|
Presenting Author |
Abstract Title |
Talk/Poster |
|
Abd Wahab, Syafiq |
Reconstitution of replication-coupled CAF-1-dependent nucleosome assembly |
poster |
|
Abid Ali, Ferdos |
Cryo-EM structure of a licensed origin of replication and mechanism for duplex DNA untwisting by the CMG |
poster |
|
Ackerson, Stephanie M |
Conditional knockout of CTC1 elicits a global DNA damage response and cell cycle arrest |
poster |
|
Aharoni, Amir |
Live cell measurements of eukaryotic DNA replication rates |
poster |
|
Alabert, Constance |
Histone modifications—Monologue and dialogue behind replisomes |
poster |
|
Alamdjem, Mirit l |
Chromatin interacting proteins modulate replication initiation events at replication origins |
talk |
|
Alvarez, Vanesa |
DNA damage tolerance is down-regulated at replication forks in an asymmetrical manner |
poster |
|
Amin, Aftab |
An essential, cell cycle-dependent and semi-conservative ORC dimerization cycle critically regulates DNA replication |
poster |
|
Anastassiadis, Theonie |
Genome-wide characterization of replication fork collapse sites from ATR and WEE1 inhibition reveals similar and function-specific features |
poster |
|
Appanah, Rowin |
Analysis of the role of the DNA/RNA helicase Sen1, a replisome component, at the interface of DNA replication and transcription |
poster |
|
Araki, Hiroyuki |
Structure and function of the Sld3-Sld7 complex essential for the initiation of chromosomal DNA replication |
talk |
|
Araujo, Christiane |
Features of DNA replication in Trypanosoma cruzi—From origin identification to nucleosome occupancy |
poster |
|
Armstrong, Robin L |
Whole genome replication timing profiling in Drosophila histone tail mutants reveals an uncoupling between transcription and DNA replication |
poster |
|
Audit, Benjamin |
A natural model for the universality of DNA replication kinetics |
poster |
|
Aze, Antoine |
RNAs coordinate nuclear envelope assembly and DNA replication through ELYS recruitment to chromatin |
poster |
|
Balasov, Maxim L |
The role of ORC6 in septin complex functions in Drosophila |
poster |
|
Balmus, Gabriel |
Non-homologous end-joining drives toxic DNA repair in the absence of the ATM tumor suppressor |
talk |
|
Barbon, Marta |
Understanding the role of Mcm5 C-terminus during helicase loading |
poster |
|
Bass, Thomas E |
ETAA1 activates ATR to maintain genome integrity |
poster |
|
Baxley, Ryan M |
Progressive genomic instability and telomere erosion in human cells following inactivation of a single MCM10 allele |
talk |
|
Bellush, James M |
Novel roles for gene enhancers and DNA replication origins in organizing the zygotic genome during C. elegans embryogenesis |
poster |
|
Bergoglio, Valerie |
Replication stress influences the timing of DNA replication initiation of the next cell generation |
poster |
|
Bermejo, Rodrigo |
Cohesin ubiquitylation and mobilization promotes stalled replication fork dynamics and integrity |
poster |
|
Bezalel Buch, Rachel |
The control of eukaryotic mutagenesis by Rev1 and DNA polymerase ζ |
poster |
|
Billing, David L |
The phospho-recognition activities of the BRCT domains of BRCA1 and BARD1 are required for protection of stalled replication forks by the BRCA1/BARD1 heterodimer |
poster |
|
Bochman, Matthew L |
Using bacterial PIF1 helicases to determine the functions of the non-conserved domains of their eukaryotic homologs |
poster |
|
Boos, Dominik |
MTBP shows homology with yeast Sld7 in sequence and function, and also has vertebrate-specific features |
talk |
|
Brannvoll, Andre |
From yeast to human—Identification of ZGRF1 as a novel DNA repair factor |
poster |
|
Branzei, Dana |
DDK-mediated regulation of the deSUMOylating enzyme Ulp2 facilitates early steps of DNA replication |
talk |
|
Brossas, Caroline |
Building synthetic early replicating units in a naturally mid-late region involves cooperation between shifting modules |
poster |
|
Brown, Eric J. |
Replication fork collapse from checkpoint inhibition |
talk |
|
Bui, Duyen |
Re-replication induces point mutations in Saccharomyces cerevisiae |
poster |
|
Buisson, Remi |
Coupling of homologous recombination and the checkpoint by ATR |
poster |
|
Bunting, Samuel F |
53BP1 is required for the normal cellular response to replication stress |
talk |
|
Burnham, Daniel R |
The eukaryotic replicative helicase, CMG, unwinds DNA as a lazy Brownian ratchet |
poster |
|
Cantor, Sharon |
New roles for the BRCA-FA pathway in the replication stress response |
talk |
|
Carvajal Maldonado, Denisse C |
Pds5 sister chromatid cohesion protein facilitates DNA replication fork progression |
poster |
|
Cerritelli, Susana |
Processing of R-loops by RNases H and the RNA exosome |
poster |
|
Chakraborty, Arijita |
Fragile X mental retardation protein (FMRP) promotes genome stability through R-loop regulation |
talk |
|
Chang, Emily |
Understanding the role of DNA repair factors in regulating R-loop-mediated genome instability |
poster |
|
Chen, Chi-Fu |
Pif1 family helicases regulate replication and function of budding yeast centromeres |
poster |
|
Chen, Chunlong |
Replication incompleteness under replication stress is crucial to CFS instability |
talk |
|
Cheng, Gang |
Temporospatial coupling of meiotic replication and DSB formation in mammals |
poster |
|
Chesnokov, Igor |
The structural and functional analysis of the Orc6 protein—Drosophila model of the Meyer-Gorlin syndrome |
poster |
|
Chistol, Gheorghe |
Single molecule visualization of CMG dynamics during replication in Xenopus egg extracts |
poster |
|
Chowdhury, Dipanjan |
TIRRing 53BP1 away from chromatin |
talk |
|
Ciccia, Alberto |
Restoration of fork stability in BRCA1- and BRCA2-deficient cells |
talk |
|
Clijsters, Linda |
Cyclin F-mediated degradation of E2F1, E2F2, and E2F3A controls mitotic cell cycles as well as endocycles |
poster |
|
Cong, Ke |
BRCA-Fanconi anemia and mismatch repair pathways are linked to coordinate the replication stress response |
poster |
|
Cook, Jean |
Rapid replication origin licensing protects stem cell pluripotency |
poster |
|
Cortez, David K |
RADX promotes genome stability and modulates chemosensitivity by regulating RAD51 at replication forks |
talk |
|
Coster, Gideon |
Bidirectional eukaryotic DNA replication is established by quasi-symmetrical helicase loading |
poster |
|
Coulombe, Philippe |
ORC ubiquitylation mediated by Obi1 is required for efficient replication origin firing |
talk |
|
Cutler, Samuel |
Roles for the ATP-dependent chromatin remodeling factors Isw2 and Ino80 in regulating replication origin activity and copy number control at the ribosomal DNA locus |
poster |
|
Daddacha, Waaqo |
SAMHD1 promotes DNA end resection to facilitate DNA repair by homologous recombination |
poster |
|
De Jesus-Kim, Lorraine |
Nanobodies targeting ORC and Mcm2-7 inhibit replicative helicase loading |
poster |
|
de Lima, Loyze |
DNA polymerase θ helicase domain negatively regulates DNA replication in Trypanosoma cruzi |
poster |
|
De Piccoli, Giacomo |
How do replication forks deal with transcription? Analysis of the interaction of the DNA/RNA helicase Sen1 with the replisome and its role in genome stability |
talk |
|
Debatisse, Michelle |
CDK1 activity determines CFS instability by controlling origin firing in late domains |
talk |
|
Deegan, Tom D |
Reconstituting DNA replication termination with purified proteins |
talk |
|
Dekker, Nynke H |
Studies of DNA unwinding by eukaryotic replicative helicases using high-throughput single-molecule techniques |
poster |
|
Delamarre, Axel |
Chromatin dynamics promotes stalled replication forks processing and cohesin loading |
poster |
|
Deng, Lin |
Mitotic CDK induces replicative helicase unloading, fork collapse, and genome instability |
talk |
|
Desmet, Marsha L |
Interactions between papillomavirus and host during the viral replicative program |
poster |
|
Devbhandari, Sujan |
Intrinsic stability of stalled eukaryotic replication forks |
talk |
|
Donaldson, Anne |
RIF1 protects stalled replication forks from degradation by DNA2 |
talk |
|
Douglas, Max E |
The mechanism of eukaryotic CMG helicase activation |
talk |
|
Dovrat, Daniel |
Live-cell measurement of eukaryotic replication fork progression rates |
poster |
|
Dukaj, Livio |
Regulation of replication timing by the number of MCMs loaded at origins |
poster |
|
Duronio, Robert J. |
Interrogating chromatin regulation of metazoan DNA replication using histone genetics |
talk |
|
Dutta, Anindya |
A histone-chaperone independent function of ASF1a in promoting NHEJ by facilitating MDC1 phosphorylation and histone-ubiquitination at double-strand breaks |
poster |
|
Dwivedi, Gajendradhar |
Trans-lesion DNA polymerases, along with polymerase δ, are required for the increase in mutations associated with double-strand break repair |
poster |
|
Eckert, Kristin |
Replication stress induces DNA polymerase η expression and relocalization to prevent late replication arrest and apoptosis |
poster |
|
El Hage, Aziz |
Ribonucleotide reductase is a limiting factor for ribonucleotide incorporation in genomic DNA during replication |
poster |
|
Enemark, Eric |
Mechanism of DNA translocation and replication initiation by the MCM complex |
talk |
|
Feng, Weiran |
BRCA2 suppresses replication stress-induced mitotic and G1 abnormalities through homologous recombination |
poster |
|
Feng, Wenyi |
Insights from comparative analysis of origin usage via genome-wide ssDNA mapping in two Saccharomyces cerevisiae laboratory strains |
poster |
|
Follonier, Cindy |
Human PIF1 helicase prevents telomere shortening and end-to-end fusion |
poster |
|
Galati, Elena |
Vid22 plays a role in maintaining genome integrity at G-quadruplex loci |
talk |
|
Galletto, Roberto |
Inhibition of the MRX-dependent activation of Tel1 kinase by Rif2 |
poster |
|
Gallo, David |
Rad5 is recruited to stressed DNA replication forks to prevent the accumulation of ssDNA |
poster |
|
Gambus, Aga A |
Cul2Lrr1 ubiquitin ligase drives replisome disassembly at the termination of eukaryotic replication forks |
poster |
|
Garbacz, Marta A |
Evidence that DNA polymerase delta contributes to initiation of leading strand DNA replication in Saccharomyces cerevisiae |
talk |
|
Gastl, Bastian |
Cells harboring mutant KRAS are sensitive to the depletion of replication factor MCM7 |
poster |
|
Gay, Sophie |
Mad2 collaborates with the intra-S checkpoint to coordinate S-phase cyclin expression and promote cell survival in case of replication stress. |
talk |
|
Gelot, Camille |
DDK promotes timely completion of DNA replication by stabilizing stalled replication forks |
poster |
|
Gerbi, Susan |
Influence by ecdysone and transcription on developmentally regulated DNA re-replication in Sciara DNA puffs |
poster |
|
Ghoshal, Kalpana |
The role of Fkh1/2 FHA domain and interacting proteins in the regulation of replication origin timing in S. cerevisiae |
poster |
|
Giannattasio, Michele |
Dissecting the essential roles of S. cerevisiae Dna2 |
poster |
|
Gilbert, David |
Genetic dissection of functional elements in replication timing control |
talk |
|
Gomez, Maria |
Chromatin conformation regulates the coordination between DNA replication and transcription |
talk |
|
Grabarczyk, Daniel B |
Structural basis for the recruitment of Ctf18-RFC to the replication fork |
poster |
|
Gros, Julien N |
Transcription termination at replication origins in S. cerevisiae |
poster |
|
Gutierrez, Monica P |
Establishment of chromatin architecture behind the DNA replication fork |
poster |
|
Hailemariam, Sarem |
Activation of the yeast Tel1ATM checkpoint kinase by the Mre11, Rad50 and Xrs2 (MRX) complex and by DNA |
poster |
|
Hamperl, Stephan J |
Transcription-replication conflict orientation modulates R-loop levels and activates distinct DNA damage responses |
poster |
|
Hanley-Bowdoin, Linda |
Characterization of the Arabidopsis replication timing program and putative origin regions |
poster |
|
Heinz, Kathrin S |
Epigenetic (com)position on DNA replication timing |
talk |
|
Higashi, Torahiko L |
Structural dynamics of the cohesin ring during DNA entry and exit |
poster |
|
Hiratani, Ichiro |
Single-cell DNA replication timing profiling and the 3D genome organization dynamics |
talk |
|
Hizume, Kohji |
CMG helicase activity on chromatinized DNA and at the replication fork barrier |
poster |
|
Hoefer, Verena |
MTBP haploinsufficiency may model replicative stress caused by initiation defects |
poster |
|
Hoggard, Timothy A |
Control of origin licensing in euchromatin by the yeast heterochromatin regulators Sir2 and Sir3 and implications for genome stability |
poster |
|
Hoggard, Timothy A |
The Fkh1 forkhead associated (FHA) phosphothreonine binding domain regulates a mating-type chromosomal transaction and DNA replication origins in budding yeast |
poster |
|
Hossain, Manzar J |
Cyclin-CDK switch promotes the dynamic association of ORC1 to CDC6 and its degradation by SCFskp2 complex in human cells |
poster |
|
Hulke, Michelle L |
Sites of germline mutation show developmental plasticity in DNA replication timing |
poster |
|
Hyrien, Olivier |
Changes in genome-wide replication landscape associated with tumour progression |
talk |
|
Ikui, Amy |
DNA replication control in Chlamydomonas reinhardtii |
poster |
|
Ilves, Ivar |
Keap1—MCM3 interaction coordinates oxidative stress response and genome replication |
poster |
|
Ishibashi, Mai |
DNA replication-coupled acetylation of cohesin complex by Esco2 acetyltransferase in heterochromatic region |
poster |
|
Jackson, Andrew |
Insights from comparative analysis of origin usage via genome-wide ssDNA mapping in two Saccharomyces cerevisiae laboratory strains |
talk |
|
Jeruzalmi, David |
Mechanisms of opening the bacterial replicative helicase by a helicase loader |
talk |
|
Jha, Sudhakar |
TIP60 represses telomerase expression—A HAT with new tricks |
poster |
|
Jia, Weiyan |
Regulated alternative splicing contributes to RIF1 functional diversity |
poster |
|
Jodkowska, Karolina |
Comparative analysis of constitutive and stress-responsive replication origins |
poster |
|
Johansson, Erik |
Structural and functional studies of yeast Pol epsilon |
poster |
|
Johnson, Catherine |
PCNA retained on DNA acts as an obstacle and causes spontaneous DNA damage requiring homologous recombination? |
poster |
|
Jones, Mathew J |
DDK promotes timely completion of DNA replication by stabilizing stalled replication forks |
Talk |
|
Joudeh, Luay |
Dissecting the stimulation of FEN1 activity by PCNA on Flap substrates at the single molecule level |
poster |
|
Kanemaki, Masato T. |
MCM-BP is an MCM chaperon protecting the MCM sub-complexes from degradation |
poster |
|
Kang, Sukhyun |
Human ATAD5 forms dual function complex to turn off PCNA activities |
poster |
|
Kee, Younghoon |
UBR5-OTUD5 interplay regulates transcriptional repression at damaged chromatin |
poster |
|
Kellner, Vanessa |
The Rtt101Mms22 E3 ubiquitin ligase is required for survival of DNA damage caused by misincorporated genomic ribonucleotides and CPT-induced lesions |
poster |
|
Kerem, Batsheva |
Replication fork acceleration is a novel form of replication stress underlying oncogene-induced genomic instability |
talk |
|
Khondker, Shoily P |
Nuclear PP2ACdc55 maintains sister chromatid cohesion in replication stress conditions |
poster |
|
Kilkenny, Mairi L |
Evolutionary changes in replisome architecture—The HMG box of human AND-1 interacts with Pol α – primase |
poster |
|
Kim, Tae Moon |
Functional analysis of human RAD51 variants on genome maintenance |
poster |
|
Koehler, Kerstin |
Cdk8 is a novel MTBP interacting protein required for efficient vertebrate DNA replication |
poster |
|
Koren, Amnon |
Genetic associations of DNA replication timing in 108 human embryonic stem cell lines |
talk |
|
Kose, Hazal B |
Investigating interactions of the eukaryotic replicative helicase with DNA |
poster |
|
Krude, Torsten |
NuRD complex from Xenopus laevis eggs is essential for DNA replication |
talk |
|
Kumagai, Akiko |
The Treslin complex plays a key role in the selection and activation of replication origins |
talk |
|
Kumar, Charanya |
The effect of R-loops on the progression of eukaryotic replication forks in vitro |
poster |
|
Kupiec, Martin |
Roles of the yeast PCNA unloader Elg1 in genome stability maintenance |
poster |
|
Lam, Fred |
A BRD4-TopBP1 interaction regulates activation of the ATR-Chk1 pathway caused by transcription-replication collision events |
talk |
|
Langston, Lance D |
Mcm10 functions to isomerize CMG-DNA for replisome bypass of DNA blocks |
poster |
|
Lanz, Michael C |
Spatial manipulation of Mec1 activation defines separable roles for Mec1/ATR in DNA replication and genome maintenance |
poster |
|
Larasati |
The role and regulation of Rif1 in response to DNA damage |
poster |
|
Li, Huilin |
Fork orientation and origin melting—Insights from cryo-EM |
talk |
|
Li, Joachim J |
Role of structure specific endonucleases in re-replication induced DNA damage |
talk |
|
Li, Qing |
Chaperoning RPA during DNA replication |
poster |
|
Lin, Yea-Lih |
SAMHD1 acts at stalled replication forks to prevent ssDNA-mediated induction of type I interferons |
poster |
|
Lin, Yo-Chuen |
Novel role of Orc6 in DNA damage response |
poster |
|
Liu, Hon Wing |
The role of replication factor C (RFC) complexes in sister chromatid cohesion establishment |
poster |
|
Lopes, Massimo |
Replication fork remodeling—A double-edged sword in genome stability and cancer therapy |
talk |
|
Lu, Wei-Ting |
Drosha drives the formation of R-loops around DNA break sites to facilitate DNA damage repair |
talk |
|
Luna, Lucas |
The role of the fingers domain in the unusual infidelity of DNA polymerase V |
poster |
|
Lygerou, Zoi |
Cdt2 is recruited to damaged chromatin independently of Cdt1 and stabilizes Cdt1 binding |
Poster |
|
Lynch, Kelsey L |
Constraints upon replication initiation factor activity reduce origin efficiency while firing time is maintained |
poster |
|
Mansisidor, Andrés |
Circular DNA provides short-term copy-number amplification of the ribosomal DNA repeats |
poster |
|
Martin, Rebecca M |
Origins of inverted amplicons in S. cerevisiae |
poster |
|
Masai, Hisao |
Claspin/Mrc1 regulates replication initiation and checkpoint by recruiting Cdc7 kinase |
talk |
|
Mason-Osann, Emily O |
The regulation of TERRA R-loops and their role in the alternative lengthening of telomeres |
poster |
|
Masukata, Hisao |
Spatial and temporal control of chromosome DNA replication by telomere-binding proteins |
poster |
|
Mechali, Marcel |
Revisiting the link between replication licensing and mitosis |
poster |
|
Meng, Xiangzhou |
DNA polymerase epsilon uses a unique domain to promote replication initiation and progression |
poster |
|
Menon, Shruti |
A novel tool to study co-transcriptional R-loops formed upon replication stress |
talk |
|
Miller, Jonathan C |
Mitochondrial DNA polymerase IC in Trypanosoma brucei is a multifaceted protein involved in genome replication and positioning |
poster |
|
Miller, Thomas C |
The assembly of replication complexes on chromatin |
poster |
|
Mishra, Bhanvi |
Inhibition of cell proliferation by DNA polymerase δ inhibitor |
poster |
|
Mohni, Kareem N |
RSS1 is an SOS response protein conserved in all domains of life |
poster |
|
Moiseeva, Tatiana N. |
ATR kinase inhibition induces unscheduled replication origin firing through novel Cdc7-dependent interaction between And-1 and the GINS complex |
poster |
|
Mukherjee, Progya P |
In vitro Reconstitution of CMG ubiquitylation by SCFDIA2 |
poster |
|
Muller, Carolin A |
Nanopore sequencing detects nucleotide analogues, allowing single-molecule analysis of DNA replication |
poster |
|
Munden, Alexander L |
Characterization of replication fork composition during development |
poster |
|
Myung, Kyungjae |
SHPRH regulates rRNA transcription by recognizing the histone code in an mTOR-dependent manner |
poster |
|
Naiman, Karel |
Polymerase δ usage after homologous recombination dependent replication fork restart |
poster |
|
Nandi, Saikat |
TOPBP1/Dpb11 facilitates recruitment of the GINS complex to Mcm2-7—An evolutionary conserved mechanism bearing species specificity |
talk |
|
Nassar, Joelle |
Studying the function(s) of Obi1, a novel E3 ubiquitin ligase, in DNA replication using Xenopus egg extracts |
poster |
|
Natsume, Toyoaki |
Acute degradation of the human SMC complexes using the auxin-inducible degron (AID) technology reveals their cell-cycle specific roles in maintaining genome stability |
poster |
|
Nayak, Sumeet U |
FANCJ and its BRCA1 interaction direct replication fork dynamics by regulating Rad51 chromatin accumulation |
poster |
|
Nishiyama, Atsuya |
Uhrf1-dependent two mono-ubiquitylation of histone H3 ensures maintenance DNA methylation |
poster |
|
Noguchi, Eishi |
Maf1, the master regulator of RNA polymerase III, prevents genomic instability at tRNA genes to extend lifespan under calorie-restricted conditions |
poster |
|
Nordman, Jared |
Rif1 inhibits replication fork progression and controls copy number in Drosophila |
talk |
|
Oberdoerffer, Philipp |
Replication stress shapes a protective chromatin environment across fragile genomic regions |
poster |
|
Ohashi, Eiji |
Intramolecular binding of Rad9 C-terminal tail to Rad9-Hus1-Rad1 core ring structure regulates the binding of DNA damage response proteins |
poster |
|
Osmundson, Joseph S |
Okazaki fragment processing, but not ligation, is required for replication fork progression |
poster |
|
Parker, Matthew W |
Cdt1’s DNA-binding activity impinges on multiple regulatory pathways |
poster |
|
Pasero, Philippe |
A novel mechanism linking fork processing to inflammation |
talk |
|
Patel, Darshil R |
The 9-1-1 DNA damage response complex acts upstream of FANCD2 and RAD51 during DNA interstrand crosslink repair |
talk |
|
Paul Solomon Devakumar, Lovely Jael |
Removal of excess PCNA from DNA by the Elg1 complex ensures mismatch repair |
poster |
|
Paulsen, Teressa |
MicroDNA (extrachromosomal circular DNA) in normal tissues and cancers express short regulatory RNAs and can be detected in the cell-free DNA in the circulation |
talk |
|
Peake, Jasmine D |
Roles of the Fanconi anemia DNA repair pathway and acetaldehyde detoxification in preventing genomic instability in esophageal keratinocytes |
poster |
|
Peddu, Chandana |
Regulation of Pol η involvement in DNA replication by phosphorylation and sequestration |
poster |
|
Penengo, Lorenza |
RNF8/RNF168/53BP1 pathway regulates replication fork progression and remodeling |
talk |
|
Pfister, Katherine |
Identification of drivers of Chromosome Instability in Breast Tumors |
Poster |
|
Phizicky, David |
Mechanisms preventing DNA replication between meiosis I and meiosis II |
talk |
|
Pohl, Thomas |
Adaptive telomere shortening in response to environmental stress requires shelterin rearrangement. |
Poster |
|
Pomerantz, Richard T |
How RNA transcripts coordinate DNA recombination and repair |
poster |
|
Porcella, Sarina |
Determining lagging-strand priming dynamics in vivo |
poster |
|
Posse, Viktor |
Initiation of human mitochondrial DNA replication with purified proteins |
talk |
|
Poulet-Benedetti, Jeremy |
Determinants of replication origins in vertebrate cells |
poster |
|
Prasanth, Supriya G |
ORCA/LRWD1 regulates homologous recombination at ALT-telomeres |
poster |
|
Prioleau, Marie-Noelle |
Determinants of replication origins in vertebrate cells |
talk |
|
Prorok, Paulina |
Functional analysis of metazoan DNA replication origins |
poster |
|
Ptasinska, Katie |
Does modulating the efficiency of origin firing dictate global replication timing domains? |
poster |
|
Puddu, Fabio |
Surveying for genes influencing mutation signatures and repetitive DNA stability |
poster |
|
Raghuraman, M. |
A Meier-Gorlin syndrome mutation results in locus-specific chromosome breakage and a ribosome deficiency in yeast |
talk |
|
Ramani, Priya D |
HMGA2 as a key regulator of telomere stability through control of DNA topology |
poster |
|
Reusswig, Karl-Uwe |
Robust replication control by temporal separation of replication phases |
poster |
|
Reynolds-Winczura, Alicja |
An analysis of the interaction between the Ctf18 complex and Pol epsilon in yeast and human cells highlights its role in genome stability |
poster |
|
Rhind, Nick |
Genome-wide single-molecule mapping of human replication kinetics |
talk |
|
Richardson, Chris |
CRISPR-Cas9 genome editing in human cells works via the Fanconi anemia pathway |
poster |
|
Rogers, Cody M |
The Hrq1 helicase stimulates Pso2 nuclease activity to facilitate DNA inter-strand crosslink repair |
poster |
|
Rouse, John |
New mechanisms controlling nuclease recruitment stalled replication forks |
talk |
|
Royrvik, Ellen |
Selfish replication and cell-level selection explain complex tissue-specific patterns of mtDNA segregation |
poster |
|
Saldivar, Joshua C |
ATR ensures completion of DNA replication by regulating transcription of the G2/M network |
talk |
|
Sale, Julian |
Monitoring the replication of structured DNA through the lens of the epigenome |
talk |
|
Sanchez, Humberto |
Single-molecule imaging of loaded yeast Mcm2-7 complex on DNA |
poster |
|
Sansam, Christopher L |
BET proteins promote efficient DNA replication by targeting TICRR/TRESLIN to acetylated chromatin |
talk |
|
Santocanale, Corrado |
DNA replication dynamics and cellular responses to ATP competitive CDC7 kinase inhibitors |
poster |
|
Sau, Soumitra |
A role for the Elg1 RFC-like complex, the main unloader of PCNA, in the DNA damage response |
poster |
|
Schafer, Jonas A |
The nuclear proteins P73 and CUL4A confer resistance to cytarabine by REV3L, the catalytic subunit of translesional DNA polymerase ζ |
poster |
|
Schauer, Grant |
Dynamic functionality of the Mrc1-Tof1-Csm3 fork protection complex with the replisome |
talk |
|
Schildkraut, Carl |
Visualizing DNA replication in telomeres in real time in living cells |
talk |
|
Schlacher, Katharina |
p53 is a keystone replication protein that suppresses BRCA-deficient cancer cell survival restart pathways |
talk |
|
Schwob, Etienne |
Low replication fork density and extended S phase are putative hallmarks of cancer cells |
poster |
|
Schwob, Etienne |
Switch from normal to break-induced replication upon mitotic entry of cells with under-replicated DNA |
poster |
|
Seller, Charles A |
Rif1 prolongs S phase at the mid-blastula transition in the Drosophila embryo |
talk |
|
Shastri, Nishita K |
Defining sites of replication fork collapse due to ATR inhibition |
poster |
|
Sherman, Robin |
Control of mitotic cohesion by RNA and RBMX targeted Aurora-B kinase |
Poster |
|
Shibata, Etsuko |
Three subunits of human ORC are dispensable for DNA replication in cancer cell lines, but the ORC holocomplex is important for establishing repressed chromatin |
Poster |
|
Sidorova, Julia |
Roles of histone deacetylases HDAC1 and HDAC2 at ongoing and stalled replication forks in human cells |
poster |
|
Simon, Itamar |
Mapping replication timing in mouse germ-line cells revealed the centrality of the replication program in shaping genomic composition |
poster |
|
Simoneau, Antoine |
A novel interplay between chromatin structure and telomere length maintenance promotes completion of DNA replication |
poster |
|
Smith, Matt A |
The role of Srs2 helicase in recovery from replication stress |
poster |
|
Smogorzewska, Agata |
Removal of RTFDC1 from stalled replisomes promotes maintenance of genome integrity |
talk |
|
Smolka, Marcus |
Positive and negative control of homologous recombination via TOPBP1 shapes genome stability in S-phase |
talk |
|
Sokka, Miiko |
Mapping origins of DNA replication |
poster |
|
Somyajit, Kumar |
Redox-sensitive regulation of replication fork speed |
talk |
|
Sparks, Justin L |
CMG can bypass a covalent DNA-protein complex |
poster |
|
Speck, Christian |
Structural basis of replicative helicase recruitment by ORC, Cdc6 And Cdt1 |
talk |
|
Spies, Julian |
53BP1 nuclear bodies orchestrate the replication-coupled repair of heritable DNA damage |
poster |
|
Stewart, Jason A |
The human CST complex influences the levels of chromatin-bound MCM2-7 |
poster |
|
Stirling, Peter C |
Quantifying gene-drug interactions by synthetic hypermutation and deep sequencing |
poster |
|
Sutani, Takashi |
In silico prediction of DNA replication origin position in fission yeast genome |
poster |
|
Sybouts, Erin |
Recombination and BLM helicase compensate for replication fork defects in the absence of 53BP1 protein |
poster |
|
Syed, Salahuddin |
Response to increased ribonucleotide incorporation using mass spectrometry |
Poster |
|
Taglialatela, Angelo |
Restoration of replication fork stability and genome integrity in BRCA1- and BRCA2-deficient cells by inactivation of SNF2-family fork remodelers |
Poster |
|
Tahiliani, Mamta V |
Chromosomal rearrangements at hypomethylated satellite sequences are associated with impaired progression of the replication fork and increased fork stalling |
poster |
|
Takahashi, Tatsuro |
A PCNA-dependent reaction facilitates replication-coupled Sororin loading in Xenopus egg extracts |
poster |
|
Tanaka, Seiji |
Interaction between the replication initiation factor Sld3 and the histone acetyltransferase Esa1 promotes the activation of subset of replication origins in budding yeast |
poster |
|
Tang, Erli |
DNA damage, replication stress and cellular senescence stimulate induction of IL-19 |
poster |
|
Taylor, Martin |
The mutational burden of a biased mask |
poster |
|
Taylor, Martin R |
Fate of the eukaryotic replisome upon polymerase stalling |
talk |
|
Terui, Riki |
The Smarcad1/Fun30 chromatin-remodeling enzyme assists a MutSα/MutSβ-dependent step in the eukaryotic mismatch repair reaction |
poster |
|
Tetik, Bilal |
Reconstituting vertebrate pre-IC (pre-initiation complex) formation by combining in vitro biochemistry and Xenopus egg extracts |
poster |
|
Thada, Vaughn A |
Identification of the critical features of the ETAA1 and TopBP1 ATR activation domains |
poster |
|
Tsurimoto, Toshiki |
CTF18-RFC complexed with DNA polymerase ε actively loads PCNA to maintain the efficient DNA synthesis |
talk |
|
Tye, Bik K. |
Open-ringed structure of the Cdt1-MCM2-7 complex as a precursor of the MCM double hexamer |
poster |
|
Uehara, Ryo |
Unequal contribution of two activities of RNase H2 to mouse viability during embryonic development |
poster |
|
Vindigni, Alessandro |
MRE11 and EXO1 nucleases degrade reversed forks and lead to MU81-dependent fork rescue in BRCA2-deficient cells |
talk |
|
Voelker-Albert, Moritz |
The kinetics of chromatin assembly |
poster |
|
Vrtis, Kyle B |
The architecture of collapsed forks—Implications for replication restart |
talk |
|
Waga, Shou |
Further characterization of the binding of human ORC to G-quadruplex-formable single-stranded DNA |
poster |
|
Walter, Johannes |
Single molecule visualization of CMG dynamics during replication in Xenopus egg extracts |
talk |
|
Wang, Hsiang-Tsui |
Acrolein preferentially damages nucleolus eliciting ribosomal stress and apoptosis in human cancer cells |
poster |
|
Wanrooij, Paulina H |
Ribonucleotides misincorporated in yeast mtDNA are not efficiently repaired |
poster |
|
Wear, Emily E |
DNA replication timing programs during development of maize root tips |
poster |
|
Wu, Pei-Yun |
The organization of genome duplication is a critical determinant of the landscape of genome maintenance |
poster |
|
Xia, Yisui |
How is CUL-2LRR-1 recruited to the replisome during DNA replication termination? |
poster |
|
Yardimci, Hasan |
The molecular mechanism of DNA unwinding by the eukaryotic replicative helicase |
talk |
|
Yardimci, Sevim |
Super-resolution fluorescence imaging of DNA replication bubbles |
poster |
|
Yeung, Rani |
Genome-wide analysis of replication-transcription conflicts |
poster |
|
Zegerman, Philip |
Helicase subunit Cdc45 recruits the checkpoint kinase Rad53 to regulate both replication initiation and elongation |
talk |
|
Zhai, Yuanliang |
Unique roles of the non-identical MCM subunits in DNA replication licensing |
poster |
|
Zhang, Haiyang |
Fkh1 regulates sub-nuclear origin localization and replication initiation timing in S. cerevisiae |
poster |
|
Zhang, Zhiguo |
Checkpoint kinase Rad53 couples leading and lagging strand DNA synthesis under replication stress |
poster |
|
Zhao, Xiaolan |
Acute Smc5/6 depletion reveals its role in regulating the Mph1 DNA helicase during programmed replication pausing |
poster |
|
Zhou, Bo |
Characterization of binding interfaces between Geminin and Cdt1 |
poster |
|
Zhou, Zhi-Xiong |
Contributions of major DNA replication fidelity pathways in eukaryotic genome |
poster |
|
Zou, Lee |
A mitosis-specific and R loop-driven ATR pathway promotes faithful chromosome segregation |
talk |