Assembloids
December 8 - 11, 2025

You must register for the meeting in order to submit abstracts.
After registering you will be sent a web link for abstract submission by email.
You may copy and paste your abstract from Word, Google Docs, or Notepad; abstracts are limited to ~2900 characters.

Program information: An electronic version of the program abstract book will be sent three working days prior to the first day of the meeting, and hard copies will be available for collection upon your arrival at Cold Spring Harbor Laboratory. First night and keynote speakers are informed of their session date and time, otherwise program information is only available upon release of the electronic version of the abstract book. The reason we do this is to try and maximize interactions by encouraging participants to stay for the duration of the meeting.

Please check your email for talk length, poster instructions, and how to have your poster printed at CSHL for collection upon arrival. 

Abstract Status

Presenting Author

Abstract Title

Talk/Poster

Ahmad, Vakil

Development of an endometrial assembloid model to study endometriosis-associated pain

poster

Alvarez, Natalie

Adapting the BEHAV3D platform to a 24-camera multiarray microscope to enable scalable interrogation of T cell behavior in immuno-oncology cocultures

poster

Ariese, Hendrikus Cornelis Rijndert

Generating a brainstem-regionalized organoid model for accurate diffuse midline glioma modelling

talk

Astro, Veronica

Supernumerary X chromosomes shape brain organoid architecture and functions in a dose-dependent fashion

poster

Atencia Taboada, Lidia

Cell–cell interactions dictate the success of GSK-3/BCL-XL combination therapy in colorectal cancer

poster

Avabhrath, Nagashree K

Craniofacial chondrogenesis from human neural crest stem cells to model disease pathogenesis in arrhinia

poster

Brahmendra Barathi, Bhargavi

Characterizing the functional impact of germline-inherited risk alleles in glioma evolution

talk

Brand, Andrea H

Quiescent neural stem cells transiently become neuronal to coordinate long-range reactivation

poster

Bunn, Claire E

An in vitro model of homeostasis explores basal cell lineages in the human airway epithelium

poster

Chaggar, Harman Kaur

α-synuclein-induced senescence as a driver and therapeutic target of Parkinson’s disease

poster

Chakravarti, Shukti

Therapeutic wound healing using corneal organoid derived stromal cells

poster

Chen, Serena

Acetyl-CoA synthetase 2 regulates acetate-induced transcriptional programs in astrocytes

poster

Chew, Leon H

In vitro airway epithelial and neural assembloid platforms to model in vivo human organ-specific immune responses

poster

Crooks, Gay M

3D artificial thymic organoids for the generation of mature human T cells from stem cells

talk

da Silva Camargo, Claudia

Transcriptomic insights in Williams syndrome—An iPSC-derived neural cells model approach

poster

Devalla, Harsha D

Decoding rhythm regulation using human cardiac assembloids

talk

Domene, Adrian

Modeling HIV associated neuropathology in a novel microglia containing brain organoids

poster

Fan, Yujie

Human gut–vagus–brain assembloids for dissecting α-synuclein aggregates propagation in Parkinson’s disease

talk

Fitzgerald, Michael Q

High throughput quality control for shaker-based culture of cortical organoids

poster

Fokkert, Lianne

Engineering neuro-cardiac assembloids to model rhythm regulation

poster

Hamann, Catherine A

An assembloid model of frontotemporal dementia with MAPT mutations

poster

Hamazaki, Nobuhiko

Self-organization in post-gastrulation human development—Assembly of anterior and posterior embryo models

poster

Hetzer, Martin

Protein longevity as a regulatory principle of lifelong neuronal function and aging

talk

Heydari, Zahra

The impact of micro- and nanoplastics on telomere length in organoids derived from normal colon and polyps of patients with early- or average-onset colorectal cancer

poster

Hoeffler, Warren K

Disease modeling using assembloids, recapitulating normal physiology enables modeling disease physiology

poster

Huang, Kang-Chieh

Modeling amyloid plaque formation and glia-neuron interactions in human iPSC-derived mono and tri-culture systems

poster

Kang, Kyung-Sun

Glioblastoma–blood vessel assembloids as a humanized model of the tumor microenvironment

poster

Kim, Eunjee

A stepwise, modular design of building uniform cortical assembloids representing the dynamic cellular interplay between neurons and glial cells

poster

Kim, Eunjee

Identification of neuron-glia signaling feedback in human schizophrenia using patient-derived, mix-and-match forebrain assembloids

poster

Kim, Hwisoo

A hanging drop microarray platform for high-throughput manipulation of brain organoid arrays

poster

Kim, Minji

Human skin assembloids model allergen-induced inflammation with immune–vascular crosstalk

poster

Kim, Suel Kee

Human-specific regulation of pontocerebellar connectivity by zona pellucida glycoprotein 2

poster

Kim, Yena

Modeling of Parkinson’s disease using iPSC with LRRK2 gene mutation

poster

Kiral, Ferdi Ridvan

In vitro reconstruction of human pineal gland for melatonin production and disease modeling

poster

Koehler, Karl

Modeling regionalized skin in ectoderm-mesoderm assembloids

talk

Kumar, Manoj

Dissecting the genetic basis of thalamo-cortical activity using human assembloids

poster

Le, Anh Phuong

Building amnioids and ventral skin organoids from assembling ectoderm-mesoderm progenitors

poster

Liberali, Prisca

Scaling life—How single cells orchestrate tissue-level coordination

talk

Lim, Hyeonji

Developmental hypoxia drives the maturation and architectural complexity of kidney organoids

talk

Liu, Wei

Self-formation of concentric zones of telencephalic and ocular tissues and directional retinal ganglion cell axons

poster

Liu, Zukai

Dual-patterned pluripotent stem cells self-organize into a human embryo model with extended anterior-posterior patterning

talk

Lucas, Emma

Endometrial assembloids to model implantation and reproductive dysfunction

talk

McGeary, Sean E

Systematic dissection of adhesion codes with live-cell optical barcoding

poster

Medina, Pedro

Spatially patterned kidney assembloids recapitulate progenitor self-assembly and enable high-fidelity in vivo disease modeling

talk

Micali, Nicola

Early developmental origins of cortical disorders modeled in human neural stem cells

poster

Ming, Guo-li

Modeling glioblastoma cell-neuron interaction using assembloids

talk

Mirsadeghi, Sara

Uncovering mechanisms of hyperexcitability in ARX mutant brain organoids during neurodevelopment

poster

Mocle, Andrew

Generating multi-lineage peripheral somatosensory organoids to model sensory dysfunction

poster

Monz, Elisa

Integrating high-density functional recordings with high-resolution imaging to study neuromuscular organoids—From electrical signatures to electron microscopy

poster

Mukherjee, Shreyasi

Chromatin remodeling by Polycomb repressive complexes regulates the spatiotemporal emergence of mammalian body plan in mouse gastruloids

talk

Nguyen, Claudia V

Thalamic NRXN1-mediated input to human cortical progenitors drives upper layer neurogenesis

poster

Park, Hyeyeon

Modeling Alzheimer’s disease in human cortical-blood vessel assembloids

poster

Passaro, Austin

Functional analysis of iPSC-derived three dimensional models on traditional and novel microelectrode arrays

poster

Perez, Oscar

A single plasmid system for multiplexed CRISPR gene tagging in induced pluripotent stem cells

poster

Poynter, Cassidy L

Leveraging organoid models to assess microplastic neurotoxicity

poster

Predes, Danilo

ZNF711 cooperates with the Wnt/β-catenin signaling pathway to regulate differentiation and growth of intestinal stem cells and colorectal cancer

poster

Rawlins, Emma

Organoid modelling of human lung alveolar epithelial differentiation to determine developmental mechanisms and develop disease models

talk

Ritchie, Arabela

Establishing human liver assembloids by integrating hepatocyte organoids with non-parenchymal cells and defined hydrogels

poster

Rivron, Nicolas

Molecular determinants and evolution of timing of human implantation

talk

Rocha, Vivian G

Microcephaly-like phenotype triggered by novel reassortant and prototypic Oropouche Virus strains in brain organoids

poster

Rodriguez de la Rosa, Alejandra

Recapitulating neuromuscular and muscle-tendon interfaces from human pluripotent stem cells

talk

Setya, Michael G

Investigating the role of nerve growth factor in neuro-cardio-vascular co-development in a human 3D innervated cardiac muscle model

poster

Shin, Kunyoo

Patient-derived RCC assembloids identify tumoral Wnt-unresponsive CAFs disrupting tumor–CAF–T cell crosstalk to promote immunotherapy resistance

talk

Shoshkes-Carmel, Michal

Transcriptome profiles of telocytes along the intestinal crypt-villus axis

poster

Silva Oliveira, Luiz Fernando F

Multilineage intestinal organoids identify a critical mechanistic process in WNT2B loss-of-function

talk

Skefos, Jerry E

High resolution neural activity mapping in human-iPSC derived guided cortical organoids via high-density multi-electrode array technology

poster

So, Kyoung-ha

Development of decellularized urinary bladder matrix based cryogel for promoting angiogenesis

poster

Stejskalova, Anna

Organ-on-chip model of primary human fallopian tube for reproductive health studies

poster

Stout, Randy F

Intercellular gene regulation and mitochondrial transfer through gap junctions in assembled cell models of brain tissue

poster

Sun, Dawei

Slidetags reveals the spatiotemporal coordination of immunity and repair in the influenza-infected lung

poster

Sun, Na

Uncover the functional contributions of cell-cell communication in disease genetics

poster

Szalai, Timea

In vitro modeling of multiorgan involvement in 22q11.2DS

poster

Tang, Jocelyn

From development to disease—Investigating the role of the neural stemness factor Tailless (TLX) in the disease progression of glioblastoma

talk

Tang, Xin

Investigating microglia/tumor interactions and oncological therapy responses in neuroimmune-competent human brain organoids

poster

Thonon, Lisa

Patient-derived isogenic retinal organoids modelling photoreceptor degeneration in rhodopsin-associated retinitis pigmentosa

poster

Tracey, Angelica

Investigating the role of interferon signaling in the malformation of the Down syndrome lung

poster

Tran, Khanh

Cadmium-induced disruption of neuroinflammatory pathways and gene regulation in Alzheimer’s disease pathogenesis

poster

Wagner, Monica S

Personalized iPSC-derived organoids for human Paneth cell modeling

poster

Wells, James M.

Engineering tissue complexity into human PSC-derived gastrointestinal organoids

talk

Whye, Dosh

Morphogen-directed, high-throughput development of hiPSC-derived telencephalic organoids for comparative in vitro phenotyping

poster

Wright, Phillip

Reproducible functional properties of brain organoids as a prelude to high-throughput drug screening

poster

Yamaguchi, Akihiro

Modeling the pathological brain–gut axis of Parkinson’s disease with a human iPSC-derived brain-gut assembloid

poster

Yang, Woo Sub

Comparative analysis of synchronized network activity in an epilepsy organoid model

poster

Zafeiriou, Maria Patapia P

Bioengineering of a human innervated and vascularized cardiac muscle model delineates neuronal contribution in KCNH2-related arrhythmias

talk

Zakharenko, Stanislav

Synaptic transmission and plasticity in human thalamocortical assembloids

talk

Zannino, Clara

Organoids vs connectoids—Modeling midbrain–striatal connectivity in vitro

poster

Zernicka-Goetz, Magdalena

Modeling human development beyond implantation using integrated stem cell-derived embryo models

talk

Zweigerdt, Robert

3D transcriptomic reconstruction highlights human heart-forming organoid development as a model of early organogenesis

talk