YEAST GENETICS & GENOMICS
July 27 - August 16, 2010
Application Deadline: March 15, 2010

Instructors:
Beverly Errede, University of North Carolina Chapel Hill
Jackie Vogel, McGill University
Jeffrey Smith, University of Virginia

See the roll of honor - who's taken the course in the past

The Yeast Genetics & Genomics course is a modern, state of the art laboratory course designed to teach the students the full repertoire of genetic approaches needed to dissect complex problems in the yeast Saccharomyces cerevisiae. Combinations of classical genetic approaches are emphasized, including the isolation and characterization of mutants, tetrad analysis, complementation, and mitotic recombination. Molecular genetic techniques, including various types of yeast transformation, gene replacement with plasmids and PCR, construction and analysis of gene fusions, and generation of mutations in cloned genes, will also be emphasized. Students will use classical and molecular approaches to gain experience in identifying and interpreting various kinds of genetic interactions including suppression and synthetic lethality. Students will be immersed in yeast genomics and will perform and interpret experiments with DNA arrays. Students will gain first-hand experience in modern cytological approaches such as epitope tagging and imaging yeast cells using indirect immunofluorescence, GFP-protein fusions and a variety of fluorescent indicators for various subcellular organelles. Lectures on fundamental aspects of yeast genetics will be presented along with seminars given by outside speakers on topics of current interest.

Last year's speakers included:
Dan Burke, University of Virginia
Duncan Clarke, University of Minnesota
Kara Dolinski, Princeton University
Gerald Fink, Whitehead Institute for Biomedical Research/MIT
Thomas Fox, Cornell University
Timothy Hughes, University of Toronto
Maria Kilfoil, McGill University
Susan Lindquist, Whitehead Institute for Biomedical Research
Frank Luca, University of Pennsylvania
Stephen Michnick, Universite de Montreal
Jeff Smith, University of Virginia
Jeremy Thorner, Univ, of Calif., Berkeley
Jonathan Warner, Albert Einstein College of Medicine
Virginia Zakian, Princeton University

This course is supported with funds provided by National Human Genome Research Institute and the Howard Hughes Medical Institute

Cost (including board and lodging): $4,250
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