THE CELL CYCLE

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Abstracts are listed alphabetically by presenting author.

Presenting Author

Abstract Title

Talk/Poster

Abbas, T.A.

PCNA-dependent ubiquitylation and degradation of p21 by the Cul4-Ddbl11 ubiquitin ligase complex in UV-irradiated cells

talk

Abella Marti, N.

DNA damage induces nucleolar p21 localization and inhibits its nuclear export

poster

Adams, P.D.

Epigenetic regulation of cell cycle exit—A likely contributor to tumor suppression and tissue aging

poster

Aggarwal, P.

Phosphorylation of MCM4 at Ser 112 regulates its incorporation into MCM2-7 complex

poster

ALEXANDAR, I.

Characterization of three different suppressors of mutations in the nud1 gene of yeast S. cerevisiae

poster

Alvarez Fernandez, M.

Activation of FoxM1 during G2 requires cyclinA/cdk-dependent relief of auto-repression by the FoxM1 N-terminal domain

poster

Andrulis, E.D.

Malfunctioning Dis3 elicits premature spindle assembly

poster

Araki, H.

CDK-dependent initiation of chromosomal DNA replication in budding yeast

talk

Archambault, V.

Sequestration of Polo kinase to microtubules by phosphopriming-independent binding to Map205 is relieved by Cdk1 at mitotic entry

talk

Asano, M.

The ORC is dispensable for endoreplication in Drosophila

talk

Ayad, N.

Activation domain dependent degradation of somatic wee1 kinase

poster

Bachewich, C.

Regulation of the G1/S transition and differentiation in C. albicans

poster

Bagheri-Yarmand, R.

Overexpression of low molecular weight cyclin e results in fast phase progression via Cdc25E interaction leading to chromosome missegragation in breast cancer cells

poster

Bailly, E.A.

Cell cycle control of the DNA damage response in budding yeast—B-type cyclins matter

poster

Balasov, M.L.

Functional analysis of ORC6 mutant in Drosophila

poster

Balasubramanian, M.K.

Nuc2p, a subunit of the anaphase promoting complex, inhibits separation initiation network following cytokinesis in fission yeast

poster

Balestrini, A.

GCC1, a novel Cdc45 and TopBP1 binding protein required for initiation of chromosomal DNA replication

poster

Bando, M.

Cohesin regulates gene expression in human

poster

Bandura, J.L.

Identification of new regulators of cell cycle exit

poster

Barisic, M.

CCDC99 is essential for mitosis in human cells

poster

Bassermann, F.C.

The Cdc14B-Cdh1-Plk1 axis in the control of the G2 DNA damage response checkpoint

talk

Benanti, J.A.

A proteomic screen for ubiquitin ligase targets uncovers regulation of the kinesin-associated protein Cik1 by APCCDH1

poster

Bengoechea-Alonso, M.

Cdk1 and Plk1 regulate the transcription factor SREBP1 during mitosis

poster

Bianco, J.

Role of the Mrc1/Claspin complex in the maintenance of genome integrity during DNA replication

poster

Biedermann, B.

The C. elegans GLD-1/quaking represses the translation of cyclin mRNAs during meiotic prophase

talk

Biggins, S.

The purification of yeast kinetochores identifies a protein phosphatase 1 regulatory subunit

talk

Blank, H.M.

An increase in mitochondrial DNA promotes nuclear DNA replication in yeast

poster

Bouchoux, C.

Temporal ordering of mitotic exit in budding yeast

poster

Boutros, R.

Cdc25B involvement in centrosome duplication and microtubule nucleation

poster

Brandeis, M.

Study of Cdh1 loss and gain of function

poster

Braschi, E.

Mitochondrial deSUMOylation is a novel cell cycle check point

poster

Buttitta, L.A.

Developmental control of cell cycle exit in Drosophila

poster

Cacalano, N.A.

SOCS3 regulates p21 expression and cell cycle arrest in response to DNA damage

poster

Califano, A.

Comparative molecular interaction analysis reveals physical interactions among proteins regulating initiation of replication and mitosis and their shared transcriptional regulation

poster

Calvi, B.R.

Endo and mitotic cell cycles have distinct re-replication stress responses

talk

Campaner, S.

Cdk2 protects from Myc induced cellular senescence

talk

Campbell, J.L.

Mrc1—A possible coordinator at replication forks

talk

Carlomagno, F.

Protein NCOA4 inhibits eukaryotic DNA replication

poster

Carr, S.M.

Crosstalk between phosphorylation and methylation in the control of retinoblastoma protein

talk

Cerqueira, A.

DNA damage response in the absence of interphase Cdks

poster

Cetin, B.

Is protein phosphatase 2A required for protection of cohesin from separase?

poster

Chauhan, S.

Regulation of Cdc20 during cell cycle

poster

Chen, J.J.

The HPV E6 and E7 oncogenes abrogate the postmitotic and re-replication checkpoints to induce genomic instability

poster

Chibazakura, T.

Cyclin A promotes S-phase entry via interaction with the replication licensing factor Mcm7

talk

Choi, S.

Regulation of the Pcs1-Mde4 monopolin complex by the Cdc14-like phosphatase Clp1 in fission yeast

talk

Chow, C.

Cdc20-dependent degradation of RASSF1A during mitosis

poster

Chu, Z.

Rep2 is stabilized by the S-phase checkpoint that inhibits APC/C at S-phase arrest in S. pombe

poster

Civril, F.

NAG is a novel ZW10 interactor

poster

Clijsters, L.

Regulation of binding and activation of the APC/C by Cdh1

poster

Cobrinik, D.

Retinoblastoma has properties of a cone precursor tumor and depends upon cone cell-specific Mdm2 signaling

poster

Coller, H.A.

let-7 overexpression to G2/M arrest via direct downregulation of Cdc34 and stabilization of Wee1 kinase in primary fibroblasts

talk

Cortez, D.K.

A functional genomic screen identifies novel genes with roles in the maintenance of genome integrity

talk

Cremona, C.

Loss of cell anchorage promotes genomic instability

poster

Cuvier, O.

A topoisomerase II-dependent mechanism for resetting replicons at the S-M phase transition

talk

Cuvier, O.

BEAF dual-cores control cell-cycle chromosome dynamics via epigenetic regulations

poster

DaSilva, T.

Cdk2 threonine 39 phosphorylation by PKB and its effect on cyclin binding and cell cycle progression

poster

Davis, M.A.

Dual degrons regulate cyclin E degradation by the Fbw7 pathway

poster

Dayani, Y.

How yeast resumes the cell cycle upon return to growth from meiosis

poster

De Bruin, R.A.

The DNA replication checkpoint kinases regulate G1/S transcription in response to DNA replication stress

poster

de Olano, N.

The role of MAKAP-K2 in G2/M transition and apoptosis

poster

De Souza, C.P.

Cyclic regulation of the spindle assembly checkpoint independent of microtubule attachments

talk

Deibler, R.W.

Reconstitution of somatic cell mitotic entry as a cell-free system

poster

Denicourt, C.

Analysis of a new family of cyclins involved in G1 to S phase regulation

poster

DePamphilis, M.L.

Nuclear localization and phosphorylation of human Orc6 are required for cytokinesis

poster

DeRan, M.

NPAT coordinates histone gene activation by recruiting the TRRAP-Tip60 complex to histone gene promoters during the G1/S transition

poster

Dick, F.A.

The retinoblastoma protein uses LSCXE type interactions for a stress responsive G1 arrest

talk

Diehl, J.

Phosphorylation-dependent dimerization of the SCFFBX4 ligase is disrupted in human cancer thereby contributing to cyclin D1 overexpression

talk

Dimco, G.X.

Activated STAT1 is involved in cell cycle regulation

poster

Dinarina, A.

Role of chromatin quantity and geometry in spindle formation and organization

poster

Dissmeyer, N.

Functional analysis of plant Cdks

poster

Dotiwala, F.J.

Role of vesicular transport in DNA damage checkpoint

poster

Duronio, B.J.

PIP box-dependent destruction of Drosophila E2F1 during S phase requires CUL4CDT2 and is necessary for endocycle progression

talk

Elowe, S.

Coordinated phosphoregulation of BubR1 by Cdk1 and Plk1 regulates mitotic progression and the stability of kinetochore-microtubule interactions

poster

Enos, M.

Role of Cdk6 in proliferation, differentiation and tumorigenesis

poster

Ericsson, J.

Phosphorylation and degradation of the sREBP family of transcription factors during the cell cycle

talk

Errico, A.

Tipin is required for the stability of replication forks and the DNA replication checkpoint in S. laevis eggs extract

poster

Feng, W.

Untimely centromere duplication and defective replication resumption differentially contribute to death of S. cerevisiae replication checkpoint mutants in hydroxyurea

poster

Francis, L.I.

The S-phase kinase, DDK, specifically targets replication origin-bound MCM complexes

talk

Frolov, M.V.

The role of a dead-box helicase belle in cell proliferation and development

poster

Futcher, B.

Identification of the RNAs bound by the RNA-binding protein WHI3

poster

Futcher, B.

Induction of DNA repair genes in G1 phase

poster

Futcher, B.

Slowly growing cells, stored carbohydrate, and the critical size for Start

poster

Futcher, B.

The yeast G1 cyclin Cln3 binds the CLN2 promoter, and regulates it via histone deacetylase

talk

Garcia-Cortes, J.C.

Fission yeast Edt1 promotes SIN activation through regulation of Spg1

poster

Ge, W.

Pxl1, a paxillin-related protein, stabilizes the actomyosin ring during cytokinesis in fission yeast

poster

Gomez-Hierro, A.

Regulation of the G2/M transition by Ssp1 and Srk1 kinases

poster

Gong, D.

Regulation of mitotic chromatin condensation by cyclin A2 and cyclin B1

poster

Goto, G.H.

Bub1-mediated adaptation of the spindle checkpoint in anaphase

talk

Gould, K.L.

Split decisions—Molecular mechanisms governing contractile ring formation and function

talk

Grieco, D.

An aurora B kinase-Wee1 pathway controls cyclin-dependent kinase 1 activity for timely anaphase onset

poster

Grossel, M.J.

Investigating the mechanism of cdk6 in differentiation

poster

Gutierrez, G.J.

Cell cycle is regulated by activation and degradation of c-Jun N-terminal kinase

talk

Haley, E.

A new role for autophagy in cellular quiescence

poster

Harper, W.

Systematic proteomic analysis of human deubiquitinating domain containing proteins reveals candidate targets and pathways for ubiquitin control

talk

Herr, A.K.

A novel link between ORC5 and dE2F1 dependent transcription

poster

Higgins, J.M.

Aurora B regulates Haspin activity and centromeric histone H3 Thr-3 phosphorylation in mitosis

talk

Hitomi, M.

ATR and ATM induced destabilizing phosphorylation of cyclin D1 on Thr286

poster

Hizli, A.A.

Identification of novel CDK2 substrates functioning in diverse cellular processes

poster

Hoffmann, I.

Plk2 regulates centriole duplication by stabilizing cyclin E

poster

Homma, M.K.

CK2 changes its cellular localization during the progression of cell cycle

poster

Hong, K.U.

Mechanisms of mitosis-specific phosphorylation of TMAP/CKAP2

poster

Huijbregts, R.

The role of Orc6 in regulation of septin function in Drosophila

poster

Hydbring, P.

Cyclin E/Cdk2 functions as a Myc cofactor and regulates Myc stability by phosphorylating serine 62

talk

Ibarra, A.

Excess Mcm proteins protect human cells from replicative stress by licensing backup regulation origins of replication

poster

Illert, A.

Targeted inactivation of nuclear interaction partner of ALK (NIPA) disrupts meiotic prophase

poster

Ishikawa, Y.

Differential specificity of substrate accumulation in ubiquitin ligase SCFFBXW7 deficient fibroblasts and keratinocytes

poster

Jallepalli, P.V.

Separase-mediated proteolysis is essential for telophase-specific dissolution of centriole engagements in human cells

talk

James, M.

Tyrosine phosphorylation of p27/Kip1 affects its ability to inhibit cyclin D-Cdk4

poster

Joukov, V.V.

Analysis of BRCA1 function in the mitotic spindle assembly

talk

Kaldis, P.

Network like regulation of the G1/S transition by Rb, Cdk2, Cdk4, and p27

poster

Kamijo, K.

Determining the furrow-inducing microtubules by Aurora B in cells with a monopolar spindle

poster

Kang, J.

Structure and substrate recruitment of the human spindle checkpoint kinase Bub1

talk

Katzaroff, A.J.

Identification of new genes regulating cell cycle exit

poster

Kilfoil, M.L.

Single cell fast spindle dynamics probed by automated phenotyping

poster

Kim, S.

Phosphorylation-dependent interaction of embryonic Xenopus Wee1A with Cdk1-cyclin B1 complex

poster

Kimata, Y.

Stimulation of the APC/C activity by the Fizzy/Cdc20 family of the activators independent of substrate recruitment

poster

Kimble, J.E.

Cell cycle controls in the C. elegans germ line

talk

King, R.W.

Identification of a small molecule inhibitor of the anaphase-promoting complex

talk

Kipreos, E.T.

The regulation of the Cdc6 DNA replication licensing factor in S phase

talk

Klebig, C.

Bub1 mutants showing separation of function—Spindle checkpoint and kinetochore-microtubule attachment

talk

Knutsen, J.H.

A possible link between cell growth and the cell cycle eIF2a phosphorylation

poster

Kopanja, D.

Proliferation defects and genome instability in cells lacking Cul4A

poster

kops, G.

Chromosomal instability due to a weakened mitotic checkpoint by inefficient Mps1 auto-activation

poster

Kornbluth, S.

Aven-dependent activation of ATM following DNA damage

talk

Korzelius, J.P.

Regulation of proliferation versus differentiation in C. elegans

poster

Kuo, M.

Pericentric chromatin plays a vital role in tension sensing through Sgo1p

poster

Kuroda, T.S.

Understanding the physiological alterations associated with tetraploidy—Potential strategy for novel cancer therapeutics

poster

Kuvichkin, V.V.

Lipid-DNA interactions as the basis of the genome organization

poster

Kwon, M.

Mechanisms to suppress multipolar divisions in cancer cells with extra centrosomes

talk

Labib, K.P.

Ctf4 couples MCM helicase to DNA polymerase a at eukaryotic DNA replication forks

talk

Lacefield, S.

Formation of a synthetic kinetochore in S. cerevisiae by tethering a member of a microtubule binding complex to DNA

talk

Lammens, T.

Atypical E2F restrains APC/C function obligaotry to endocycle onset

talk

Larimore, E.

Effects of Fbw7 dimerization on endogenous substrates

poster

Lavoie, B.D.

Putting the brake on fear—TOF2 is required for the biphasic release of the Cdc14 phosphatase during the mitotic exit

poster

Leatherwood, J.K.

Checkpoint effects and telomere amplification during DNA re-replication in fission yeast

poster

Lee, K.S.

Structural and functional analyses of a minimal phosphopeptide targeting the Polo-box domain of mammalian Polo-like kinase 1

poster

Lee, S.

Skp2 suppresses p53-dependent apoptosis by inhibiting p300

poster

Lee, S.

Tpr is required for the Mad1-Mad2-dependent mitotic spindle checkpoint

poster

Lens, S.M.

Restriction of Aurora-B activity upon bi-orientation promotes timely anaphase onset

talk

Li, C.

A new regulatory element in human Wee1 mediating its inactivation by cyclin A/Cdk2

poster

Li, J.

E2f7 and E2f8 are critical partners of RB in development

talk

Liang, F.

Cdc5-dependent Swe1 degradation is required for fear activation in budding yeast

poster

Lilly, M.A.

APC/CFzr/Cdh1 promotes cell cycle progression during endoreplication cycles

talk

Lin, J.

Functional role of two human Rad5 homologs in preventing damage-induced mutagenesis during DNA replication

talk

Lindqvist, A.

Polo-like kinase-1 is activated by Aurora-A to promote checkpoint recovery

poster

Lindsay, C.R.

Daxx and Rassf1 are novel regulators of cellular taxol response

poster

Litovchick, L.

Regulation of the human DREAM complex by post-translational modifications

talk

Liu, H.

The short S-phase spindles in budding yeast during S phase facilitate chromosome capture

poster

liu, h.

The mitotic behavior of the nuclear pore complex is drastically and specifically modified by deletion of non-essential components

poster

Liu, Y.

Somatic cell type specific gene transfer reveals a tumor promoting function for p21Waf1/Cip1

poster

Longworth, M.S.

RBF1 promotes chromatin condensation through a conserved interaction with the condensin II protein, dCAP-D3

talk

Lu, C.

Neuropeptide Y (NPY) induces Y5 receptors-mediated cell polyploidization

poster

Lu, Y.

Dissecting regulatory pathways controlling mitotic exit

poster

Lygerou, Z.

Cdt1 is dynamically recruited onto chromatin at sites of DNA-damage

poster

Lygerou, Z.

Investigating the in vivo role of geminin in lymphoid system development and function

poster

Maddika, S.

Dual role of DYRK2 as an E3-ligase adaptor and a kinase

poster

Maia, A.F.

Molecular interplay between CENP-E and Aurora-B to promote efficient and timely chromosome alignment in prometaphase

poster

Maiorano, D.

Biochemical characterization of the DNA damage checkpoint during early Xenopus development

poster

Malumbres, M.

Control of mammalian development and cell proliferation by APC/C cofactors

talk

Manukyan, A.

Cell size control in mammalian cells

poster

Maresca, T.J.

Live-imaging of a tensiometer cell line reveals novel aspects of tension generation during mitosis

talk

Mark-Danieli, M.

The SIL gene is a centrosomal protein regulating mitotic entry and mitotic checkpoint

poster

Markossian, S.

The nuclear pore complex protein An-Nup2 binds to a novel nucleoporin and is essential for mitosis in A. nidulans

poster

Masamha, C.P.

Elucidation of the roles of cyclin D1 and up- and downstream effectors in the mechanism of SHetA2 induced G1 cell cycle arrest

poster

Masukata, H.

DDK-HP1 interaction is crucial for early replication of heterochromatin regions

talk

Matsumoto, M.

A global map of mitotic phosphoproteome uncovers unexpected signaling pathways in mitosis

poster

Matsumoto, A.

Fbxw7 is essential for G0 maintenance and functions of the stem cells

poster

Mayer, B.

Shugoshin 2 is a Mad1/Cdc20 like binding partner of Mad2

poster

Mazanka, E.M.

The NDR/Lats family kinase Cbk1 directly controls transcriptional asymmetry during cell division

poster

McCleland, M.

RNAi of mitotic cyclins in Drosophila uncouples the nuclear and centrosome cycle

talk

Medendorp, K.

The renal cell carcinoma-associated oncogenic fusion protein PRCCTFE3 induces p21WAF1/CIP1-mediated cell cycle arrest

poster

Méndez, J.

High-density DNA replication timing maps of primary and tumor cells

poster

Merrick, K.A.

Distinct activation pathways promote proper pairing of interphase and mitotic Cdk/cyclin complexes in human cells

talk

Michael, M.

Ordering early events in replication checkpoint activation—TopBP1 recruits DNA polymerase a to stalled replication forks to allow loading of the 9-1-1 clamp and assembly of a checkpoint-signaling complex

talk

Mikolcevic, P.

Mouse Pctk1 is essential for spermatogenesis

poster

Mishra, A.

The role of high affinity interaction of Smc hinge domains for cohesin function

poster

Moore, A.

Does succinate dehydrogenase affect centrosome duplication in C. elegans?

poster

Morgan, D.O.

Positive feedback sharpens the anaphase switch

talk

Murphy, C.M.

A test of the expanding replicon model for cell cycle lengthening at the midblastula transition in X. laevis

poster

Nakayama, K.

Conditional inactivation of Fbxw7 results in a defect in cell cycle exit and tumorigenesis

talk

Nakazawa, N.

Dissection of the essential steps for condensin accumulation at kinetochores and ribosomal DNAs during fission yeast mitosis

poster

Nataraj, S.

Are the catalytic and the stoichiometric functions of cyclin D-Cdk4/6 required equally?

poster

Nezi, L.

Biochemical and genetic analysis of spindle assembly checkpoint in S. cerevisiae

poster

Nicassio, F.

A novel E1A-gene connecting MAPK signaling with G2/M transition

poster

Nicolay, B.N.

The Hippo pathway requires dE2F1 to promote inappropriate cell proliferation

talk

Nishiyama, M.

Epigenetic control of p53 function by CHD8 through recruitment of histone H1

poster

Noguchi, E.

Timeless and Tipin form a mammalian replication fork protection complex and are involved in sister chromatid cohesion

poster

Orr-Weaver, T.L.

Developmental control of the meiotic cell cycle

talk

Osborn, S.L.

Defining the mechanism of FADD-dependent T cell proliferation

poster

Ostapenko, D.

Identification of novel substrates of the anaphase promoting complex (APC)

poster

Otto, T.

Stabilization of N-Myc is a critical and kinase-independent function of Aurora-A in neuroblastoma

talk

Ozaydin, B.

The mechanism of ORC action at a distance

poster

Park, H.

APC/C-Cdh1 mediated proteolysis of the Forkhead Box M1 transcription factor is critical for regulated entry into S phase

talk

Park, J.

Mechanisms of mammalian Polo-like kinase 1 (Plk1) localization—Self-versus non-self priming

poster

Park, S.

Regulation of Cdc6 during two modes of cell cycles in Drosophila

poster

Pasqualato, S.

Control of microtubule-kinetochore attachment in mitosis

poster

Pereira, M.

Molecular characterization of Drosophila kinetochore

poster

Pirino, G.

Dissecting the Cdc25B phosphatase pathway during oocyte maturation

poster

Pontano, L.L.

Genotoxic stress-induced cyclin D1 phosphorylation and proteolysis is required to maintain genome integrity

poster

Prabhu, V.

The effects of aneuploidy on mammalian cell physiology

poster

Pusapati, R.V.

Oncogenes induce DNA damage in vivo leading to the activation of the ATM DNA damage response pathway

poster

Radford, S.J.

Genetic and cytological investigation of meiotic chromosome segregation in Drosophila females

poster

Randall, C.

Regulation of Thr-210 of Polo-like kinase 1 is essential for viability in human cells

poster

Recolin, B.

Role of RPA as sensor of DNA replication checkpoint

poster

Rhind, N.

Regulation of replication origin efficiency and timing by Hsk1/Cdc7

poster

Rivera, T.

Coordinated regulation of ARM and centromeric cohesion by Shugoshin

poster

Roberti, A.

INK4a/ARF locus in metastatic and drug-resistant Burkitt lymphoma cell lines

poster

Rossmann, M.P.

Investigating the role of PCNA in heterochromatin formation

poster

Rubin, S.M.

Parsing the molecular effects of retinoblastoma protein phosphorylation

poster

Ruiz, J.

Meiotic inactivation of Xenopus Myt1 by Cdk/XRINGO but not Cdk/cyclin via site-specific phosphorylation

poster

Russell, P.

Cell cycle control of double-strand break repair

talk

Sadasivam, S.

LIN/MuvB proteins regulate B-Myb chromatin localization and transcription on promoters of G2-M expressed genes

poster

Salvador Marcos, N.

Different S/M checkpoint responses of tumor and non tumor cell lines to DNA replication inhibition

poster

Samoshkin, A.

Condensin has a key role in proper kinetochore positioning relatively to centromere chromatin

poster

Sansregret, L.L.

p110 CUX1 causes tetraploidization

poster

Santamaria, A.

CHICA, a partner of the chromokinesin Kid, is required for Kid loading onto the mitotic spindle

talk

Sasaki, T.

Role of pre-RC assembly in origin specification

poster

Schwacha, A.

Reconstitution of MCM2-7 helicase activity—Involvement of a DNA loading "gate"

talk

Sicinski, P.

"Genetic-proteomic" approaches to study the functions of cyclins in mouse development and neoplasia

talk

Simanski, S.P.

Cell based screening identifies a novel regulator of the anaphase promoting complex

poster

Skibbens, R.V.

BRCA1 and chromosome transmission fidelity genes in S. cerevisiae

poster

Skibbens, R.V.

Interactions between ctf7/eco1 cohesion establishment, cak1 and Cdc28-CDK cell cycle control pathways in S. cerevisiae

poster

Skotheim, J.M.

Positive feedback of G1 cyclins ensures coherent cell cycle entry

talk

Solomon, M.

Pseudosubstrate inhibition of APCCdh1 by Acm1p—Regulation by proteolysis and Cdc28p phosphorylation

talk

Soung, N.

Dual function of hCenexin1 in Plk1/Polo-dependent mitotic function and Plk1-independent ciliogenesis

poster

Sprenger, F.

The anaphase promoting complex/cyclosome (APC/C) is required for re-replication control in endoreplication cycles

talk

Stuart, D.T.

A cyclin domain that confers the ability to trigger pre-meiotic S-phase

talk

Summers, M.K.

The unique N-terminus of the UbcH10 E2 enzyme controls the threshold for APC activation and enhances checkpoint regulation of the APC

talk

Sun, A.

Spa310, a 39-amino-acid molecule derived from the spacer region of pRb2/p130, is able to localize to the nucleus, inhibit the kinase activity of the Cdk2-cyclin E/A complex, and reduce tumor growth in vivo

poster

Susaki, E.

A p27-p57 knock-in mouse model uncovers common and specific roles of p27 and p57

poster

Szilágyi, Z.

A role for the Mediator complex in regulation of cell cycle dependent transcription

poster

Tanaka, K.

Molecular mechanism of the Mrc1 loading onto the replication fork in fission yeast

poster

Tarailo, M.

Enhancers of MDF-1/MAD2 lethality, a model for selective destruction of tumors

poster

Terasaki, M.

A two stage dependence on 1-methyladenine for maturation of starfish oocytes

poster

Toczyski, D.P.

Identifying the molecular role of CDC5 in checkpoint adaptation

talk

Toh, G.

Dynamics of Cdc7, ASK and ASKL1 in live mammalian cells

poster

Toh, Y.

Allosteric regulation of Chk1 by a N-terminal docking domain of p21WAF1

poster

Torres, J.

Cdk1 and PP2A regulate the association of the anaphase promoting complex with spindle poles to promote proper spindle formation

poster

Trickey, M.A.

Rad54, the unassuming controller of homologous recombination

talk

Tseng, B.

The role of microtubule-induced activation of Aurora B in spindle assembly

poster

Ullah, Z.

Inhibition of CDK1 triggers differentiation of trophoblast stem cells into giant cells

poster

Ulrich, H.D.

Activation of DNA damage bypass during replication

talk

van Amerongen, M.J.

E2F4 is required for cardiomyocyte proliferation

poster

van der Sar, S.

Cross-linking biochemistry and proteomics—The yeast spindle checkpoint

poster

van Zon, W.

Concurrent destruction of cyclin B1 and Securin by Cks dependent retention of cyclin B1 at the APC/C

poster

Varmark, H.

Mitotic response to DNA damage

poster

Wagner, M.V.

Analysis of the requirement for Whi5 phosphorylation in inactivation and nuclear export

poster

Walter, J.C.

Biochemical mechanism of replication-coupled DNA interstrand cross-link repair

poster

Wang, L.

Cohesin removal is required for centromere DNA resolution in anaphase

poster

Wang, Y.

Temporal control of the dephosphorylation of Cdk substrates by mitotic exit pathways in budding yeast

poster

Warsi, T.

DNA topoisomerase II is a determinant of the tensile properties of yeast CEN chromatin

talk

Weinl, C.

Mitogen signal transduction leads to tyrosine phosphorylation of the Cdk inhibitor p27Kip1

poster

Welcker, M.

Differential modes of substrate interaction by Fbw7

poster

Wen, H.

Epigenetic regulation of gene expression by Drosophila Myb and E2F2-RBF via the Myb-MuvB/DREAM complex

talk

Whitcomb, E.A.

A new role for UbcH7 in cell cycle progression

poster

Wittenberg, C.