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General Information

Travel Info

Campus Info

Special meeting of the CSHL Genentech Center
for the History of Molecular Biology and Biotechnology

History of Restriction Enzymes
Cold Spring Harbor Laboratory, New York
October 19 - 21, 2013
Registration Deadline: October 15, 2013

Herb Boyer, University of California, San Francisco
Stu Linn, University of California, Berkeley
Mila Pollock, Cold Spring Harbor Laboratory
Richard Roberts, New England BioLabs Inc.,

The CSHL Genentech Center for the History of Molecular Biology and Biotechnology is pleased to announce a special meeting on the History of Restriction Enzymes, which will be held at the Cold Spring Harbor Laboratory. The meeting will begin at 7.30pm on the evening of Saturday, October 19, and will conclude after lunch on Monday, October 21.

As enzymes that cleave DNA at specific recognition sites, the Type II restriction enzymes are among the workhorses of molecular biology, genetics, and biotechnology. Following their discovery in 1970 a flurry of activity led to their use on many fronts including mapping Restriction Fragment Length Polymorphisms and laid the basis for studies of molecular evolution. More than 3,000 restriction enzymes are known today, of which more than 625 are commercially available.

This international meeting on the history of restriction enzymes will cover research on restriction enzymes dating back to the phage and plasmid (R factors, etc.) work of the 1950s.The scope of the meeting will be quite broad and will cover the original discoveries in the field, the early characterization of the various types of restriction-modification systems and the subsequent cloning and sequencing of the genes encoding these systems including the latest discoveries that are being facilitated by SMRT sequencing. The importance of the commercialization of the Type II restriction enzymes and their subsequent uses will also be highlighted.

Speakers will include scientists who made key discoveries regarding restriction enzymes, as well as students and collaborators of those scientists, historians and philosophers of science, chroniclers of the biotech industry, and archivists from the institutions where the groundbreaking work on restriction enzymes was carried out.

The Beginnings of the Restriction Enzyme Field
The Field Begins to Grow
Restriction Enzymes Become Reagents
Cloning Restriction Enzyme Genes
The Biochemistry of Restriction Enzymes
Structural Studies
Short Contributions and panel discussion
History of the Field and Summary

Aneel Aggarwal, Mount Sinai School of Medicine
Werner Arber, University of Basel, Switzerland
Tom Bickle, University of Basel, Switzerland
Herb Boyer, San Francisco
Xiaodong Chen, Emory University
Jack Chirikjian, Georgetown University
Don Comb, New England BioLabs
Steve Halford, Bristol University, United Kingdom
Ken Horiuchi, The Rockefeller University
Clyde Hutchison, J. Craig Venter Institute
Arvydas Janulaitis, Institute of Biotechnology, Lithuania
Stu Linn, UC Berkeley
Bill Linton, Promega
Arvydas Lubys, Thermo Fisher Scientific, Baltics, UAB
Matthew Meselson, Harvard University
Rick Morgan, New England BioLabs
Andrzej Piekarowicz, Warsaw University, Poland
Alfred Pingoud, Institute of Biochemistry - Giessen, Germany
Mila Pollock, Cold Spring Harbor Laboratory
Rich Roberts, New England BioLabs
John Rosenberg, University of Pittsburgh
Ira Schildkraut, New England Biolabs
Ham Smith, J. Craig Venter Institute
Bruno Strasser, Yale University & University of Geneva
Geoff Wilson, New England BioLabs
Bob Yuan, University of Maryland

While abstracts are NOT being accepted for this meeting, we invite participants who would like to present posters at the meeting to alert us via email to Plan on a maximum size of 4ft x 4ft (1.22m x 1.22m) for your poster.

We have applied for funds from industry and other sponsors to partially offset attendance costs for those in real financial need. Apply in writing to Demetria Mudar ( stating your need for financial support.

We look forward to seeing you at Cold Spring Harbor in October.

Major support provided by: Life Technologies, New England Biolabs, ThermoFisher
Significant support provided by: Genentech, Nippon, Promega, TAKARA/Clontech
Additional support provided by: Molecular Biology Resources

Regular Pricing
Academic Package $700
Graduate/PhD Student Package $575
Corporate Package $900
Academic/Student No-Housing Package $475
Corporate No-Housing Package $600

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Regular packages are all inclusive and cover registration, food, housing, parking, social, lobster dinner, etc. No Housing packages include all costs except housing. Full payment is due 4 weeks prior to the meeting.



Cold Spring Harbor Laboratory
Meetings & Courses Program
PO Box 100, 1 Bungtown Road
Cold Spring Harbor, NY 11724-2213
Phone (516) 367-8346
Fax: (516) 367-8845