Molecular Mechanisms of Neuronal Connectivity
September 8 - 11, 2020

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**Please check your email for the length of your talk, poster instructions, links to the webinar, and how to prepare and submit your poster PDF for the virtual poster session. 

Abstract Status

Presenting Author

Abstract Title

Talk/Poster

Abolafia, Jane

Connecting developmental transcriptomic signatures of spinal commissural neurons to circuit function

poster

Ackerman, Sarah D

Astrocytes close a critical period of motor circuit plasticity

poster

Adams, Eliza L

Large-scale activity-dependent axonal structural plasticity in adult brain―Logic and mechanisms

talk

Agrawal, Manasi

Dscam overexpression impairs neuronal morphology during development

poster

Ahmed, Maria

Generation of sparse, combinatorial wiring for sensory coding

poster

Aihara, Shuhei

Selective dendrite stabilization is controlled by BMPR2 in developing mitral cells

talk

Aimino, Michael

Distinct classes of olfactory neurons develop synapses under unique temporal and molecular conditions

poster

Alexander, Kellianne D

Transcriptional control of synapse elimination during C. elegans  neural circuit remodeling by the homeodomain transcription factor DVE-1

talk

Allen, Nicola J

Activity dependent control of synapse regulating genes in astrocytes

talk

Aviles, Evelyn

Fat3 controls synapse localization through its intracellular domain

poster

Baccini, Victoria L

Examining the nanoscale organization of inhibitory spine synapses

poster

Bajar, Bryce T

Genetic disruption of developmental activity alters synapse formation

poster

Bali, Namrata

Interactions between the Drosophila Lar receptor tyrosine phosphatase and a novel cell surface ligand regulate neuromuscular junction morphogenesis, mushroom body architecture and R7 photoreceptor axon targeting

poster

Ban, Yue

Prickle2 promotes glutamatergic synapse formation and maintenance.

poster

Bañón González, Aitor

Identification of inner ear pioneer axons and characterization of their role in the organization of the statoacoustic ganglion

poster

Bhattacharya, Martha

TMEM184B promotes pruriceptive neuron specification to allow itch sensitivity

talk

Biederer, Thomas

Concerted functions of synapse organizers impact prefrontal cortex connectivity and cognitive functions

talk

Blockus, Heike

Synaptogenic activity of the axon guidance molecule Robo2 shapes spatial representations in hippocampal CA1

talk

Bludau, Anna

Lateral septum miRNA alterations in response to social fear conditioning―Functional involvement of miR-132 in extinction and oxytocin-mediated reversal of social fear

poster

Boato, Francesco

OPHN1 controls the dynamics of radially-migrating neurons in the developing cerebral cortex

poster

Brookes, Emily

Regulation of the Bdnf gene by genome topology and a novel enhancer during neuronal development

poster

Brovkina, Margarita

The gene regulatory architecture of sexually dimorphic neural circuits in Drosophila melanogaster

poster

Buck, Matthias

Plexin-Bs enhance their GAP activity with a novel activation switch loop generating a cooperative enzyme for axon guidance

poster

Buelow, Pernille

Activity dependent regulation of protein synthesis via RNA granules is absent in Fmr1 KO neurons during homeostatic plasticity

poster

Burk, Katja

Rab7- endosomes act as sorting platforms for neurotrophic receptors to enable signaling

poster

Cai, Ruiyao

Whole body neuronal circuitry in health and disease revealed by vDISCO nanobody labeling, clearing and light-sheet imaging

poster

Castellani, Valérie

Commissural axon navigation of the floor plate requires SlitC-PlexinA1-mediated iterative inhibition of growth cone exploration

talk

Chakraborty, Sumita

Critical role of bioenergetics in neuronal remodelling

talk

Chang, Chao

Phr1, an intracellular signalling hub with ubiquitin ligase and guanine exchange factor activities, functions in ephb2 signalling

poster

Chang, Leechung

The involvement of glial cell-derived factors in remodeling of the cortico-mesencephalic projection after unilateral cortical ablation

talk

Chaudhari, Karina

Robo recruitment of the wave regulatory complex plays an essential and conserved role in midline repulsion

talk

Choi, Seungwon (Sebastian)

Parallel ascending spinal pathways for affective touch and pain

poster

Choudhury, Saumitra D

High resolution in vivo detection and reconstitution of synaptic proteins using a novel nanobody-based system

poster

Cizeron, Melissa

Role of MADD-4/Ce-Punctin processing at the neuromuscular junction

poster

Co, Marissa

Altered cortical development in mice harboring autism-associated Tbr1 mutations

poster

Coakley, Sean

Epidermal control of axonal attachment via β-spectrin and the GTPase-activating protein TBC-10 prevents axonal degeneration

poster

Corradi, Eloina

precursor miRNAs―Novel mechanisms of transport and function in developing axons

talk

Cuentas-Condori, Andrea A

Activity-dependent bulk endocytosis is hijacked to dismantle presynaptic terminals in remodeling neurons.

poster

Darwin Arulseeli, Divya

Remotely produced and axon-derived Netrin-1 instructs GABAergic neuron migration and dopaminergic substantia nigra development in the ventral midbrain

poster

Deans, Michael R

Planar cell polarity signaling directs growth cone guidance through a non-autonomous mechanism acting in target tissues

poster

DeLoughery, Zachary

Investigating Robo3's role in specifying contra- versus ipsilateral axon projections in the spinal cord.

poster

Dey, Swagata

Dendrite regeneration is independent of DLK/MLK pathways of axon regeneration in PVD neurons of Caenorhabditis elegans

poster

Dima, Raphael

The number of neurites and polarized cell extensions is regulated by heparan sulfate proteoglycans

poster

Dona, Erika

Genetic origin and behavioural significance of a sex specific circuit switch in Drosophila

poster

Duan, Qichen

Deciphering the cell surface codes underlying the assembly of Drosophila olfactory circuits

poster

Dube, Shataakshi

Action potential-coupled Rho GTPase signaling drives presynaptic plasticity

poster

Düdükcü, Özge

Role of axon guidance molecules in GABAergic neuron positioning in the developing ventral midbrain

poster

Eichel, Kelsie

Endocytosis of dendritic proteins in the axon initial segment safeguards neuronal polarity

poster

Emmons, Scott

The landscape of cell adhesion proteins across a neural network of known structure suggests a code for neural wiring

poster

Escalante, Augusto

Spinal inhibitory Ptf1a-derived neurons prevent self-generated itch

poster

Espindola de Freitas, Andiara

Single cell transcriptomic analyses in a model of chronic stress

poster

Estep, Jason A

Cas adaptor proteins mediate external capsule fasciculation

poster

Falk, Julien

Galvanotropism enables navigating axons to locate their target at a distance

poster

Favuzzi, Emilia

A dedicated microglia population selectively sculpts developing inhibitory circuits

talk

Feng, Bo

Aβ oligomers induce loss of glutamatergic synapses by targeting the planar cell polarity signaling pathway

talk

Feresten, Abigail H

What guides the leaders―Identifying factors involved in pioneer axon extension

poster

Formicola, Nadia

The neuromodulator Tyramine induces the remodeling of neuronal RNP granules in Drosophila brains

poster

Fournier, Alyson E

Targeting protein-protein interactions to promote axon regeneration

talk

Fujimoto, Satoshi

Activity-dependent competition within a neuron ensures the discrete wiring of mitral cell dendrites

poster

Gaspar, Patricia

Implication of 5-HT7 receptor in prefrontal circuit assembly and detrimental emotional effects of SSRIs during development

poster

Giniger, Edward

Computational simulations suggest that the spatial distribution of actomyosin in the growth cone is controlled by the ratio of linear to branched actin

poster

Gogou, Christos

Constructing a cryo-EM assay for molecular voltage-sensitivity of liposome-reconstituted membrane proteins

poster

Goldblatt, Dena

Tangential nucleus subtypes in the larval zebrafish are specified and organized independently of motoneuron-derived signals

poster

Goldner, Ron

Modular and distinct PlexinA4/FARP2/Rac1 signaling controls dendrite morphogenesis

talk

Gonzalez, Constanza

A possible Slit recycling pathway acting during the development of the Drosophila visual system

poster

Goodrich, Lisa

A sound basis for hearing―Runx1 controls neuronal diversity and circuit function in the cochlea

talk

Gorla, Madhavi

A conserved E3 Ubiquitin ligase pathway targets Robo receptors for degradation to allow commissural axons to cross the midline

poster

Grill, Brock J

Genetic behavioral screen identifies an orphan anti-opioid system

talk

Grooms, Noa

PVQ synaptic input to ASJ modulates neurite outgrowth

poster

Guy, Adam T

Radial glial sPLA2 V enzyme modulates LysoPtdGlc/GPR55-mediated axon guidance of nociceptive sensory afferents

poster

Haimson, Baruch

A subpopulation of spinocerebellar tract neurons regulates the stability of bipedal stepping

poster

Harvey, Beth M

The glycosyltransferase Lh3 encodes a novel regulator of optic nerve regeneration.

talk

Hauser, David

Regulation of synaptic adhesion molecules by RNA processing

talk

Heckman, Emily L

Adhesion mechanisms that enable synapse maintenance and restoration

talk

Hernandez, Luiselys M

JAK1 palmitoylation by ZDHHC3/7 is essential for neuropoietic cytokine signaling and DRG neuron survival

poster

Ho, Xue Yan

The metalloprotease ADAM17/ADM-4 promotes regenerative axonal fusion by stabilising the fusogen EFF-1

talk

Hruska, Martin

Robust rules of modularity govern the nano-organization of excitatory spine synapses

poster

Hu, Yujia

A neural basis for categorizing sensory stimuli to enhance detection accuracy

poster

Hunyara, John L

Transcriptomic signatures of ipRGC subpopulations during early postnatal development

poster

Isabella, Adam J

Temporally patterned chemoattractant signaling guides vagus topographic map development

talk

Jahncke, Jennifer

Purkinje cell Dystroglycan promotes the function of inhibitory basket synapses in cerebellar cortex.

poster

Jeong, Heykyeong

Coupled control of distal axon integrity and somal responses to axonal damage by the palmitoyl acyltransferase ZDHHC17

poster

Ji, Hui

Phagocytosis drives NAD+ reduction-induced dendrite degeneration in Drosophila

poster

Kalinski, Ashley L

SARM1 mediated degeneration of peripheral nerve fibers regulates Schwann cell reprograming, axon regeneration, and functional recovery

talk

Kaneko, Takuya

Topographic separation of sensory-motor reflex circuits in the zebrafish vagus system

poster

Kania, Artur

Phox2a defines a developmental origin of the anterolateral system in mice and humans

talk

Kellermeyer, Riley

Tolloid related proteases process Slit to generate novel activities

poster

Kerstein, Patrick C

Gbx2 identifies and regulates the development of an atypical interneuron in the mouse retina.

talk

Kindt, Katie

Role of hair cell neurotransmission in sensory synapse and circuit function

talk

Klar, Avihu

Evolution of neuronal and genetic mechanisms that control flying in vertebrates

talk

Kobe, Bostjan

Structural basis of function of SARM1 in axon degeneration

talk

Kokan, Nikolas

LRON-11 functions in axon guidance within the ventral nerve cord of C. elegans

poster

Landinez, Maria

Subcellular control of synaptogenesis by the RNA-binding protein Musashi specifies synapse number and pattern for individual axon branches

poster

Lee, Kristen

Characterizing the role of developmental transcription factors in neural circuit establishment and maintenance in Drosophila

poster

Li, Tongchao

Live imaging of neural circuit assembly in the Drosophila olfactory system

poster

Liang, Xing

Growth cone-localized microtubule organizing center establishes microtubule orientation in dendrites

poster

Lin, Ying

A cascade of transcription factors provides temporal control of gene expression during neural circuits formation

poster

Liston, Conor

Sustained rescue of prefrontal circuit dysfunction by antidepressant-induced spine formation

talk

Liu, Hao

Dscam gene triplication causes neocortical overinhibition in Down syndrome

talk

Liu, Yingtao

A disinhibitory neural circuit for bending posterior segments in the initial phase of forward locomotion in Drosophila larvae

poster

Longley, Colleen M

Neuroligin 2 is critical for proper formation of inhibitory synapses onto GABAergic interneurons

poster

Lu, Yangning

How an asymmetric neuronal circuit generate symmetric behavior

poster

Machado, Natalia L

EP3R-expressing glutamatergic neurons mediate inflammatory fever

poster

Maness, Patricia

Semaphorin signaling drives selective spine pruning through actin cytoskeletal regulation

poster

Mao, Yuting

EphB-ephrinB cis interaction in filopodial movement

poster

Mastick, Grant

Slit signals control oculomotor nerve fasciculation, navigation, branching, and connectivity

poster

Matho, Katherine S

Genetic dissection of glutamatergic neuron subpopulations and developmental trajectories

poster

McDonald, Nathan A

Synaptic active zone assembly requires scaffold molecule phase separation

talk

Meijer, Dimphna

Structural insights into covalent dimerization of synaptic cell adhesion molecules

talk

Meijers, Rob

Netrin synergizing activity factors affect conditional adhesion between neurons

talk

Menon, Kaushiki

DIP-γ and Dpr11 interactions control selection and survival of amacrine neurons in Drosophila color vision circuits

poster

Menon, Rohit

Septal HDAC1 regulates long lasting social fear extinction in male mice

poster

Meserve, Joy H

Neuroepigenetic regulation of a tunable behavioral circuit

poster

Moore, Adrian

Atypical myosin tunes dendrite arbor subdivision

poster

Moret, Frederic

Norbin is required for the transition between direct to indirect neurogenesis in the developing mouse cortex

poster

Murphy, Patti

Robo2 and specialized glia promote target-specific axon regeneration by regulating pathway choice at a nerve branch-point

poster

Nadour, Malika

The extracellular matrix protein MIG-6/papilin mediates the maintenance of neuronal architecture

talk

Navarro, Maria F

Deciphering the cellular and molecular mechanisms by which celsr3 promotes CNS regeneration

poster

Nelson, Jessica C

Hip14 regulates habituation learning and acoustic startle thresholds through distinct circuit modules

poster

Nguyen, Huu T

Different BMP signaling modalities sculpt synapse development and plasticity at the Drosophila neuromuscular junction

poster

Nguyen, Phi

Microglial control of synaptic plasticity via extracellular matrix remodeling

talk

Niu, Jingwen

Multiple palmitoyl-proteins in the DLK signaling pathway are critical for neuronal degeneration

poster

Okur, Zeynep

Bone morphogenic protein signaling exhibits distinct role on regulation of cortical plasticity

poster

Opatowsky, Yarden

SARM1 ring to rule them all

talk

Ozkan, Engin

The roles of networks of extracellular interactions in driving neuronal connectivity

talk

Pak, Joseph

Structure of the Robo3-NELL2 complex reveals mechanisms of signaling in spinal cord axon repulsion

poster

Palumbos, Sierra

cAMP controls a trafficking mechanism that directs the neuron specificity and subcellular placement of electrical synapses

talk

Pan, Simon

Preservation of a remote fear memory requires new myelin formation

poster

Pasca, Sergiu P

Establishing and probing human neuronal connectivity with stem cell brain derived assembloids

poster

Pascual Vargas, Patricia

A post translational modification regulates the trafficking and synaptogenic activity of the Wnt receptor Fz5

poster

Pederick, Daniel

Latrophilin-2 repels Teneurin-3+ hippocampal axons during target selection

talk

Perry-Hauser, Nicole A

G12/13 is activated by acute tethered agonist exposure in ADGRL3, an adhesion GPCR associated with ADHD and substance use susceptibility

poster

Philippidou, Polyxeni

Phrenic-specific transcriptional programs shape respiratory motor output

poster

Pizzano, Sarah A

Interactions of Down syndrome-related genes in neurodevelopment

poster

Pollitt, Stephanie

LIM and SH3 Protein 1 localizes to the leading edge of protruding lamellipodia and regulates axon development

poster

Pomaville, Matthew

Follicle innervating neurons form receptive fields through competition mediated interactions

poster

Ramsey, Austin M

LRRTM2 maintains synaptic strength through the subsynaptic positioning of AMPARs

talk

Rastegar, Shima

Dcc loss from Phox2a neurons dissociates pain localisation from its affective dimension

poster

Rico, Beatriz

Molecular programs orchestrating the wiring of different inhibitory circuits

talk

Romano, Valentino

A Boolean model of the protein network regulating growth cone collapse in vertebrate neurons

poster

Rosenthal, Justin S

Developmental switching of nicotinic acetylcholine receptor subunits supports central cholinergic synapse maturation

poster

Royer, Melanie

Identification of a long non-coding RNA involved in social fear extinction

poster

Rumpf, Sebastian

Tissue mechanics underlie dendrite severing during neurite pruning in the Drosophila PNS

poster

Saied Santiago, Kristian S

Drug screen to uncover genes and molecular pathways required in optic nerve regeneration in larval zebrafish

poster

Sakai, Naoko

Elucidating the functions of cell adhesion molecules in determining neuronal connectivity in C. elegans

poster

Santana, Yessica C

Isl1 is required for the specification and the morphological maintenance of starburst amacrine cells

poster

Santiago, Sarah E

Global proteomic analysis reveals that disruption of endolysomal/autophagic trafficking affects multiple aspects of brain development including neuronal adhesion and axon pathfinding molecules

poster

Sathyamurthy, Anupama

Brain proposes, spinal cord disposes―Organization and function of cerebellospinal neurons

poster

Schmucker, Dietmar

Molecular mechanisms of neurite branching and central synapse formation

talk

Seiradake, Elena

A combinatorial code in brain development―What do we know about Lphn, FLRT, Unc5 and Teneurin in cortical development?

talk

Sengupta, Mohini

Decoding the role of asymmetric ipsilateral inhibition in axial motor circuits

poster

Seroka, Austin P

Single-cell transcriptomic analysis of distinct neuroblast lineages in the developing Drosophila embryo

poster

Serradj, Nadjat

Ephrin signaling limits recovery after corticospinal tract injury

talk

Shohayeb, Belal M

The microcephaly gene wd40-repeat protein 62 (wdr62) regulates neural stem cells differentiation and cilia formation in mouse neocortex

talk

Shrestha, Pravesh

Structural and functional studies of the effects of phosphorylation on ephrin receptor tyrosine kinase, EphA2, and the relationship with its SAM domain as an autoinhibitor

poster

Shuster, Andrew

GluD2- and Cbln1-mediated competitive synaptogenesis shapes the dendritic arbors of cerebellar Purkinje cells

poster

Sitko, Austen A

Anatomical and molecular development of olivocochlear efferent neurons

poster

Slavi, Nefeli

Ipsi- and contralateral retinal ganglion cell identity in the pigmented and albino retina

poster

Soba, Peter

Modality- and circuit-specific neuromodulation computes discrete escape behavior

poster

Soderling, Scott

Chemico-genetic discovery of astrocytic control of inhibition in vivo

talk

Song, Yuanquan

Glial metabolic reprograming promotes axon regeneration and functional recovery in the central nervous system

talk

Spoelstra, Willem Kasper

A game theoretical representation of neuronal network formation

poster

Stern, Jamie

UNC-115/abLIM, a conserved regulator of actin dynamics, drives dendritic branching in the PVD neuron.

poster

Sullivan, Kelly G

Trafficking and degradation of axon guidance receptors at the Drosophila embryonic midline

poster

Tan, Liming

Vision reconstructs the cellular composition of binocular circuitry during the critical period

talk

Taylor, Russell

Role of F-BAR proteins in process extension and neuronal migration in the embryonic cortex

poster

Taylor, Seth

A single-cell gene expression atlas of an entire nervous system

talk

Tombesi, Giulia

The Parkinson’s disease kinase LRRK2 promotes dendritic spine formation via BDNF signaling pathway

poster

Trotter, Justin

Neuronal and astrocytic neurexin-1 differentially sculpt synaptic function

poster

Tsai, Nicole

Mapping parallel retinal outputomes onto superior colliculus with trans-seq

talk

Tulloch, Alastair J

NELL2 and Robo3 control axon guidance and neuronal migration in the developing spinal cord

poster

Ulloa Severino, Francesco Paolo

Role of cortical synaptogenesis in the adaptability of goal-directed actions

poster

Vaddadi, Neelima

Structural basis and function of Kirrel3 homophilic adhesion in axonal targeting

talk

Vahedi-Hunter, Tyler

ExBoX―A simple Boolean exclusion strategy to drive expression in neurons

poster

Vakonakis, John

The RIM C2A domain couples Ca2+ channels and release sensors at presynaptic active zones

poster

van de Haar, Lieke

Single-cell RNAseq reveals cellular subset-specific gene expression in the developing mouse habenula

poster

Varadarajan, Supraja G

Probing the role of retinorecipient target cells in regeneration

poster

Verhagen, Marieke G

Layer-specific cortical development depends on Semaphorin6A reverse signaling

talk

Vicenzi, Silvia

Serotonin functions as a bidirectional guidance molecule regulating growth cone motility

poster

Vicidomini, Rosario

Neto controls synapse organization and Presynaptic Homeostatic Potentiation at the Drosophila NMJ

talk

Vijayaraghavan, Tarika

The dynamin GTPase is required for regenerative axonal fusion

poster

Walker, Lauren

Identification of extrinsic cues promoting target-selective axon regeneration

poster

Waller, TJ

Linking synaptic structure and degeneration at the Drosophila NMJ via the transmembrane protein Raw

poster

Wang, Minghui

Oligophrenin-1 moderates behavioral responses to stress via regulation of parvalbumin interneuron activity in medial prefrontal cortex

poster

Wang, Yuchen

Leucine-rich repeat proteins mediated trans-synaptic modulation of functional wiring of cone photoreceptors

poster

Wani, Adil

The cellular and molecular program regulating the fate specification and identity of sleep-promoting neurons in Drosophila melanogaster

poster

Ward, Patricia J

Activity-based therapy and role of HIF1α in axon regeneration

poster

Washburn, Halley R

Extracellular charge-dependent EphB-NMDAR interaction regulates NMDAR mobility at dendritic spines.

poster

Weghorst, Forrest

Caspase-3 cleaves extracellular vesicle proteins during auditory brainstem development

poster

Williams, Megan

Target-specific synapse formation by the cell adhesion molecule Kirrel3

poster

Williams, Michael

AnteroTag, a protein engineering strategy for transsynaptic anterograde access

poster

Winter, Julia

Chronic oxytocin-driven alternative splicing of CRFR2α induces anxiety

talk

Wirak, Greg S

Age related decline of neuronal connectivity and function in C. elegans

poster

Wisdom, Elias M

Investigating the role of gap-junctions in the performance of a learned behavior

poster

Wong, Wenny

Cas adaptor proteins regulate cortical migration and lamination

poster

Xu, Shuwa

Significance of affinity variation of cell surface recognition molecules in wiring the nervous system

talk

Yamamoto, Nobuhiko

Patterned stimulation regulates Bdnf promoter activity spatiotemporally in upper layer cortical neurons

poster

Yokoyama, Kazunari

Cystine-glutamate antiporter xCT/Slc7a11 controls ROS-mediated apoptosis through JDP2-Nrf2- p21Cip1 complex in mouse cerebellar granule cells

poster

Yonan, Jennifer M

De novo growth of adult dentate granule neurons triggered by PTEN deletion does not lead to disruption of connectional specificity

poster

Yu, Fengwei

Establishing Drosophila as a model to study the roles of medicinal cannabinoids in pain relief, ageing and neurodegeneration

poster

Zang, Yixin

Crossing the midline requires sequential proteolysis of the frazzled axon guidance receptor

poster

Zhang, Qiuxiang

In vivo investigation of synaptic transmission in zebrafish lateral line system

poster

Zhang, Zhe

A role for postsynaptic Fmr1 and whisker sensory experience in development of callosal synaptic connections

poster

ZHOU, Xin

The heparan sulfate proteoglycan syndecan/SDN-1 bridges ECM and intracellular scaffolds to localize the α7-like nicotinic receptor ACR-16 at synapses

poster