SYSTEMS BIOLOGY:
GLOBAL REGULATION OF GENE EXPRESSION

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Abstracts are listed alphabetically by presenting author.

Presenting Author

Abstract Title

Talk/Poster

Aburatani, H.

Epigenetic profiling in cellular differentiation

poster

Aerts, S.

Practical identification of regulatory interactions in Drosophila transcriptional networks

poster

Akavia, U.

Conexic—Combining copy number and gene expression to uncover dysregulation in melanoma

poster

Alleyne, T.

Predicting the binding preference of transcription factors to individual DNA k-mers

poster

Amit, I.-.

The architecture of growth factor signaling

poster

Arda, E.

An intricate network of nuclear hormone receptors regulates fat and fasting in the nematode C. elegans

poster

Bejerano, G.

Dispensability of mammalian DNA

poster

Belostotsky, D.

Genome-wide high-resolution mapping of exosome substrates reveals hidden features in the Arabidopsis transcriptome

talk

Ben-Ari, G.

Signal specificity in the mating and invasive growth transcriptional programs in S. cerevisiae is achieved through differential regulation of the Dig proteins

poster

Benfey, P.N.

Getting to the root of cell identity

talk

Bengani, H.

Mining the human genome for components of cellular memory modules

poster

Bernstein, B.E.

Chromatin landscapes of pluripotent and lineage-committed cells

talk

Bhatia, S.

Peptide identity search for identification of trans-acting chromatin remodeling factors in the human genome—Characterization and functional analysis

poster

Blanchette, M.

Genome-wide analysis of alternative pre-mRNA splicing and RNA binding of specificities of the Drosophila hnRNP A/B family members

talk

Bolotin, E.l.

High throughput approach for determination of HNF4a binding motifs

poster

Boorsma, A.

Inferring condition-specific modulation of transcription factor activity through regulon-based analysis of genome wide expression in yeast and human

talk

Bourque, G.

The Hitchhiker's Guide to mammalian transcription factors binding sites

talk

Bristow, C.A.

Boolean construction and representation of spatial patterns in developing tissues

poster

Burge, C.

Global patterns in tissue-specific RNA processing inferred from deep transcriptome sequencing

talk

Butland, S.L.

The transcription factor encyclopedia, Tfe

poster

Calarco, J.A.

Identification and characterization of nSR100, a novel neuronal splicing regulator

poster

Celniker, S.E.

Comprehensive characterization of the Drosophila transcriptome

talk

Cerase, A.

Defining Xist RNA binding sites

poster

Chan, E.T.

MORE—A new regression-based motif model evaluation technique

poster

Chen, B.

Dissecting the complexity of yeast growth

poster

Cheng, D.

An alignment independent algorithm for motif discovery using sequence conservation

poster

Cheng, Y.

Large scale identification of sites bound in vivo by GATA-1 on mouse chromosome 7 reveals major determinants of occupancy

poster

Chu, D.

Metabolic control of the sialic acid metabolism in E. coli

poster

Chu, J.

Computational and molecular characterization of RFX transcription factor mediated transcription

poster

Coulombe, B.

High-precision mapping of the protein interaction network for the human transcription machinery reveals a novel class of cellular regulatory factors

talk

Cui, H.

Genome wide target location analysis reveals a broader role of Shortroot in root development

poster

Degenhardt, T.

Defining novel roles for nuclear receptors

poster

Dekker, J.

Comprehensive 5C maps of chromsomal domains reveal extensive communication between genomic elements

talk

Dequeant, M.

Comparison of the segmentation clock networks in fish, chick and mouse

poster

Dimitrova, N.

In silico prediction of histone methylation regions in DNA sequences

poster

Dudley, A.M.

Systems genetics and posttranscriptional regulation

talk

Ernst, J.M.

A semi-supervised method for predicting transcription factor-gene interactions in E. coli

poster

Fang, N.

Expression profiling of miRNA and mRNA by real-time PCR

poster

Fernando, H.

Targeting a specific promoter g-quadruplex with a single-chain antibody

poster

Friedman, N.

Modularity in genetic interaction networks

talk

Fuite, J.J.

Understanding chronic fatigue using comparative cross-scale analysis of information networks

poster

Garmendia-Torres, C.

P-body dynamics in yeast—A systems biology approach

poster

Gerard, M.

Identification of the regulatory networks controlled by chromatin remodeling factors in mouse embryonic stem cells

poster

Gertz, J.

Analysis of combinatorial cis-regulation in synthetic promoters with weak transcription factor binding sites

talk

Giaever, G.N.

A chemical portrait of the yeast S. cerevisiae—Understanding gene function and drug action

talk

Goff, L.A.

Computationally-predicted regulation of microRNAs via the PDGF pathway during osteogenic differentiation of human MSCs

poster

Goyal, S.

A quantitative comparison of RNA-based and protein-based gene regulation

poster

Grove, C.A.

An integrated C. elegans bHLH dimerization, expression and DNA binding specifity network

talk

Habib, N.M.

A novel Bayesian method for DNA motif comparison elucidates condition-specific DNA binding mechanisms

poster

Hanlon, S.

Promoter architecture dynamically modulates transcription factor binding and transcriptional output over time

poster

Hawkins, D.

Dynamics of the human embryonic stem cell epigenome reveal key cis-regulatory elements

poster

Hawrylycz, M.J.

Co-expression networks in the C57BI/6J mouse brain

talk

Hon, G.

A genome-wide map of human transcriptional enhancers

talk

Hughes, T.

Complexity and diversity in the protein-DNA interactome

talk

Ideker, T.G.

Mapping gene regulatory pathways by assembly of physical and genetic interactions

talk

Iniguez, L.

A flexible, high-density array platform for genome-wide characterization of epigenetic and transcriptional regulatory mechanisms involved in cancer

poster

Jaimovich, A.

Automatically inferring a system level functional view from genetic interaction networks

poster

Jim, H.

Identification of target genes of an erythroid transcription factor complex containing SCL (TAL1)

poster

Kainth, P.S.

A genomic approach to map cell cycle transcription pathways in S. cerevisiae

talk

Kaluarachchi, S.

Dual regulation by pairs of cyclin-dependent protein kinases and histone deacetylases control G1 transcription in budding yeast

poster

Kertesz, M.

Roles of RNA structural properties in microRNA regulation

poster

Kheradpour, P.

Identification and evaluation of mammalian regulatory motifs using comparative genomics across 19 mammals

talk

Kingston, R.E.

Identification of proteins bound to a genomic locus

talk

Kinney, J.B.

Mutual information maximization—A universal principle for DNA sequence analysis in the large N limit

poster

Komorowski, J.

A novel algorithm and ChIP-analysis identifies candidate functional SNPs

poster

Kosucu, H.

Discovering hairpin RNA motifs using generative models

poster

Krishnakumar, R.

Genomic analysis of gene regulation by poly(ADP-ribose) polymerase-1

talk

Lagha, M.

Pax3 regulation of FGF signaling affects the progression of embryonic progenitor cells into the myogenic program

poster

Lahesmaa, R.

Novel insights into the gene regulatory networks regulating human T helper (Th) cell differentiation

poster

Laurent, L.

Alterations in gene expression corresponding to recurrent genetic variations observed in human embryonic stem cell cultures

poster

Lee, K.

Multiple approaches for discovery of transcriptional regulation targets of RNT-1 in C. elegans

poster

Li, H.

Dynamics and design principles of a basic regulatory architecture controlling metabolic pathways

talk

Li, X.

Computational identification of protein binding elements in 3'UTRs of mRNAs

poster

Litvin, O.

Golph—Identifying multi-locus iQTLs

poster

Liu, X.

Analysis of ChIP-Seq data elucidates genome-wide human epigenetic regulation at the nucleosome level

talk

Loring, J.F.

Essential pluripotence—Identification of common core networks defining pluripotent cells

talk

Lu, X.

MatrixREDUCE—A software package for biophysical modeling of transcriptional networks

poster

Mann, I.

DNA-binding sequence specifities of AT-Rich interaction domains

poster

Margaritis, A.

Gene-specific dye bias correction for two-color microarrays

poster

Martinez, N.J.

An integrated genome-scale C. elegans miRNA-TF network

talk

Mirny, L.

Nucleosome-mediated cooperatively of transcription factors

poster

Montavon, T.

Long-range enhancer-promoter interactions in the HoxD complex

poster

Morris, Q.D.

The evolution of gene expression in vertebrates

poster

Mortazavi, A.

RNAseq—Ultra-high-throughput sequencing of the transcriptome

poster

Mousavi, K.

Role of the polycomb protein, Ezh1, in terminal differentiation

poster

Mueller, J.

HIF-dependent transcriptional networks—A genome wide location analysis

poster

Murray, J.I.

Imaging C. elegans developmental expression

poster

Mustroph, A.

The analysis of organ and cell-type specific mRNA populations of A. thaliana exposes a global and cell specific response to hypoxia

poster

Nakazato, T.

Functional analysis of groups of genes with MeSH hierarchy

poster

Neto, A.M.

Role of Odd-skipped family genes in the pronephros specification

poster

Nielsen, F.G.

Signal-to-noise optimized oligonucleotide array design

poster

Noyes, M.B.

A comprehensive catalog of homeodomain DNA-binding specificities from D. melanogaster

poster

Odom, D..

Determinants of tissue-specific transcriptional regulation in a mouse-human hybrid mouse

talk

Park, J.

Analysis of microRNA and transcription factor regulatory modules in myogenesis, cardiogenesis, and cardiac hypertrophy

poster

Penalva, L.O.

A multi-step approach to dissect the gene network regulated by Musashi1 and its link to tumorigenesis

poster

Penalva, L.O.

Over-represented sequences located on UTRs are potentially involved in regulatory functions

poster

Peng, W.

Statistical analysis of ChIP-Seq data

poster

Perez, J.C.

Functional evolution of the PhoP transcriptional network in enteric bacteria

poster

Popescu, S.C.

MAPK signaling networks in A. thaliana

poster

Rach, E.

Alternative transcription start sites—Core promoter motifs and distinct spatiotemporal utilization

poster

Radonjic, M.

Genome-wide mRNA expression analysis of high-fat induced hepatic pathophysiology in ApoE3*L mice

poster

Raveh-Sadka, T.

From sequence to expression in Drosophila segmentation—Model and analysis

poster

Ray, D.

A new microarray-based system for the rapid identification of RNA sequence and structure preferences of RNA binding proteins

talk

RIBES, V.C.

Modulation of gene-regulatory network in the neural tube by the morphogene Sonic Hedgehog

poster

Ronaghi, M.

A new search paradigm for large-scale biological data

poster

Rosenfeld, J.A.

Distinct histone modifications are enriched in non-genic and silent regions of the human genome

poster

Rossetti, S.

Retinoic acid receptor a ---A node connecting major tumor suppressor pathways

poster

Rynditch, A.V.

Regulation of functional diversity of adaptor proteins—Family of intersectins

poster

Sandberg, R.

Widespread evasion of posttranscriptional regulation associated with proliferation

poster

Sarkar, S.

HDAC inhibitors reduce CpG methylation in DNA and induce re-expression of genes silenced by methylation in prostate cancer cells

poster

Schroeder, M.

How to make stripes—Deciphering the transition from aperiodic to periodic patterns in Drosophila segmentation

poster

Shannon, M.

Epigenetic control of inducible gene expression in immune cells

poster

Sharov, A.A.

Pou5f1, Sox2, and Nanog directly activate promoters of downstream targets whereas suppression effect is indirect

poster

Shay, T..

DNA—The quantity is not all that counts

poster

SHIN, S.

A novel gonad-specific gene DD2-2 involved in early zygotic gene activation (ZGA) in mouse preimplantation embryos

poster

shukla, j.n.

Isolation and characterization of sex-specific transcripts of doublesex gene from wild silkmoth, A. assama

poster

Simon, I.

A genome-wide transcriptional analysis of the human cell cycle identifies genes differentially regulated in normal and cancer cells

poster

Sinha, S.

Evolutionary analysis of cis-regulatory modules in Drosophila

poster

Sinha, S.

Predicting cis-regulatory modules without motif knowledge

poster

Smirnova, A.S.

Overexpression of KBTBD9 intronic transcripts affects global gene expression profile and proliferation rate of human cells

poster

Som, I.

Developmental stage regulation of the murine b -globin locus

poster

Stamatoyannopoulos, J.A.

Multi-lineage programming of human regulatory DNA

talk

Stansberg, C.

Gene expression in the rat brain—High similarity but unique differences between frontal, temporal and occipital cortex

poster

Stark, A.

Functionality of microRNA star arms and anti-sense microRNAs in Drosophila

talk

sun, X.

Automatic inference of biological networks governing cell differentiation

poster

Tan, W.

Expression of aquaporins in the salt glands of a mangrove species A. officinalis

poster

Tarcic, G.

From input to output—EGF induced cellular program in mammary cell migration

poster

Tillo, D.

High-resolution atlases of nucleosome occupancy and transcription—Mutants and small molecules

talk

Tokoro, M.

Proteome analysis of mouse preimplantation embryos

poster

Troyanskaya, O.

Computationally driven experimental discovery of novel mitochondrial biology

talk

Tsutsumi, S.

A global map of p53-binding sites in the human genome

poster

van Bakel, H.

Comparative transcriptomics in mammals

poster

Van Steensel, B.

Mapping of genome-nuclear lamina interactions reveals domain structure of human chromosomes

talk

Wan, Y.Y.

The histone variant H2A.Z is required for fatty acid induction and peroxisome biogenesis

poster

Wang, J.

Quantitative model for inferring dynamic regulation of the tumor suppressor gene p53

poster

Wang, T.

Species-specific mobile elements shape transcriptional regulatory networks

talk

Wang, W.

Prediction of promoters and enhancers using chromatin modification patterns

poster

Wei, G.

Genome-wide characterization of ETS transcription factor binding specificities and target genes

talk

White, M.

Discovering novel transcriptional regulators of the yeast cell cycle

poster

Whittle, C.M.

The genomic distribution and function of histone variant H2A.Z during C. elegans development

talk

Wickens, M.

Regulation of mRNAs—PUFs, Paps, and poly(A)

talk

Wold, B.J.

Transcriptome input and output—Combined RNASeq and ChIPSeq studies

talk

Wolfe, S.

A systematic characterization of Drosophila transcription factors via a bacterial one-hybrid system

talk

Wu, J.

Transcriptional regulation underlying the mouse EML hematopoietic precursor cell self-renewal and differentiation

poster

Wunderlich, Z.

Information theoretic analysis of binding motifs and combinatorial regulation

poster

Xie, X.

Single molecule approach to molecular biology in living bacterial cells

talk

Yao, J.

Shrinkage error model for cluster analysis of genome-wide expression data

poster

Yu, J.

Molecular cross-talk of androgen receptor and TMPRSS2:ERG fusion in prostate cancer

poster

Zhang, C..

An RNA landscape of evolution for optimal exon and intron discrimination

poster

Zhang, M.

A tale of hunting down after Pumilio

talk

Zheng, J.

Meta-analysis to identify gene regulatory network in metastatic cancer

poster

Zheng, J.

Quantitative genetic interaction mapping reveals the functional organization of transcriptional networks

talk

Zheng, Y.

The identification of HOX11 target genes and their transcription networks

poster

Zhu, Q.

Complex organizational structure of the genome revealed by genome-wide analysis of single and alternative promoters in D. melanogaster

poster

 

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