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Presenting Author
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Abstract Title
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Talk/Poster
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Amendola, M.
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Optimization of dual - gRNA lentiviral vectors for targeted genomic deletions
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poster
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Amrani, N.
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The type II-C Neisseria meningitidis Cas9 is an inherently high-fidelity genome-editing enzyme with novel means of modulation
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poster
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Aparicio, E.
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Scalable tools for knockout of noncoding elements
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poster
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Ardeljan, D.
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CRISPR knockout screen reveals fitness interactions for cells expressing LINE-1
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poster
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Baker, C.A.
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Specification of male versus female acoustic communication behaviors in Drosophila virilis
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poster
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Bandyopadhyay, A.
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CRISPR-CAS9 mediated editing in the EFP genes of rice shows significant alterations in the stomatal number
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talk
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Bansal, M.
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A functional genomics approach to dissect the pathways involved in the mesodermal specification of endothelial and blood progenitor cells and its lineage by using CRISPR/Cas9
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poster
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Bassik, M.C.
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Development of new CRISPR/Cas9-based tools to study drug interactions through knockout and directed evolution
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talk
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Benedetti, L.G.
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Synthetic lethal interaction between the tumour suppressor STAG2 and its paralog STAG1
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poster
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Bier, E.
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The implications of active genetics
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talk
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Bolukbasi, M.F.
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Development of precise chimeric Cas9 platforms for gene therapy applications
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poster
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Botla, S.K.
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Identification of cancer cell type-specific essential transcription factors by pooled CRISPR/Cas9 knockout screening
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poster
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Bourdages, K.G.
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Genome-wide CRISPR screens for Fbw7-specific genetic susceptibilities in cancer
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poster
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Brinkman, E.K.
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Quantitative analysis of Cas9 cutting and repair kinetics in mammalian cells
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talk
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Brunetti, L.
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Fast and efficient CRISPR-Cas9 mediated gene editing in human hematopoietic cells
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poster
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Burgess, S.M.
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Highly efficient knock-ins and knockouts in zebrafish
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poster
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Canela, A.
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DNA breaks and end-resection measured genome wide by end sequencing (END-seq)
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talk
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Chalkley, O.
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Developing predictive methods for designing reduced genomes
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poster
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Challa, A.
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First Year Course-Based Undergraduate Research Experience (CURE) using the CRISPR-Cas9 genome engineering technology in the zebrafish
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poster
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Chang, X.
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Targeted AID-mediated mutagenesis (TAM) in situ identifies functional genetic variants at base resolution
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talk
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Chen, N.
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Optimization of gene editing technology for generation of DEAR1 knockout in human breast cancer cells
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poster
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Cheng, A.W.
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Casilio—An adaptive and multitasking CRISPR-OS for the genome
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poster
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|
Chiasson, M.
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Measuring the effect of every possible VKOR variant in human cells to guide warfarin dosing
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poster
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Christie, K.A.
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CRISPR/Cas9 gene editing in the cornea of a keratin 12- luciferase multitarget knock-in mouse model
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poster
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Conklin, B.
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Genome engineering human iPS cells to model and treat disease
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talk
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|
Corn, J.
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Efficient Cas9 knockin and knockout in challenging contexts
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talk
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Cotta-Ramusino, C.
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Characterization of the interplay between DNA repair and CRISPR/Cas9-induced DNA lesions at an endogenous locus
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talk
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Crawford, E.D.
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DASHing with Cas9—Using targeted nucleases to enhance discovery by deep sequencing
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poster
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DeRisi, J.
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Repurposing CRISPR: Cas9 as a tool to increase efficiency of Next Gen Sequencing
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talk
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DeWitt, M.
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Scarless correction of the sickle mutation in human hematopoietic stem cells using a Cas9 ribonucleoprotein complex
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poster
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Diao, Y.
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CREST-seq, a dual CRISPR/Cas9 mediated tiling deletion based genetic screen method, reveals extensive role of promoters as distal enhancers
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talk
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Dincer, P.R.
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Rare diseases and new therapy modalities – Challenges and opportunities in Turkey
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talk
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Dingal, P.P.
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CRISPR toolkit for mammalian genome engineering and beyond
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talk
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Drummond, R.S.
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CRISPR in outcrossing perennial crops
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poster
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Dziubanska-Kusibab, P.
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Systematic identification of DNA double-strand breaks upon bacterial infection using GUIDE-seq method
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poster
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Eastlund, E.R.
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CRISPR ribonucleoprotein tools for genome editing
|
poster
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Ehsan, H.
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21 century gene-editing technology—CRISPR/Cas9
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poster
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|
Evers, B.
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CRISPR based synthetic lethality screening to identify novel anticancer targets
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poster
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Ewen-Campen, B.
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Tools for Cas9-based transcriptional activation and repression in vivo in Drosophila
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talk
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Ferreira De Mesquita, A.
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Use of Crispr/Cas9 techniques to delineate the crosstalk between autophagy and mTORC1 signaling in breast cancer
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poster
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Findlay, G.M.
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Whole organism lineage tracing by combinatorial and cumulative genome editing
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talk
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Frendewey, D.
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Long-range gene conversion events associated with CRISPR-Cas9-promoted homozygous gene modifications
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poster
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Fuchs, R.
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Characterizing Cas proteins as tools for molecular biology
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poster
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Gallagher, D.N.
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The role of Rad51 and Rad51-associated factors in homologous recombination
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poster
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|
Gao, H.
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Applications of CRISPR-Cas enabled advanced breeding technology in trait development and integration in maize
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talk
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Gasperini, M.J.
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Programmed CRISPR/Cas9 guide pairs for multiplexed deletion scanning of noncoding functional elements across hundreds of kilobases
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talk
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Ge, Y.
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In vivo screen and CRISPR functional genomics identifies novel oncomiRs as drivers in skin cancer
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poster
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Gibb, B.
|
Protein dynamics during presynaptic complex assembly on individual ssDNA molecules
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poster
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Grimont, A.
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Characterization of pancreatic cancer initiation and development in KrasG12R and KrasQ61H mice
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poster
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Guay, D.
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A novel peptide-based agent to deliver Cas9 ribonucleoprotein complex in mammalian cells
|
poster
|
|
Gurumurthy, C.B.
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Efficient generation of knock-in and conditional knockout animal models using Easi-CRISPR
|
poster
|
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Haber, J.
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Learning about recombination initiated by site-specific double-strand breaks from studies in budding yeast
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talk
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Haeussler, M.
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Evaluation of off-target and on-target scoring algorithms and integration into CRISPOR.org
|
poster
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Han, K.
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Massively parallel screening of synergistic drug combinations for cancer via a CRISPR double knockout platform
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poster
|
|
Heidersbach, A.J.
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Combinatorial analysis of validated transcriptional activators reveals an optimized CRISPRa system for inducible or stable gene activation screening
|
poster
|
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Hess, G.
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Directed evolution using dCas9-targeted somatic hypermutation in mammalian cells
|
poster
|
|
Horlbeck, M.A.
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Systematic identification of essential non-coding genes in human cells
|
talk
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Hough, S.
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Designing for success—The right CRISPR design strategies for the right experiment
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talk
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Hough, S.
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DESKGEN Guide Picker—A novel graphical interface for advanced multi-variate design sgRNAs
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poster
|
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Huang, B.
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Using CRISPR to dissect T follicular helper cell development
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talk
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Huang, Y.
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DNA epigenome editing using CRISPR-Cas SunTag-directed DNMT3A
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talk
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|
Huangfu, D.
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A CRISPR view of human development through the lens of embryonic stem cells
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talk
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|
Hur, J.
|
Genome-wide target specificities of CRISPR-Cpf1 nucleases in human cells and mice
|
poster
|
|
Jacobi, A.
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Improved CRISPR editing using chemically-modified crRNA:tracrRNA complexes
|
poster
|
|
Kagawa, H.
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An epithelial program driven by KLF4 stoichiometry determines hallmarks of somatic cell reprogramming
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poster
|
|
Kaur, B.
|
Genetic modifications and functional analyses of Diplonemids
|
talk
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|
Kelder, M.
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High-throughput directed evolution screen of mammalian loci using CRISPR/Cas9 and multiplex homology-directed repair
|
talk
|
|
Kim, S.
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Developing embryonic genome editing using CRISPR/Cas9 and ART
|
poster
|
|
Kleinstiver, B.P.
|
Genome-wide specificities of CRISPR-Cas Cpf1 nucleases
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talk
|
|
Knowlton, M.N.
|
Nomenclature, data integration and disease model identification using mouse genome informatics (MGI)
|
poster
|
|
Koch, B.
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Generation of endogenously-tagged proteins to build a dynamic protein atlas for a systematic understanding of human cell division
|
poster
|
|
Kvon, E.
|
Evolutionary loss of function and in vivo resurrection of a distant-acting limb enhancer in snakes
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talk
|
|
Lee, C.M.
|
Identifying target locus features that influence Cas9 activity
|
poster
|
|
Lemaire, M.
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Genome editing of endothelial cells
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poster
|
|
Li, J.
|
Generation of gene replacements and insertions in rice by intron targeting using CRISPR/Cas9
|
poster
|
|
Li, Q.
|
Genome-wide CRISPR screen identifies lineage determinants and barriers of human definitive endoderm differentiation
|
poster
|
|
Li, W.
|
Genome-wide CRISPR screens identified drivers of endocrine resistance and synthetic lethal vulnerabilities in breast cancer
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talk
|
|
Liang, X.
|
Enhanced CRISPR/Cas9-mediated precise genome editing by improved design and delivery of gRNA, Cas9 nuclease, and donor DNA
|
poster
|
|
Lin, S.
|
A rapid and efficient one-step approach to generate sgRNA template for producing genetically modified mice
|
poster
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|
Listgarten, J.
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Off-target predictive modeling for CRISPR/Cas9 guide design
|
talk
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|
Liu, S.
|
Editing DNA methylation in the mammalian genome
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talk
|
|
Long, C.
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Myoediting—Correction of duchenne muscular dystrophy in humanized mouse models
|
poster
|
|
Lopes, R.
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Functional genetic screens of enhancer elements in human cells using CRISPR-Cas9
|
poster
|
|
Luttgeharm, K.D.
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Development of a high throughput screening protocol for rapid identification of mutated alleles
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poster
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|
Ma, H.
|
CRISPR interrogation of genome dynamics and target recognition in living cells
|
talk
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|
Machado, H.B.
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Experimental design considerations for efficient and specific gene knockin using a CRISPR-Cas9 system with synthetic crRNA and tracrRNA
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poster
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Maizels, N.
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Targeted gene correction by single-stranded DNA donors at DNA nicks and double-strand breaks
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talk
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|
Maji, B.
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Multi-dimensional chemogenic control of CRISPR-Cas9
|
poster
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Mandegar, M.
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CRISPR interference efficiently induces specific and reversible gene silencing in human iPSCs
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poster
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Marraffini, L.
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The role of Cas9 in the generation of immunological memory during the CRISPR-Cas response
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talk
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Mashimo, T.
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Long single-stranded oligodeoxynucleotides (LsODNs) with CRISPR-Cas provide efficient knock-in in zygotes
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poster
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Messer, P.W.
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Evolution of resistance against CRISPR/Cas9 gene drive
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talk
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Morell Fernandez, M.
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Efficient editing of human iPs cells using gesicle-mediated delivery of Cas9-sgRNA protein complex
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poster
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Moreno-Mateos, M.A.
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Optimizing CRISPR-Cas9 to understand zygotic genome activation in vertebrates
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talk
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Morgens, D.W.
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Systematic comparison of genome-wide CRISPR/Cas9 and RNAi screens for the identification of essential genes
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poster
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Morrissey, D.V.
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Robust in vivo gene editing in mouse hepatocytes with systemic lipid nanoparticle delivery of CRISPR/Cas9 components
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talk
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Mosialou, I.
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Crispr/Cas9 genome editing to introduce point mutations in hematopoietic stem cells
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poster
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Moyer, T.C.
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Improved methods for the generation of conditional auxin-inducible degron-tagged genes using CRISPR/Cas9
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poster
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Nakada, S.
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Tandem nicking of one DNA strand enables efficient nucleotide substitution
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poster
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Ouedraogo, J.
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CRISPR/Cas9 genome editing in Aspergillus niger
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talk
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Paix, A.
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Homology-dependent repair in animal cells is local and prone to template switching—Implications for a new approach to genome editing
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talk
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Pan, F.
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Generation of murine isogenic pancreatic cancer organoids with common genetic mutations found in human using CRISPR-Cas9 technology
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poster
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Paquet, D.
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Efficient introduction of homo- and heterozygous mutations using CRISPR/Cas9
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poster
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|
Peters, S.T.
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Using targeted deep sequencing as an improved method for analyzing CRISPR/Cas9 experiments
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poster
|
|
Pinello, L.
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CRISPResso—Streamlined quantification analysis and web application for CRISPR genome editing sequencing experiments
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poster
|
|
Port, F.
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Tissue-specific expression of multiple tRNA-flanked gRNAs for systematic interrogation of gene function in an animal model
|
poster
|
|
Ramlee, M.K.
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Utilizing fluorescent PCR-capillary gel electrophoresis to genotype CRISPR/Cas9-mediated mutants in a high-throughput manner
|
poster
|
|
Regev, A.
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Dissecting regulatory networks with CRISPR screens in immune cells
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talk
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Ross, E.J.
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Characterizing function of chronic kidney disease associated genetic variants of SHROOM3
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poster
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|
Ruiz, S.
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Cas9/RNA-based forward genetic screenings in mouse embryonic stem cells uncovered the role of genes mediating resistance to ATR inhibitors
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talk
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|
Sadhu, M.J.
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CRISPR-directed mitotic recombination enables genetic mapping without crosses
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talk
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Sakuma, T.
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Highly practical gene cassette knock-in in mammalian cells and zygotes mediated by MMEJ
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poster
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|
Schermer, B.
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CRISPR/Cas9 mediated genome-engineering to study glomerular and tubular diseases of the kidney
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poster
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|
Schmidt, S.T.
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Cell lineage tracing using nuclease barcoding
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poster
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Schneller, J.L.
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Targeted genome editing using CRISPR to correct a mouse model of methylmalonic acidemia (MMA)
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poster
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|
Shariati, A.
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Determining feedback mechanisms linking cell cycle control and stem cell pluripotency using an engineered CRISPR/dCas9 system
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talk
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Shi, J.
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Positive-selection screening for rare gain-of-function alleles produced by CRISPR-Cas9 mutagenesis
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talk
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Shin, Y.
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Development of Taq DNA polymerase-specific repebody for hot start PCR
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poster
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|
Singh, S.
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Insights into the Circadian clock temperature compensation mechanism
|
poster
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Skarnes, W.C.
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Rapid, one-step generation of biallelic conditional gene knockouts in cells
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talk
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Smith, J.
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Genome editing for “off-the-shelf” allogeneic CAR T-cell products
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talk
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Smith, J.D.
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High-throughput parsing of complex DNA libraries for isolation and functional characterization of clonal, sequence-verified DNA
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poster
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Smits, B.M.
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CRISPR-Cas9-based targeting of non-coding genetic elements in the 16q12.1 breast cancer risk locus results in gene de-regulation and obesity
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talk
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Somisetty, V.
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Tamoxifen contributes to estrogen-induced gene transcription by inducing a novel subset of enhancer RNAs
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poster
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|
Song, L.
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Recruitment of Pol III promoters in CRISPR/Cas9 system to edit genome of Aspergillus niger
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poster
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Songyang, Z.
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Functional studies of human telomeric proteins using inducible CRISPR KO cells
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poster
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Sontheimer, E.J.
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Phage-encoded Cas9 inhibitors enable genetically-encodable off-switches for genome editing
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talk
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Stegmeier, F.P.
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CRISPR screens provide a comprehensive assessment of cancer vulnerabilities but generate false-positive hits for highly amplified genomic regions
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talk
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Storici, F.
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DNA double-strand break repair by RNA or DNA is more efficient in cis than in trans
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talk
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|
Strezoska, Z.
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High-throughput CRISPR-Cas9 screening with arrayed synthetic crRNA libraries
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poster
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|
Svitashev, S.K.
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DNA-free genome editing in maize using CRISPR-Cas9
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poster
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|
Talas, A.
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A convenient method to pre-screen candidate guide RNAs for CRISPR/Cas9 gene editing by NHEJ-cloning a "self-cleaving" GFP-expression plasmid
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poster
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|
Talwar, T.
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Synergistic unwinding of KH domain and helicase domain in DDX43 helicase
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poster
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Tangprasertchai, N.S.
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CRISPR-Cas9 mediated DNA unwinding detected using site-directed spin labeling
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poster
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Thomas, P.Q.
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Frequent large deletions generated by targeted CRISPR/Cas9 cleavage indicate a novel DNA repair mechanism
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poster
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|
Tsai, S.
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CIRCLE-seq—A highly sensitive in vitro screen for genome-wide CRISPR-Cas9 off-target cleavage
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poster
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Tsang, S.H.
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CRISPR–mediated repair reveals causative mutation in a preclinical model of retinitis pigmentosaa
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talk
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Tuladhar, R.
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Epigenetic mechanisms of genome buffering revealed by CRISPR-Cas9 failures
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poster
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|
van Overbeek, M.E.
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DNA repair profiling reveals nonrandom outcomes at Cas9-mediated breaks
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poster
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|
Vanoli, F.
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Inducible expression of oncogenic fusion proteins upon chromosomal translocation
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talk
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|
Varshney, G.K.
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CRISPR/Cpf1-mediated gene disruption in mouse
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poster
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|
Wainberg, M.
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Off-target behavior of truncated guides in genome-wide CRISPR/Cas9 screens
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poster
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|
Wang, Y.
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CRISPR/Cas based gene targeting in mouse hematopoietic stem cells (HSCs)
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poster
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|
Weege, F.
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Genome-wide CRISPR/Cas9 screens to identify essential host factors for viral infections
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poster
|
|
Wienert, B.
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Introducing a beneficial gain of function mutation suggests a potential gene therapeutic approach for treating β-hemoglobinopathies
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poster
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|
Wojtal, D.
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Treatment of multi-exon duplications In Duchenne muscular dystrophy
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poster
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|
Wolter, F.
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Highly efficient heritable plant genome engineering using Cas9 orthologues from Streptococcus thermophilus and Staphylococcus aureus
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poster
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|
Woltjen, K.
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Simultaneous derivation of disease-relevant point-mutants and concordant isogenic clones from human induced pluripotent stem cells
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poster
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|
Worley, J.
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Identifying the regulators of transcriptional programming in tumor subpopulations using multiplexed single-cell RNA-seq, single-cell VIPER, and CRISPR/Cas technology
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poster
|
|
Wright, A.
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Protecting genome integrity during CRISPR immunity adaptation
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talk
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|
Wu, L.
|
CRISPR/Cas9 gene editing in mouse zygotes
|
poster
|
|
Wu, Q.
|
In situ functional dissection of a native miRNA target-network by multiplex genome engineering
|
poster
|
|
Wu, X.
|
Using CRISPR-Cas9 genome editing to reveal new gene functions by protein subcellular redistribution
|
poster
|
|
Xu, W.
|
Optimization of CRISPR-dependent deletion of the gene encoding the novel cAMP sensor NCS-Rapgef2 in a Cas9-expressing rat neuroendocrine cell line
|
poster
|
|
Xue, W.
|
in vivo CRISPR-Cas9 genetic screen for liver cancer
|
talk
|
|
Younis, S.M.
|
Efficient genome editing in murine myoblasts using CRISPR/Cas9 system reveals the role of ZBED6 in myoblast growth and differentiation
|
poster
|
|
Zhang, Y.
|
Efficient and transgene-free genome editing in wheat through transient expression of CRISPR/Cas9 DNA or RNA
|
poster
|