C.
ELEGANS
August 9 - 24
Application Deadline: March 15, 2008
Instructors:
Shawn
Ahmed, University of North Carolina
Arshad
Desai, University of California San Diego
Mei
Zhen, Samuel Lunenfeld Research Institute, Canada
This
course is designed to familiarize investigators with C.
elegans as an experimental system, with an emphasis
on both classical genetic analysis and reverse genetic approaches.
A major goal is to teach students how to successfully exploit
the information generated by the C. elegans genome
project. The course is suited both for those who have a
current training in molecular biology and some knowledge
of genetics, but have no experience with C. elegans, as
well as students with some prior worm experience who wished
to expand their repertoire of expertise. The following topics
will be covered both in the laboratory and by lectures from
experts in the field: worm pushing, C. elegans
databases and worm bioinformatics, anatomy and development,
forward genetics, chemical and transposon mutagenesis, generation
of transgenic animals, expression pattern analysis, reverse
genetics, construction and screening of deletion libraries,
and RNA inactivation. The course is designed to impart sufficient
training to students in the most important attributes of
the C. elegans system to enable students to embark
on their own research projects after returning to their
home institutions.
Speakers
in the 2007 course included:
Andrew Dillin, The Salk Institute
for Biological Studies
Monica Driscoll, Rutgers University
Marie-Anne Felix, Institut Jacques Monod, CNRS, France
Andrew Fraser, The Wellcome Trust Sanger Institute, UK
Barth Grant, Rutgers Univesity
Jonathan Hodgkin, University of Oxford, UK
Geraldine Seydoux, Johns Hopkins University School of Medicine
Kang Shen, Stanford University
John White, University of Wisconsin, Madison
This course is supported with funds provided by
the National
Institute of Child Health and Human Development
Cost
(including board and lodging): $3,555
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