
|
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Gilbert, Luke
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Towards a genetic interaction map of the human cell
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talk
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Gisler, Santiago
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Regulatory elements associate with frequency of CRISPR-Cas9 induced insertions, but not deletions, in mouse embryonic stem cells
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poster
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Guay, David
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Peptide technology to deliver CRISPR ribonucleoprotein in therapeutic cells
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talk
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Gurumurthy, Channabasavaiah B
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CRISPR solution for creating Cre-LoxP genetics resources
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poster
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Haber, James
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Rad51-independent single-strand template repair of site-specific double-stand breaks
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talk
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Haeussler, Maximilian
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CRISPOR.org supports the whole process of genome editing
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poster
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He, Jiankui
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Evaluating the safety of germline genome editing in human, monkey and mouse embryos
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talk
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Heidenreich, Matthias
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Multiplex gene editing by CRISPR-Cas and Cpf1 in the mouse brain
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talk
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Hellebaut, Lana
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Gene targeted insertion of the AP-MS tag in plant cells using CRISPR/Cas9
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poster
|
|
Holden, Kevin
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Use of synthetic sgRNAs for highly efficient CRISPR editing in various cell types
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poster
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|
Hsu, Jonathan Y
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CRISPR-SURF—An integrative and streamlined pipeline for analysis of CRISPR-based non-coding tiling screens
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talk
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|
Huangfu, Danwei
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Investigating human development through genome editing in pluripotent stem cells
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talk
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Humphryes-Kirilov, Neil A
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Thera-Seq—A high-throughput deep sequencing approach for preclinical CRISPR off-target assessment
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poster
|
|
Hynes, Richard
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National Academies report on Human Genome Editing—Conclusions, questions and follow-up
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talk
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|
Jacobi, Ashley
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Optimized design, modification, and delivery of the Acidaminococcus sp. Cpf1-gRNA ribonucleoprotein complex
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poster
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|
Jaenisch, Rudolf
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Epigenetics, stem cells and disease research
|
talk
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Jakimo, Noah
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Chimeric CRISPR guides enhance Cas9 target specificity
|
poster
|
|
Jang, Yoo Jin
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High efficient genetically modified mice generation with Campylobacter jejuni Cas9
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poster
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|
Jost, Marco
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Combined CRISPRi/a-based chemical genetic screens reveal that rigosertib is a microtubule-destabilizing agent
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talk
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|
Kao, Winston W
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Gene therapy of mucopolysaccharidosis type VII (MPS VII) with CRISPR/Cas9 genome editing
|
poster
|
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Kim, Sang Yong
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Method for CRISPR-Cas9 gene-editing in egg cells incorporating predictive success
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poster
|
|
Klann, Tyler S
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CRISPR–Cas9 epigenome editing enables high-throughput screening for functional regulatory elements in the human genome
|
poster
|
|
Kocak, Daniel D
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Increasing specificity of CRISPR-Cas systems using RNA secondary structure
|
poster
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|
Koonin, Eugene
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Mobile genetic elements and evolution of CRISPR-Cas systems—Both cas genes and spacers come from the mobilome
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talk
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|
Kosicki, Michal
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Allelic diversity introduced by Cas9
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poster
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|
Kousholt, Arne Nedergaard
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Developing a CRISPR-CAS9 functional assay approach to classify BRIP1/FANCJ gene variants of uncertain significance
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poster
|
|
Kulcsar, Peter Istvan
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Crossing enhanced and high fidelity SpCas9 nucleases
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poster
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|
Le, Thi Thanh Huong
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Application of gene therapy for Rett syndrome
|
poster
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|
Lee, Eun-Seo Ency
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In vivo high-throughpu profiling of CRISPR–Cpf1 activity
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poster
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Lee, Jae Hoon
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The PTC-containing mRNAs in the engineered nuclease-mediated knockout mice
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poster
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Lee, Yoon Hoo
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Generation of simultaneous inversion and knock-in based hemophilia mouse model using CRISPR/Cas9
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poster
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Legube, Gaelle
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Chromatin and chromosome dynamics during DNA double strand break repair
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talk
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Leonetti, Manuel D
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Highly specific gene knock-in using long single-stranded DNA donors in human cells
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talk
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Lim, Kayeong
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Genome-wide target specificities of CRISPR RNA-guided programmable deaminases (Assessing and improving the target specificities of CRISPR-mediated base editing)
|
poster
|
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Lin, Yingbo
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High throughput arrayed CRISPR-Cas9 screening for genes involving in IGF-1R SUMOylation dependent cell growth
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poster
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Liu, David R
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Base editing—Genome editing without double-stranded DNA cleavage
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talk
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Long, Chengzu
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Genome editing to model and treat familial dilated cardiomyopathy
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poster
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Lukyanchikova, Varvara
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Directed modifications in structure of topologically associating domains in mice by CRISPR/Cas9-mediated editing
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poster
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Luttgeharm, Kyle D
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Automating CRISPR mutation detection and zygosity determination
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poster
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Mabuchi, Meg
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In vitro characterization of Cpf1 endonucleases as tools for molecular biology
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poster
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Machado, Hidevaldo B
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Chemical modifications of synthetic guide RNA for enhanced RNA stability and reduced cellular toxicity in CRISPR-Cas9 genome editing
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poster
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Mahiou, Jerome
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A CRISPR/Cas9 based gene editing platform to create cell lines expressing CFTR variants from the native gene locus and compatible with functional assay
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poster
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Maino, Eleonora
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Exploring the therapeutic potential of CRISPR/Cas9 technology for the treatment of MeCP2 duplication syndrome
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poster
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Marco, Eugenio
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UDiTaS™—A streamlined genome editing detection method for on- and off-target edits, large deletions, and translocations
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poster
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Maresca, Marcello
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Application of In vivo genome and In vivo base editing in drug discovery
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poster
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Marraffini, Luciano
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How the acquisition of new spacers optimizes targeting during the CRISPR-Cas immune response
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talk
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Maumenee, Irene
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CRB1-related retinal dystrophies are ideal recipients for CRISPR-RNP therapy
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poster
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McFaline, Jose L
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Using combinatorial forward genetics and single cell RNA-seq to determine effectors of spatial signaling during the epithelial to mesenchymal transition
|
poster
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McLaughlin, Gemma M
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Gene drives to kill wasps—A novel approach to pest management in New Zealand
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poster
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Miano, Joe M
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CRISPR interrogation of regulatory sequence function in mice
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poster
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|
Min, Yi-Li
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Correction of hot spot mutations in Duchenne muscular dystrophy (DMD) by CRISPR-Cas9 gene editing
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talk
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|
Mittler, Eva-Maria
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Using genome-wide CRISPR/Cas9 screens for identification of host factors required for hantavirus entry and infection in human cells
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poster
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|
Miyaoka, Yuichiro
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Binding affinity of Cas9 to DNA determines its HDR and NHEJ activities
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talk
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|
Morell, Montserrat
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A PCR based method to create long, single-stranded DNA donors for knockin applications
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poster
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|
Muzumdar, Mandar D
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Engineering the cancer genome
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talk
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Nadakuduti, Satya Swathi
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Genome wide evaluation of off-targets caused by targeted gene editing in diploid potato
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poster
|
|
Nakade, Shota
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Selective choice of MMEJ repair pathway and its accuracy profile during the process of PITCh knock-in
|
poster
|
|
Nakamae, Kazuki
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Automated web-based design tool for MMEJ-mediated gene knock-in
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poster
|
|
Neggers, Jasper
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Target identification using large-scale CRISPR/Cas-mediated mutagenesis scanning of essential genes
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poster
|
|
Niakan, Kathy
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Uncovering mechanisms of early human lineage specification by CRISPR/Cas9-mediated genome editing
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talk
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|
Oakes, Benjamin L
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Engineering conditional CRISPR molecules to sense and respond to pathogens
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talk
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Ondrus, Alison E
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Metabolic control of the Hedgehog signaling pathway
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poster
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Petris, Gianluca
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Hit and go Cas9 delivered through a lentiviral based self-limiting circuit
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poster
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|
Pinello, Luca
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CRISPResso2—Ultra-fast quantification of genome editing events for CRISPR-Cas9, Cpf1 and base editors from deep sequencing data
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poster
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|
Porteus, Matthew
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CRISPR/Cas9 based homologous recombination in primary human blood cells—Advancing the technology and moving to the clinic
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talk
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Qin, Peter Z
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CRISPR-Cas9 mediated DNA unwinding detected using site-directed spin labeling
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poster
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|
Riesenberg, Stephan
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Targeting repair pathways with small molecules increases targeted nucleotide substitution efficiency in pluripotent stem cells
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poster
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Robertson, Louise
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Expanding the toolkit for mouse genome editing—Analysis of CRISPR variants with different PAM recognition
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poster
|
|
Ryu, Seuk-Min
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Highly efficient RNA-guided base editing in mouse embryos
|
poster
|
|
Saito, Makoto
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HDAC6-mediated deacetylation of the DDX3X intrinsically disordered region controls stress granule assembly dynamics
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poster
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Saunders, Thom
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CRISPR/Cas9 genome editing pipeline for mice and rats
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poster
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|
Savage, David
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High-throughput approaches for engineering CRISPR-Cas proteins
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talk
|
|
Schneller, Jessica L
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In Vivo genome editing to correct a model of methylmalonic acidemia (MMA)
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poster
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|
Schraivogel, Daniel
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Targeted CRISPR-DropSeq for large-scale functional genomics
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poster
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Sentmanat, Monica
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Validation strategies for CRISPR-Cas9–edited pools
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poster
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Sfeir, Agnel J
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Polymerase theta promotes error-prone repair by alt-NHEJ at the expense of error-free HR
|
talk
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|
Sharma, Sumana
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Genome-wide CRISPR-Cas9 cellular screens to investigate cell surface protein interactions
|
talk
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|
Sheltzer, Jason
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Validating and invalidating cancer drugs and drug targets using CRISPR/Cas9
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talk
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|
Shendure, Jay
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Multiplex strategies for measuring variant effects
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talk
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|
Skor, Maxwell N
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Therapeutic correction of an LCA-causing splice defect in the CEP290 gene by CRISPR/Cas-mediated genome editing
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talk
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Sontheimer, Erik
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Type II-C CRISPR-Cas systems and their natural inhibitors
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talk
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Strezoska, Zaklina
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Identification of genes involved in cell cycle regulation using arrayed synthetic CRISPR RNA libraries in a multiparameter high-content assay
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poster
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Sugano, Shigeo
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Development of versatile modules for NHEJ-based knock-in and optimization of the ratio of donor and cleavage vectors
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poster
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Taghbalout, Aziz
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Casilio-ME—A robust platform for targeted DNA demethylation
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poster
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|
Tak, Esther Yu Gyoung
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Inducible, tunable, and multiplex human gene regulation using CRISPR-Cpf1-based transcriptional activators
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talk
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|
Tan, Meng How
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Comprehensive evaluation of CRISPR-Cas systems for genome editing in human cells
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poster
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|
Tillotson, Eric
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A standard method for benchmarking of CRISPR-associated endonuclease activity as RNPs on free DNA matched substrates and in mammalian cells
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poster
|
|
Tsang, Stephen H
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Mechanistic insights into EFEMP1-related Malattia Leventinese disease and implications for dry AMD
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poster
|
|
Turunen, Mikko
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CRISPR- and CRISPRa screens for identification of target genes for allelic imbalance target regions in colorectal cancer
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poster
|
|
Vakulskas, Christopher
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A novel Cas9 mutant confers reduced off-target gene editing while maintaining on-target potency
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poster
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|
Waigmann, Elisabeth
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EFSA safety assessment of plants obtained through cisgenesis, intragenesis or Site-directed nucleases (SDN-3)
|
poster
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|
Wang, Chia-Lin
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RNAi and CRISPR/Cas9 based in vivo models for drug discovery
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poster
|
|
Wiedenheft, Blake
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A CRISPR immune response to viruses that infect bacteria
|
talk
|
|
Wilson, Ross C
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Tissue-specific delivery of CRISPR-Cas9 via receptor-mediated uptake
|
poster
|
|
Winter, Julia
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Manipulation of MEF-2 activity in the rat brain using CRISPR/Cas9 and its relevance for anxiety, schizophrenia, or autism
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poster
|
|
Wozniakowski, Grzegorz J
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Isolation, molecular analysis and preparation of African swine fever strains for CRISPR/Cas9 modification
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poster
|
|
Yang, Jian-Ping
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GeneArt arrayed lentiviral CRISPR libraries as powerful high-throughput loss-of-function screening tools
|
poster
|
|
Yuan, Celvie L
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Enrichment of CRISPR-mediated homology-directed repair in mammalian cells by cell cycle-based flow sorting
|
poster
|
|
Yudovich, David
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Molecular and bioinformatic workflow for robust NGS-based genome editing quantification
|
poster
|
|
Zhang, Yu
|
CRISPR/Cpf1 correction of muscular dystrophy mutations in human cardiomyocytes and mice
|
poster
|