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C. ELEGANS
August 11 - 26, 2007
Application Deadline: March 15, 2007

Instructors:
Mario De Bono, MRC Laboratory of Molecular Biology, UK
Arshad Desai, University of California San Diego
Shawn Ahmed, University of North Carolina

This course is designed to familiarize investigators with C. elegans as an experimental system, with an emphasis on both classical genetic analysis and reverse genetic approaches. A major goal is to teach students how to successfully exploit the information generated by the C. elegans genome project. The course is suited both for those who have a current training in molecular biology and some knowledge of genetics, but have no experience with C. elegans, as well as students with some prior worm experience who wished to expand their repertoire of expertise. The following topics will be covered both in the laboratory and by lectures from experts in the field: worm pushing, C. elegans databases and worm bioinformatics, anatomy and development, forward genetics, chemical and transposon mutagenesis, generation of transgenic animals, expression pattern analysis, reverse genetics, construction and screening of deletion libraries, and RNA inactivation. The course is designed to impart sufficient training to students in the most important attributes of the C. elegans system to enable students to embark on their own research projects after returning to their home institutions.

Speakers in the 2006 course included:
Raffi Aroian, University of California, San Diego
Kaveh Ashrafi, Washington University School of Medicine
Joe Culotti, Mount Sinai Hospital Research Institute, Canada
Abby Dernburg, Lawrence Berkeley National Laboratory
Lesilee Rose, University of California, Davis
Hitoshi Sawa, RIKEN Center for Developmental Biology, Japan
Tim Schedl, Washington University School of Medicine
Shai Shaham, The Rockefeller University
Frank Slack, Yale University
Rolf Sommer, Max Planck Institute for Developmental Biology, Germany
Mei Zhen, Mount Sinai Hospital, University of Toronto Canada

This course is supported with funds provided by the National Institute of Child Health and Human Development

Cost (including board and lodging): $3,180
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