MOLECULAR
NEUROLOGY & NEUROPATHOLOGY
June 6 - 12, 2007
Application Deadline: March 15, 2007
Instructors:
Mark Cookson, National Institute on Aging/NIH
John
Hardy, National Institutes of Health
Harry
Orr, University of Minnesota
This
intensive one-week discussion course offers successful applicants
a unique opportunity to learn the latest concepts and methodologies
associated with the study of human neurological disorders
such as Alzheimer’s, Parkinson’s and epilepsy.
Participants will discuss in detail the strengths and weaknesses
of the accumulated experimental evidence underlying our
current understanding of these diseases. Fundamental questions
- such as how and why particular neurons die in certain
disorders - will be discussed in the context of identifying
the best experimental approaches to finding answers, whether
through the use of transgenic and/or lesion-induced mouse
models, functional brain and/or cellular imaging, gain/loss-of
function molecular and viral approaches, cellular transplantation,
or a combination of these approaches. The course will examine
why many of these disorders share apparently common features
protein aggregation, specific vulnerability of certain classes
of neuron, long incubation period and will discuss to what
extent these features reflect common pathological mechanisms.
The course will further explore how the underlying mechanisms
in these disparate disorders may be targeted for potential
diagnostic and therapeutic gain. Extended seminars and discussion
by a wide range of leading investigators will further illuminate
developments in this rapidly moving field. Participation
in the course will provide an essential conceptual and methodological
framework for anyone intending to pursue rigorous research.
The
course will be held at the Laboratory’s Banbury Conference
Center located on the north shore of Long Island. All participants
stay within walking distance of the Center, close to tennis
court, pool and private beach.
Details
including seminar speakers from the 2006 partner course
in the UK
This
course is supported with funds provided by the Howard
Hughes Medical Institute.
