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C. ELEGANS
August 9 - 24
Application Deadline: March 15, 2008

Instructors:
Shawn Ahmed, University of North Carolina

Arshad Desai, University of California San Diego
Mei Zhen, Samuel Lunenfeld Research Institute, Canada

This course is designed to familiarize investigators with C. elegans as an experimental system, with an emphasis on both classical genetic analysis and reverse genetic approaches. A major goal is to teach students how to successfully exploit the information generated by the C. elegans genome project. The course is suited both for those who have a current training in molecular biology and some knowledge of genetics, but have no experience with C. elegans, as well as students with some prior worm experience who wished to expand their repertoire of expertise. The following topics will be covered both in the laboratory and by lectures from experts in the field: worm pushing, C. elegans databases and worm bioinformatics, anatomy and development, forward genetics, chemical and transposon mutagenesis, generation of transgenic animals, expression pattern analysis, reverse genetics, construction and screening of deletion libraries, and RNA inactivation. The course is designed to impart sufficient training to students in the most important attributes of the C. elegans system to enable students to embark on their own research projects after returning to their home institutions.

Speakers in the 2007 course included:
Andrew Dillin, The Salk Institute for Biological Studies
Monica Driscoll, Rutgers University
Marie-Anne Felix, Institut Jacques Monod, CNRS, France
Andrew Fraser, The Wellcome Trust Sanger Institute, UK
Barth Grant, Rutgers Univesity
Jonathan Hodgkin, University of Oxford, UK
Geraldine Seydoux, Johns Hopkins University School of Medicine
Kang Shen, Stanford University
John White, University of Wisconsin, Madison

This course is supported with funds provided by the National Institute of Child Health and Human Development

Cost (including board and lodging): $3,555
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