|
Presenting Author |
Abstract Title |
Talk/Poster |
|
Adamson, Brittany |
Enabling scalable interrogation of rich single-cell phenotypes |
talk |
|
Aristizabal, Maria J |
High resolution time course analysis of Cdk8 depletion reveals a role for the mediator complex kinase subunit in glycolytic gene expression |
poster |
|
Banerjee, Abhimanyu |
Deep learning models of 422 C2H2 zinc finger transcription factor binding profiles reveal alternative DNA binding sequence preferences via combinatorial use of zinc fingers |
talk |
|
Barshad, Gilad |
Additive or redundant? Enhancer ensembles in the light of evolution |
talk |
|
Bartom, Elizabeth Thomas T |
Expression of exogenous mRNA in human cancer cell lines leads to RISC-mediated cell death |
poster |
|
Bellec, Maelle |
Decoding the function of mitotic bookmarking on transcriptional dynamics |
talk |
|
Beres, Thomas |
The nuts and bolts of NIH Peer Review |
poster |
|
Bhat, Pooja |
Profiling gene expression dynamics during early embryogenesis in zebrafish |
poster |
|
Blumberg, Amit |
Characterizing RNA stability genome-wide through combined analysis of PRO-seq and RNA-seq data |
poster |
|
Bonny, Alain |
Stress-induced transient cell cycle arrest coordinates metabolic resource allocation and balances adaptive tradeoffs |
talk |
|
Buck, Michael J |
Breaking into chromatin with p53/p63/p73 |
poster |
|
Buen Abad Najar, Carlos F |
A network of poison exons controls splicing factor expression during neurogenesis |
talk |
|
Bulyk , Martha |
MEDEA—Enrichment analysis of binding motifs for transcription factors in accessible chromatin |
poster |
|
Bulyk , Martha |
Transcriptional silencers in Drosophila serve a dual role as transcriptional enhancers in alternate cellular contexts |
talk |
|
Castro-Mondragon, Jaime |
Combining transcriptional and post-transcriptional regulation to predict mutations altering the gene regulatory program in cancer cells |
poster |
|
Catta-Preta, Rinaldo F |
Combinatorial transcription factor binding analysis reveals regulatory wiring in embryonic brain development and evolution |
poster |
|
Chappleboim, Alon |
Xrn1 depletion reveals the dynamics and limits of global mRNA homeostasis |
talk |
|
Cheemalavagu, Neha |
Integrated modeling approach for predicting macrophage functional states |
poster |
|
Chen, Kok Hao |
Highly specific multiplexed RNA imaging with split-fluorescence in situ hybridization |
talk |
|
Chiu, Tsu-Pei |
Modeling transcription factor-DNA binding with a multi-module deep learning framework |
talk |
|
Chou, Nigel |
Highly specific multiplexed RNA imaging with split-fluorescence in situ hybridization |
poster |
|
Chou, Shao-Pei |
Genetic dissection of the RNA polymerase II transcription cycle |
poster |
|
Crocker, Justin |
A mutagenesis survey of a developmental enhancer using automation and robotics reveals constraints on evolvability |
talk |
|
Danko, Charles |
Accurate imputation of histone modifications using transcription |
poster |
|
Davies, Philip R |
Understanding the interplay between mammalian cell growth and gene expression noise. |
poster |
|
Duttke, Sascha H |
Cooperative and spacing-dependent regulation of human transcription by diverse sequence-specific transcription factors |
poster |
|
Farhat, Dayana |
A MORC-driven transcriptional switch controls Toxoplasma developmental trajectories and sexual commitment |
poster |
|
Fernandez Fuentes, Narcis |
Identification of novel inhibitory peptides of TWEAK-Fn14 signaling pathway using PiPreD, a structure-based computational method. |
poster |
|
Findley, Anthony S |
Cell-type, environmental, and stochastic factors modulate genetic effects on gene transcription |
poster |
|
Friedman, Ryan Z |
Sequence features that specify enhancer and promoter activity |
talk |
|
Frost, Stephanie |
Cardiovascular disease-associated variants and their interplay with epigenomic enhancer conservation |
poster |
|
Gaye, Amadou |
Social disadvantage, gene expression and depressive symptoms in
African American from the Minority Health GRID Study |
poster |
|
Gebhardt, Christof |
Computer aided interactive gene network simulations including stochastic molecular kinetics and noise |
poster |
|
Gerstein, Mark |
An integrative ENCODE resource for cancer genomics |
poster |
|
Ghaffari, Saba |
Integrated analysis of multi-omics data to identify transcriptional regulators of cancer progression |
poster |
|
Giganti, David |
Visualizing the zinc finger – DNA landscape by the molecular parameters that define these interactions |
talk |
|
Gillis, Jesse |
The transcriptional legacy of developmental stochasticity |
talk |
|
Gordan, Raluca M |
Beyond DNA shape readout—The role of conformational penalties in protein-DNA recognition |
talk |
|
Goyal, Yogesh |
Elucidating biochemical trajectories guiding therapy resistance at the single cell level |
talk |
|
Gui, Yujuan |
The genetic and epigenetic architecture of axonal branching of substantia nigra dopaminergic neurons in the mouse |
poster |
|
Guo, Yue |
SunRISE—A labeling system for long-term imaging of single mRNA molecules in live cells |
talk |
|
Haigh, Alexandra |
Multi-omic temporal exploration of endometrial dynamics underlying the human implantation window |
poster |
|
Hait, Tom A |
Inferring cell type-specific enhancer-promoter interactions |
poster |
|
Hammell , Christopher |
BLMP-1 functions as a transcriptional rheostat to control gene dosage during larval development in C. elegans |
poster |
|
Hammelman, Jennifer L |
Identification of determinants of differential chromatin accessibility through a massively parallel genome-integrated reporter assay |
talk |
|
Hansen, Kasper B. |
Promoter CpG density is predictive of downstream gene loss-of-function intolerance |
poster |
|
Hardison , Ross |
An integrative view of the regulatory and transcriptional landscapes in mouse and human hematopoiesis |
poster |
|
Harris, Benjamin |
Multiscale co-expression in the brain |
poster |
|
He, Jin |
FGF/MAPK signaling links polycomb repressive complex 2 to regulate gene expression in mouse embryonic stem cells |
poster |
|
Honda, Mizuki |
High resolution spatial RNA-seq method focusing on photo-isolation chemistry |
talk |
|
Hook, Heather J |
CASCADE—A PBM-based platform to biophysically characterize enhancers and single-nucleotide polymorphisms (SNPs) |
poster |
|
Hoskins, Jason |
Expression and activity QTL analyses of phenotypic master regulators suggest downstream gene regulatory impacts of cardiometabolic GWAS signals in subcutaneous adipose tissue |
poster |
|
Hu, Shengen |
Broad CpG islands mark functionally important genes for priority in transcriptional regulation |
poster |
|
Huang, Wenrui |
Neuroinflammation characterizes the earliest changes in Alzheimer’s disease pathology and associated subjective cognitive impairment in adult hydrocephalus biopsies |
poster |
|
Hughes, Tim |
A diverse family of CGG binding proteins in Coelacanth produced by repeated integration of hAT transposons |
poster |
|
Jansen, Camden |
Pruning developmental gene regulatory networks using linked self-organizing maps |
poster |
|
Jin, Fulai |
DeepLoop robustly identifies enhancer-promoter interactions from low-depth and single-cell Hi-C data |
poster |
|
Jo, Leonardo |
Deciphering the mechanisms of LEAFY COTYLEDON1 (LEC1) as a transcriptional regulator of seed development |
poster |
|
Jolma, Arttu K |
AT hook DNA binding domains are highly abundant and evolve rapidly |
poster |
|
Jothi, Raja |
Bivalent chromatin does not poise genes for rapid activation |
talk |
|
Kang, Michelle |
Linking cis-regulatory regions using transcription factor binding signatures |
poster |
|
Kaplow, Irene M |
A guide to predicting activity of cis-regulatory element orthologs in hundreds of species |
talk |
|
Kim, Jun |
The role of condensin DC on 3D organization of X-chromosome in C. elegans |
poster |
|
Knaack, Sara A |
Dynamic regulatory module networks to study context-specific gene regulation |
poster |
|
Krebs, Arnaud R |
Single-molecule characterization of transcription factor cooperative binding at mouse cis-regulatory elements |
talk |
|
Krishnaswamy, Smita |
Detecting structure and patterns in big biomedical data |
talk |
|
Kumar, Vivek |
Transcriptome profiling and genome-scale metabolic modeling using Systems Biology Knowledgebase (KBase) |
poster |
|
Ladewig, Erik |
ARID1A mediated defects in mammary gland development |
poster |
|
Lareau, Liana F |
Coverage-dependent bias creates the appearance of binary splicing in single cells |
poster |
|
Laverty, Kaitlin U |
Sequence and structure preferences of RNA binding proteins |
talk |
|
Lee, Jiyoung |
Single cell transcriptome analysis characterizes low-grade non-resolving inflammation in mice monocytes |
poster |
|
Lee, Jun-Yeong |
Implication of CpG islands on transcriptional instability during aging |
poster |
|
Lenstra, Tineke |
Single-molecule imaging reveals the interplay between transcription factors, nucleosomes and transcriptional bursting |
talk |
|
Leviyang, Sivan |
Regulation of interferon stimulated genes at homeostasis |
poster |
|
Liang, Yue |
Klf4 is part of the cis-regulatory code leading to enhancer activation in mESCs |
poster |
|
Lou, Shaoke |
TopicNet—A framework for measuring transcriptional regulatory network change |
poster |
|
Mahajan, Tarun |
Internetwork connectivity of molecular networks across species of life |
poster |
|
Mahony, Shaun |
Hox binding specificity is directed by DNA sequence preferences and differential abilities to engage inaccessible chromatin |
talk |
|
Martinez-Ara, Miguel |
Systematic combinatorial testing of enhancer-promoter pairs. |
talk |
|
Meeuse, Milou |
Functional dissection of a gene expression oscillator in C. elegans |
poster |
|
Meuleman, Wouter |
Functional organization and compartmentalization of the accessible human genome |
poster |
|
Miao, Liyun |
Identification of the regulatory networks controlling chromatin remodeling during zygotic genome activation |
talk |
|
Miraldi, Emily |
Benchmarked strategies for transcriptional regulatory network inference from scRNA-seq |
poster |
|
Mouri, Kousuke |
Identification and characterization of repressive elements using MPRAduo |
talk |
|
Mylonas, Constantine |
A dual role for H2A.Z.1 in modulating Initiating and Elongating RNAPII dynamics |
talk |
|
Nair, Ajay |
Transcription factor protein-activity and binding-location inference |
poster |
|
Nameki, Robbin A |
Characterizing the core-regulatory circuitry in high-grade serous ovarian cancer and precursor normal fallopian tube cells |
poster |
|
Narykov, Oleksandr |
Functional dynamics of protein interactome induced by alternative splicing—An in silico approach |
poster |
|
Nollmann, Marcelo |
Through the looking-glass—Does DNA structure determine transcriptional activity? |
talk |
|
Nora, Elphege P |
Molecular basis of CTCF binding polarity in genome folding |
talk |
|
Noyes, Marcus B |
A massively parallel synthetic screen of finger-to-finger influences unlocks the code of zinc finger specificity and compatibility |
talk |
|
Nyquist, Sarah K |
Describing condition-specific gene modules in single-cell RNA-Seq with differential gene-gene correlation |
poster |
|
Oh, Jin Woo |
Sequence alignment using gapped-kmer composition identifies conserved orthologous mammalian enhancers with high precision |
poster |
|
Oliva, Baldo |
On the prediction of DNA-binding preferences of C2H2-ZF domains using structural models—Application on human CTCF |
poster |
|
Osmanbeyoglu, Hatice U |
Integrative computational framework for linking cell-specific signaling and transcriptional programs |
talk |
|
Parrello, Damien |
Widespread processing of nascent RNA in paused Pol II complexes is uncoupled from productive transcription |
talk |
|
Patel, Zain M |
Examining recognition models for vertebrate regulatory sequences |
poster |
|
Pazin , Mike J |
NHGRI funding opportunities |
poster |
|
Planells, Jordi |
Chromatin associated RNAs in Drosophila melanogaster—Identification and functional implications for maintenance of chromatin compaction |
poster |
|
Quintero Cadena, Porfirio |
RNA Pol II length and disorder enable cooperative scaling of transcriptional bursting |
talk |
|
Rahmanian, Sorena |
Robust method for long-read sequencing and quantification of metabolically labeled mRNAs |
poster |
|
Rama Pedro Alves, Mariana |
Multi-enhancer transcriptional hubs confer phenotypic robustness for developmental enhancers with variable binding affinities |
poster |
|
Rao, Satyanarayan |
In vivo mapping of transcription factor cooperativity at enhancers genome-wide |
talk |
|
Rebboah, Elisabeth |
Single nucleus RNA-seq and ATAC-seq of multinucleated skeletal muscle cells reveals priming of neuromuscular junction genes in the mouse C2C12 cell line |
poster |
|
Reed, Robert D |
cis-regulatory architecture of butterfly wing pattern evolution |
talk |
|
Rivera Barreto, Anthony R |
Determining the DNA binding preference of the transcription factor optix in Heliconius butterflies |
poster |
|
Rodriguez-Martinez, Jose A |
DNA-binding specificity of cardiac transcription factor complex of GATA4 and NKX2-5 |
poster |
|
Rosado-Tristani, Diego A |
Transcription factors in the order Lepidoptera |
poster |
|
Rumley, Jonathan D |
Regulation of anterior genes in the C. elegans embryo |
poster |
|
Sammons, Morgan A |
Parallel and non-redundant regulation of metabolic genes by master regulators of cell fate |
poster |
|
Sanford, Eric M |
How does a gene integrate two signals? |
poster |
|
Sauria, Michael |
Integrating DNA-sequence and epigenetic signals to predict differential chromatin topology |
poster |
|
Schubeler, Dirk |
A screen of mammalian transcription factor sensitivity to chromatin identifies a novel essential regulator of ribosomal protein genes |
talk |
|
Serizay, Jacques |
Distinct regulatory architectures of germline and soma genes in C. elegans |
poster |
|
Shigaki, Dustin T |
A method to identify transcription factor binding site motifs from DNA sequence based enhancer prediction models |
poster |
|
Shlyueva, Daria |
Integrated approach to study cell cycle-dependent chromatin dynamics |
poster |
|
Siao, Michelle |
An expansion in the C-terminal domain of the largest subunit of RNA polymerase II and maintenance of epigenetic memory in P. falciparum |
poster |
|
Sobreira, Debora |
Functionally dissecting the genetic landscape of complex human traits |
talk |
|
Song, Mengyi |
GATA5/6 broadly regulates the early specification of mesoderm lineages in zebrafish |
poster |
|
Staller, Max V |
Probing the sequence-to-function relationship of transcription factor activation domains |
talk |
|
Tabe Bordbar, Shayan |
Thermodynamics-based modeling of enhancer RNA transcription in breast cancer cells |
poster |
|
Taipale, Jussi |
Towards predicting gene expression from DNA sequence |
talk |
|
Tan, Xiangtian |
The TReK project—Large-scale knockdown of transcriptional regulators, at multiple timepoints, in human cell lines using an enhanced CRISPR repressor to improve gene-interaction networks |
poster |
|
Taskiran, Ibrahim I |
Deep learning and cross-species analysis on single-cell ATAC-seq data to decipher melanoma enhancer logic |
talk |
|
Tresch, Achim |
Nuclear RNA export is slower than expected—A comprehensive picture of RNA metabolism in HeLa cells |
poster |
|
Trizzino, Marco |
Human-specific SVA transposons rewired gene regulatory networks in the human hippocampus |
poster |
|
Vierstra, Jeffrey |
Chromatin dynamics during hematopoiesis reveal discrete regulatory modules instructing differentiation |
poster |
|
Wang, Li |
Elucidating functional enhancers governing pancreas cell identity |
poster |
|
Wang, Lingfei |
Normalisr—Statistical inference of gene regulations in single-cell transcriptomics |
poster |
|
Wang, Siyuan |
Multiplexed imaging of nucleome architectures in single cells of mammalian tissue |
talk |
|
Wang, Xiangxiu |
Inferring core transcriptional regulatory networks during zygotic genome activation in zebrafish |
poster |
|
Weaver, Kathryn J |
Predicting cis-regulatory element-gene pairing from epigenetic data in mouse hematopoiesis |
poster |
|
Weirauch, Matthew T |
Epstein-Barr virus EBNA2-driven gene dysregulation in autoimmune disease |
poster |
|
White, Michael A |
Flanking sequence elements define functional Crx binding sites in the genome |
poster |
|
Xi, Wang |
Loop extrusion model predicts CTCF interaction specificity |
talk |
|
Xiang, Guanjue |
S3norm—Simultaneous normalization of sequencing depth and signal-to-noise ratio in epigenomic data |
poster |
|
Yang, Hui |
Allele-specific DNA methylation and H3K9me3 blocks are critical for early embryo development |
poster |
|
Yu, Wenqiang |
Reactivation of tumor suppressor by enhancer switching through NamiRNA Network |
poster |
|
Zang, Chongzhi |
Cancer-specific CTCF binding facilitates oncogenic transcriptional dysregulation |
poster |
|
Zhang, Yuning |
Competition for DNA binding between paralogous transcription factors determines their genomic occupancy and regulatory functions |
poster |
|
Zhao, Rose |
CoRec—A high-throughput PBM platform for profiling active transcription factor-cofactor complexes in cells |
poster |
|
Zuo, Zheng |
A ‘picky tail’ model of embryonic stem cell fate regulation |
talk |