PTEN PATHWAYS & TARGETS

Please scroll to find the status of your abstract.  
Abstracts are listed alphabetically by presenting author.

Presenting Author

Abstract Title

Talk/Poster

Baldwin, M.

Regulation of glioblastoma cell invasion by PKCi and RhoB

poster

Bhatia, J.

Alteration of PTEN function by cancer associated mutations

poster

Bird, M.

Regulation of PTEN by c-Src kinase

poster

Cantley, L.C.

The role of PI 3-kinase in cancer

talk

Cao, L.

Acceleration of wound healing by inhibition of PTEN in mammalian corneal epithelium

poster

Cichowski, K.M.

Torc1 is essential for NF1-dependent malignancies

talk

D'Alessandro, L.A.

HGF-mediated proliferative responses in hepatocytes—Direct and indirect PI3K activation

poster

Downward, J.

Ras and PI 3-kinase signaling in cancer

talk

Eickholt, B.J.

Spatial and temporal regulation of PI3K/PTEN signaling in neurons

talk

Endersby, R.

PTEN-deficiency potentiates tumorigenesis in an orthotopic transplantation model for glioma

talk

Fine, B.

Affinity purification of a PTEN protein complex

talk

Finlay, D.K.

Molecular mechanisms of lymphomagenesis—PTEN deletion drives proliferation via RhoA dependent but PDK1/PKB independent pathways

talk

Foti, M.

PTEN downregulation by unsaturated fatty acids promotes hepatocytes proliferation and carcinogenesis

poster

Furnari, F.

Regulation of PI3K signaling and transformation by PTEN C-terminal-interacting proteins

talk

Georgescu, M.

Control of PI3K/Akt activation by PTEN in glioblastoma multiforme

talk

Gericke, A.

Mutations in PTEN's phosphatase domain affect binding to phosphatidylinositol-4,5-bisphosphate and phosphatidylserine

poster

Gewinner, C.

The inositol polyphosphate 4-phosphatase type II is a novel breast cancer tumor suppressor

talk

Guillermet-Guibert, J.

The p110b phosphoinositide 3-kinase signals downstream of G protein coupled receptors

poster

Huang, X.

Hypomorphic mutation of LKB1 markedly accelerates tumorigenesis in PTEN deficient mice

talk

Jeanclos, E.M.

Active Ras acts as an indispensable adapter and regulator for receptor induced activation of the novel phosphoinositide 3-kinase g isoform, p110g /p97PIKAP

poster

Jo, H.

Small molecule screening to probe the PI3K pathway

poster

Knowles, J.

Phosphoprotein pathway mapping—Analysis of multiple phosphorylation events in the Akt/PI3-kinase signaling pathway using an Akt pathway array

poster

Korkaya, H.

PTEN regulates mammary stem cell fate and survival through PI3-K/AKT and p53 pathways

poster

Lachlan, K.L.

Results of the PTEN related disorders study—42 UK patients with PTEN mutations

poster

Leslie, N.R.

Regulation of PTEN by autodephosphorylation

talk

Li, L.

Stem cells, niches, and zones

talk

Liu, J.

LKB1 regulates the nuclear export of PTEN with or without the AMPK/TSC2/mTOR signaling intermediates

talk

Ma, Y.

Genome-wide kinase library screening for protein kinases with oncogenic potential independent of p110a

poster

Mavrakis, K.J.

Phenotypic screen for oncogenic activities in Akt signaling and translation initiation

talk

Molina, J.R.

Molecular mechanisms of glioblastoma dispersal

poster

Molle, K.D.

A cellular system to identify PTEN-/TSC2-mTOR pathway inhibitors

talk

Moral, M.

Somatic activation of Akt and TP53 deficiency provide a mouse model of human head and neck squamous cell carcinoma

poster

Morales, F.C.

Impaired recruitment of PTEN tumor suppressor to the plasma membrane activates the PI-3 kinase pathway in brain tumor cell lines

poster

Mosessian, S.

Characterizing novel PTEN signaling pathways

poster

Murray, D.

A computational model for the action of PTEN at membrane surfaces

poster

Nardella, C. Dissecting the contribution of the mTOR pathway to prostate tumorigenesis

talk

Newton, A.C.

Phlipping the switch in cell signaling

talk

O'Neill, A.K.

The PHLPP phosphatases regulate growth factor signaling

poster

Plaisier, S.B.

Molecular profiling of murine prostate cancer models for pathway-specific biomarker discovery

poster

Planchon, S.M.

Regulation of the PTEN promoter by statins and SREBP

poster

Reichling, L.J.

Selectivity profiling across the entire PI3 kinase family with the Europium-based universal Adapta™ assay

poster

Sagana, R.

PTEN is required for PGE2 inhibition of a -SMA and collagen production in fibroblasts

poster

She, B.

Dynamic modeling of feedback regulation of PI3K signaling in the hematopoietic system

poster

Shor, B.

A new pharmacological action of CCI-779 involves FKBP12-independent inhibition of mTOR kinase activity and profound repression of global protein synthesis

talk

Siddall, H.K.

Strategies to confer cardioprotection from ischemia-reperfusion injury—Dissecting the PI3K/Akt pathway with genetic silencing and chemical inhibition of PTEN

poster

Silva, R.L.

Dissecting eIF4E action in tumorigenesis

poster

Trotman, L.C.

Identifying novel components of the PTEN signaling network in cancer

talk

Vinciguerra, M.

Unsaturated fatty acids downregulate PTEN expression in hepatocytes through a mTOR/NF-k B-depedent synthesis of microRNA-21

poster

Wullschleger, S.

Role of PI(3,4)P2 binding to TAPP1/TAPP2 defined by knockin mutation

poster

Yuan, T.L.

The role of the class 1A PI3Ks in vasculogenesis and tumor angiogenesis

poster

Zhu, G.

Postnatal deletion of PTEN in neural stem/progenitor cells results in neuronal migration defects and expansion of the subventricular zone

poster

 

Cold Spring Harbor Laboratory
Meetings & Courses Program
PO Box 100, 1 Bungtown Road
Cold Spring Harbor, NY 11724-2213
Phone (516) 367-8346
Fax: (516) 367-8845

meetings@cshl.edu