ADVANCED BACTERIAL GENETICS
June 6 - 26, 2007
Application Deadline: March 15, 2007

Instructors:
John Kirby, University of Iowa
Susan Lovett, Brandeis University
Anca Segall, San Diego State University

The course will present logic and methods used in the genetic dissection of complex biological processes in eubacteria. Laboratory methods to be used include: classical mutagenesis using transposons, mutator strains, and chemical and physical mutagens; the mapping of mutations using genetic and physical techniques; modern approaches to the generation and analysis of targeted gene disruptions and fusions using PCR and cloning methods; epitope insertion mutagenesis; and, site-directed mutagenesis. Key components of the course will be the use of sophisticated genetic methods in the analysis of model eubacteria, and the use of the wealth of new genomic sequence information to motivate these methods. Invited lecturers will present various genetic approaches to study eubacterial mechanisms of metabolism, development, and pathogenesis.

Speakers in the 2006 course included:
Susan Golden, Texas A & M University
E. Peter Greenberg, University of Washington
Ann Hochschild, Harvard Medical School
William Jacobs, Albert Einstein College of Medicine/HHMI
Christine Jacobs-Wagner, Yale University
Igor Jouline, University of Tennessee-Oak Ridge Nat'l Lab.
Roberto Kolter, Harvard Medical School
Stanley Maloy, San Diego State University
Forest Rohwer, San Diego State University
John Roth, University of California, Davis
Abigail Salyers, University of Illinois at Urbana-Champaign

This course is supported with funds provided by the National Science Foundation.