PTEN Pathways & Targets
March 16 - 20, 2010
ABSTRACT DEADLINE EXTENDED: January 31, 2010

Organizers:
Suzanne Baker, St. Jude Children's Research Hospital
Lewis Cantley, Beth Israel Deaconess Medical Center
Pier Paolo Pandolfi, Harvard Medical School
Ramon Parsons, Columbia University

Typical Program

We are pleased to announce the third Cold Spring Harbor conference on PTEN Pathways & Targets, which will begin at 7:30 pm on Tuesday, March 16 and run through lunch on Saturday, March 20, 2010.

The 2010 meeting is intended to bring together a diverse group of scientists studying various molecular, genetic and biochemical approaches to the analysis of the PTEN pathway at the cellular level and in development and diseases including cancer, diabetes, and neurological disorders such as autism. Junior and senior researchers will join to discuss their latest research findings and technical approaches toward the analysis of the PTEN pathway. Particular emphasis will be given to model systems, disease pathogenesis and therapy. While a number of speakers have been invited, please note that the majority of oral presentations will be drawn from openly submitted abstracts.

Session Themes:
* PTEN Regulation
* Upstream of PTEN
* Downstream of PTEN (PDK 1/mTORC2/AKT)
* Intersecting Pathways: AMPK/TSC/mTORC1
* Therapeutic Modulation of the Pathway
* Aging, Metabolism and Cancer
* Disease Models

Invited Speakers & Session Chairs:
Domenico Accili, Columbia University College of P&S
Mario Amzel, The Johns Hopkins University
Suzanne Baker, St.Jude Children's Research Hospital
John Blenis, Harvard Medical School
Anne Brunet, Stanford University
Lewis Cantley, Beth Israel Deaconess Medical Center
Karen Cichowski, Brigham and Women's Hospital
Carlos Cordon-Cardo, Columbia University
Peter Devrentes, The Johns Hopkins University
Britta Eickholt, King's College, London UK
Jeff Engelman, Massachusetts General Hospital
Emilio Hirsch, University of Torino, Italy
David Kwiatkowski, Brigham and Women's Hospital
Nick Leslie, University of Dundee, UK
Brendan Manning, Harvard University
Gordon Mills, UT MD Anderson Cancer Center
Alexandra Newton, University of California, San Diego
Pier Paolo Pandolfi, Harvard Medical School
Luis Parada, UT SW Medical Center
Ramon Parsons, Columbia University
Thomas Roberts, Dana-Farber Cancer Institute
Neal Rosen, Memorial Sloan Kettering Cancer Center
David Sabatini, Whitehead Institute for Biomedical Research
Reuben Shaw, Salk Institute for Biological Studies
Lloyd Trotman, Cold Spring Harbor Laboratory
Alex Toker, Beth Israel Deaconess Medical Center
Peter Vogt, The Scripps Research Institute
Hong Wu, University of California, Los Angeles

Abstracts should contain only new and unpublished material and must be submitted electronically by the abstract deadline. Selection of material for oral and poster presentation will be made by the organizers and individual session chairs. Status (talk/poster) of abstracts will be posted on our web site as soon as decisions have been made by the organizers.

We are eager to have as many young people as possible attend since they are likely to benefit most from this meeting. We have applied for funds from government and industry to partially support graduate students and postdocs. Apply in writing to beavers@cshl.edu stating need for financial support - preference is given to those submitting abstracts.

All questions pertaining to registration, fees, housing, meals, transportation, visas, abstract submission or any other matters may be directed to beavers@cshl.edu

We look forward to seeing you at Cold Spring Harbor in March.

This conference is supported in part by funds provided by:
National Cancer Institute

We have funds to provide partial scholarships for individuals who are US citizens/permanent residents from minority groups under-represented in the life sciences. Please provide justification in writing to beavers@cshl.edu and state your financial needs. Preference will be given to those applying who submit abstracts to the meeting.

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Regular packages are all inclusive and cover registration, food, housing, parking, wine-and-cheese party, lobster banquet, etc. No Housing packages include all costs except housing. Full payment is due 4 weeks prior to the meeting.