|
Presenting Author |
Abstract Title |
Talk/Poster |
|
Abdallah, Jad |
Targeting of HSPs in the malignant MYCN-amplified human neuroblastoma stem cells and therapeutic implications |
poster |
|
Adrados, Isabel |
ULK1 is a potential target in glioblastoma |
poster |
|
Agote Aran, Arantxa |
Fragile X syndrome proteins control localization of nucleoporins |
poster/rapid fire talk
|
|
Aivazidis, Stefanos |
Dysfunction of selective autophagy in DS models results in impaired clearance of autophagosome cargo. |
poster |
|
Alberti, Simon |
Phase separation as a stress survival strategy |
talk |
|
Ali, Maruf |
UPR proteins ‘switch and prime’ BiP from Chaperone to ER stress sensor |
talk |
|
Andreasson, Claes |
Regulation of Hsp70 by nucleotide exchange factors |
poster |
|
Arrieta, Adrian |
MANF, a structurally unique redox-sensitive chaperone, restores ER-protein folding in the ischemic heart |
poster |
|
Ayala, Yuna M |
Heat shock induced phosphorylation of TDP-43 by MAPK/ERK kinase regulates TDP-43 function and aggregation |
poster |
|
Baker, Jeremy D |
Prolyl isomerases dissolve neurotoxic tau aggregates |
poster |
|
Bastow, Emma L |
In vivo and in vitro analyses of the operation and control of yeast oxidative protein folding |
poster |
|
Baxter, Emily C |
CRISPR mutant of hspb8 in zebrafish establishes a model for myofibrillar myopathy |
poster/rapid fire talk |
|
Becker, Samuel H |
The Mycobacterium tuberculosis proteasome regulates nitrogen metabolism through an essential protein quality control system |
poster |
|
Bell, Tristan A |
Hinge regions of a AAA+ protein unfoldase mediate efficient intersubunit communication during substrate processing |
poster/rapid fire talk |
|
Bennett, Eric J |
Examining the ubiquitin-dependence of stress granule dynamics and diversity |
talk |
|
Benyair, Ron |
GM130 interacts with GRASP proteins to avoid proteasomal degradation |
poster |
|
Bergink, Steven |
Collapse in protein homeostasis is a crucial intermediate of genome instability related neurodegeneration |
talk |
|
Bezsonov, Evgeny |
Factors affecting curing of [URE3] prion by Btn2 and Cur1 proteins |
poster |
|
Bhattacharya, Kaushik |
The common cofactor HOP of HSP70 and HSP90 balances the cellular equilibrium between folding and degradation |
poster |
|
Biverstal, Henrik |
Improved overexpression of amyloidogenic peptides by solubility enhancer from spider silk |
poster |
|
Boczek, Edgar E |
Molecular chaperones control the physical state of membrane-less compartments |
talk |
|
Brambilla Pisoni, Giorgia |
Palmitoylation controls turnover of ER resident membrane proteins |
poster |
|
Brandman, Onn |
Quantitative analysis of Hsp90 availability and the Heat Shock Response under proteotoxic stress |
talk |
|
Braun, Janice E |
Characterization of the CSPα-EV export pathway |
poster |
|
Brennan, Christopher M |
Aneuploidy reveals insights into stoichiometric imbalance control |
talk |
|
Buchner, Johannes |
Functional principles of the Hsp90 chaperone machinery |
talk |
|
Bukau, Bernd |
Co-translational interactions of nascent chains revealed by ribosome profiling |
talk |
|
Camberg, Jodi L |
Site-specific mutations in the Hsp104 N-domain prevent [PSI+] curing in Saccharomyces cerevisiae |
poster |
|
Carra, Serena |
Aberrant compartment formation by HSPB2 mislocalizes lamin A and compromises nuclear function—Implication for neuromuscular diseases |
poster |
|
Carra, Serena |
Protein quality control of stress granules |
talk |
|
Carroll, Courtney |
Elucidating the role of small heat shock protein 25 in protein aggregation |
poster |
|
Chakraborty, Kausik |
Metabolic rewiring regulates mutational buffering by altering proteostasis |
poster |
|
Chatterjee, Bhaskar K |
KU-32, a Novobiocin analogue, acts as a stimulator of Hsp90 in-vitro |
poster |
|
Chen, Chien-Wen |
Genome-wide translation profiling by ribosome-bound tRNA capture |
poster/rapid fire talk |
|
Chen, Gefei |
Three activities from one chaperone domain—Client specificity of Bri2 BRICHOS is governed by quaternary structure |
poster |
|
Chen, John |
CRISPRi-based Identification of trafficking factors that control Tau aggregation in a cell-based model |
poster |
|
Chinchankar, Meghna N |
The adapted endoplasmic reticulum (ER)-associated protein quality control (ERQC) is critical for the long-lived Caenorhabditis elegans rpn-10 proteasomal mutant |
poster/rapid fire talk |
|
Ciryam, Prashanth |
An automated approach to RNAi screening in Caenorhabditis elegans to identify a gene signature of Alzheimer’s disease |
poster |
|
Clerico, Eugenia M |
Novel aspects of substrate binding emerge from detailed studies of bacterial Hsp70-client complexes |
poster |
|
Collart, Martine |
Co-translational assembly of proteasome subunits in Not1-containing assembylsomes |
poster |
|
Conn, Crystal S |
Development of a stress response therapy targeting protein synthesis in aggressive prostate cancer |
talk |
|
Couto, Paula M |
Study of the molecular determinants that regulate the efficiency of protein N-glycosylation |
poster |
|
Dahiya, Vinay |
Chaperoning of p53 by Hsp70 and Hsp90 |
poster/rapid fire talk |
|
Dai, Chengkai |
HSF1 is an intrinsic master AMPK antagonist through physical interactions |
poster |
|
Dayalan Naidu, Sharadha |
Transcription factors NRF2 and HSF1 have opposing functions in autophagy |
poster |
|
Deuerling, Elke |
Plasticity of ribosome-associated chaperones |
talk |
|
Deville, Celia |
Structural pathway of regulated substrate transfer and threading through the Hsp100 disaggregase ClpB |
poster |
|
Dey, Madhusudan |
Proteostasis regulation by Kin kinases in Saccharomyces cerevisiae |
poster |
|
Dobson, Christopher |
The amyloid state of proteins and its significance in human disease |
talk |
|
Dodt, Christopher |
The co-chaperone Cns1 affects translation elongation |
poster |
|
Douglas, Peter M |
Opposing activities of mechanical stress response pathways induced trauma-induced neurodegeneration |
poster |
|
Doyle, Shannon M |
The surfaces involved in the direct interaction between Hsp70 and Hsp90 are conserved in bacteria and yeast |
poster |
|
Drummond, D. Allan |
Reversible, selective, adaptive demixing of mRNA during stress |
talk |
|
Du, Zhen |
Probing protein homeostasis mechanisms in long-lived naked mole-rats and its relationship with human diseases |
poster/rapid fire talk |
|
Dublin, Leeran B |
The effects of chaperone availability, environmental stress, and translation rate on co-translational protein folding and prion formation |
poster/rapid fire talk |
|
Eisenberg, David |
LARKS link low-complexity domains to form networks in protein gels and membrane-less assemblies. |
talk |
|
Elam, William A |
Biophysical characterization of chimeric antigen receptor rheostats |
poster |
|
Farnen, Chelbee M |
The role of HSP-12.6 in lifespan and health span of C. elegans |
poster |
|
Freeman, Brian C |
Chromosome motion within interphase nuclei is a molecular chaperone-dependent pathway involving chromatin remodelers and nuclear actin |
talk |
|
Frost, Adam S |
Vms1p is a release factor for the ribosome-associated quality control complex |
talk |
|
Gaglia, Giorgio |
An unexpected relationship between HSF1 foci dynamics and HSF1 function |
poster/rapid fire talk |
|
Garshott, Danielle M |
USP21 and OTUD3 antagonize regulatory ribosomal ubiquitylation and ribosome-associated quality control pathways |
poster |
|
Gelis, Ioannis |
Phosphorylation induced cochaperone unfolding promotes kinase recruitment and client class-specific Hsp90 phosphorylation |
poster |
|
Gidalevitz, Tali |
Target-specific rather than global effects on ER folding homeostasis explain neuron-selective dysfunction in a model of conformational disease |
talk |
|
Gierasch, Lila |
Exploring functional properties of Hsp70 molecular machines |
talk |
|
Girstmair, Hannah |
Chaperoning of the phosphatase calcineurin by Hsp90 |
poster |
|
Glynn, Steven E |
Structure of the mitochondrial protease AFG3L2 reveals the molecular underpinnings of spastic paraplegia |
poster |
|
Gomez-Pastor, Rocio |
Neuronal HSF1 degradation is activated by p53 in Huntington´s disease |
poster |
|
Goncalves, Conrado de Campos |
Phosphorylated human HspB1 is involved in disaggregation activity with Hsp70-Hsp40 system |
poster |
|
Good, Sarah |
Understanding the proteotoxic mechanism of amyloidogenic proteins in vivo—C. elegans models of systemic amyloidosis and diabetes mellitus |
poster/rapid fire talk |
|
Grandjean, Julia M |
Discovering novel small molecule activators of the Ire1α/XBP1s signaling pathway |
poster |
|
Greene, Lois |
Real-time imaging of yeast cells reveals several distinct mechanisms of curing of the [URE3] prion |
poster |
|
Guan, Bo-Jhih |
PERK sustains amino acid homeostasis during chronic endoplasmic reticulum stress |
poster |
|
Hallacli, Erinc |
yTRAP—A genetic tool to measure protein solubility in vivo |
poster |
|
Hartl, F. Ulrich |
Chaperone functions in protein folding and proteome maintenance |
talk |
|
Hayer-Hartl, Manajit |
Putting plant RuBisCO together in E. coli |
talk |
|
Heider, Michael |
Immunomodulatory drugs disrupt CRBN and HSP90-mediated stabilization of CD98hc and LAT1 to interfere with tumor metabolism |
poster |
|
Hickey, Kelsey L |
Role of the mammalian ribosome quality control complex (RQC) in proteostasis |
poster |
|
Hipp, Mark S |
High capacity of the endoplasmic reticulum to prevent secretion and aggregation of amyloidogenic proteins |
talk |
|
Hoppe, Thorsten |
Olfactory food perception rewires organismal proteostasis |
talk |
|
Houry, Walid A |
Novel features of the chaperone cellular network revealed through systematic interaction mapping |
talk |
|
Huck, John |
The pre-N domain is a distinct feature of Grp94 that is essential for client maturation and regulation |
poster |
|
Hunt, Liam |
i>Drosophila genetic screening uncovers UBR4, an E3 ubiquitin ligase, as an evolutionary conserved negative regulator of skeletal muscle growth but a necessary component of protein homeostasis |
poster |
|
Iburg, Manuel |
Non-canonical sHsps in metazoan organisms |
poster |
|
Itoh, Hideaki |
Study on cancer stem cell formation of cancer cells |
poster |
|
Jackrel, Meredith |
Potentiated Hsp104 variants counter protein misfolding underpinning neurodegenerative disease |
poster |
|
Jakob, Ursula |
Effects of developmental ROS production on stress resistance and lifespan |
talk |
|
Jiang, Yajun |
Structural basis for the client recognition and holding of molecular chaperone Hsp40 |
poster |
|
Jin, Mingliang |
Ensemble of cryo-EM structures of eukaryotic chaperonin TRiC/CCT reveals its stepwise ring closure mechanism |
poster |
|
Joachimiak, Lukasz A |
Tau aggregation is regulated by local β-hairpin structure |
poster |
|
Johansson, Jan |
One chaperone domain, two amyloid diseases and three assembly states |
talk |
|
Joshi, Abhinav |
Mitochondrial metabolic homeostasis may be regulated by a TRAP1 containing multi-chaperone complex |
poster |
|
Kaiser, Christian M |
Dual chaperone function in nascent protein folding |
talk |
|
Kampmann, Martin |
Uncovering cellular mechanisms controlling tau aggregation, prion-like spread and toxicity using CRISPR-based genome-wide screens in human neurons |
talk |
|
Kandola, Tejbir S |
Measuring nucleation barriers in vivo reveals the physical basis of prion-like phase behavior |
poster/rapid fire talk |
|
Kao, Chung-Hsuan |
ATM directs DNA damage responses and proteostasis via genetically separable pathways |
poster |
|
Kawahara, Hiroyuki |
A pathway for the cytoplasmic removal of mislocalized transmembrane domain proteins though BAG6 complex |
poster |
|
Kayatekin, Can |
Translocon declogger Ste24/ZMPSTE24 protects against IAPP oligomer-induced proteotoxicity |
talk |
|
Kirstein, Janine |
Identification of distinct chaperone complexes that suppress Htt fibrilization and disaggregate Htt amyloid fibrils |
poster |
|
Klaips, Courtney L |
An Hsp40 enables recognition of pathological protein aggregation and stress response activation. |
poster/rapid fire talk |
|
Kleinridders, Andre |
Gender-specific differences of reduced Hsp60 expression in the development of obesity |
poster |
|
Klevit, Rachel |
Pinning jello to spaghetti—Structural studies of the dynamic, heterogeneous chaperone HSPB1 and interactions with its disordered client tau |
talk |
|
Kong, Ka-Yiu Edwin |
Optimal heat shock induced expression of the Sis1 chaperone requires the Hsf1-independent degradation of the RNA quality control factor Dis3 which normally suppresses protein quality control activity by specifically degrading the Sis1 mRNA |
poster |
|
Kravats, Andrea N |
A conserved region in the middle domain of yeast Hsp90 is important for physical and functional interaction with Hsp70 and Hsp90 co-chaperones |
poster |
|
Kruyt, Frank |
The unfolded protein response sensor PERK regulates glioblastoma stem cell self-renewal capacity and involves post-transcriptional control of SOX2 expression |
poster |
|
Kulathu, Yogesh |
Regulation of protein degradation by MINDY DUBs |
poster |
|
Kumar, Jyotsna |
Human DnaJB6 mediated protection from poly glutamine toxicity in yeast |
poster |
|
Kumar, Shailesh |
Mutations outside of Ure2 amyloid-forming region disrupt [URE3] prion propagation by different mechanisms |
poster |
|
Kundra, Rishika |
Homeostasis of metastable proteins in Alzheimer’s disease |
poster |
|
Leppert, Axel |
Bri2 BRICHOS assembly and activity is regulated by redox conditions |
poster |
|
Li, Jing |
Epidithiodiketopiperazines inhibit protein degradation by targeting proteasome deubiquitinase Rpn11 |
poster |
|
Li, Weihan |
Regulating ER protein homeostasis by differentially processing mRNAs |
talk |
|
Lindberg, Iris |
Intranigral overexpression of the neural/endocrine chaperone proSAAS attenuates Parkinson’s symptoms in a rat PD model |
poster |
|
Lissemore, James |
HSP90 co-chaperones promote GLP-1/Notch signaling during C. elegans embryogenesis |
poster |
|
Liu, Caixuan |
Yeast TRiC/CCT single subunit forming homo-oligomers reveals subunit individual specialty and give hints on the TRiC cooperative mechanism |
poster |
|
Lorenz, Robin |
Dimerization control of the E3 ligase CHIP in substrate selection and processing |
poster |
|
Mabanglo, Mark F |
Dysregulation of human mitochondrial ClpP protease activity by acyldepsipeptides leads to apoptotic cell death |
poster |
|
Majtan, Tomas |
Disruption of protein folding machinery by pathogenic cystathionine beta-synthase mutants |
poster |
|
Mandal, Atin K |
HSP70/HSP40/NEF chaperone complex determines the fate of misfolded cytosolic protein |
poster |
|
Margittai, Martin |
Molecular basis for seeding barriers between three- and four-repeat tau |
poster |
|
Marinko, Justin |
Identification of the factors that mediate plasma membrane trafficking of peripheral myelin protein 22 |
poster |
|
Marshall, Richard S |
Autophagic degradation of 26S proteasomes is regulated by multiple ubiquitylation and aggregation events |
talk |
|
Masser, Anna E |
Misfolded proteins modulate amplitude and genetic profile of the heat shock response |
poster |
|
Matlahov, Irina |
Structure and dynamics of DNAJB8 co-chaperones in their oligomeric state |
poster/rapid fire talk |
|
Mayer, Matthias |
Molecular mechanism of the mammalian heat shock transcription factor HSF1 |
talk |
|
Mayor, Thibault |
Investigation of the composition and formation of heat stress granules |
talk |
|
Meng, Wenli |
Evolutionary tuning of Hsp70 molecular chaperones—The allosteric landscape of the stress-inducible human Hsp70, HspA1 |
poster |
|
Merbl, Yifat |
Golgi integrity is regulated via localized proteasomal degradation |
poster |
|
Mercier, Rebecca J |
Searching for the Aha moment—How do the Aha-type co-chaperones regulate Hsp90? |
poster |
|
Meyer, Hemmo |
AP-SWATH reveals direct involvement of VCP/p97 in integrated stress response signaling |
poster |
|
Mogk, Axel |
Unique molecular features define the stand-alone ClpG disaggregase |
poster |
|
Mollapour, Mehdi |
Tumor suppressor Tsc1 is a new Hsp90 co-chaperone that facilitates folding of kinase and non-kinase clients |
poster |
|
Monteiro, Mervyn |
Early collapse of proteostasis in UBQLN2 mouse models of ALS/FTD |
talk |
|
Morimoto, Richard |
Proteostasis of aging and disease |
talk |
|
Murray, Dylan T |
A molecular view of RNA granule assembly |
poster |
|
Nagata, Kazuhiro |
Redox-mediated regulation of ER homeostasis |
talk |
|
Neckers, Len |
HSP90 inhibitors disrupt a transient HSP90-HSF1 interaction and identify a noncanonical model of HSP90-mediated HSF1 regulation |
talk |
|
Noxon, Isabelle C |
The role of PERK in secretory proteostasis |
poster |
|
Nystrom, Thomas |
A genome-wide screen revealing new players required for the formation and clearance of protein inclusions |
talk |
|
Ohsumi, Yoshinori |
Lessons from yeast—As a cellular recycling system |
talk |
|
Pal, Mohinder |
Cryo-EM structure of the R2TP complex, a co-chaperone of HSP90 |
poster |
|
Panhelainen, Anne E |
Alpha-synuclein fibril -seeded progressive pathology in mouse neurons can be affected by interfering with the internalization of the fibrils or by regulation of UPR |
poster |
|
Pankow, Sandra |
A new, post-translational modification–dependent mechanism for recognizing misfolded proteins |
poster |
|
Parajuli, Nirmala |
Renal cold storage followed by transplantation impairs proteasome function and mitochondrial protein homeostasis |
poster |
|
Patton, Kyle A |
Uncovering the role of Hsp40 chaperone family members in the formation and persistence of long-term memory |
poster |
|
Piette, Benjamin L |
Comprehensive characterization of the human Hsp70/Hsp40/client interactome |
poster/rapid fire talk |
|
Pincus, David |
Hsf1 and Hsp70 constitute a two-component feedback loop that regulates the yeast heat shock response |
talk |
|
Pinheiro, Glaucia S |
NMR structure of the J-domain of co-chaperone Sis1 from Saccharomyces cerevisiae |
poster |
|
Plate, Lars |
Proteostasis interactome remodeling revealed by multiplexed TMT-quant affinity purification-mass spectrometry |
poster |
|
Popova, Katerina D |
The ER membrane protein complex (EMC) interacts co-translationally to enable biogenesis of multipass membrane proteins |
poster |
|
Pradet-Balade, Berengere |
The HSP90> R2TP>TTT system folds and assembles distinct clients
to control intestinal homeostasis |
poster |
|
Price, John C |
Creating a proteome-wide mechanistic description of protein homeostasis |
poster |
|
Quan, Shu |
The disordered N-terminus of Spy drives substrate release |
poster |
|
Rai, Manish K |
Understanding the molecular mechanism of adaptive thermotolerance in E.coli |
poster |
|
Rainbolt, Kelly |
Neural stem cell proteostasis is rewired upon differentiation and aging |
poster |
|
Ramachandran, Kapil |
Activity-dependent and ubiquitin-independent degradation of the nascentome by the neuronal membrane proteasome |
poster/rapid fire talk |
|
Raman, Malavika |
Protein quality control at the ER by the VCP-UBXN1 complex |
poster |
|
Richter, Uwe |
Mitochondrial nascent chain proteotoxicity remodels membrane morphology and attenuates translation |
poster |
|
Rizzolo, Kamran D |
Centrality of molecular chaperones in the global yeast genetic interaction network |
poster |
|
Rodriguez-Fernandez, Imilce A |
Nrf2 engages a proteostatic checkpoint in intestinal stem cells |
poster |
|
Ron, David |
Short-term mechanisms that maintain protein folding homeostasis in the endoplasmic reticulum |
talk |
|
Russo, Claudia |
Dissecting the effects of p63 mutant protein misfolding and aggregation on protein homeostasis in AEC syndrome |
poster |
|
Ryu, Seung Woo |
Systematic identification of HSP70 chaperone clients |
poster |
|
Sachsenhauser, Veronika |
Genetic selection for isolation of protein folding factors in Saccharomyces cerevisiae |
poster |
|
Sarraf, Shireen |
The autophagy receptor protein, TAX1BP1, mediates clearance of stress-induced protein aggregates |
poster/rapid fire talk |
|
Satapathy, Sandeep |
Deciphering the structure-function relationship of clusterin—The first known mammalian extracellular chaperone |
poster |
|
Sato, Atsuko |
Role of DnaJ in developmental robustness and canalization |
poster |
|
Sawarkar, Ritwick |
Mechanism of transcriptional downregulation in response to proteotoxic stress |
talk |
|
See, Stephanie K |
Identification of cellular mechanisms that control α-synuclein aggregation using a CRISPRi/a functional genomics platform |
poster |
|
Shinohara, Kyosuke |
Splitting of the Hsp104 disaggregase revealed by near atomic analysis and direct visual observation |
talk |
|
Shoulders, Matthew D |
Immune escape by the 1918 flu relies on host chaperones and the heat shock response |
talk |
|
Si, Kausik |
Encoding memory in protein conformation |
talk |
|
Signer, Robert |
Hematopoietic stem cells are particularly dependent on the maintenance of protein homeostasis |
poster |
|
Silva, Catarina |
Experimental therapeutics for autophagy-mediated rescue of Tauopathy phenotypes in human neuronal cell models |
talk |
|
Singh, Rajesh K |
Deciphering the ubiquitin code with poly-ubiquitin chain selective affinity matrices |
poster |
|
Sistonen, Lea |
Synergistic and opposite effects of HSFs in cell stress and cancer - a novel role for HSF2 in cell-cell adhesion |
talk |
|
Soares, Ana R. |
Identifying novel proteostasis regulators in health and disease |
poster |
|
Sommer, Thomas |
MuRF1 is a muscle specific subunit of a Cul4A ubiquitin ligase required for muscle atrophy |
talk |
|
Song, Dongyan |
PTPN23 sustained acute myeloid leukemia (AML) survival through regulation of protein homeostasis. |
poster |
|
Sontag, Emily M |
Sorting out the JUNQ—The spatial nature of protein quality control |
talk |
|
Southworth, Daniel |
The mechanism of protein disaggregation by Hsp100 AAA+ machines |
talk |
|
Stein, Kevin C |
Translation kinetics and co-translational proteostasis in health and disease |
poster/rapid fire talk |
|
Strieter, Eric R |
Ubiquitin chain debranching regulates proteasomal degradation |
poster |
|
Sui, Xiao-Jing |
Understanding how proteostasis maladaptation relates to proteome aggregation under diverse proteostasis stresses |
poster/rapid fire talk |
|
Sunde, Margaret |
Formation of functional amyloid fibrils by viral proteins that inhibit host cell necroptosis |
talk |
|
Taguchi, Hideki |
Intrinsic ribosome destabilization underlies translation and provides an organism with a strategy of environmental sensing |
talk |
|
Tanaka, Motomasa |
Molecular basis for diversification of yeast prion strain conformation |
poster |
|
Truttmann, Matthias C |
Chaperone AMPylation modulates aggregation and toxicity of neurodegenerative disease-associated polypeptides |
talk |
|
Tsai, Francis T |
Three-dimensional Structures of the Hsp104 hexamer in the ATP-bound state |
talk |
|
Tsuchiya, Yuichi |
IRE1-XBP1 pathway regulates oxidative proinsulin folding in pancreatic beta cells |
poster |
|
Tye, Blake W |
Heat shock factor 1 monitors the integrity of ribosome assembly |
poster/rapid fire talk |
|
van der Wel, Patrick C |
Supramolecular polymorphism in Huntington’s disease protein aggregates |
poster |
|
van Oosten-Hawle, Patricija |
A PQM-1-mediated response triggers transcellular chaperone signalling and regulates organismal proteostasis in C. elegans |
poster |
|
Vanderperre, Benoît |
Identification of genetic modifiers of alpha-synuclein aggregates intracellular accumulation |
poster |
|
Veenhoff, Liesbeth |
The challenge of making and maintaining large complexes - Nuclear pores in replicative ageing |
poster |
|
Venkatesan, Shriram |
Exploring the interplay between protein translation and stress granules in affecting nucleated aggregation |
poster |
|
Walti, Marielle A |
Towards the understanding of how Hsp60 interacts with amyloidogenic peptides and inhibits neurodegenerative diseases |
poster |
|
Wang, Ray |
The architecture of the Hsp90:Hsp70:Hop:GR complex in a pre-hydrolysis state |
talk |
|
Wang, Yu-Chun |
Hsp90 mediates membrane deformation and exosome release |
poster |
|
Wanker, Erich |
Proteotoxic seeding-competent amyloid aggregates in Huntington's disease |
talk |
|
Weissman, Jonathan S |
The EMC interacts co-translationally to chaperone biogenesis of multi-pass membrane proteins |
talk |
|
Whiteley, Alexandra M |
Proteomics of multiple Ubqln2-mediated mouse models of ALS reveals new client proteins and potential pathways of disease development |
poster/rapid fire talk |
|
Wieteska, Luksaz |
Molecular mechanisms of post-translational regulation for the ER molecular chaperone BiP |
poster |
|
Willardson, Barry M. |
Role of the cytosolic chaperonin CCT in the assembly of mTOR complexes |
poster |
|
Wiseman, Luke C |
Correcting proteostasis defects through pharmacologic activation of the unfolded protein response-associated transcription factor ATF6 |
talk |
|
Wolmarans, Annerieke |
Dissecting the asymmetric regulation of Hsp90 ATPase activity |
poster |
|
Wu, Jianzheng |
Characterize self-assembly propensities of Aβ42 mutants in live cells |
poster |
|
Xie, Lihan |
Subcellular localization, uptake and dynamics of inorganic polyphosphate in mammalian cells |
poster |
|
Yan, Xiao |
GroEL ring separation and exchange in the chaperonin reaction |
poster |
|
Ye, Xiang |
The action of molecular machines revealed by HX-MS |
poster |
|
Yen, Hsueh-Chi |
C-terminal end-specific elimination of aberrant proteins by CRL2 ubiquitin ligases |
poster |
|
Yohda, Masafumi |
Expression and characterization of the Plasmodium translocon of the exported proteins |
poster |
|
Young, Jason |
Hsp110 is a modulator of Hsp70 function |
poster |
|
Zhang, Tao |
Investigating Aβ and D-peptide interactions in the low-micromolar to nanomolar concentration range |
poster |
|
Zhao, Rongmin |
Exploring the role of 19S regulatory particle in mediating ubiquitin-independent protein degradation by the 26S proteasome |
poster |