Sean Eddy is a Howard Hughes Medical Institute investigator and the Goldfarb Distinguished Professor of Computational Biology in the Department of Genetics at the Washington University School of Medicine in St. Louis. His research interests are in the development of computational algorithms for genome sequence analysis. He is the author of the HMMER software for biological sequence analysis, a coauthor of the Pfam database of protein domains, and a coauthor of the book Biological Sequence Analysis: Probabilistic Models of Proteins and Nucleic Acids (Cambridge University Press, 1998). Dr. Eddy received his bachelors degree from the California Institute of Technology, his Ph.D. from the University of Colorado at Boulder, and was a postdoctoral fellow at NeXagen Pharmaceuticals and at the MRC Laboratory of Molecular Biology.