PTEN Pathways
March 15 - 19, 2006
Abstract Deadline: January 20, 2006

Organizers:
Carlos Cordon-Cardo, Memorial Sloan-Kettering Cancer Center
Pier Paolo Pandolfi, Memorial Sloan-Kettering Cancer Center
Ramon Parsons, Columbia University
William Sellers, Dana-Farber Cancer Institute

Typical Program

We are pleased to announce the first Cold Spring Harbor conference on PTEN Pathways, which will begin at 7:30 pm on Wednesday, March 15 and run through lunch on Sunday, March 19, 2006. This meeting is intended to build on the first international PTEN conference held in Scotsdale, Arizona in 2004.

The 2006 meeting is intended to bring together a diverse group of scientists studying various molecular, genetic and biochemical approaches to the analysis of the PTEN pathway in cancer, diabetes, and neurological disorders such as Parkinson’s Disease. Junior and senior researchers will join to discuss their latest research findings and technical approaches toward the analysis of the PTEN pathway. Particular emphasis will be given to human cancer pathogenesis, disease models, and therapy. While a number of speakers have been invited, please note that the majority of oral presentations will be drawn from openly submitted abstracts.

Tentative Topics:
* PTEN/PI-3 kinase pathway alterations in human cancer
* PTEN regulation
* PI-3 kinase, IRS, PDK1 & AKT signaling
* FOXO signaling
* TSC and mTOR signaling
* PTEN pathway & neurodegenerative/metabolic diseases
* Analysis of pathway mutations in mice & preclinical therapeutics
* Therapy

Session Chairs / Invited Speakers:
Asa Abeliovich, Columbia University
Domenico Accili, Columbia University
Dario Alessi, University of Dundee, UK
Suzanne Baker, St. Jude’s Children Research Hospital
Anne Brunet, Harvard Medical School
Lewis Cantley, Harvard Medical School
Peter Devreotes, Johns Hopkins University
Peter Downes, University of Dundee, UK
Charis Eng, The Ohio State University
Maria-Magdalena Georgescu, University of Texas MD Anderson Cancer Center
Brian Hemmings, Friedrich Miescher-Institut, Switzerland
Eric Holland, Memorial Sloan Kettering Cancer Center
Scott Lowe, Cold Spring Harbor Laboratory/HHMI
Tak Mak, AMDI OCI University Health Network, Canada
Gordon Mills, University of Texas MD Anderson Cancer Center
Neal Rosen, Memorial Sloan Kettering Cancer Center
David Sabatini, Whitehead Institute for Biomedical Research
Leslie Shaw, Beth Israel Deaconess Medical Center
George Thomas, University of Cincinnati
Morris White, Harvard Medical School

Abstracts should contain only new and unpublished material and must be submitted electronically by the abstract deadline. Selection of material for oral and poster presentation will be made by the organizers and individual session chairs. Status (talk/poster) of abstracts will be posted on our web site as soon as decisions have been made by the organizers.

We are eager to have as many young people as possible attend since they are likely to benefit most from this meeting. We have applied for funds from government and industry to partially support graduate students and postdocs. Apply in writing to meetings@cshl.edu stating need for financial support - preference is given to those submitting abstracts.

We look forward to seeing you at Cold Spring Harbor in March.

This conference is supported in part by funds provided by: National Cancer Institute

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Regular packages are all inclusive and cover registration, food, housing, parking, wine-and-cheese party, lobster banquet, etc. No Housing packages include all costs except housing. Full payment is due 4 weeks prior to the meeting.