Advanced Sequencing Technologies & Applications
November 6 - 18, 2018
Application Deadline: July 15, 2018

Instructors:

Obi Griffith, Washington University School of Medicine
Malachi Griffith, Washington University School of Medicine
Elaine Mardis, Nationwide Children's Hospital Research Institute  
W. Richard McCombie, Cold Spring Harbor Laboratory
Aaron Quinlan, University of Utah

See the roll of honor - who's taken the course in the past

Over the last decade, massively parallel DNA sequencing has markedly impacted the practice of modern biology and is being utilized in the practice of medicine. The constant improvement of these platforms means that costs and data generation timelines have been reduced by orders of magnitude, facilitating investigators to conceptualize and perform sequencing-based projects that heretofore were time-, cost-, and sample number-prohibitive. Furthermore, the application of these technologies to answer questions previously not experimentally approachable is broadening their impact and application. However, data analysis remains a complex and often vexing challenge, especially as data volumes increase.

This intensive two week course will explore use and applications of massively parallel sequencing technologies, with a focus on data analysis and bioinformatics. Students will be instructed in the detailed operation of several platforms, including library construction procedures, general data processing, and in-depth data analysis. A diverse range of the types of biological questions enabled by massively parallel sequencing technologies will be explored including DNA re-sequencing of known cancer genes, de novo DNA sequencing and assembly of genomes, RNA-sequencing, and others that are tailored to the student's research areas of interest.

Cloud-based computing will also be explored. Guest lecturers will highlight unique applications of these disruptive technologies. We encourage applicants from a diversity of scientific backgrounds including molecular evolution, development, neuroscience, medicine, cancer, plant biology and microbiology.

2018 Guest Lecturers

Aravinda Chakravarti, NYU Langone
Debyani Chakravarty, Memorial Sloan Kettering Cancer Center
Ken Dewar, McGill University and Genome QC Innovation Centre, Canada
Brian Haas, Broad Institute
Ekta Khurana, Weill Cornell Medicine
Tuuli Lappalainen, New York Genome Center & Columbia University
Christopher Maher, Washington University School of Medicine
Sorana Morrissy, The Governors of The University of Calgary, Canada
Joseph Pickrell, New York Genome Center
Jan Witkowski, Cold Spring Harbor Laboratory



Support & Stipends

Major support provided by the National Human Genome Research Institute

Access to cloud computational resources may be supported by an AWS in Education Grant award from Amazon.

Stipends are available to offset tuition costs as follows:

       

US applicants (National Human Genome Research Institute)
Interdisciplinary Fellowships (transitioning from outside biology)  & Scholarships (transitioning from other biological disciplines) (Helmsley Charitable Trust)
International applicants (Howard Hughes Medical Institute)

Please indicate your eligibility for funding in your stipend request submitted when you apply to the course. Stipend requests do not affect selection decisions made by the instructors. 

Cost (including board and lodging): $3,885

No fees are due until you have completed the full application process and are accepted into the course. Students accepted into the course should plan to arrive by early evening on November 5 and plan to depart in the morning of November 18.

Before applying, ensure you have 1) Personal statement/essay; 2) Letter(s) of recommendation; 3) Curriculum vitae/resume (optional); 4) Financial aid request (optional). More details


If you are not ready to fully apply but wish to express interest in applying, receive a reminder two weeks prior to the deadline, and tell us about your financial aid requirements, click below: