C.
ELEGANS
August 11 - 26, 2007
Application Deadline: March 15, 2007
Instructors:
Mario
De Bono, MRC Laboratory of Molecular Biology, UK
Arshad
Desai, University of California San Diego
Shawn
Ahmed, University of North Carolina
This
course is designed to familiarize investigators with C.
elegans as an experimental system, with an emphasis
on both classical genetic analysis and reverse genetic approaches.
A major goal is to teach students how to successfully exploit
the information generated by the C. elegans genome
project. The course is suited both for those who have a
current training in molecular biology and some knowledge
of genetics, but have no experience with C. elegans, as
well as students with some prior worm experience who wished
to expand their repertoire of expertise. The following topics
will be covered both in the laboratory and by lectures from
experts in the field: worm pushing, C. elegans
databases and worm bioinformatics, anatomy and development,
forward genetics, chemical and transposon mutagenesis, generation
of transgenic animals, expression pattern analysis, reverse
genetics, construction and screening of deletion libraries,
and RNA inactivation. The course is designed to impart sufficient
training to students in the most important attributes of
the C. elegans system to enable students to embark
on their own research projects after returning to their
home institutions.
Speakers
in the 2006 course included:
Raffi Aroian, University of California,
San Diego
Kaveh Ashrafi, Washington University School of Medicine
Joe Culotti, Mount Sinai Hospital Research Institute, Canada
Abby Dernburg, Lawrence Berkeley National Laboratory
Lesilee Rose, University of California, Davis
Hitoshi Sawa, RIKEN Center for Developmental Biology, Japan
Tim Schedl, Washington University School of Medicine
Shai Shaham, The Rockefeller University
Frank Slack, Yale University
Rolf Sommer, Max Planck Institute for Developmental Biology,
Germany
Mei Zhen, Mount Sinai Hospital, University of Toronto Canada
This
course is supported with funds provided by the National
Institute of Child Health and Human Development
Cost
(including board and lodging): $3,180
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